• 산업공학
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• 제15권1호
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• pp.89-98
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• 2002

This paper considers the optimum replacement times of a steam generator in nuclear power plant with failure data. It is assumed that the failure pattern of units is given as a Weibull distribution and repair and periodic preventive maintenance are performed periodically. The maximum likelihood method is used to estimated the Weibull parameters of failure distribution from failure data. Relpacement, output-decresing and maintenance costs are considered to determine the optimal replacement times by simulation. Numerical examples are included with actual failure data and cost estimators.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.1626-1630
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• 2007

This dissertation finds out trouble types and occurrence regions using the faulty statistics of nondestructive test items in rolling stock parts of the Seoul Metro and using mechanical test about defective and broken parts with broken surface observation, cutting examination about trouble region, hardness experiment and tensile test. Also this dissertation finds out cause of trouble and damage through observation of microscopic formation using metallurgical microscope and scanning electron microscope, residual stress measurement about welding parts and damage diagnosis about defective and broken parts. Moreover it will present the improved plan of nondestructive method about trouble and the removal method of defect and repair welding and find solutions of reliability in parts and preventive maintenance.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2002년도 춘계학술대회논문집
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• pp.189-196
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• 2002

As the quantity of transported goods increases, there is a lot of mechanical trouble with loading facilities. So it tremendously produces not only economic loss but also time loss. To reduce the loss from the trouble of leading facilities, it is necessary to analyse the distribution of the problem's occurrence and use the analyzed data to minimize the outbreak of trouble. So the data can be usefully used when designing or manufacturing and it also can be utilized for proper maintenance of operating equipment, frequency of inspection and repair, know-how of checking on equipment and purchasing of spare parts. And it is possible to minimize the loss if the propel maintenance is adapted

• International Journal of Reliability and Applications
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• 제14권2호
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• pp.55-70
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• 2013

This paper deals with the Bayesian analysis of the failure data of a repairable mechanical system subject to minimal repairs and periodic overhauls. The effect of overhauls on the reliability of the system is modeled by a proportional age reduction model and the failure process between two successive overhauls is assumed to be 2-parameter Engelhardt-Bain process (2-EBP). Power Law Process (PLP) model has a disadvantage which 2-EBP can overcome. On the basis of the observed data and of a number of suitable prior densities, point and interval estimation of model parameters, as well as quantities of relevant interest are found. Also hypothesis tests on the effectiveness of performed overhauls have been developed using Bayes factor. Sensitivity analysis of improvement parameter is carried out. Finally, a numerical application is used to illustrate the proposed method.

• 대한건축학회논문집:계획계
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• 제34권10호
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• pp.63-73
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• 2018

As the life cycle of buildings is expected to increase, new constructions will decrease and the proportion of remodeling and repair will increase. Therefore, there is an increasing need for overall performance management of old buildings. In 2020, the proportion of buildings over 30 years old is expected to reach a half. As a result, the demand for securing and improving the performance in the stage of using the building is increasing due to the change in the demand for the building, such as the decrease in the construction permit and the increase in the use of the existing building. From this perspective, the study sought to consider institutional measures to organize the preventive and conservative maintenance of buildings. For this purpose, the conceptual goals of inspection for building maintenance were set through a literature review, and the status and problems associated with building maintenance were analyzed to suggest ways to improve the inspection system for building maintenance.

• Molecular & Cellular Toxicology
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• 제2권3호
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• pp.202-211
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• 2006

Our objective is to identify molecular factors which contribute to the increased risk of smoke in human. About 677 workers who had control and experimental groups according to their urinary Naphthol levels were enrolled in our study. In the present study, we investigated the effects of smoking on gene expression profiles in human. We determined differential gene expression patterns in smoker versus non-smoker using cDNA microarray. Specific genes were up-or down-regulated according to smoking and age. Inflammatory related genes such as cytokine, interleukin, and tumor necrosis factor were up-regulated, DNA repair related genes such as high-mobility group (nonhistone chromosomal) protein 1, and protein 2 were down-regulated, apoptosis related genes such as myeloperoxidase and Bcl-2-associated athanogene were down-regulated, and cell cycle related genes were down-regulated. In our epidemiological study, notably, inflammatory, DNA repair, apoptosis, signal transduction, metabolism, cell cycle, cell proliferation, transcription related genes were regulated.

• 교육시설 논문지
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• 제24권6호
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• pp.11-18
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• 2017

Education facilities have much affect to make a good condition for the learning environment. Therefore, various approaches have been conducted to improve the physical, social and educational achievement. Especially, the physical aspect is very important to get rid of the building defect and improve the student their learning environment. For these, it needs to explain the performance and function of components and materials, which is linked with the deterioration degree. The deterioration degree is a imperative factor to make a decision whether the component would be repaired or not and to provide the repair scope of its component. In this paper, it aimed at making the deterioration degree model of roof proof under the hypothesis of which deterioration degree would be equal the repair cost at this time. Results of the study are shown that first, the $3^{rd}$ function is most proper to explain the deterioration degree model among 11 functions in view of resulted statistics. Second, the inflection of deterioration is shown at 15yr of the elementary school and 13yr of the middle and high school. This study has a limit of disclassification of the component or materials and it is, therefore, favorable to include the classification of waterproof material and work. These results would make a change from the breakdown maintenance to preventive maintenance and give a decent the learning environment for student.

• Journal of Korean Neurosurgical Society
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• 제64권5호
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• pp.799-807
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• 2021

Objective : Cerebrospinal fluid leakage related complications (CLC) occasionally occur after intradural spinal surgery. We sought to investigate the effectiveness of early ambulation after intradural spinal surgery and analyze the risk factors for CLC. Methods : For this retrospective cohort study, we enrolled 314 patients who underwent intradural spinal surgery at a single institution. The early group contained 79 patients who started ambulation after 1 day of bedrest without position restrictions, while the late group consisted of 235 patients who started ambulation after at least 3 days of bed rest and were limited to the prone position after surgery. In the early group, Prolene 6-0 was used as the dura suture material, while black silk 5-0 was used as the dura suture material in the late group. Results : The overall incidence rate of CLC was 10.8%. Significant differences between the early and late groups were identified in the rate of CLC (2.5% vs. 13.6%), surgical repair required (1.3% vs. 7.7%), and length of hospital stay (2.99 vs. 9.29 days) (p<0.05). Logistic regression analysis revealed that CLC was associated with practices specific to the late group (p=0.011) and the revision surgery (p=0.022). Conclusion : Using Prolene 6-0 as a dura suture material for intradural spinal surgery resulted in lower CLC rates compared to black silk 5-0 sutures despite a shorter bed rest period. Our findings revealed that suture - needle ratio related to dura defect was the most critical factor for CLC. One-day ambulation after primary dura closure using Prolene 6-0 sutures appears to be a costeffective and safe strategy for intradural spinal surgery.

• Journal of Preventive Medicine and Public Health
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• 제32권1호
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• pp.101-107
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• 1999

Objectives. To determine the effects of exposure to hexavalent chromium, 93 male Sprague-Dawley rats were exposed to hexavalent chromium solution. Methods. Rats were divided into 4 groups and exposed to 0.1ml of 0 mM, 0.4 mM, 2.0 mM, and 10.0 mM potassium chromate in the first experiment, and to 0.1 ml of 0 mM, 20 mM, 40 mM, and 80 mM in the second for consecutive 3 days by tracheal instillation. Three and 10 rats were the controls for the first and the second experiments, respectively. Lung tissues were then removed to measure the 8-hydroxydeoxyguanosine (8-OH-dG) level using the HPLC-ECD method, superoxide dismutase (SOD) activity using the cytochrome C method, and 8-hydroxyguanine endonuclease activity using the oligonucleotide nicking assay. Results. The results showed no significant linear relationship between chromium exposure level and 8-OH-dG level or 8-hydroxyguanine endonuclease activity. In the first experiment, 8-OH-dG level and 8-hydroxyguanine endonuclease activity increased in 0.4 mM group, and then decreased in 2.0 mM and 10.0 mM groups. The correlation coefficients between 8-OH-dG level and 8-hydroxyguanine endonuclease activity was statistically significant (P<0.01), and total SOD activity was elevated by chromium exposure in a dose-dependent manner (P<0.05). In contrast, there was no significant dose-response pattern or correlation in the secod experiment. Conclusions. Based on the fact that there was no linear relationship between chromium dose and 8-OH-dG level or activity of the repair enzyme, it seems unlikely that 8-OH-dG formation is the major mechanism of chromium carcinogenesis.

• 한국해안·해양공학회논문집
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• 제28권4호
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• pp.191-201
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• 2016

추계학적 확률과정을 이용하여 경사제 피복재를 예방적으로 유지관리할 수 있는 조건기반모형을 개발하였다. 완전 보수보강 조건에서 가장 경제적으로 보수보강이 수행되어야 하는 최적의 시점을 결정할 수 있는 모형이다. 본 연구에서 개발된 RRP(Renewal Reward Process) 기반 경제성 모형은 이자율을 고려할 수 있을 뿐만 아니라 기존 연구에서 상수로 취급하던 비용을 시간에 따른 확률변수로 고려할 수 있다. 누적피해와 사용한계 그리고 구조물의 중요도를 모두 고려할 수 있는 함수식을 제시하여 ABM(Age-Based Maintenance)을 CBM(Condition-Based Maintenance)으로 쉽게 확장할 수 있게 하였다. 또한 함수식에 포함된 계수들을 수학적으로 산정할 수 있는 방법도 제시하였다. 두 가지 추계학적 확률과정, WP(Wiener Process)와 GP(Gamma Process)를 이용하여 경사제 사석재를 해석하였다. 사용한계, 이자율 그리고 구조물의 중요도에 따라 시간에 따른 기대총비용율을 산정하여 기대총비용율이 최소가 되는 예방적 유지관리의 최적 시점을 쉽게 추정할 수 있었다. 동일한 사용한계에서 이자율이 높을수록 최적시점은 늦어지고 그에 따라 기대총비용율도 낮아졌다. 또한 상대적으로 GP가 WP보다 더 보수적으로 최적시점을 예측하였다. 마지막으로 동일한 조건에서 구조물의 중요도가 높을수록 더 자주 예방적 보수보강을 실시하여야 한다는 것을 알았다.