• 제목/요약/키워드: primary structure

검색결과 1,747건 처리시간 0.028초

Double-stranded RNA Induces Inflammatory Gene Expression in Schwann Cells: Implication in the Wallerian Degeneration

  • Lee, Hyun-Kyoung;Park, Chan-Hee;Choi, Se-Young;Oh, Seog-Bae;Park, Kyung-Pyo;Kim, Joong-Soo;Lee, Sung-Joong
    • The Korean Journal of Physiology and Pharmacology
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    • 제8권5호
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    • pp.253-257
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    • 2004
  • Schwann cells play an important role in peripheral nerve regeneration. Upon neuronal injury, activated Schwann cells clean up the myelin debris by phagocytosis, and promote neuronal survival and axon outgrowth by secreting various neurotrophic factors. However, it is unclear how the nerve injury induces Schwann cell activation. Recently, it was reported that certain cytoplasmic molecules, which are secreted by cells undergoing necrotic cell death, induce immune cell activation via the toll-like receptors (TLRs). This suggests that the TLRs expressed on Schwann cells may recognize nerve damage by binding to the endogenous ligands secreted by the damaged nerve, thereby inducing Schwann cell activation. Accordingly, this study was undertaken to examine the expression and the function of the TLRs on primary Schwann cells and iSC, a rat Schwann cell line. The transcripts of TLR2, 3, 4, and 9 were detected on the primary Schwann cells as well as on iSC. The stimulation of iSC with poly (I : C), a synthetic ligand for the TLR3, induced the expression of $TNF-{\alpha}$ and RANTES. In addition, poly (I : C) stimulation induced the iNOS expression and nitric oxide secretion in iSC. These results suggest that the TLRs may be involved in the inflammatory activation of Schwann cells, which is observed during Wallerian degeneration after a peripheral nerve injury.

해수펌프 임펠러 샤프트의 구조 재설계 (Structural Re-design of Seawater Pump Impeller Shaft)

  • 조규남
    • 한국해안·해양공학회논문집
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    • 제22권5호
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    • pp.326-332
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    • 2010
  • 해수 임펠러샤프트의 각종 하중에 의한 파단과 이를 개선하기위한 재설계는 정적, 동적 해석을 통한 원인분석과 유한요소법을 이용하여 효과적으로 수행할 수 있다. 본 논문에서는 전형적인 임펠러 샤프트의 파손에 대한 원인 분석을 수행하고 관련된 재설계기법을 제시하였다. 일차적으로 정적구조해석을 수행하였고 다음으로 구조물의 외력과의 공진문제를 포함한 동적해석을 수행하였다. 구조해석은 ANSYS코드를 사용하였으며, 결과적으로 파단원인을 찾아 분석하였다. 주된 파단원인은 과도한 굽힘모멘트의 발생과 응력집중, 구조물의 외력과의 공진에 의한 것으로 분석되었다. 해수 임펠러샤프트의 파단과 관련된 재설계기법의 이론적 배경을 정립하였으며, 재설계기법의 적용성과 정적, 동적 샤프트 재설계에 대한 유용성을 제시하였다.

양자역학적 원자 및 분자 분석에 의한 정공의 이동 불가능성과 운반자로써의 주도 전자에 관한 이론 (A theory on the impossibility of the moving for hle and the primary electron as a carrier using the analyses, by quantum mechanics, of the structure of atoms and molecules)

  • 주정규
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 1998년도 하계종합학술대회논문집
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    • pp.327-330
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    • 1998
  • In this theory, we explained the impossibility of the motion or miving of the hole that has been recognized to be a carrier, by giving some fundamental reasons. We treated energy gap and impurity concentration, in p- and n-type region, as functions of the mobility that is one of te factors which determine current quantity, and analyzed the primary electron theory as a carrier by introducing 2 hypotheses.

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COMPUTER PROGRAMS WHICH ENABLE PRICING OF SHEEP AND LAMB CARCASSES BASED ON YIELD ESTIMATION SUITABILITY AND FINANCIAL PARAMETERS

  • Hopkins, D.L.;Hayhurst, G.;Horcicka, J.V.
    • Asian-Australasian Journal of Animal Sciences
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    • 제5권1호
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    • pp.1-5
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    • 1992
  • A computer program called LAMPRO has been developed for use by the Australian meat industry to assist with the pricing of lamb carcasses. Based on a series of prediction equations and accounting for the cost structure of a meat processor the program allows the real value of a carcass to be established. The concept has also been extended to cater for mutton carcasses destined for either domestic or export markets incorporated in a program called MUTONPRO.

철도 역시설의 입지와 규모에 관한 기초 연구 (A Primary Study on the Location and Size of Railway Station Facilities)

  • 문대섭;이경철;정병현
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2002년도 춘계학술대회 논문집
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    • pp.116-121
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    • 2002
  • This primary study has some bounds md limits owing to the descriptive reviews but not detailed analyses. However, 1 tried to do the comparative analyses and case studies about location and size of rail station for future efficient use of spatial structure. Therefore, I reviewed the location of railway station and some design standards of railway station facilities by type (high speed rail, conventional rail and urban rail), and also, suggested future direction for rail station as the core of city development relating with urban structures and human settlement system reformation.

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동축선회 확산연소기의 1차 및 보조공기유량 변화에 따른 연소배출특성 (Combustion Characteristics in Various Primary and Auxiliary Air Flux Conditions at a Coaxial Swirling Diffusion Combustor)

  • 이용후;오세원;배대석;이도형
    • 동력기계공학회지
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    • 제6권3호
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    • pp.17-23
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    • 2002
  • The purpose of this study is to investigate the combustion emission characteristics changing auxiliary air injection in combustion field of coaxial swirling diffusion combustor. For this purpose, mean temperature, CO, CO2, O2 and HC concentration were measured by changing excess air ratio and auxiliary air injection. As a result of this study, mean temperature, CO2 emission were increased and CO emission decreased by increasing auxiliary air. Therefore, this paper showed the auxiliary air injection effected strongly on flame structure and combustion emission characteristics.

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CONFIDENCE INTERVALS ON THE AMONG GROUP VARIANCE COMPONENT IN A REGRESSION MODEL WITH AN UNBALANCED ONE-FOLD NESTED ERROR STRUCTURE

  • 박동준
    • 한국통계학회:학술대회논문집
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    • 한국통계학회 2002년도 추계 학술발표회 논문집
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    • pp.141-146
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    • 2002
  • In this article we consider the problem of constructing confidence intervals for a linear regression model with nested error structure. A popular approach is the likelihood-based method employed by PROC MIXED of SAS. In this paper, we examine the ability of MIXED to produce confidence intervals that maintain the stated confidence coefficient. Our results suggest the intervals for the regression coefficients work well, but the intervals for the variance component associated with the primary level cannot be recommended. Accordingly, we propose alternative methods for constructing confidence intervals on the primary level variance component. Computer simulation is used to compare the proposed methods. A numerical example and SAS code are provided to demonstrate the methods.

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애드벌룬이 실내 폭파로 인하여 5층 건물이 $\frac{1}{150}$도 이내로 기울어 졌다. (How The 5th floors Bldg structure could be inclined in $\frac{1}{150}$ degree by the explosion of Ad, Balloon in the room)

  • 허진
    • 화약ㆍ발파
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    • 제12권3호
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    • pp.8-16
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    • 1994
  • The primary court house judged that 5th floor's Bldg, structure were inclined 1/150 degree to west-ward by Explosion of Ad, Balloon in the Room. Surveyor made the report to denied the Judgement of primary court. With evidently and Theoritically. but It is waiting the juge of higher court house. Explosion pressure ${\Delta}p$ is as follows $\Delta{p}=4.2100{\times}{\lambda}^{-1.38}=4.2100{\times}{45}^{-1.38}=4.210{\times}{0.00487}=0.02kg/cm^2$.

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국내산 다시마, 미역포자엽, 톳, 모자반 정제 fucoidan의 구성당 결합 특성 (Structural Characterization of Purified Fucoidan from Laminaria religiosa, Sporophylls of Undaria pinnatifida, Hizikia fusiforme and Sagassum fulvellum in Korea)

  • 구재근
    • 한국수산과학회지
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    • 제30권1호
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    • pp.128-131
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    • 1997
  • 국내산 주요 갈조류인 미역, 다시마, 톳, 모자반 정제 fucoidan의 기본 결합 구조 및 황산기 결합 위치를 확인하기 위하여 정제 fucoidan및 이를 methanolysis하여 얻은 고분자 획분을 각각 methylation 및 FT-IR 측정을 하였다. 다시마, 톳, 모자반, 미역포자엽 정제 fucoidan의 주 결합은 $(1\rightarrow3)$ linked fucose였으며 미역포자엽에는 $(1\rightarrow3)$ linked galactose도 상당량 존재하였다. 황산기의 대부분은 fucose와 galactose의 C-4의 위치에 결합되어 있는 것으로 추정된다.

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A Modular Bi-Directional Power Electronic Transformer

  • Gao, Zhigang;Fan, Hui
    • Journal of Power Electronics
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    • 제16권2호
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    • pp.399-413
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    • 2016
  • This paper presents a topology for a modular power electronic transformer (PET) and a control scheme. The proposed PET consists of a cascaded H-Bridge rectifier on the primary side, a high-frequency DC/DC conversion cell in the center, and a cascaded H-Bridge inverter on the secondary side. It is practical to use PETs in power systems to reduce the cost, weight and size. A detailed analysis of the structure is carried out by using equivalent circuit. An algorithm to control the voltages of each capacitor and to maintain the power flow in the PET is established. The merits are analyzed and verified in theory, including the bi-directional power flow, variable voltage/frequency and high power factor on the primary side. The experimental results validated the propose structure and algorithm.