• Korean Journal of Health Education and Promotion
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• v.18 no.1
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• pp.61-78
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• 2001

The purpose of this research was to find out plans to promote the fulfillment of the breast self-examination and breast cancer screening, which is preventive health behavior about women's having breast cancer exam in some part of our country with searching for the primary causes which have an effect on their fulfillment. The subjects of the study were 540 literate volunteers who were of age from 20 to 69 and who visited 8 health centers in Taegu. The survey research was made through questionares in the 8 health centers in Taegu from the 15th to the 30th of September, 1998. Based on Becker's health belief model asking medical staff's opinions with bibliographies, the major findings from the survey was as follow. The fulfillment rate of the breast self-examination and the breast cancer screening was 37.8％(204 subjects), 27.6％ (149 subjects) each. Getting breast self-exam varied significantly depending on subject's age, income of family, religion, occupation and the number of children. As far as the breast cancer screening was concerned, there was remarkably significant difference in accordance with their age, marital status, religion, occupation, income of family, the number of children, ways of nursing and parturition age of the first baby. The subjects in their forties accounted for the highest rate. Based on the fulfillment of the breast self-examination and the breast cancer screening, the average points of all the variables presented from the health belief as well as the points of the susceptibility, seriousness, benefits, knowledge and level of health concern of interest in health were significantly higher than the points of non-fulfillment of them in the statistical analysis whereas the barriers was lower than them. In consequence of the multiple-logistic regression analysis putting the breast self-examination and the breast cancer screening in dependent variables, occupation, knowledge, seriousness, benefits, barriers and cues to action had significant effects on breast self-examination against breast cancer. Looking more attainments, thinking diseases more seriously, feeling more usefulness and there being any patient around with breast cancer led to the higher rate of the breast self-examination against it. On the other hand, feeling more impedition as well as housewives caused the lower rate of it. The breast cancer screening was significantly affected by age, sensitivity, usefulness, impedition and behavior momentum as well. The cases who are older, feeling more sensitivity against breast cancer, more usefulness of the examination and where any patient around, the fulfillment rate was higher. Contrarily the more impedition they felt, the lower the fulfillment rate was. Accordingly, the study of the causes, which have significant effects on the fulfillment of the self-examination and the breast cancer screening in order to find it in an early stage, and the development of health education programs as well as proper education for public health through carrying on campaigns and stepping up public relations must be indispensable.

• Research in Community and Public Health Nursing
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• v.11 no.2
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• pp.538-555
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• 2000

The purpose of this study, in which 573 students from 2 high schools in Kang Nung city participated was to identify the attitude and experience of sexual harassment. This information will provide useful data, and promote a more systematic sexual harassment education program. The subjects of this study were 278 male students and 295 female students. The data was collected from September 25 to October 6. 2000. The data was analyzed using the statistical Computer package. SPSS to manipulate the data along with frequency, percentage, and mean t-test. The results from this study were summarized as follows. 1. The results from this comparison between two groups were significant in their attitude on sexual harassment(t=-2.26. p=0.024). Female students had higher scores than male students. 2. As a cause of sexual harassment. 'A man's misjudgement regarding a women as sexual objects(n=130: 22.7%)'. 'Patriarchal system of unequal distribution of power and status between the sexes(n=105: 18.3%)'. 'The effect of sexual stimulatives. (pornography. pornovideo. TV program ect.)(n=89: 15.5%)'. 3. As a countermeasure for prevention, 'Punishment, law and regulation of the sexual harasser(n = 151; 26.4%)', 'A preventive education of sexual harassment in adolescence (n = 125: 21.8%)'. 'Reformation of gender inequality and sex discrimination in the socio-structure(n=76; 13.3%)'. 4. Out of 573 students who participated in this study, 209(36.5%) students reported experiencing an incident of sexual harassment. For 278 males who participated in this study, 88(31.7%) had experienced an incident of sexual harassment. For the 295 females who participated in this study, 121(41.0%) had experienced an incident of sexual harassment. The type of sexual harassment is reported physical sexual harassment(n = 248: 40.5%), verbal sexual harassment(n = 226; 36.7%), and visual sexual harassment(n=139: 22.6%). 5. Their age in which they had experienced harassment was usually 'after 16 years of age(n=122: 58.4%)'. The age of harassers were mostly teenagers(n=112; 53.6%). The relationship to the with sexual harasser was a stranger (n=85; 40.7%), or a friend(n=78: 37.3%). After the incident of sexual harassment occurred, some students informed friends (n=114: 54.5%), 63(30.1%) told no one. Male students' feelings after the experienced harassment ranged from: 'be interesting', 'be pleasant'. Female students' feelings after the experienced harassment ranged from; 'be surprised', 'get a shock', 'fear', 'shame'.

• Preventive Nutrition and Food Science
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• v.8 no.1
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• pp.46-53
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• 2003

The current study investigated the effect of Korean safflower (Carthamus tinctorius L.) seed powder and its water and ethanol extracts on bone metabolism during recovery from rib-fracture induced by surgical operation in rats. 10-week-old male Sprague-Dawley rats weighing about 320 g were divided into 9 groups after arrival: 10d control (AIN 76 semi-purified diet), 10d safflower seed powder (10d SS-powder), 10d safflower seed ethanol extract (10d SS-EtOH), 10d safflower seed water extract (10d SS-$H_2O$), 20d control (AIN-76 semi-purified diet), 20d safflower heed powder (20d SS-powder), 20d safflower seed ethanol extract (20d SS-EtOH), 20d safflower seed water extract (20d SS-$H_2O$), and 20d sham-operation (20d sham), The dietary level for all the supplements was 5% based on the raw material weight. The rats were fed the experimental diets for 10 days before the rib fracture operation and for a further 10 or 20 days after the operation. A number 9 rib was fractured surgically and a sham-operation also performed. The rats were then sacrificed on the l0th or 20th day after the operation. The body weight initially decreased after the operation in all the rib-fractured groups, then gradually recovered. The concentrations of plasma osteocalcin were higher in the control group than in all the safflower-supplemented groups 10 and 20 days after the rib-fracture (p < 0.05). The bone-specific ALP (alkaline phosphatase) activity was significantly higher in the SS-EtOH group than in the other groups 20 days after the rib-fracture (p < 0.05). The level of urinary DPD (deoxypridinoline) was significantly higher in the SS-EtOH and SS-$H_2O$ groups than in the other groups 10 days after the rib-fracture. When comparing the PTH (parathyroid hormone) and calcitonin levels, the SS-$H_2O$ group exhibited the highest PTH level among the groups 10 and 20 days after the rib-fracture. Thus, it was concluded that the bone turnover during the fracture-healing period was more rapid in the rats supplemented with safflower seed powder or its fractions than in the control rats. Furthermore, the SS-$H_2O$ fraction was identified as the most effective in stimulating bone remodeling, as bone resorption and bone formation were both significantly increased during fracture healing when compared to the control group.

• Journal of Pharmacopuncture
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• v.18 no.1
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• pp.56-62
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• 2015

Objectives: The purpose of the study is to assess both the approximate lethal dose and the single dose intramuscular injection toxicity of Danggui (Angelica gigantis radix) pharmacopuncture (DGP) in Sprague-Dawley (SD) rats. Methods: The experiments were conducted at the good laboratory practice (GLP) laboratory, Biotoxtech Co., which is a laboratory approved by the ministry of food and drug safety (MFDS). The study was performed according to the GLP regulation and the toxicity test guidelines of the MFDS (2009) after approval of the institutional animal care and use committee of Biotoxtech. Single doses of DGP were injected intramuscularly into the rats in three test groups of 6 week old SD rats (5 male and 5 female rats per groups) in the amounts of 0.1, 0.5, and 1.0 mL/animal for groups 2, 3, and 4, respectively, and normal saline solution in the amount of 1.0 mL/animal was injected intramuscularly into the rats (5 male and 5 female rats) in the control group. Observations of the general symptoms and weight measurements were performed during the 14 day observation period after the injection. Hematologic and serum biochemical examination, necropsy, and a local tolerance test at the injection site were done after the observation period. Results: No death was observed in three test groups (0.1, 0.5 and 1.0 mL/animal group). In addition, the injection of DGP had no effect on general symptoms, weights, hematologic and serum biochemical examination, and necropsy. The results from the local tolerance tests at injection site showed no treatment related effects in the SD rats. Conclusion: The results of single dose intramuscular injection of DGP suggest that the approximate lethal dose is above 1.0 mL/animal for both male and female SD rats and that intramuscular injection of DGP may be safe.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.8
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• pp.210-220
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• 2017

This study investigated the effect of social support (MOS-SSS), and physical (ADL, IADL) and mental (CES-D, MMSE-K) function on the quality of life (WHOQOL- BREF) among the elderly at care facilities. The survey respondents were 524 elderly aged 65 and older living in 15 care facilities located in D city. Data were collected through a personal interview conducted by interviewers who visited each care facility from November 2015 to January 2016. As a result, the quality of life was significantly lower in the elderly group with lower social support, with dysfunction in ADL and IADL than in the normal range group, with depression and cognitive impairment group than in the normal range group. The quality of life had a significant positive correlation with social support, ADL, IADL and cognitive impairment, but a significant negative correlation with depression. According to the results of covariance structure analysis, physical function had a greater impact on the quality of life than mental function or social support. Lower quality of life was associated with lower physical and mental function and lower social support. Therefore, concrete measures need to be devised to enhance physical function in order to improve the quality of life among the elderly in care facilities.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.6
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• pp.4040-4047
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• 2015

The purpose of this study was to analyze a change in Post-traumatic Stress Disorder (PTSD) level and the continuity of the effects in music therapy by applying short-term music therapy program in fire fighters with Post-traumatic Stress (PTS). Forty two fire fighters in 3 districts were randomly assigned to experimental group (21 subjects) and control group (21 subjects). Music therapy was applied in totally 10 sessions by two sessions (120 minutes) a day for 5 days. PTS level was measured immediately after the end of program, after 4 weeks, and after 12 weeks. As a result, PTS level has significantly decreased into $8.90{\pm}4.55$ from $26.52{\pm}2.32$ right after the music therapy program(p<0.05). And the effect was shown to be continued significantly up to after 4 weeks($11.95{\pm}4.57$) and after 12 weeks($13.76{\pm}5.62$)(p<0.05). As a result of research, it is considered that the music therapy is effective approach for reduction in PTS as for fire fighters who belong to the group with high risk of PTSD. Accordingly, the application of regular program for managing fire fighters' mental health is understood to likely to contribute to enhancing the field service competence.

• Korean Journal of Veterinary Research
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• v.21 no.1
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• pp.51-58
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• 1981

Two experiments were conducted to establish a program for the prevention of swine parakeratosis occurred recently in Korea. In the first experiment, 11 rations which were considered to be related clinico-pathologically to the incidence of parakeratosis and 5 rations not to be related were collected at farms during the period from June, 1979 to December, 1980. In addition, 23 commercial rations and 10 ingredients were also collected at feed dealers or farms. The feed samples were analyzed for calcium, zinc and unsaturated fatty acid. In the second experiment, the efficiencies of adding zinc carbonate (150mg/kg diet) with or without soybean oil (5ml/kg diet) to two control rations were tested using 20 weanling pigs. One of the control rations had low zinc (41mg/kg) and normal calcium (0.64%) and the other low zinc (57mg/kg) and high calcium (1.42%). The results obtained are as follow: 1. Content of zinc in the rations induced parakeratosis ranged from 35 to 80mg/kg with a mean of 49mg/kg; whereas those of rations not induced ranged from 97 to 182mg/kg with a mean of 182mg/kg. The difference between two means was highly significant (p<0.01). 2. The calcium content in rations related to parakeratosis was ranged from 0.56 to 1.80% with a mean of 1.30% whereas that of not related was ranged from 0.63 to 1.37% with a mean of 1.07%. The highly significant difference of calcium content between two rations were recognized (p<0.01). The calcium contents of both rations were markedly higher than that of generally recommended value of 0.40~0.80%. 3. The contents of unsaturated fatty acid in induced rations was a mean of 4.42% and it was significantly lower (p<0.01) compared with those in not induced rations with a mean of 6.70%. The content of unsaturated fatty acid of commercial rations was ranged from 5.25 to 7.81% with a mean of 6.29%. 4. Zinc content of 15 commercial ration samples among 23 were less than 97mg/kg and 21 rations contained more than 1.03% of calcium. 5. Addition of zinc carbonate to the two control rations which are low in zinc content or high in calcium content were resulted in preventive effect on the incidence of swine parakeratosis. 6. It may be concluded that the incidence of swine parakeratosis was closely related to the low zinc, excess calcium and low unsaturated fatty acid in rations, most of the commercial rations contained low in zinc and high in calcium as compared with the recommended contents. Content of Unsaturated fatty acids in the commercial rations, however, were sufficient for the prevention of parakeratosis in swine.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1497-1501
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• 2006

The therapeutic anti-diabetic effect of Nelumbo Folium and a poly herbal formula (NOC) was evaluated in the streptozotocin (STZ 60 mg/kg, I.p.) induced diabetic rats. For this study, test articles were orally administrated once a day from 7 d after STZ-injection for 3 weeks. The fasting blood glucose, body weight, pancreas weight changes, oral glucose tolerance test, hemoglobin Alc (Hb A1c) level changes and the histopathological changes were observed. WNL-treated rat had lower fasting blood glucose levels compared to control group and NOC-treated rat had significantly lower fasting blood glucose levels, compared to control group (p < 0.05). After 21 days of extract treatment, body weight in control was reduced (p < 0.001). WNL and NOC groups were also reduced compared to control group but insignificantly. Pancreas weight of control group was reduced (p < 0.001), but the weight of NOC group were increased (P< 0.05). During the 2 h oral glucose tolerance test (OGTT), WNL group were improved compared to control group (P < 0.05). NOC group were improved compared to control group but insignificantly. WNL and NOC groups had lower Hb Alc level compared to control group. In addition, atrophy of islet and decrease of insulin-producing cells were detected in STZ induced diabetes rats. However, these diabetic changes were decreased in WNL and NOC groups. These results suggest that N. Folium and NOC have favorable effects to inhibit the changes on the fasting blood glucose levels, pancreas weight, glucose tolerance, hemoglobin Alc and the histopathological changes of pancreas in STZ-induced diabetes.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.3 no.1
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• pp.86-93
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• 2003

Background : The SCL began screening of newborns and high risk group blood spots with tandem mass spectrometry (MS/MS) in April 2001. Our goal was to determine approximate prevalence of metabolic disorders, optimization of decision criteria for estimation of preventive effect with early diagnosis. This report describes the ongoing effort to identify more than 30 metabolic disorders by MS/MS in South Korea. Methods : Blood spot was collected from day 2 to 30 (mostly from day 2 to 10) after birth for newborn. Blood spot of high risk group was from the pediatric patients in NICU, developmental delay, mental retardation, strong family history of metabolic disorders. One punch (3.2 mm ID) of dried blood spots was extracted with $150{\mu}L$ of methanol containing isotopically labelled amino acids (AA) and acylcarnitines (AC) internal standards. Butanolic HCl was added and incubated at $65^{\circ}C$ for 15 min. The butylated extract was introduced into the inlet of MS/MS. Neutral loss of m/z 102 and parent ion mode of m/z 85 were set for the analyses of AA and AC, respectively. Diagnosis was confirmed by repeating acylcarnitine profile, urine organic acid and plasma amino acid analysis, direct enzyme assay, or molecular testing. Results : Approximately 31,000 neonates and children were screened and the estimated prevalence (newborn/high risk group), sensitivity, specificity and recall rate amounted to 1:2384/1:2066, 96.55%, 99.98%, and 0.73%, respectively. Confirmed 28 (0.09%) multiple metabolic disorders (newborn/high risk) were as follows; 13 amino acid disorders [classical PKU (3/4), BH4 deficient-hyperphenylalaninemia (0/1), Citrullinemia (1/0), Homocystinuria (0/2), Hypermethioninemia (0/1), Tyrosinemia (1/0)], 8 organic acidurias [Propionic aciduria (2/1), Methylmalonic aciduria (0/1), Isovaleric aciduria (1/1), 3-methylcrotonylglycineuria (1/0), Glutaric aciduria type1 (1/0)], 7 fatty acid oxidation disorders [LCHAD def. (2/2), Mitochondrial TFP def. (0/1), VLCAD def. (1/0), LC3KT def. (0/1). Conclnsion : The relatively normal development of 10 patients with metabolic disorders among newborns (except for the expired) demonstrates the usefulness of newborn screening by MS/MS for early diagnosis and medical intervention. However, close coordination between the MS/MS screening laboratory and the metabolic clinic/biochmical geneticists is needed to determine proper decision of screening parameters, confirmation diagnosis, follow-up scheme and additional tests.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.1
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• pp.27-39
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• 2008

Landslides cause enormous economic losses and casualties. Korea has mountainous regions and heavy slopes in most parts of the land and has consistently built new roads and large-scale housing complexes according to its industrial and urban growth. As a result, the damage from landslides becomes greater every year. In summer, landslides frequently occur due to local torrential rains and storms. It is critical to predict the potential areas of landslides in advance and to take preventive measures to minimize consequences and to protect property and human life. The previous study on landslides mostly focused on identifying the causes of landslides in the areas where they occurred, and on analyzing landslide vulnerability around the areas without considering rainfall conditions. Thus there were not enough evaluations of the direct risk of landslides to human life. In this study, potentially risky areas for landslides were identified using the GIS data in order to evaluate direct risk on farmlands, roads, and artificial structures that were closely connected to human life. A map of landslide risk was made taking into account rainfall conditions, and a land use map was also drawn with satellite images and digital maps. Both maps were used to identify potentially risky areas for landslides.