• 대한소아치과학회지
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• 제30권3호
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• pp.453-458
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• 2003

유전치의 인접면 수복에는 흔히 celluloid strip과 wedge를 이용하는 방법 또는 기성품으로 시판되는 celluloid strip crown form을 이용한 방법이 사용된다. 그러나, 이와 같은 방법은 하악에서는 유치의 치관이 작고 치아사이의 발육 공간이 있어 matrix의 견고한 고정이 어려우며, matrix의 강직성으로 인해 풍융한 인접면 형태 및 변연부를 적절히 형성하기 어렵다. 또한 구강이 좁은 소아 환자에서는 술자의 손가락으로 matrix를 지지하기가 불편하다. 이에 저자는 유전치의 인접면을 충전하기 위하여 시중에서 쉽게 구할 수 있는 빨대를 이용하여 편리하면서도 변연부 적합성을 높일 수 있는 변형된 방법을 고안하였다. 이 방법은 증례에 따라 적절히 사용한다면 유전치 수복에 있어 간편하고 효율적인 방법 이 될 것으로 사료된다.

• Fibers and Polymers
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• 제3권3호
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• pp.103-108
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• 2002

The viscosity effect of matrix polymer on melt exfoliation behavior of an organoclay in poly($\varepsilon$-caprolactone) (PCL) was investigated. The viscosity of matrix polymer was controlled by changing the molecular weight of poly($\varepsilon$-eaprolactone), the processing temperature, and the rotor speed of a mini-molder. Applied shear stress facilitates the diffusion of polymer chains into the gallery of silicate layers by breaking silicate agglomerates down into smaller primary particles. When the viscosity of PCL is lower, silicate agglomerates are not perfectly broken into smaller primary particles. At higher viscosity, all of silicate agglomerates are broken down into primary particles, and finally into smaller nano-scale building blocks. It was also found that the degree of exfoliation of silicate layers is dependent upon not only the viscosity of matrix but thermodynamic variables.

• 한국주조공학회지
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• 제15권6호
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• pp.566-573
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• 1995

In this study, the microstructural characteristics such as primary silicon, eutectic silicon, $SiC_p$ dispersion behavior, compound amount and Si solubility in $Al/SiC_p$ composite fabricated by the squeeze casting under various conditions were investigated systematically. As applied pressure(MPa) increases, cooling rate and compound amount are increased. In gravity casting, the cooling rate of hypereutectic composite is slower than of hypoeutectic composite by exothermic reaction of primary Si crystallization. But the cooling rate of hypereutectic composite is faster than that of hypoeutectic composite fabricated by same applied pressure, because amount of primary Si crystallization in hypereutectic composite was decreased, on the contrary, primary ${\alpha}-Al$ in hypoeutetic composite was increased due to increase of Si solubility in matrix by applied pressure. The crystalized primary silicon in hypereutectic composite fabricated by squeeze casting become more fine than that in non-pressure casting This is because mush zone became narrow due to increase of Si content of eutectic composition by pressure and time for growth of primary silicon got shorter according to applied pressure. It is turned out that eutectic temperature and liquidus are decreased by the increasing of squeeze pressure in all the composite due to thermal unstability of matrix owing to increasing of Si solubility in matrix by the increasing of applied pressure, as indicated in thermal anaiysis(DSC) results.

• 한국안전학회지
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• 제13권2호
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• pp.45-53
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• 1998

A method to predict the creep behavior of fiber-reinforced ceramic composites at high temperatures was suggested based on finite element modeling using constituent creep equations of fiber and matrix and showed good agreement with the experimental results. The effects of matrix creep behavior, fiber volume fraction, and residual stresses on the composite creep behavior were also investigated. The results showed that the primary behavior of composites was greatly affected by that of matrix but post-primary behavior was governed by fiber creep characteristics. The increase of fiber volume fraction from 15 vol% to 30 vol% caused the 50% and 40% decrease of steady-state creep rates and total creep strains at $1200^{\circ}C$, 180MPa, respectively. Feasible compressive residual stresses in the matrix caused by different thermal expansion coefficients between the fiber and the matrix could significantly reduce total creep strains of the composite. The creep deformation mechanism in the fiber-reinforced ceramic composites could be explained by the stress transfer and redistribution in the fiber and matrix due to different creep characteristics of its constituents.

• The Korean Journal of Physiology and Pharmacology
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• 제19권4호
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• pp.357-363
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• 2015

The purpose of this study was to compare the inhibitory effect of bevacizumab on human Tenon's fibroblasts (HTFs) cultured from primary and recurrent pterygium. Cultured HTFs were exposed to 2.0, 5.0, 7.5, and 15.0 mg/mL concentration of bevacizumab for 24 hours. The 3-[4,5-dimethylthiazol- 2-yl]-2,5-diphenyl tetrazolium bromide and lactate dehydrogenase leakage assays were then performed to assess fibroblast metabolism and viability. The matrix metalloproteinase (MMP), procollagen type I C terminal propeptide (PIP), and laminin immunoassays were performed to examine extracellular matrix production. Changes in cellular morphology were examined by phase-contrast and transmission electron microscopy. Both metabolic activity and viability of primary and recurrent pterygium HTFs were inhibited by bevacizumab in a dose-dependent manner, especially at concentrations greater than 7.5 mg/mL. Both types of HTFs had significant decreases in MMP-1, PIP, and laminin levels. Distinctly, the inhibitory effect of bevacizumab on MMP-1 level related with collagenase in primary pterygium HTFs was significantly higher than that of recurrent pterygium. Significant changes in cellular density and morphology both occurred at bevacizumab concentrations greater than 7.5 mg/mL. Only primary pterygium HTFs had a reduction in cellular density at a bevacizumab concentration of 5.0 mg/mL. Bevacizumab inhibits primary and recurrent pterygium HTFs in a dose-dependent manner, especially at concentrations greater than 7.5 mg/mL. As the primary HTFs produces larger amounts of MMP-1 compared to recurrent HTFs, significant reduction in MMP-1 level in primary pterygium HTFs after exposure to bevacizumab is likely to be related to the faster cellular density changes in primary pterygium HTFs.

• 대한소아치과학회지
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• 제50권4호
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• pp.396-408
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• 2023

이 연구의 목적은 유구치를 재현한 인공치를 대상으로 인접면 복합레진 수복 시 매트릭스 시스템에 따른 인접면의 외형, 접촉면의 크기 및 수복 전과 후의 부피 차이를 비교해 보는 것이다. 네 가지 종류의 인공치에 Circumferential 매트릭스 시스템에 해당하는 Tofflemire Matrix System과 Sectional 매트릭스 시스템에 해당하는 Palodent V3 Sectional Matrix System, myJunior Kit를 이용하여 복합레진을 수복하고 3D 모델링 과정을 거쳐 분석되었다. Sectional 매트릭스 시스템을 사용한 경우에서 오목한 인접면 외형이 형성될 확률이 높았으며 더 큰 접촉 면적과 부피가 형성되었다. 이는 Sectional 매트릭스 시스템에 사용되는 매트릭스 밴드의 완전 연질(Dead soft) 특성에 의한 변형으로 인해 접촉점 주변으로 과량의 레진이 적용될 수 있기 때문이다. 게다가 Sectional 매트릭스 시스템에 포함된 고무 웨지가 매트릭스 밴드를 와동에 잘 적합 시키지 못할 가능성이 있다. 따라서 이번 연구의 결과를 바탕으로 유구치 인접면을 Sectional 매트릭스 시스템을 이용해 복합레진 수복하는 경우, 형태학적 관점을 고려한 신중한 사용이 요구된다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.84-84
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• 2003

Lead has long been considered as a toxic environmental pollutant, which severely damages central nervous system. Lead can cause hypo- and de-myelination, and glial cells are closely related with myelination or demyelination. Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in the remodelling of the extracellular matrix in a variety of physiological and pathological processes. MMPs also seem to be important in the pathogenesis of inflammatory demyelinating diseases of the central and peripheral nervous system. In this study, we investigated whether lead affects MMP-9 expression in rat primary glial cells. Treatment of 0.1-5 ${\mu}$M lead dose- and time-dependently increased MMP-9 expression in rat primary glial cells. The activity of MMPs was determined using zymography. Lead activated Erk(1/2) but neither of the other endogenous MAP kinases, p38 or JNK. Inhibition of Erk(1/2) activation by PD98059, a MEK inihibitor, prevented lead-induced expression of MMP-9. The results of the present study suggest that lead intoxication may adversely affect brain function at least in part by inducing MMP-9 expression through Erk(1/2) activation in primary glial cells.

• 대한수학회논문집
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• 제38권1호
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• pp.113-120
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• 2023

In this paper, we investigate the dimension and the structure of the centralizer of a square matrix with entries from an arbitrary field.

• Journal of Chest Surgery
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• 제44권6호
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• pp.387-391
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• 2011

Background: The relationship between the degree of expression of matrix metalloproteinases or tissue inhibitor of metalloproteinases and venous reflux remains to be investigated. Materials and Methods: Primary varicose vein tissues were obtained from 23 patients, 18 females and 5 males, aged from 19 to 73. Cephalic or basilic veins were obtained for the control group from 10 patients who underwent vascular access for maintenance hemodialysis. Two operative techniques (high ligation with stripping or endovenous laser coagulation) were used. The expression of matrix metalloproteinase-2 and 13 and tissue inhibitor of metalloproteinase-4 in the varicose vein group and control group was assessed semi-quantitatively by immunohistochemical slides stained with primary antibodies. Results: Twenty (87%) of the varicose vein group patients had greater or lesser saphenous vein diseases with reflux. The focal weak (+) stain for matrix metalloproteinases-2, and 13, and tissue inhibitor of matrix metalloproteinase-4 was dominant in the varicose vein group; the focal or diffuse strong stain (++ or +++) was prevalent in the control group. The differences were statistically significant (p<0.01). The degree of reflux and the duration of symptoms were not significantly related to the expression of MMP-13 (p=0.317 and p=0.654, respectively). Conclusion: Further study should be performed to investigate the relationship between the clinical characteristics related to venous hypertension or reflux and expression of MMPs and TIMP in varicose veins.

• 한국안광학회지
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• 제4권2호
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• pp.51-55
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• 1999

안구운동의 회선점을 중심으로 한 안구운동은 직각좌표의 좌표축 회전변환에 의한 회전행렬 $R_x$, $R_y$, $R_z$로 표현할 수 있으며, 6가지의 눈의 주된 회전 형태인 외-내전, 상-하전, 내-외방 회선 등으로 기술된다. 제1안위에서 제3안위까지의 안구운동은 회전행렬의 조합으로 구성되고, 6가지의 주회전과 8가지의 보조회전으로 6개의 외안근 운동을 표현 할 수 있다. 안구운동에 의한 동공점인 각막정점의 위치를 각각좌표의 회전행렬을 구좌표$(r,{\theta},{\phi})$로 전환하여 9가지로 기술된다.