• 제목/요약/키워드: promotion step

검색결과 265건 처리시간 0.025초

Control and Mechanism of Tumor Promotion in UV-Carcinogenesis

  • Ueda, Masato;Budiyanto, Arief;Ashida, Masashi;Bito, Toshinori;Ichihashi, Masamitsu
    • Journal of Photoscience
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    • 제9권2호
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    • pp.221-224
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    • 2002
  • Carcinogenesis can be theoretically divided to intiation step and promotion step. Intiation associates with genetic alterations including p53 tumor suppressor gene and ras oncogene. Promotion involves in clonal expansion of of an initiated cell by epigenetic mechanism, mainly through signal transduction and gene expression. Ultraviolet light (UV) acts as both initiator and promoter. Initiation is closely related with DNA damage induced by UV, including cyclobutane pyrimidine dimers, (6-4) photoproducts and 8-hydroxy-2'-deoxyguanosine. Cyclobutane pyrimidine dimers and (6-4) photoproducts are directly induced by UV, while 8-hydroxy-2'-deoxyguanosine is induced indirectly by the reactive oxygen species. Because initiation is an irreversal genetic event, while promotion is a reversal and epigenetic event, to know the molecular mechanisms of tumor promotion in UV-carcinogenesis is crucial to develop preventive medicine and suppress UV-carcinogenesis. Because ROS is also involved in signal transduction of the cell, anti-oxidant could be the good candidate of anti-promoting agent. Here, we describe the suppressive effect of UV-carcinogenesis by various anti-oxidant including olive oil. In addition, we discuss about the mechanism of UVB-induced expression of cyclooxygenase-2, which might be a representative molecule involved in promotion of UV-carcinogenesis.

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보건분야 치과위생사들의 건강증진사업을 위한 전문교육 필요도 조사 (A Study on Dental Hygienists' Needs for Specialized Education in Health Promotion Projects)

  • 황윤숙
    • 한국치위생학회지
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    • 제7권4호
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    • pp.611-625
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    • 2007
  • The purpose of this study was to analyze dental hygienists' opinions on health promotion projects in public health and their needs for specialized education in the projects, so that it could help prepare specialized education program required for health promotion projects in the future. To meet the goals, total 364 dental hygienists working in public health were asked to join a questionnaire survey via e-mail in September 2007 for data analysis. As a result, this analysis came to the following conclusions: First, it was found that 29.9% of total respondents took in charge of health promotion projects, and 26.9% respondents considered it very necessary to be responsible for the health promotion projects(56.0% considered it necessary). Almost half respondents considered nonsmoking assistance most desirable task(48.4%) and foremost demanded(50.5%) out of all current health promotion projects, 39.8% respondents answered that they could carry on health promotion task, if assigned, after completing occupational training course. Second, it was found that 39.3% respondents acquired other licenses and qualifications than certificate of registered dental hygienist, and their medical licenses or qualifications included certificate of nursing assistant(18.7%) and certificate of social worker(11.8%) by category. Third, in terms of opinions on possible ways to facilitate health promotion projects, it was found that over half respondents considered it recommended to step up specialized education(56.9%) and prepare legal basis and administrative system(53.6%). Notably, 90.7% respondents considered it necessary to step up specialized education in health promotion. Fourth, in terms of opinions on participation in health promotion projects, it was found that almost half respondents(49.7%) considered it necessary and very positive for extending dental hygienists' works in the future. Moreover, in terms of reasons for sum positive answers, it was found that many respondents considered it helpful for appointment(41.8%) and contributing to capability development and job satisfaction(44.5%). In terms of opinions that sud, participation would be unnecessary, 29.7% respondents thought that nothing would be changed in their dental health projects even with reduced number of public health dentists, and 31.3% respondents thought that dental hygienists are professional manpower responsible only for dental health works. Finally, in terms of on-the-job training(OJT) related to health promotion, it was found that 92.9% respondents desired for OJT. In terms of experiences in OJT, 79.9% respondents answered that they never joined OJT course. In other words, only 20.1% respondents joined OJT courses for health promotion task, such as nonsmoking assistance(8.8%), health promotion FMTP training(2.2%), exercises(1.4%) and nutrition(0.6%).

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제주도 해양레저장비산업 육성 방안에 대한 고찰 (A Study on the Development Strategy of Jeju Marine Leisure Equipment Industry)

  • 이영진;송영민
    • 수산해양교육연구
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    • 제24권2호
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    • pp.286-301
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    • 2012
  • This study was to consider the development strategy of Jeju Marine leisure equipment industry for facilitating marine leisure tourism industry. For achieving this goal, the case studies related to domestic & foreign marine leisure equipment industry, interviews of marine leisure equipment company, the contents of specialist consultation meeting were used in this study. The strategies for promoting were suggested in progress that step 1 was the expansion of maintenance infrastructure as of a port of call, step 2 was the establishing of marie leisure tourism image, step 3 was the integration of marine leisure equipment industry. More specific suggestions were followed. As an aspect of infrastructure, the expansion of management of marine leisure equipment such as yacht, development of marina having similar image of Jeju were suggested. As an aspect of law/institution, the development of financial support system on the marine leisure equipment, promotion of establishment of professional education institutions were suggested. As an aspect of contents/programs, the hosting the exhibition of marine leisure used equipment of international trade, the development of environmental-friendly program associated with cruise were suggested, Finally, as an aspect of promotion/marketing, the promotions linked with drama & movie industry, the strategy of improvement of negative image to the yacht industry were suggested.

초등학교 구강보건교육을 위한 코스웨어 개발 (Development of Wed-Based Courseware in Oral Health Education for Elementary School Children)

  • 최빈아;장창곡
    • 보건교육건강증진학회지
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    • 제20권2호
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    • pp.1-18
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    • 2003
  • The purpose of this study was to develop game style courseware in oral health instruction for elementary school children. The manufacturing equipment and languages which were used to develop the courseware were: Photoshop version 7.0, Illustrator version 10.0, HTML, Dream Weaver MX, Editplus, CSS and Java - script. The data base was built up by using PHP and mySQL over Internet Explorer version 4.0. The contents of courseware for oral health education were based on the list of oral health affaires of the Department of Health and Welfare, 2002. The story of the game ‘Saving Hayani locked down in a castle of a cavity man’ was developed for the learners to learn oral health by inducing learning motivation. A character named ‘Chan i’ was introduced to the learners to be more friendly with the program while they were learning. As the game was made of three step education levels, the learner most pass the prepared test given at each step to advance to a higher level. A database connected to web was constructed to store the scores the learners earned at each step. In conclusion, the courseware will help the elementary school children learn oral health care efficiently through the internet regardless of time and space.

보건의료체계에 대한 소고 (The review of Health Care System)

  • 정영일;강성홍
    • 보건교육건강증진학회지
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    • 제9권2호
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    • pp.89-102
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    • 1992
  • This study is aimed both to define a conception of Health Care Systems and to suggest Desirable Reorganization Directions in Korea. The Desirable Reorganization Directions of Health Care System in Korea is as follows ; 1. The Health Care System of Free Market System has to reorganize step by step for the Directions of National Health System. 2. The Health Care System has to reorganize with local socite as the center of local community. Especially, Health Sub-Center should be reorganized to provide Compresensive Health Care, so that the Sub-Center consist at least 15 members of health workers including a chief of governmental office. 3. The Health Care System has to reorganize for the Directions responding problems of the Elder, New Medical Technology Development, and Health Information System.

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지역사회 대상의 개인별 건강상담서비스 프로그램 중재 효과: 건강원스톱서비스 사업 (Effects of an Individual Health Counseling Program for Community: Health One-stop Service Program)

  • 김현;이석구
    • 보건교육건강증진학회지
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    • 제29권2호
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    • pp.13-21
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    • 2012
  • Objectives: The aim of the study was to identify the effects of a community-level individual health counseling program for community. Methods: Data included baseline demographics, blood pressure, blood sugar, waist circumference, total cholesterol and health behavior index(body mass index, dietary practice guidelines score, physical activity, high-risk drinking) collected at public health centers in Chungnam province from January to September, 2011. Data obtained from the individual health counseling program in Chungnam province were analyzed using Wilcoxon Signed Rank Test and McNemar Test. Results: After the individual health counseling intervention, the results of health measurement index; systolic blood pressure, diastolic blood pressure, total cholesterol, waist circumference decreased in the health risk group, while total cholesterol and waist circumference decreased in the disease management group. Health behavior change in both groups. Body mass index, moderate physical activity, dietary practice guidelines scores were improved. Conclusions: These results indicate that the individual health counseling program for community was effective in improving health behaviors and status. The results demonstrate that step-by-step counseling program development and intervention studies are needed.

현장실태조사를 통한 건설기술진흥법 상 안전관리계획서의 개선방향에 대한 연구 (A Study on the Improvement of the Safety Management Plan under the Construction Technology Promotion Act by Field Survey)

  • 윤영근;이명구;오태근
    • 한국안전학회지
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    • 제33권4호
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    • pp.30-37
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    • 2018
  • Although the safety management plan review system according to the Construction Technology Promotion Act for securing the safety of the construction work is a fundamental system essential for the prevention of the construction industry disaster, the necessity of its improvement has been raised because it often fails to meet the original purpose. In this study, through the analysis of the effect of the safety management plan and the problems of the operation, we suggest ways to improve it in view of the construction accident reduction and conducted surveys on the construction site through the questionnaires of the client, construction company, and construction business technology manager. In order to improve the effectiveness of this system as a result of the study, it is necessary to distribute the guidelines for the preparation of the safety management plan, manuals, etc., to simplify the contents of the safety management plan, also the step-by-step approval of the safety plan can be a solution. For this, it is necessary to revise the policy through consultation with the Ministry of Land, Transport and Maritime Affairs and related experts.

자연 산화물 분산 촉진에 의한 실 시간 인 도핑 실리콘의 고품질 에피택셜 저온 성장 (High-Quality Epitaxial Low Temperature Growth of In Situ Phosphorus-Doped Si Films by Promotion Dispersion of Native Oxides)

  • 김홍승;심규환;이승윤;이정용;강진영
    • 한국전기전자재료학회논문지
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    • 제13권2호
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    • pp.125-130
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    • 2000
  • Two step growth of reduced pressure chemical vapor eposition has been successfully developed to achieve in-situ phosphorus-doped silicon epilayers, and the characteristic evolution on their microstructures has been investigated using scanning electron microscopy, transmission electron microscopy, and secondary ion mass spectroscopy. The two step growth, which employs heavily in-situ P doped silicon buffer layer grown at low temperature, proposes crucial advantages in manipulating crystal structures of in-situ phosphorus doped silicon. In particular, our experimental results showed that with annealing of the heavily P doped silicon buffer layers, high-quality epitaxial silicon layers grew on it. the heavily doped phosphorus in buffer layers introduces into native oxide and plays an important role in promoting the dispersion of native oxides. Furthermore, the phosphorus doping concentration remains uniform depth distribution in high quality single crystalline Si films obtained by the two step growth.

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지역주민 참여에 영향을 미치는 건강증진사업 지원요인 -일개 광역시 일 만보 걷기사업을 중심으로- (Supporting Factors Affecting Citizen Engagement in Community Health Promotion Program -Focused on 10,000-Step Walking Program of a Metropolitan City-)

  • 문선미;강소영
    • 한국콘텐츠학회논문지
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    • 제16권8호
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    • pp.529-539
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    • 2016
  • 본 연구는 지역사회 건강증진사업에서 주민참여에 영향을 미치는 사업지원요인을 규명하기 위한 서술적 연구이다. B시에서 주최한 3개월간 일만보 걷기사업을 중도에 포기하지 않고 끝까지 참여한 지역주민 418명을 대상으로 하였다. 자료는 자기보고식 설문지를 이용하여 수집하였고, T검정과 분산분석, 다중회귀분석으로 분석하였다. 사업 참여자 중 물리적 지원(만보기(p<.001), 걷기기록장(p<.001), 실천저금통(p=.002))을 이용하거나, 정보적 지원(걷기교육, 주민리더교육)에 참여하거나(p<.001), 촉진행사 및 모임(보건소별 걷기모임)에 참여횟수가 많거나(p<.001), 파트너십(걷기 동아리에 소속된 경우)에 따라서(p<.001) 걷기 참여일수는 통계적으로 유의한 차이가 있었다. 또한 걷기 기록장 사용, 동아리 소속이 걷기 참여의 유의한 영향요인으로 나타났다. 따라서 추후 건강증진 사업운영 시 참여자의 건강증진 행위실천을 돕기 위한 물품을 지원하고 파트너십을 구축(모임, 동아리) 하는 등 주민참여 향상을 위한 다양한 정책전략이 필요하다.

콘텐츠 디자인교육을 위한 의사 결정 트리 활용 방법과 사례연구 (Method and Case Study of Decision Tree for Content Design Education)

  • 김성곤
    • 문화기술의 융합
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    • 제5권4호
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    • pp.283-288
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    • 2019
  • 수강생들의 정보와 경험 부족을 극복하기 위해, 의사 결정 트리를 활용한 콘텐츠 기획 트리를 개발하였다. 콘텐츠 기획 트리는 수강생들이 개발할 주제와 스토리를 선택하는 나무 몸통 생성단계, 해당 스토리를 바탕으로 개발 가능한 형태 '범주'를 선택하는 부모 가지 생성단계, 해당 콘텐츠를 효과적으로 제작하는 흥미 '효과'를 선택하는 자식가지 생성단계 그리고 시각화할 멀티미디어 표현 '요소'를 선택하는 잎사귀 생성단계로 구성된다. 교육 모델은 게임기획 디자인과 정보시각화 강의에 적용되었고, 각 강의에서 사용된 범주, 효과 그리고 요소의 예를 사례로 제시한다. 교육 모델은 145개 팀 프로젝트에 사용되었고, 단계별 학습 프로세스로 효율성을 확인하였다.