Much progress has been made in understanding the subcellular events of the human lung injuries after acute exposure to environmental air pollutants. Host of those events represent oxidative damages mediated by reactive oxygen species such as superoxide, hydrogen peroxide, and the hydroxy, free radical. Recently, nitric oxide (NO) was found to be endogenously produced by endothelial cells and cells of the reticulo-endothelial system as endothelialderived relaxation factor (EDRF) which is a vasoactive and neurotransmitter substance. Together with superoxide, NO can form another strong oxidant, peroxonitrite. The relative importance of exogenous sources of $N0/N0_2$ and endogenous production of NO by the EDRF producing enzymes in the oxidative stresses to the heman lung has to be elucidated. The exact events leading to chronic irreversible damage are still yet to be known. From chronic exposure to oxidant gases, progressive epithelial and interstitial damages develop. Type I epithelial cells become thicker and cover a smaller average alveolar surface area while thee II cells proliferate instead. Under acute damages, the extent of loss of the alveolar epithelial cell lining, especially type II cells appears to be a good predictor of the ensuing irreversible damage to alveolar compartment. Interstitial matrix undergo remodeling during chronic exposure with increased collagen fibers and interstitial fibroblasts. However, Inany of these changes can be reversed after cessation of exposure. Among chronic lung injuries, genetic damages and repair responses received particular attention in view of the known increased lung cancer risks from exposure to several air pollutants. Heavy metals from foundry emission, automobile traffics, and total suspended particulate, especially polycystic aromatic hydrocarbons have been positively linked with the development of lung cancer. Asbestos in another air pollutant with known risk of lung cancer and mesothelioma, but asbestos fibers are nonauthentic in most bioassays. Studies using the electron spin resonance spin trapping method show that the presence of iron in asbestos accelerates the production of the hydroxy, radical in vitro. Interactions of these reactive oxygen species with particular cellular components and disruption of cell defense mechanisms still await further studies to elucidate the carcinogenic potential of asbestos fibers of different size and chemical composition. The distribution of inhaled pollutants and the magnitude of their eventual effects on the respiratory tract are determined by pollutant-independent physical factors such as anatomy of the respiratory tract and level and pattern of breathing, as well as by pollutant-specific phyco-chemical factors such as the reactivity, solubility, and diffusivity of the foreign gas in mucus, blood and tissue. Many of these individual factors determining dose can be quantified in vitro. However, mathematical models based on these factors should be validated for its integrity by using data from intact human lungs.
The various environmental problems that we face on today are basically about environmental quality. Since early 1960s affluent material was produced because of remarkable economic growth by many cooperations. However, for the lack of environmental policy, environmental pollutions has been serious. The central government should transfer the producing and consuming structure to environmental affinity through the regulations for developing Korea as a model of environmental nation which takes an active part in global environmental programme and in which the environment and economy are well harmonized. Moreover, the central government should take the lead in prevention of environmental pollution through the direct policies such as strengthening the discharge limit or setting up environmental basic institutions by securing budget for conserving environment. This thesis emphasize on the public institution among many environmental basic institutions for environmental anti-pollution project. It will find the problems with running those institutions, and will suggest the preview of improvement. Also, it is necessary to investigate of variation trend for inflow and pollutant loading to environmental infrastructure as increased of the diffusion rate as established and maintenance of sewer system. The purpose of this study is to investigate for inflow and pollutant loading to environmental infrastructure, and also to provide the method of efficiently maintenance and management. The results obtained were summarized as follows; 1. Survey of actual condition on operation and management of environmental infrastructure was evaluated the propriety of treatment process and problem of plant management. 2. Analysis of pollutant loading contribution for river system of environmental infrastructure with data analysis of water quality measuring network. 3. To investigate on case study for efficiently maintenance and management of environmental infrastructure. The result on this study was provide the method of efficiently maintenance and management with survey for establish and repair of sewer system and survey of actual condition on operation and management of environmental infrastructure in the water area of discharge to Geum River System. Application as guideline for establish and management of environmental infrastructure, and management of Geum River System. Also, application for preliminary data for fulfill-assess of total effluent regulation of water pollution.
This study analyzed visitors' behaviors in the viewpoint of Attraction Power and Holding Power of exhibits on the basis of exhibition layout of real science museums. Through the analysis, the study grasped efficiency of analysis index and exhibition environment elements which might have an effect on planning the exhibition space of a large-scale museum and producing detailed ranges of exhibition. The main indicators used are: 1. Attraction Power: it indicates the relative incidence of people who have stopped in front of an object/exhibit during the exhibition tour. It is calculated by dividing the number of people who stop by the total number of people who have visited the museum or gallery. 2. Holding Power: it measures the average time spent in front of an information/communication element. It is calculated by dividing the average time of stay by the time "necessary" to read an element. As a result of analyzing the exhibition areas of National Science Museum (Daejeon) and National Museum of Emerging Science and Innovation(Tokyo), the Holding Power was found to be relatively lower than the Attracting Power. This means that 3.5 out of 10 visitors stop in front of the exhibit in 6 exhibition areas, and among these, only 1/10 is used when compared to the user required time of the exhibits. In other words, like the method of deriving an analysis index, the stage of viewing can be categorized as Attracting Power and Holding Power, and because the stage from Attracting Power to the stage of Holding Power are strongly linked, it shows that it is not easy to display a meaningful result. Except, the general distribution of Attracting Power was shown to be high from the entrance area of the exhibition hall based on the standard of viewing sequence. Also, the Holding Power became sequentially lower according to the sequence of exhibition viewing and displayed a meaningful interrelationship with the distribution ratio of island exhibits. In the case of island exhibition method, it is less influenced by the movement flow of visitors when compared to the wall type method of exhibition and can be understood as an exhibition method that provides spatial chances enabling stopping and viewing.
The chestnut management standard diagnostic table is developed and would be utilized in order that a manager raising chestnuts checks where the own level of management is and grasps current state of own for the purpose of planning aims and advancing toward a higher level. The developed 'Chestnut management standard diagnostic table' consisted of 3 first classified items, 19 second classified items and 2 product indicator items by the chestnut experts consultative meeting. A survey of 212 farmhouses in 4 major producing area was conducted. Except invalid survey of 53 farmers, 159 farmhouses interviewed were used in analysis. Total score was calculated with sum of each item's score. According to the survey results, average score is 68.0 and Buyeo received the highest score of 69.7 and Suncheon received the lowest score of 61.8 by regional groups. The higher the group in score, the better it is in output per hectare. But the property of 'the ratio of the best products in total products' does not show a statistical correlation. Generally the score of 'management-based evaluation indicator part' and 'management and sale capacity indicator part' in Suncheon was low because of many elderly people. In part of 'manufacturing technology indicator' as Environmentally-Friendly production is progressed in over 70% of four regions, when comes to a disease and insect pest control there are rarely farmhouses having a way of crop dusting.
Queries for tracing tag locations are among the most challenging requirements in RFID based applications, including automated manufacturing, inventory tracking and supply chain management. For efficient query processing, a previous study proposed the index scheme for storing tag objects, based on the moving object index, in 3-dimensional domain with the axes being the tag identifier, the reader identifier, and the time. In a different way of a moving object index, the ranges of coordinates for each domain are quite different so that the distribution of query regions is skewed to the reader identifier domain. Previous indexes for tags, however, do not consider the skewed distribution for query regions. This results in producing many overlaps between index nodes and query regions and then causes the problem of traversing many index nodes. To solve this problem, we propose a new disproportional insertion and split policy of the index for RFID tags which is based on the R*-tree. For efficient insertion of tag data, our method derives the weighted margin for each node by using weights of each axis and margin of nodes. Based the weighted margin, we can choose the subtree and the split method in order to insert tag data with the minimum cost. Proposed insertion method also reduces the cost of region query by reducing overlapped area of query region and MBRs. Our experiments show that the index based on the proposed insertion and split method considerably improves the performance of queries than the index based on the previous methods.
Jung, Da Hee;Chang, Dong Ho;Kim, Yeong Eun;Jeong, Mi Rang;Hahn, Kyu Woong;Kim, Hyong Bai;Park, Kyeong Ryang
Korean Journal of Microbiology
/
v.50
no.1
/
pp.33-39
/
2014
One hundred forty four bacterial colonies which were able to degrade crude oil were isolated from soil samples that were contaminated with oil in Daejeon area. Among them, one bacterial strain was selected for this study based on its emulsification activity, growth rate and surface tension activity, and this selected bacterial strain was identified as Pseudomonas sp. HN37 through physiological- biochemical tests and analysis of its 16S rRNA sequence. Pseudomonas sp. HN37 utilize the several aliphatic hydrocarbons, 3,5-dinitrosalicylic acid and 2,4-dichlorophooxyacetic acid as a sole carbon source. And this bacterial strain showed a high resistance to antibiotics such as ampicillin and chloramphenicol, as well as heavy metals such as Ba, Cr, Li and Mn. Also, it was found that the optimal pH and temperature for the cell growth, surface tension, and emulsification activity of Pseudomonas sp. HN37 were pH 6.0-9.0 and $30^{\circ}C$, respectively. The emulsification and surface tension activity was reached the maximum to 1% (V/V) crude oil and 1% (W/V) NaCl concentration. The surface tension of the culture broth was decreased from 62 to 27 dyne/cm after fifteen hours of inoculation in LB media.
Bak, Sangmin;Seo, Euncheol;Kim, San Yeong;Park, Won Heum;Lee, Su-Heon
Research in Plant Disease
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v.23
no.1
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pp.75-81
/
2017
In May 2016, 24 peach samples showing abnormal and virus like symptoms were collected in one of major peach producing area, Yeongcheon-si, Gyeongsangbuk-do, Korea. We performed RT-PCR diagnosis for confirmation of viral infection. The diagnostic targets are 17 species of viruses and viroids that quarantine and high risk pathogens when it occur. As a results, seven species of viruses and viroids, including an unreported (Apricot pseudo-chlorotic leaf spot virus, APCLSV) and a quarantine (Peach latent mosaic viroid, PLMVd) species in Korea, were detected. For the sequence analysis of unreported virus, APCLSV, the sequence of coat protein gene were amplified and cloned. The sequence showed 97% nucleotide identity with other APCLSV isolates and compared with other seven species of reported Trichoviruses. This virus was classified as APCLSV based on the sequence and phylogenetic analysis. This isolate was named Yeongcheon. As patterns of APCLSV occurrence, all samples that APCLSV detected were co-infected with Apple chlorotic leaf spot virus (ACLSV). As properties of ACLSV, APCLSV has high possibility of wide spread disease in fruit tree farms in Korea. Therefore, it is necessary to do related researches, such as infection route and influence of disease in commercial orchards.
The objective of this study is to present basic data for producing tools to measure Yangseng of the elderly aged older than 65 by reassessing the validity and reliability of such tools already developed. In the present study, total 855 subjects were divided into 4 groups and given 31 question for the ultimate factor analysis of each item. The results cloud be summarized as follows: 1. In case of 'don't have sex in drunken state or right after dinner'(the 31st item of sex live yangseng). factor loading came out proportionally in 3 factors such as factor 4=0.358, factor 5=0.389 and factor 6=0.386. As they all failed to reach the general standard of 0.5 or more and even the minimum standard of 0.4 or more, the 31st item was deleted from the questionnaires. 2. From the factor analysis after exclusion of the 31st item, factor loading of the 25th item of sleep yangseng 'go to bed and get up regularly' appeared to be proportional in 2 factor(factor 4=0.393 and factor 7=0.373). Since it was shown that the 25th item could not be classified into a category but interacted with others in common and didn't satisfy the minimum standard of 0.4, it was deleted form the questionnaires, too. 3. From the factor analysis conducted after excluding the item numbers 31 and 25, factor loading of the 12th item of diet yangseng 'do not eat much' turned out to be relatively high with such values as factor 5=0.518 and factor 3=0.453. As it was, however, tied up with the factor of exercise yangseng, it was also deleted. In conclusion, 28 items after excluding the item numbers 12, 25 and 31 form 4 group showed the same results as divided into 8 factor with high grade of reliability and validity, evidencing the assumption that they can be employed practically to measure yangseng of the elderly aged 65 and oder.
Im, Wanhee;Seo, Dongil;Oh, Kyudeok;Jeong, Young Bin;Youn, Hye Jung;Lee, Hak Lae
Journal of Korea Technical Association of The Pulp and Paper Industry
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v.47
no.5
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pp.91-97
/
2015
Papermakers wish to increase the filler content of printing and writing grades because it allows saving in production cost through fiber replacement and improving the formation, and optical and printing properties of the paper. However, high filler loading in the base paper has negative side effects. It reduces the mechanical properties of paper and induces cracking at the fold after coating process. Fold cracking is one of the most frequent quality complaints for magazines, high quality books, etc. Two approaches were examined as methods to reduce fold cracking. One approach was to use preflocculated fillers, which was expected to reduce the fold cracking because it would decrease the interfiber bonding. The other approach was to use a new coating binder that gives greater binding power and thereby provides an opportunity of reducing the fold cracking of coated paper. When filler preflocculation was employed in producing the base paper, fold cracking becomes more severe than conventional filler loading condition. On the other hand, use of nano sized binder in coating improved the tensile properties of the coating layer and thereby decreased the crack area. It was shown that tensile properties of coating layer played an important role in fold cracking of coating.
The left main descending artery (LMDA) of left coronary artery (LCA) in rats runs around the left side of conus arteriosus after arising from the aortic sinus and descends to the apex of heart with branching several branches into the wall of left ventricle (LV). The ligation site of LMDA for myocardial infarction (MI) is the 2~4 mm from LCA origin, between the pulmonary trunk and left auricle. The characteristics that rat heart has no interventricular groove on the surface and its coronary arteries run intramyocardially with branching several branches give the difficulty in surgery for MI which resulted in expected size. This study was aimed to elucidate the branching patterns of the left coronary artery for analysis of MI size and for giving the basic data to producing small MI intentionally in 2 male species that are widely used, Sprague-Dowley (SD) and Wistar-Kyoto (WKY), in the world. Red latex casting was followed by the microdissection in 27 and 28 hearts of SD and WKY male rats, respectively. The branching patterns of LMDA were classified into 3 major types and others based on the left ventricular branches (L). The Type I, Type II, Type III and others are shown in 55.6%, 22.2%, 14.8%, and 7.4% in SD, 60.7%, 10.7%, 7.1%, and 21.5% in WKY, respectively. The branching number of the first left ventricular branch (L1) that are distribute the upper one third of LV was 1.2~1.5, and its branching sites were ranging 0.9~2.1 ᒠfrom LCA origin. L2, the second left ventricular branch distributing middle one third of LV, was the number of 1.2~1.4 and branching out ranging 5.1~5.7 mm. L3, the third left ventricular branch of LMDA distributing lower one third of LV, was the number of 1~1.5 and branching out ranging 7.0~9.3 mm from LCA origin. The common branch of L1 and L2 was branched from LMDA with the number of 1.1, and its site was located in the distance of mean of 1.5 mm and 2.8 mm in SD and WKY, respectively. The common branch of L2 and L3 was branched from LMDA with the number of 1, and its site was located in the distance of mean of 7.2 mm and 2.9 mm in SD and WKY, respectively. The right ventricular branches (R) of LMDA were short and branched in irregularly compared with L. The number of 1~4 of R were branched from LMDA. With regarding to the distribution area of L and the ligation site for MI, moderate MI (25~35% of LV) might be resulted in 70.4% and 60.7% in SD and WKY rats. Small MI might be produced intentionally if the ligation would be located at the 4~6 mm from LCA origin in the left side of LMDA. These data wold be helpful to expect the size of MI and to reproduce of small MI, intentionally, in rat hearts.
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