• Title/Summary/Keyword: preventive potential

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Adipocyte and Chemokines: A Link between Preadipocyte/Adipocyte and Macrophage in Adipocyte- Related Pathologies

  • Yu, Rina
    • Preventive Nutrition and Food Science
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    • 제9권2호
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    • pp.194-198
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    • 2004
  • This review will present a brief overview on the adipocytokines and chemokines in terms of their classifications and functions, and further discuss the most recent results of chemokine research into their regulation of adipocyte functions and/or adipocyte-related pathologies. The potential link between preadipocytes/adipocytes and macrophages will also be highlighted.

NOVEL LEAD STRUCTURES AND MECHANISMS FOR CANCER CHEMOPREVENTION

  • Gerhauser, C.
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.35-36
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    • 2001
  • Nutrition influences cancer incidence and offers a variety of preventive dietary factors including non-nutritive plant metabolites. To identify novel potential chemopreventive agents, we have set up cell- and enzyme-based in vitro marker systems relevant for prevention of carcinogenesis in vivo. This experimental approach led to the identification of Xanthohumol (Xn), a prenylated chalcone from hop (Humulus lupulus L.) as a most promising broad-spectrum chemopreventive agent.(omitted)

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Applications of Gelatin in Food and Biotechnology

  • Yang, Jae-Sung
    • Preventive Nutrition and Food Science
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    • 제2권3호
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    • pp.263-268
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    • 1997
  • Gelatin is a high molecular weight polypeptide derived fro mcollgen, theprimary protein component of animal connective tissues, which include bone, skin and tendon. Gelatin is usually produced from two different sources of raw materials (skins or bones) which are processed in two ways(line or acid). According to this pretreatment, gelatin can be divided into elatin type A(acid) and B(lime). The market is essentially driven by thre demand sectors: food, harmaceuticals(capsules) and photography. Although there is some potential threat in the photography sector, the oher tow sectors are well placed for futher growth.

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Nanotechnology Applications in Functional Foods; Opportunities and Challenges

  • Singh, Harjinder
    • Preventive Nutrition and Food Science
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    • 제21권1호
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    • pp.1-8
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    • 2016
  • Increasing knowledge on the link between diet and human health has generated a lot of interest in the development of functional foods. However, several challenges, including discovering of beneficial compounds, establishing optimal intake levels, and developing adequate food delivering matrix and product formulations, need to be addressed. A number of new processes and materials derived from nanotechnology have the potential to provide new solutions in many of these fronts. Nanotechnology is concerned with the manipulation of materials at the atomic and molecular scales to create structures that are less than 100 nm in size in one dimension. By carefully choosing the molecular components, it seems possible to design particles with different surface properties. Several food-based nanodelivery vehicles, such as protein-polysaccharide coacervates, multiple emulsions, liposomes and cochleates have been developed on a laboratory scale, but there have been very limited applications in real food systems. There are also public concerns about potential negative effects of nanotechnology-based delivery systems on human health. This paper provides an overview of the new opportunities and challenges for nanotechnology-based systems in future functional food development.

Flavonoid Fraction Purified from Rhus verniciflua Stokes Actively Inhibits Cell Growth Via Induction of Apoptosis in Mouse Tumorigenic Hepatocytes

  • Lee, Jeong-Chae
    • Natural Product Sciences
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    • 제10권2호
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    • pp.74-79
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    • 2004
  • Dietary flavonoids are currently receiving considerable attention in developing novel cancer-preventive approaches because of their potential capacities to actively induce apoptosis of cancer cells. In our previous report, a flavonoid fraction, which consisted mainly of protocatechuic acid, fustin, fisetin, sulfuretin, and butein and named RCMF (RVS chloroform-methanol fraction), was prepared from a crude acetone extract of Rhus verniciflua Stokes (RVS) that is traditionally used as food additive and herbal medicine. In this study, we evaluated the effects of the RCMF on cell proliferation and apoptosis using SV40-transformed tumorigenic hepatocytes, BNL SV A.8. Tritium uptake assay showing the proliferative capacity of the cells was strongly suppressed in the presence of RCMF. This anti-proliferative effect was further confirmed through trypan blue exclusion. RCMF-mediated suppression of cell growth was verified to be apoptotic, based on the increase in DNA fragmentation, low fluorescence intensity in nuclei after propidium iodide staining, and the appearance of DNA laddering. Collectively, this study demonstrated that RCMF can be approached as a potential agent that is capable of significantly inhibiting cell growth of hepatic cancer cells.

Are Beta Blockers New Potential Anticancer Agents?

  • Akbar, Shahid;Alsharidah, Mansour Saleh
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권22호
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    • pp.9567-9574
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    • 2014
  • ${\beta}$-Blockers have been one of the most widely used and versatile drugs for the past half a century. A new potential for their use as anti-cancer drugs has emerged in the past few years. Various retrospective case control studies have been suggestive that use of ${\beta}$-blockers before the diagnosis of cancer could have preventive and protective effects against non-small cell lung carcinoma, melanoma, and breast, pancreatic and prostate cancers. Experimental and clinical observations are still inconclusive with some inconsistent findings. However, indications are pointing toward a positive role of some ${\beta}$-blockers against certain forms of cancers. This mini review is an effort to present the up to date published results of case-control studies and experimental findings.

아동성폭력 예방을 위한 행동기술훈련의 효과에 관한 연구 (The Effectiveness of Behavioral Skill Training for the Prevention of Child Sexual Abuse)

  • 손승아
    • 아동학회지
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    • 제13권2호
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    • pp.189-201
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    • 1992
  • The purpose of this study was to investigate the effectiveness of teaching personal safety skills for prevention of potential child sexual abuse in Korean society. The subjects of this study were 80 first grade female students, sampled from elementary schools in Seoul. The instruments of this study were the Personal Safety Questionnaire (PSQ) and 'What if' Situations Test (WIST) modified by the present researcher. The t-test and Pearson's correlation coefficient were applied to analyze the data of this study. The results of the analysis were (1) after the Behavioral Skills Training, the children of the training group showed a higher level of knowledge about child sexual abuse than the control group. (2) After the Behavioral Skills Training, the children of the training group showed more adequate self-defensive skills than the control group when they faced situations of possible child sexual abuse. (3) The higher the level of knowledge about child sexual abuse, the more adequate self-defensive skills in situations of child sexual abuse. These results supported the effectiveness of Behavioral Skills Training as preventive education on potential child sexual abuse.

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초고층 빌딩의 화재 피해 최소화 방안에 관한 연구 (Research of the Fire to Minimization Damage Plan on High-rise Buildings)

  • 이정일;이근태
    • 한국화재소방학회논문지
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    • 제23권4호
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    • pp.91-97
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    • 2009
  • 초고층 건물이라는 특수 장소에서 화재가 발생하였을 경우에 야기될 수 있는 제반 문제점을 도출하여 인적, 물적 피해를 최소화하기 위해서 초고층 건물 내에 존재하는 잠재위험요인을 찾아내 위험이 얼마나 큰가를 분석하여 그 해결 방안을 모색하여야 한다. 예방적 측면에서 화재예방활동을 통하여 화재의 발생을 억제하거나, 진압적 측면에서 화재발생과 동시에 초기 진화하는 것이겠지만, 화재의 진행과정을 미리 예측하거나 진행경로를 차단하는 인텔리젠트 또는 파이어 그리드를 이용한 과학소방적 진압방안의 도입이 필요하다.

In vitro Antioxidant Activities of Trianthema portulacastrum L. Hydrolysates

  • Yaqoob, Sadaf;Sultana, Bushra;Mushtaq, Muhammad
    • Preventive Nutrition and Food Science
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    • 제19권1호
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    • pp.27-33
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    • 2014
  • Hydrolysates of Trianthema portulacastrum in acidified methanol were evaluated for their total phenolic (TP) constituents and respective antioxidant activities using in vitro assays (i.e., 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, percent inhibition of linoleic acid peroxidation, and ferric reducing power). The observed results indicate that root, shoot, and leaf fractions of T. portulacastrum contain 50.75~98.09 mg gallic acid equivalents/g dry weight of TP. In addition, these fractions have substantial reducing potentials (0.10~0.59), abilities to inhibit peroxidation (43.26~89.98%), and DPPH radical scavenging capabilities ($6.98{\sim}311.61{\mu}g/mL$ $IC_{50}$). The experimental data not only reveal T. portulacastrum as potential source of valuable antioxidants, but also indicate that acidified methanol may be an ideal choice for the enhanced recovery of phenolic compounds with retained biological potential for the food and pharmaceutical industry.