• Nutrition Research and Practice
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• v.9 no.3
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• pp.242-248
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• 2015

BACKGROUND/OBJECTIVES: Feeding in infancy is the most significant determinant of the intestinal microbiota in early life. The aim of this study was to determine the gut microbiota of Korean infants and compare the microbiota obtained between breast-fed and formula-fed Korean infants. SUBJECTS/METHODS: We analyzed the microbial communities in fecal samples collected from twenty 4-week old Korean (ten samples in each breast-fed or formula-fed) infants using pyrosequencing. RESULTS: The fecal microbiota of the 4-week-old Korean infants consisted of the three phyla Actinobacteria, Firmicutes, and Proteobacteria. In addition, five species, including Bifidocbacterium longum, Streptococcus salivarius, Strepotococcus lactarius, Streptococcus pseudopneumoniae, and Lactobacillus gasseri were common commensal intestinal microbiota in all infants. The predominant intestinal microbiota in the breast-fed infants (BFI) included the phylum Actinobacteria (average 70.55%), family Bifidobacteriacea (70.12%), genus Bifidobacterium (70.03%) and species Bifidobacterium longum (69.96%). In the microbiota from the formula-fed infants (FFI), the proportion of the phylum Actinobacteria (40.68%) was less, whereas the proportions of Firmicutes (45.38%) and Proteobacteria (13.85%) as well as the diversity of each taxonomic level were greater, compared to those of the BFI. The probiotic species found in the 4-week-old Korean infants were Bifidobacterium longum, Streptococcus salivarius, and Lactobacillus gasseri. These probiotic species accounted for 93.81% of the microbiota from the BFI, while only 63.80% of the microbiota from the FFI. In particular, B. longum was more abundant in BFI (69.96%) than in FFI (34.17%). CONCLUSIONS: Breast milk supports the growth of B. longum and inhibits others. To the best of our knowledge, this study was the first attempt to analyze the gut microbiota of healthy Korean infants according to the feeding type using pyrosequencing. Our data can be used as a basis for further studies to investigate the development of intestinal microbiota with aging and disease status.

• Journal of the Korean Institute of Landscape Architecture
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• v.38 no.4
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• pp.1-10
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• 2010

The scientific verification of the physiological and psychological effects that result from interaction with green plants would not only provide objective knowledge on the psychological effect of green but would also establish useful grounds for the creation of green spaces that consider human emotions. The present study measured the cerebral activity(cerebral blood flow) and the autonomic nervous system activity (blood pressure, pulse rate, amylase) of fifteen Korean male subjects as they inhaled the natural scent diffused by pine needles. Impression and mood state evaluations of the reactions to the pine scent were carried out using the SD method and POMS. Cerebral activity was observed to be significantly activated in the feeling, judgment, and motor areas of the frontal lobe, as well as the memory area in the temporal lobe. Verbal evaluations by the SD method and POMS indicated a pine scent left natural but stimulated and active impressions, provided vigor, and also reduced confusion. The autonomic nervous system activities, however, showed no significant differences. These findings verified scientifically that a pine scent vitalizes humans both physiologically and psychologically. These results could be useful as fundamental data for the design of green spaces that consider human emotional aspects.

• Journal of Korea Water Resources Association
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• v.41 no.9
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• pp.929-941
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• 2008

The objectives of this study are to propose a system for combined use of a hydrologic and a hydraulic model for urban flood forecast model and to evaluate the system on the $300km^2$ Jungrang urban watershed area, which is relatively large area as an urban watershed and consequently composed of very complex drainage pipes and streams with different land uses. In this study, SWMM for hydrologic model and HEC-RAS for hydraulic model are used and the study area is divided into 25 subbasins. The SWMM model is used for sewer drainage analysis within each subbasin, while HEC-RAS for unstready flow analysis in the channel streams. Also, this study develops a GUI system composed of mean areal precipitation input component, hydrologic runoff analysis component, stream channel routing component, and graphical representation of model output. The proposed system was calibrated for the model parameters and verified for the model applicability by using the observation data. The correlation coefficients between simulated and observed flows at the 2 important locations were ranged on 0.83-0.98, while the coefficients of model efficiency on 0.60-0.92 for the verification periods. This study also provided the possibilities of manhole overflows and channel bank inundation through the calculated water profile of longitudinal and channel sections, respectively. It can be concluded that the proposed system can be used as a surface runoff and channel routing models for urban flood forecast over the large watershed area.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.9
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• pp.482-491
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• 2018

This study intended to identify different level of teacher-efficacy, perception of principals' leadership and peer collaboration as it pertains to a teachers' job stress and job satisfaction in Elementary school. Samples include 1,031 teachers in elementary school from Korean Children & Youth Panel Survey(KCYPS) and data were analyzed using Latent Class Analysis(LCA) to identify different patterns of teacher-efficacy and perception of principals' leadership and peer collaboration. Multivariate analysis of variance were employed to identify the influence of predictors for classification of teachers' job stress and job satisfaction among latent classes. The study found three latent classes at risk class, middle-level adaptive class, and adaptive class and results showed that each distinctive class can be identified by some of predictors. Teachers at adaptive class showed higher teacher-efficacy and positive perception of principals' leadership and peer collaboration than teachers at risk and middle-level adaptive class. Also, teachers at adaptive class showed lower job stress and higher job satisfaction than teachers at two other classes. The study suggests that help teachers based on personal profile are effective rather teacher-efficacy and perception of principals' leadership and peer collaboration.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.3
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• pp.161-166
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• 2017

In recent times, many people have problems of nutritional imbalance; lack or surplus intake of a specific nutrient despite the variety of available foods. Accordingly, the interest in health and diet issues has increased leading to the emergence of various mobile applications. However, most mobile applications only record the user's diet history and show simple statistics and usually provide only general information for healthy diet. It is necessary for users interested in healthy eating to be provided recommendation services reflecting their food interest and providing customized information. Hence, we propose a menu recommendation method which includes calculating the recommended calorie amount based on the user's physical and activity profile to assign to each food group a substitution unit. In addition, our method also analyzes the user's food preferences using food intake history. Thus it satisfies recommended intake unit for each food group by exchanging the user's preferred foods. Also, the excellence of our proposed algorithm is demonstrated through the calculation of precision, recall, health index and the harmonic average of the 3 aforementioned measures. We compare it to another method which considers user's interest and recommended substitution unit. The proposed method provides menu recommendation reflecting interest and personalized health status by which user can improve and maintain a healthy dietary habit.

• Journal of the Korean Geosynthetics Society
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• v.13 no.3
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• pp.1-10
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• 2014

Several types of methods such as resistivity survey, ground penetration radar, etc are used for detection of levee leakage and according to the river design guidelines detection of levee leakage is performed by measuring the hydraulic conductivity of levee soil. But, the former can not verify the leakage point and degree of saturation, the latter is an after treatment method. Movable sensor, which is a high-tech TDR system developed since 2000, can obtain directly the dielectric constant profile covering the whole depth of levee. In this study, laboratory and field model experiments were carried out using movable TDR sensor in order to evaluate the applicability as detection system of levee leakage, As the result, movable TDR system has proven to be 3 times more sensitive to water contents than dry unit weight, and the results conclude that the dielectric constant, water contents and density of the ground proved to have a correlation among them, and the dielectric constant is expected to be a basic data on detection of levee leakage.

• International Journal of Highway Engineering
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• v.3 no.2 s.8
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• pp.131-140
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• 2001

Concrete pavement of Jungbu Expressway composed of CRCP(Continuously Reinforced Concrete Pavement) and JCP(Jointed Concrete Pavement). The CRCP was firstly constructed and applied to new expressway in Korea. It is a good source of the study to analyze the performance of CRCP and JCP because it experiences same amount of traffic and environmental loading. Up to the present, condition survey has conducted several times during 13 years but roughness measurement has not been carefully conducted. Through comparisons among several types of pavement(CRCP, JCP, Asphalt) by roughness, CRCP is superior to JCP. In addition, connected sections in the highway such as bridges and tunnels that have higher IRI values, about 5mm/m, than normal sections should be considered appropriated maintenance such as diamond grinding. The relationship between IRI and distresses carried out by Korea Highway Cooperation in 1999 skewed that the number of crack is related to IRI value in JCP, while other distresses of JCP and CRCP are not shown clearly. The comparison study with IRI values between Jungbu Expressway and GPS-3(JCP) and GPS-5(CRCP) of LTPP data also showed that roughness of Jungbu Expressway is not inferior to that of the state. Some of section showed larger values of IRI are linked with under-9round structures for passages and drainages. The overall performance considering only roughness, the CRCP is also superior to JCP in sections with under-ground tunnels.

• 한국해양학회지
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• v.3 no.1
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• pp.16-25
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• 1968

This study was undertaken to assess the annual cycle of primary production and plant pigments in a downstream of the Han River. Measurements were carried out at three week intervals during April 1966 and March 1967, and ancillary data include water temperature, transparency, pH, dissolved oxygen and phytoplankton cell number. The seasonal cycle in water temperature profile shows the hihgest in the end of August with 27$^{\circ}C$, lowest in the middle of February with 0.2$^{\circ}C$. The transparency with Secchi disk reading varied from a maximum 4.0m in fall and a minimum 0.5m or less in early spring and flood season of summer. The pH of the river water varied from 6.5 to 7.3, averaged 6.91 in the surface water and 6.98 in the bottom water, showed little seasonalvariability. The dissolved oxygen in the surface water ranged from 5.93-9.64ml/L, while in the bottom water it ranged from 5.54-9.72 ml/L, and the oxygen saturation never fall below 94%. None thermal, the distribution of pH and content of oxygen, stratifications occurred. An apparent seasonal cycle of primary productivity was observed with remarkably high levels in the spring and fall, the lowest level in the winter. The range of net carbon assimilations showed 3.1-112.6 mgC/㎥/day or 15-427 mgC/㎡/day in spring, 37.0-271.2 mgC/㎥/day or 115-329 mgC/㎡/day in summer, 27.2-168.0 mgC/㎥ /day or 139-415 mgC/㎡/day in fall and 0.5-10.9 mgC/㎥/day or 5-19 mg/㎡/day in winter, respectively. Amount of chlorophyll ${\alpha}$ ranged from a minimum concentration of 0.2-0.3 mg/㎥ in the middle of February and a maximum 4.1-6.7 mg/㎥ in the middle of June. A general increase trend in chlorophyll ${\alpha}$ concentration was noted with increase of the river water temperature.

• Toxicological Research
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• v.34 no.3
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• pp.221-229
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• 2018

Tenofovir nanoparticles are novel therapeutic intervention in human immunodeficiency virus (HIV) infection reaching the virus in their sanctuary sites. However, there has been no systemic toxicity testing of this formulation despite global concerns on the safety of nano drugs. Therefore, this study was designed to investigate the toxicity of Tenofovir nanoparticle (NTDF) on the liver and kidney using an animal model. Fifteen adult male Sprague-Dawley (SD) rats maintained at the animal house of the biomedical resources unit of the University of KwaZulu-Natal were weighed and divided into three groups. Control animals (A) were administered with normal saline (NS). The therapeutic doses of Tenofovir (TDF) and nanoparticles of Tenofovir (NTDF) were administered to group B and C and observed for signs of stress for four weeks after which animals were weighed and sacrificed. Liver and kidney were removed and fixed in formal saline, processed and stained using H/E, PAS and MT stains for light microscopy. Serum was obtained for renal function test (RFT) and liver function test (LFT). Cellular measurements and capturing were done using ImageJ and Leica software 2.0. Data were analysed using graph pad 6, p values < 0.05 were significant. We observed no signs of behavioural toxicity and no mortality during this study, however, in the kidneys, we reported mild morphological perturbations widening of Bowman's space, and vacuolations in glomerulus and tubules of TDF and NTDF animals. Also, there was a significant elevation of glycogen deposition in NTDF and TDF animals when compared with control. In the liver, there were mild histological changes with widening of sinusoidal spaces, vacuolations in hepatocytes and elevation of glycogen deposition in TDF and NTDF administered animals. In addition to this, there were no significant differences in stereological measurements and cell count, LFT, RFT, weight changes and organo-somatic index between treatment groups and control. In conclusion, NTDF and TDF in therapeutic doses can lead to mild hepatic and renal histological damage. Further studies are needed to understand the precise genetic mechanism.

• Journal of Life Science
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• v.19 no.12
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• pp.1851-1854
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• 2009

This study correlated changes in the plasma levels of estradiol-$17{\beta}$ (E2) with changes in the gonadosomatic index (GSI) and ovarian development during the annual reproductive cycle of the pike eel Muraenesox cinereus, collected at the Tongyung coast region. Ovarian maturity was classified based on histological observations; the perinucleolus stage (November to February), the oil droplet stage (March to April), the early vitellogenic stage (April to May) and the late vitellogenic stage (June to October). Seasonal changes in the GSI were correlated with water temperature and reflected the degree of ovarian maturity. Plasma E2 levels were correlated with changes in the GSI, which increased from April to a peak in July, and the levels remained comparatively high until October. These data indicated that changes in the GSI and plasma E2 levels are correlated with the annual ovarian activity of the pike eel. In this study, however, female pike eels were not collected during the spawning stage. Therefore, spawning of this species seemed to be closely related to its migration toward the deep sea of offshore.