• Title/Summary/Keyword: project team

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Synthesis and Conformation of Novel 3'-Branched Threosyl-5'-Deoxyphosphonic Acid Nucleoside Analogues

  • Shen, Guang Huan;Kang, Lien;Kim, Eun-Ae;Lee, Won-Jae;Hong, Joon-Hee
    • Bulletin of the Korean Chemical Society
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    • v.33 no.8
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    • pp.2574-2580
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    • 2012
  • The discovery that threosyl phosphonate nucleoside (PMDTA, $EC_{50}=2.53{\mu}M$) is a potent anti-HIV agent has led to the synthesis and biological evaluation of 5'-deoxy versions of threosyl phosphonate nucleosides. In the present study, (E)-3'-phosphonoalkenyl and 3'-phosphonoalkyl nucleoside analogues 13, 16, 20 and 23 were synthesized from acetol and tested for anti-HIV activity and cytotoxicity. The adenine analogue 16 was found to exhibit moderate in vitro anti-HIV-1 activity ($EC_{50}=22.2{\mu}M$).

Nano phosphors for PDP RGB and their PL characteristics

  • Yang, Choong-Jin;Choi, S.D.;Park, E.B.;Park, J.I.;Lee, Y.J.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08b
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    • pp.1646-1649
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    • 2007
  • RF plasma and aerosol nano process were developedfor a volume production of nanoscale phosphors. R, G, and B PDP phosphors were synthesized and the characteristics were optimized through the proprietary power treatments. PL intensities were confirmed to be enhanced up to 70% of that of present commercial phosphors.

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Formulation and In vitro Evaluation of Transdermal Drug Delivery System for Galantamine

  • Hossain, Md. Kamal;Subedi, Robhash Kusam;Chun, Myung-Kwan;Kim, Eun-Jung;Moon, Hwan-Shik;Choi, Hoo-Kyun
    • Journal of Pharmaceutical Investigation
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    • v.41 no.1
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    • pp.1-7
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    • 2011
  • The effects of different formulation variables including pressure sensitive adhesive (PSA), permeation enhancer, thickness of the matrix and loading amount of drug on the transdermal absorption of galantamine were investigated across the hairless mouse skin. The permeation profile of galantamine was different depending on the types of PSA, loading amount of drug, thickness of the matrix and type of enhancer used. Highest flux of galantamine was obtained from acrylic PSA but crystals were formed in the patch within 72 h. Among the PSAs screened, crystal formation was not observed only in the patches formulated in Styrene Butadiene Styrene (SBS) matrix. Permeation rate increased linearly as the concentration of galantamine in SBS matrix increased from 2.5 to 15% w/w. Among the enhancers screened, Brij$^{(R)}$ 30 provided highest flux of galantamine. Matrix thickness of 80 ${\mu}m$ was optimum for maintaining adhesiveness as well as consistently delivering galantamine for longer period of time.

Study of a Computational Simulation Model for Analyzing Species Interactions in Bio-ecosystem (생명체 간의 상호작용 분석을 위한 계산 시뮬레이션 모델 연구)

  • Bae, Kyungmin;Yeo, Eunji;Kim, Chul-soo;Ma, Jin-hyun;Chi, Jeong-gyu;Kim, Hyung-seon;Lee, Jeong-hyeong;Lim, Hyo-sang
    • Proceedings of the Korea Information Processing Society Conference
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    • 2014.04a
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    • pp.536-539
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    • 2014
  • 본 논문에서는 생명체 간의 상호작용으로 형성된 안정된 생태계의 요인을 분석할 수 있는 계산 시뮬레이션 모델을 제안한다. 그리고, 실제 시뮬레이션 프로그램을 개발하고 이를 통해 얻은 실험 결과를 제시함으로써, 계산 시뮬레이션 분야와 생명과학 분야의 융합 가능성을 보인다. 제시한 계산 시뮬레이션 모델은 1) 하나의 커다란 생태계로 이루어진 세계, 2) 다수의 작은 생태계로 이루어진 세계, 3) 생태계가 미형성된 세계를 유전 알고리즘을 사용하여 모델링 하였으며, 실험 결과는 2)번 모델이 생태계를 가장 안정적인 상태로 오래 유지하는 결과를 보였다. 이를 통해서 충분한 에너지가 존재하거나 공급되는 환경에서는 생물 밀도가 높으면서 에너지 순환이 빠른, 작은 규모의 생태계가 가장 안정적이라는 생물학적인 결론을 도출할 수 있었다.

Unusual Ultrasonographic Features of Chronic Hypertrophic Pyloric Gastropathy in Two Dogs

  • Rhim, Haerin;Moon, Sohyeon;Lee, Gahyun;Park, Seungjo;Cho, Kyoung-Oh;Choi, Jihye
    • Journal of Veterinary Clinics
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    • v.35 no.6
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    • pp.302-307
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    • 2018
  • This report describes the unusual ultrasonography features of chronic hypertrophic pyloric gastropathy in two dogs - a 12-year-old neutered male Pekingese (case 1) and an 11-year-old spayed female Shih Tzu (case 2) - with chronic vomiting and weight loss. Chronic hypertrophic pyloric gastropathy can be observed as the focal thickening of the pyloric wall with normal layers on ultrasonography images. However, in case 1, gastric neoplasia could not be ruled out because of the presence of regional lymph node enlargement; in case 2, an intussusception was tentatively diagnosed because of a mass within the pylorus, which appeared to be connected to the descending duodenum on the longitudinal image. In both cases, focally thickened pyloric walls were demonstrated through exploratory laparotomy, and the histopathological diagnosis of chronic hypertrophic pyloric gastropathy was made. Ultrasonography is useful for imaging the gastrointestinal tract, and the typical ultrasonographic features of chronic hypertrophic pyloric gastropathy have been reported. However, the possibility, that chronic hypertrophic pyloric gastropathy can present unusual ultrasonographic findings similar to those of tumors or intussusception, should also be considered.

Fabrication and Characterization of Carbon Nanotube Field Emission Display for HD-TV Applications

  • Lee, Chun-Gyoo;Chi, Eung-Joon;Hwang, Sung-Yeon;Lee, Sang-Jo;Lee, Sang-Jin;Yoon, Tae-Ill;Lee, Byong-Gon;Nam, Joong-Woo;Ryu, Mee-Ae;Han, Ho-Su;Jin, Sung-Hwan;Ahn, Sang-Hyuck;Seo, Hyoung-Cheol;Choi, Jong-Sik;Oh, Tae-Sik;Kang, Sung-Kee;Kim, Jong-Min;Kim, Jung-Woo;Park, Young-Jun;Han, In-Taek;Jin, Yong-Wan
    • 한국정보디스플레이학회:학술대회논문집
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    • 2003.07a
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    • pp.191-192
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    • 2003
  • For the CNT-FED to be cost-effective, many efforts for the lower voltage operation have been made in the under-gate cathode structure. In this study, the effects of the frit proportion in the CNT paste, cathode electrode width, CNT-to-counter electrode gap, and the CNT length in the cathode structure were examined.

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The effects of the online team project-based learning on problem solving ability, cooperative self efficacy and cooperative self regulation in students of department of physical therapy

  • Kim, Jung Hee;Lee, Woo Hyung
    • Journal of Korean Physical Therapy Science
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    • v.28 no.3
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    • pp.1-10
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    • 2021
  • Background: The purpose of this study is to investigate the effect of the online team project based learning on problem-solving, cooperative self-efficacy, and cooperative self-regulation of college students. Design: Single group pre-post design. Methods: The online team project based learning was conducted for a total of 92 college students for 8 weeks. A survey was conducted on problem-solving ability, cooperative self-efficacy, and cooperative self-regulation. In the online team project-based class, two projects were performed. It consists of video lectures and real-time video conferencing. Through the real-time video conference, the project was carried out based on discussion among learners and feedback was provided. Results: There was a significant difference in the change in problem-solving ability compared to before learning (p<0.05). As a result of the evaluation of cooperative self-efficacy, there was a significant difference (p<0.05). There was a significant differences in cooperative self-regulation compared to before learning (p<0.05). Conclusion: The online team project-based learning are effective in improving learners' problem-solving ability, cooperative self-efficacy, and cooperative self-regulation.

The Impacts of Project Governance, Agency Conflicts on the Project Success : From the Perspective of Agency Theory (프로젝트 거버넌스가 대리인 갈등 및 프로젝트 성공에 미치는 영향 : 대리인 이론 관점)

  • Jeong, Eun-Joo;Kim, Bo-Ram;Jeong, Seung-Ryul
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.41 no.3
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    • pp.11-20
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    • 2018
  • Recently companies have increased the new projects to improve and innovate the business process in order to adopt the advanced technologies such as IoT (Internet of Things), Big Data Analysis, Cloud Computing, mobile and artificial intelligence technologies for sustainable competitive advantages under rapid technological and socioeconomic external environmental changes. However, there are obstacles to achieve the project goals, corporate's strategy and objectives due to various kind of risks based on characteristics of projects and conflicts of stakeholders participated on projects. Hence, the solutions are required to resolve the various kind of risks and conflicts of stakeholders. The objectives of this study are to investigate the impact of the project governance, agency conflicts on the project success based on agency theory by using the statistical hypothesis testing the relationship among those variables. As a result of hypothesis testing, we could find that the project governance impacts positively on project success and negatively on the agency conflicts. Further, the agency conflicts impacts negatively on the project success. Finally, we could find that the agency conflicts such as goal conflict, different risk attitude and information asymmetry between project manager and team members impact negatively on the project success. Meanwhile, the project governance impact positively on the project success, negatively impact on the agency conflicts such as goal conflict, different risk attitude and information asymmetry between project manager and project team members. In order to increase the project success rate, the project governance institutions such as PGB (Project Governance Board), EPMO (Enterprise Project Management Office), PSC (Project Steering Committee) are needed to prevent or reduce the agency conflicts between project manager and team members.

A Case Study on Resident Participative Primary Design of Integrated Rural Development Project with Master Planner - Onui Area in Hong Seong - (총괄계획가 시범사업에서 주민참여 기본계획 사례연구 - 홍성 오누이권역을 대상으로 -)

  • Jung, Nam Su
    • Journal of Korean Society of Rural Planning
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    • v.21 no.4
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    • pp.167-175
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    • 2015
  • The aim of this study is to establish resident-participative primary design of integrated rural development project with master planner by setting principals of open competition and transparent decision-making about village-to-village or business-to-business unit enterprise in Onui area, Hong-seong Gun. For effective processing, software projects such as residents education and rural landscape planning are simultaneously conducted for enhancing project understanding and comprehensive development plan including related post project. Above all, competition teams for individual project were organized to establish the resident-participative primary design using survey tables of residents demand. In 6 months resident-participative processing of primary design, continuous education and visiting to advanced area are conducted in team unit. Strengthened ability of team unit can be used in management and maintenance after project development. To do this, residents with the same opinions gathered as one competition team and identified business plans such as village asset, business location, size, program, and method for land securing. Favorable decision-making process by residents who are audience in project presentation of competition team has conducted. After selecting competition teams, continuos consulting are operated for establishing operation and management for developed or remodeled facilities through repetitive education and visiting advanced area. In this process, unit project suggested by competition team are completed. Preliminary selection was conducted by experts who were entrusted by residents. After residents agreement of project main stream such as major facilities and location, final detailed cost of projects are work out. Suggested process in this study which choose the final project by residents would improve residents' voluntary participation in integrated rural development project through open competition in establishing primary design.