• Title/Summary/Keyword: profile modifying

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Genetics and Breeding for Modified Fatty Acid Profile in Soybean Seed Oil

  • Lee, Jeong-Dong;Bilyeu, Kristin D.;Shannon, James Grover
    • Journal of Crop Science and Biotechnology
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    • v.10 no.4
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    • pp.201-210
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    • 2007
  • Soybean [Glycine max(L.) Merr.] oil is versatile and used in many products. Modifying the fatty acid profile would make soy oil more functional in food and other products. The ideal oil with the most end uses would have saturates(palmitic + stearic acids) reduced from 15 to < 7%, oleic acid increased from 23 to > 55%, and linolenic acid reduced from 8 to < 3%. Reduced palmitic acid(16:0) is conditioned by three or more recessive alleles at the Fap locus. QTLs for reduced palmitic acid have mapped to linkage groups(LGs) A1, A2, B2, H, J, and L. Genes at the Fad locus control oleic acid content(18:1). Six QTLs($R^2$=4-25%) for increased 18:1 in N00-3350(50 to 60% 18:1) explained four to 25% of the phenotypic variation. M23, a Japanese mutant line with 40 to 50% 18:1 is controlled by a single recessive gene, ol. A candidate gene for FAD2-1A can be used in marker-assisted breeding for high 18:1 from M23. Low linolenic acid(18:3) is desirable in soy oil to reduce hydrogenation and trans-fat accumulation. Three independent recessive genes affecting omega-3 fatty acid desaturase enzyme activity are responsible for the lower 18:3 content in soybeans. Linolenic acid can be reduced from 8 to about 4, 2, and 1% from copies of one, two, or three genes, respectively. Using a candidate gene approach perfect markers for three microsomal omega-3 desaturase genes have been characterized and can readily be used in for marker assisted selection in breeding for low 18:3.

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Damage Assessment of Free-fall Dropped Object on Sub-seabed in Offshore Operation

  • Won, Jonghwa;Kim, Youngho;Park, Jong-Sik;Kang, Hyo-dong;Joo, YoungSeok;Ryu, Mincheol
    • Journal of Advanced Research in Ocean Engineering
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    • v.1 no.4
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    • pp.198-210
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    • 2015
  • This paper presents the damage assessment of a free-fall dropped object on the seabed. The damage to a dropped object totally depends on the relationship between the impact energy and the soil strength at the mudline. In this study, unexpected dropping scenarios were first assumed by varying the relevant range of the impact velocity, structure geometry at the moment of impact, and soil strength profile along the penetration depth. Theoretical damage assessments were then undertaken for a free-fall dropping event with a fixed final embedment depth for the structure. This paper also describes the results of a three-dimensional large deformation finite element analysis undertaken for the purpose of validation. The analyses were carried out using the coupled Eulerian-Lagrangian approach, modifying the simple elastic-perfectly plastic Tresca soil model. The validation exercises for each dropping scenario showed good agreement, and the present numerical approach was capable of predicting the behavior of a free-fall dropped object.

Employing Al Etch Stop Layer for Nb-based SNS Josephson Junction Fabrication Process (Al 식각정지층을 이용한 Nb-based SNS 조셉슨 접합의 제조공정)

  • Choi, J.S.;Park, J.H.;Song, W.;Chong, Y.
    • Progress in Superconductivity
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    • v.12 no.2
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    • pp.114-117
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    • 2011
  • We report our efforts on the development of Nb-based non-hysteretic Josephson junction fabrication process for quantu device applications. By adopting and modifying the existing Nb-aluminum oxide tunnel junction process, we develop a process for non-hysteretic Josephson junction circuits using metal-silicide as metallic barrier material. We use sputter deposition of Nb and $MoSi_2$, PECVD deposition of silicon oxide as insulator material, and ICP-RIE for metal and oxide etch. The advantage of the metal-silicide barrier in the Nb junction process is that it can be etched in $SF_6$ RIE together with Nb electrode. In order to define a junction area precisely and uniformly, end-point detection for the RIE process is critical. In this paper, we employed thin Al layer for the etch stop, and optimized the etch condition. We have successfully demonstrated that the etch stop properties of the inserted Al layer give a uniform etch profile and a precise thickness control of the base electrode in Nb trilayer junctions.

User Reputation computation Method Based on Implicit Ratings on Social Media

  • Bok, Kyoungsoo;Yun, Jinkyung;Kim, Yeonwoo;Lim, Jongtae;Yoo, Jaesoo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.3
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    • pp.1570-1594
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    • 2017
  • Social network services have recently changed from environments for simply building connections among users to open platforms for generating and sharing various forms of information. Existing user reputation computation methods are inadequate for determining the trust in users on social media where explicit ratings are rare, because they determine the trust in users based on user profile, explicit relations, and explicit ratings. To solve this limitation of previous research, we propose a user reputation computation method suitable for the social media environment by incorporating implicit as well as explicit ratings. Reliable user reputation is estimated by identifying malicious information raters, modifying explicit ratings, and applying them to user reputation scores. The proposed method incorporates implicit ratings into user reputation estimation by differentiating positive and negative implicit ratings. Moreover, the method generates user reputation scores for individual categories to determine a given user's expertise, and incorporates the number of users who participated in rating to determine a given user's influence. This allows reputation scores to be generated also for users who have received no explicit ratings, and, thereby, is more suitable for social media. In addition, based on the user reputation scores, malicious information providers can be identified.

A Mechanism for Protecting a Mobile Agent's Communication (이동 에이전트의 통신 보안 메카니즘)

  • 임동주;오창윤;배상현
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.2
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    • pp.435-442
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    • 2000
  • In the world of mobile agents, security aspects are extensively being discussed, with strong emphasis on how agents can be protected against malicious hosts and vice versa. This paper discusses methods for protecting an agent's route information from being misused by sites on route interested in gaining insight into the profile of the agent's owner or in obstructing the owner's original goal. Our methods provide visited sites with just a minimum of route information, but on the other hand allow sites to detect modifying attacks of preceding sites. Though, under noncolluding attacks, all methods presented provide a similar level of protection, the performance and the points of time differ when an attack can be detected.

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CPW-Fed π-Shaped Antenna for Wideband (CPW급전 광대역 파이형 안테나)

  • Kang, Young-Man;Ceong, Hyi-Thaek;Rhee, Seung-Yeop
    • The Journal of the Korea institute of electronic communication sciences
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    • v.13 no.2
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    • pp.291-298
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    • 2018
  • In this paper, we propose an antenna that improves narrow band characteristics which is a disadvantage of inverted-F type antenna and utilizes the structural advantages of small size and low profile by modifying the inverted-F type antenna structure and applying CPW feeding method. Experimental results show that the broadband characteristic of about 40% at the center frequency of 3 GHz is seen, and it is found that the narrow band characteristic which is a disadvantage of the conventional inverted F antenna can be improved. The radiation pattern showed almost omnidirectional characteristics and the maximum gain was about 2.0dBi.

Controlled Release of Gentamicin Sulfate from Poly(3-hydroxybu-tyrate-co-3-hydroxyvalerate) Wafers for the Treatment of Osteomyelitis

  • Gilson Khang;Park, Hak-Soo;John M. Rhee;Yoon, Sung-Chul;Cho, Jin-Cheol;Lee, Hai-Bang
    • Macromolecular Research
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    • v.8 no.6
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    • pp.253-260
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    • 2000
  • Biodegradable wafers were prepared with poly (hydroxybutyrate-co-hydroxyvalerate) (PHBV;5, 10, and 15 mole% for 3-hydroxyvalerate) by simple heat pressing method for the sustained release of antibiotic agent, gentamicin sulfate (GS) to investigate the possibility of the treatment for osteomyelitis. The effects of hydroxyvalerate (HV) content, thickness of wafers, various types of additives such as sodium dodecyl sulfate (SDS), microcrystalline cellulose, polyvinylpyrrolidone, and hydroxypropylcellulose (HPC), and different initial drug loading ratio on the release profile have been investigated. In vitro release studies showed that different release patterns and rates could be achieved by simply modifying factors in the preparation conditions. PHBV wafers with 3 mm thickness, 10% of GS initial loading, 15% of HV content and addition of 5% of SDS and HPC were free from initial burst and a near-zero-order sustained release was observed for over 30 days. It might be suggested that the mechanisms of G5 release may be more predominant simple dissolution and diffusion of GS than erosion of PHBV in our system.

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Improved Margin of Absorber Pattern Sidewall Angle Using Phase Shifting Extreme Ultraviolet Mask (위상변위 극자외선 마스크의 흡수체 패턴의 기울기에 대한 오차허용도 향상)

  • Jang, Yong Ju;Kim, Jung Sik;Hong, Seongchul;Ahn, Jinho
    • Journal of the Semiconductor & Display Technology
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    • v.15 no.2
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    • pp.32-37
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    • 2016
  • Sidewall angle (SWA) of an absorber stack in extreme ultraviolet lithography mask is considered to be $90^{\circ}$ ideally, however, it is difficult to obtain $90^{\circ}$ SWA because absorber profile is changed by complicated etching process. As the imaging performance of the mask can be varied with this SWA of the absorber stack, more complicated optical proximity correction is required to compensate for the variation of imaging performance. In this study, phase shift mask (PSM) is suggested to reduce the variation of imaging performance due to SWA change by modifying mask material and structure. Variations of imaging performance and lithography process margin depending on SWA were evaluated through aerial image and developed resist simulations to confirm the advantages of PSM over the binary intensity mask (BIM). The results show that the variations of normalized image log slope and critical dimension bias depending on SWA are reduced with PSM compared to BIM. Process margin for exposure dose and focus was also improved with PSM.

Cardiovascular Diseases and Panax ginseng: A Review on Molecular Mechanisms and Medical Applications

  • Kim, Jong-Hoon
    • Journal of Ginseng Research
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    • v.36 no.1
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    • pp.16-26
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    • 2012
  • Ginseng is one of the most widely used herbal medicines and is reported to have a wide range of therapeutic and pharmacological applications. Ginseng may also be potentially valuable in treating cardiovascular diseases. Research concerning cardiovascular disease is focusing on purified individual ginsenoside constituents of ginseng to reveal specific mechanisms instead of using whole ginseng extracts. The most commonly studied ginsenosides are $Rb_1$, $Rg_1$, $Rg_3$, $Rh_1$, Re, and Rd. The molecular mechanisms and medical applications of ginsenosides in the treatment of cardiovascular disease have attracted much attention and been the subject of numerous publications. Here, we review the current literature on the myriad pharmacological functions and the potential benefits of ginseng in this area. In vitro investigations using cell cultures and in vivo animal models have indicated ginseng's potential cardiovascular benefits through diverse mechanisms that include antioxidation, modifying vasomotor function, reducing platelet adhesion, influencing ion channels, altering autonomic neurotransmitters release, and improving lipid profiles. Some 40 ginsenosides have been identified. Each may have different effects in pharmacology and mechanisms due to their different chemical structures. This review also summarizes results of relevant clinical trials regarding the cardiovascular effects of ginseng, particularly in the management of hypertension and improving cardiovascular function.

The Determinants of a Health Promoting Lifestyle in High school students (고등학생의 건강증진 생활양식과 관련 요인)

  • Hong, Woi-Hyun;Kim, Chung-Nam
    • Research in Community and Public Health Nursing
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    • v.10 no.2
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    • pp.330-346
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    • 1999
  • This descriptive correlational study was conducted to identify the variables related to a health promoting lifestyle in high school students. 304 high school students and 189 vocational high school students living in Taegu city were selected by a convenience sampling method. The data were collected by self-reported questionnaires from August 24 to September 4, 1998. Pender and others' Health Promoting Lifestyle Profile, Shere et al's. Self-Efficacy scale, Wallston et al.'s Internal Health Locus of Control scale, Wares' Health self rating scale and Cohen & Hoberman's Social support scale were used. The data were analyzed by using descriptive statistics, Pearson correlation coefficient, t-test, MANOVA, ANOVA. Tukey verification and Stepwise multiple regression with an SAS program. The results of this study were as follows: 1. The average score of a health promoting lifestyle performance was 2.38(SD=.36) of a 4 point scale .Self-actualization (mean = 2.80. SD = .60). interpersonal support(mean = 2.73, SD=.47), health responsibility (mean=1.53, SD=.47), nutrition(mean=2.64, SD=.63), exercise(mean=2.71. SD=.72) and stress management(mean=2.37, SD=.58) were also analyzed. 2. The combination of self-efficacy, social-support, internal health locus of control. father's educational level and perceived health status explained 37.97% of the variance in health promoting lifestyles. 3. A Health promoting lifestyle showed significant positive correlations with self efficacy(r=.5173. p=.0011), perceived health status(r=.254, p=.001) and internal health locus of control(r=.321. p=.001). 4. According to sex(t=7.38. p=.006). economic state(F=6.62, p=.00l), Father's educational level(F=4.25, p=.005), mother's educational level(F=6.94. p=.000l), the grade of educational performance(F=3.74, p=.024), sleeping hours(F=3.47. p=.032) and social support(F=40.76, p=.0001). there were significant differences and modifying factors in health promoting lifestyles. On the basis of the above findings. self-efficacy in cognitive factors, and social support in modifying factors were identified as the variables which explained most of Pender's health-promotion model. Nursing strategies enhancing self-efficacy and social support which have a more significant effect on health promoting lifestyles should be developed. Further research is required to find out the factors influencing health pormoting lifestyle of high school students.

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