• Journal of Korea Foundry Society
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• v.38 no.1
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• pp.16-26
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• 2018

In this study, the effects of the pouring temperature, preheating temperature, surface condition and fraction of the wear resistant part on the production of duo-castings were investigated using a high Cr white cast iron with excellent abrasion resistance and a low Cr alloy steel with good toughness. The constituent materials of the duo-castings were designed to have high hardness, fracture toughness and abrasive wear resistance for the replacement of high Mn alloy steels with low abrasive wear resistance. In particular, the amount of abrasive wear of 17% Cr white cast iron was about 1/20 of that of high Mn alloy steel. There was an intermediate area of about 3mm due to local melting at the bonding interface of the duo-castings. These intermediate regions were different from those of the constituent materials in chemical composition and microstructure. This region led to fracture within the wear resistant part rather than at the bonding interface in the bending strength test. The bending fracture strengths were 516-824 MPa, which were equivalent to the bending proof strength of high Mn steel. The effects of various casting conditions on the duo-cast behavior were studied by simple pouring of low Cr alloy steel melt, but the results proved practically impossible to manufacture duo-castings with a sound bonding interface. However, the external heating method was suitable for the production of duo-castings with a sound bonding interface.

• Journal of Korea Foundry Society
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• v.20 no.3
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• pp.167-172
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• 2000

Squeeze casting was performed to fabricate the SiC whisker reinforced magnesium matrix composites, and the suitability of the squeeze casting for the production of the sound composites was determined by micro/macro-structures observations and tensile test. The two-directional infiltration of the melt and the removal of air during infiltration using the devised mold were necessary to produce the composites. The pressure of 100 MPa was effective for the production of composites with the SiC whisker volume fraction of 30%, but the pressure should be lower than 50 MPa in case of below 20% in the volume fraction. The SiC whiskers in the squeeze cast composites were randomly and densely aligned, and the SiC whiskers/magnesium interfaces were continuously well-bonded. The elastic modulus, 0.2% proof stress and tensile strength in the composite were about 2.5times, l0times and 4times as large as those of magnesium, respectively, indicating that the squeeze casting sufficiently provides the high strength magnesium composites reinforced with SiC whiskers.

• Journal of Fisheries and Marine Sciences Education
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• v.21 no.3
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• pp.373-389
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• 2009

The aims of this study are to examine urgent problems for reorganization into future-proof large purse seine fisheries in order to positively cope with rapidly changing domestic and foreign fisheries circumstances. First, this paper provides current situations of the large purse seine fisheries. The current situations of it are composed of fisheries influence such as vessel number, vessel power, and fisher number, use of resource and fishing places, and changes in products and sales of species caught by the large purse seine. Secondly, this paper reviews current problems of the large purse seine fisheries including cost reduction and increase of value added. Thirdly, this paper suggests basic development direction and countermeasures for strengthening competitiveness of the large purse seine fisheries. In conclusion, urgent problems of the larger purse seine fisheries can be summarized as inefficiency of distribution structures and retarded landing system and facilities as well as the worse of profitability according to shrink of fishing places, reduction of products, lack of workers, and increase in oil price. To solve the urgent problems, the large purse seine fisheries should be changed into an industry with low cost and high efficiency, and also need to introduce of new production system, strengthen autonomous management of natural resource, and increase in value added to products.

• Journal of Microbiology and Biotechnology
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• v.32 no.5
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• pp.621-629
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• 2022

Bacterial outer membrane vesicles (OMVs) typically contain multiple immunogenic molecules that include antigenic proteins, making them good candidates for vaccine development. In animal models, vaccination with OMVs has been shown to confer protective immune responses against many bacterial diseases. It is possible to genetically introduce heterologous protein antigens to the bacterial host that can then be produced and relocated to reside within the OMVs by means of the host secretion mechanisms. Accordingly, in this study we sought to develop a novel platform for recombinant OMV (rOMV) production in the widely used bacterial expression host species, Escherichia coli. Three different lipoprotein signal peptides including their Lol signals and tether sequences-from Neisseria meningitidis fHbp, Leptospira interrogans LipL32, and Campylobactor jejuni JlpA-were combined upstream to the GFPmut2 model protein, resulting in three recombinant plasmids. Pilot expression studies showed that the fusion between fHbp and GFPmut2 was the only promising construct; therefore, we used this construct for large-scale expression. After inducing recombinant protein expression, the nanovesicles were harvested from cell-free culture media by ultrafiltration and ultracentrifugation. Transmission electron microscopy demonstrated that the obtained rOMVs were closed, circular single-membrane particles, 20-200 nm in size. Western blotting confirmed the presence of GFPmut2 in the isolated vesicles. Collectively, although this is a non-optimized, proof-of-concept study, it demonstrates the feasibility of this platform in directing target proteins into the vesicles for OMV-based vaccine development.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.581-586
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• 2017

The facility modernization policy has been established to improve fruits quality and to increase fruits yield per acreage. The fruit production quantity of farms joined in the policy was increased. Therefore, many fruit farms want to participate in the policy. The government has subsidized fruit farms to modernize their facilities such as rain proof, drainage way, frost proof, etc. This study analyzes the performance of the facility modernization policy focused on apple, eastern pear, and grape cultivation sector. One hundred apple farms, one hundred eastern pear farms, and 91 grape farms were surveyed. The performance of the policy was reviewed using analytical technique such as Covariate Matching and Propensity Score Matching and several policy implications were suggested.

• Korean Journal of Biological Psychiatry
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• v.1 no.1
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• pp.98-108
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• 1994

The etiology and pathophysiology of schizophrenia remain unknown. It has been postulated that infectious-autoimmune process may play a role in the pathogenesis of symptoms in some schizophrenic patients. Findings of altered interleukin(IL) regulation have been regarded as additional proof that schzophrenia has an infectious-autoimmune background. In the present study, we measured mitogen-stimulated production of and serum level of IL-$1{\beta}$, IL-2, IL-6 using ELISA in 16 neuroleptic-free schizophrenic patients and in 16 age, sex matched healthy controls. The results were as follows : 1) There was a significant decrease of IL-2 production in schizophrenic patients than in normal controls(respectively $1.90{\pm}0.13ng/m{\ell}$, $2.79{\pm}0.14ng/m{\ell}$, p<0.001). But there was no significant difference of IL-$1{\beta}$ production and IL-6 production between schizophrenic patients and normal controls. 2) There was a significant increase of serum level of IL-2 in schizophrenic pateitns than in normal controls(respectively $184.8{\pm}12.8pg/m{\ell}$, $104.2{\pm}34.2pg/m{\ell}$, p<0.01). Serum level of IL-$1{\beta}$ was partially detected in both groups and serum level of IL-6 was not detected in both groups. 3) There was no significant differences of IL-$1{\beta}$, -2, -6 production & serum level of IL-2 according to male vs female, paranoid type vs undifferentiated type, drug-naive group vs drug-free group in schizophrenic patients. 4) There was significant correlation between IL-$1{\beta}$ and IL-6 production(r=0.86, p<0.001). No correlation between IL-$1{\beta}$, -2, -6 production, serum level of IL-2 and age, duration of illness, and BPRS score was found. It has been suggested that the low lymphocyte production of IL-2 in the patients with autoimmune disease occurs because the T cells are activated and lymphocyte-derived IL-2 has been released into the serum. The authors suggest that decreased IL-2 production in our schizophrenic patients is due to increased IL-2 serum level in those patients. Thus our finding of low IL-2 production and high serum level of IL-2 in our schizophrenic patients is compatible with the possibility that our patients have an autoimmune process. Further study on relationship between IL alteration and other immunological abnormalities(the presence of serum autoantibody and of anti-brain antibody, $CD4^+$, $CD8^+$ cell index, etc) in schizophrenic patients will be warranted.

• Proceedings of the Korea Concrete Institute Conference
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• 1993.10a
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• pp.207-212
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• 1993

When constructing highly precise production plants, for example, super LSI plants or semiconductor plants, it is important to take the necessary control countermeasures into consideration to obtain the working microvibration environment, which is directly related to product precision. Working environment of a clean room means vibration-free and there are only ultra-miro vibration which human cannot sense. In order to provide an place having a vibration-free working environment with only ultra-micro vibration it is necessary to posses a great number of vibration isolation technlogies, wide-ranging and abundant survey and teat data, and a high level of knowledge enabling comprehensive judgments to be made. In this study, experimental modal analysis is used to analyze the dynamic characteristics of double floor for vibration-proofing near apparatus which generate vibration. It is concluded that the double floor system with rubber pad inserted between floor panel and pedestal is good for vibration proof.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2005.10a
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• pp.85-90
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• 2005

A Water Level gauge which composes a water supply system for water demand, information transmission system and the solar storehouse electromotive floodgate, regarding the structure plan and a production of the nothing power automatic floodgate it described. The important point must solve but urgently will compare the water amount used from system establishment place or not one. and It must give proof the efficient characteristic of system, must solve the technical problem portion against revision of the accuracy of upper downstream canal which is information transmission system of the Self-controlled check gate. The solar floodgate is more economic with the base which will reach and the system construction which is accurate.

• Journal of the Korean Graphic Arts Communication Society
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• v.24 no.2
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• pp.69-78
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• 2006

Proofing is one of the inspection operations of printing and can be considered a process control step. The three main kinds of proofs are press proofs, photomechanical proofs, and digital proofs. Photomechanical and digital proofs are also generally refered to as "off-press" proofs. Off-press color proofs are more economical than press proofs. Digital proofs offer fast production time along with a much lower cost per page. Hard-copy digital proofs can be output using thermal transfer printers, ink jet printers, and color laser copiers, as well as dye sublimation and electrophotographic technology. Ink jet method is commonly using because of the reasonal price. But ink jet system is difficult to reproduce an exact color proof. This research was carried out for the purpose of optimization of ink jet color proofing, using two kinds of ink jet printers with 6 colors (C, M, Y, K, mC, mM) and 4 colors (C, M, Y, K) system.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2019.05a
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• pp.137-138
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• 2019

To overcome the limitation in relation to thermal insulator's selection and installation method that is suitable for exterior insulation and waterproof construction methods, a production basis of thermal insulators of which manufacturing knowhow is held by companies was ensured and future-oriented construction methods to adopt new materials were applied. Performance verification was conducted through performance and mock-up tests of thermal transmittance on the cross sections where the flexible insulators were applied based on the improved prototype and performance data were obtained. To overcome the biggest drawbacks (walking feeling and damage etc.) in the exterior insulation and waterproof construction method, inserting a protective layer between thermal insulator and water-proof layer was proposed, and polypropylene corrugated cardboards.