• 대한치과보철학회지
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• 제47권3호
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• pp.348-355
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• 2009

연구 목적: ShadeEye-Ncc dental chroma meter (Shofu Inc., Kyoto, Japan)와 Shadepilot$^{TM}$ system (Degudent Inc., Hanau, Germany)의 도재색조 재현의 정확성을 비교연구하여 보고자 함이다. 연구 재료 및 방법: ShadeEye-Ncc dental chroma meter와 Shadepilot$^{TM}$ system을 사용하여 Vitapan 3D Master shade guide의 2M2와 3M2 shade tap.을 측색하고, 이 자료를 통하여 shade guide tap. 형태로 도재시편을 제작한다. 시편제작 시 사용하는 porcelain system은 ShadeEye-Ncc dental chroma meter는 Vintage Halo Porcelain system을, Shadepilot$^{TM}$ system은 VitaOmega900 Porcelain system을 사용한다. 모델인 shade tap.과 제작된 도재시편을 spectrophotometer로 측색하고, 그 결과를 토대로하여 ${\Delta}E$를 계산하여, 두 측색기의 정확성을 비교검증하였다. 결과: 1. Shadepilot$^{TM}$ system이 ShadeEye-Ncc dental chroma meter에 비하여 더 적합한 도재색조 재현성을 나타내었다 (P <.05). 2. 모델인 Shade tap.의 shade에 따라서 도재색조 재현성에 차이를 나타내었다. 2M2 shade tap.에 비하여 3M2 shade tap.에서 더 적합한 도재색조 재현성을 나타내었다 (P <.05). 3. 두 측색기 모두에서 제작된 도재시편의 ${\Delta}E$가 평균4.44-6.14로 육안으로 구분 가능한 정도의 색조차이를 보였다. 결론: Shadepilot$^{TM}$ system이 비교적 더 정확한 도재색조 재현성을 나타낸다고 할 수 있으며, ShadeEye-Ncc dental chroma meter를 사용할 때는 치아 전체의 여러부분에서 측색을 하여 정확성을 높이는 것이 필요하리라 생각된다.

• 치위생과학회지
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• 제17권2호
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• pp.123-133
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• 2017

본 연구에서는 국제적인 치위생계의 임상실무와 교육의 표준인 치위생 관리 과정을 기반으로 표준화된 치위생 교육기관인 미국 폰즈스쿨의 임상치위생학 교육과정에 대해 심층분석 함으로써 국내 실정에 맞는 임상치위생학 교육과정의 표준화 방안에 대해 고찰해 보고자 하였다. 2015~2016년 폰즈스쿨의 임상치위생학은 모두 'Dental Hygiene Clinical Practice (DHYG)'라는 과목명으로 운영되었고, 실습의 비중이 매우 컸으며, 실습강의는 교수 1명당 학생 5명이 한 팀으로 운영되었다. 폰즈스쿨의 학과 목표는 브릿지포트 대학교의 미션에 따라 설정되었고, 폰즈스쿨의 임상치위생학 교육목표 또한 폰즈스쿨의 학과 목표에 기반하여 설정되었다. 또한, 임상치위생학의 교육목표는 ADHA에서 제시한 치위생임상 실무표준에 따라 개발되었고, 이를 기반으로 임상치위생학 교육을 통해 달성해야 하는 임상 핵심역량과 세부역량을 제시하고 있었다. 임상치위생학 교육내용은 다양한 대상자에게 적절한 치위생 관리 과정을 제공하기 위한 이론 및 실습으로 구성되었고, 특히, 졸업 후 실제 임상 현장에서 수행하게 될 업무에 대한 실습내용이 다뤄졌다. 학생은 대상자/환자별로 수행한 술식에 문서를 작성하여 교수자와 함께 검토 및 보완작업을 통해 치위생 임상역량을 높이고자 하였다. 실습내용 중 치위생 관리 과정 실습은 필수적으로 어린이, 청소년, 성인, 노인, 특별환자를 대상으로 선정해야 하며, 구강 상태에 따라 중등도 이상의 치주환자를 포함해야 했다. 이론평가는 지필고사 혹은 사례연구 발표 등으로 이루어졌고, 실습평가는 주로 임상역량의 달성 정도에 따라 평가되었다. 특히 교수자의 로테이션 평가를 실시하였는데, 이를 통해 모든 학생의 임상역량 달성 정도를 파악하고 부족한 역량에 대해 개선방안을 함께 모색하는 과정을 수행하였다. 본 연구는 ADHA에서 제시하는 치위생임상 실무표준에 따라 운영되고 있는 표준화된 임상치위생학 교육과정을 심층적으로 분석함으로써 향후 우리나라 임상치위생학의 개선방향을 모색하기 위한 기초 자료로 제시될 수 있을 것이라 판단되었다.

• 대한치과기공학회지
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• 제34권1호
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• pp.25-36
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• 2012

Purpose: The purpose of this study is to investigate the status of oral health behaviors and oral health status, and to analysis the association between health behavior and chronic disease and oral health status of male workers. Methods: The survey used structured self administered questionnaires from September to October in 2009 in Daegu and Gyeongsangbuk-do province, randomize thirty workplace which work more than 50 workers and carry out a survey targeting 30 to 50 age male laborers who work selected workplace. Total of 1,532 replies were analysed. Results: Age, education, monthly income, job was significantly associated with number of toothbrushing, scaling experience, number of missing teeth. Smoking, amount of smoking, frequency of drinking, number of tooth brushing, unmet need and subjective oral health condition, HBP and DM was significantly associated with the number of missing teeth. In logistic regression, age(above 40), monthly income and DM were significant factors on loss of teeth. Conclusion: In conclusion, it is important to provide education on the teeth-brushing and DM management to workers engaged in a small or medium sized workplace with many tooth loss and low educational status, and to recommend a regular scaling as well as to establish policy for creating conditions upon an oral health check-up and a tooth scaling and allow the maintenance of an oral health.

• The Journal of Advanced Prosthodontics
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• 제9권3호
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• pp.195-199
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• 2017

PURPOSE. The objective of this study was to determine the cumulative survival rate (CSR) and associated risk factors of Implantium implants by retrospective clinical study. MATERIALS AND METHODS. Patients who received Implantium implants (Dentium Co., Seoul, Korea) at Korea University Guro Hospital from 2004 to 2011 were included. The period between the first surgery and the last hospital visit until December 2015 was set as the observation period for this study. Clinical and radiographic data were collected from patient records, including all complications observed during the follow-up period. Kaplan-Meier analysis was performed to examine CSR. Multiple Cox proportional hazard model was employed to assess the associations between potential risk factors and CSR. RESULTS. A total of 370 implants were placed in 121 patients (mean age, 56.1 years; range, 19 to 75 years). Of the 370 implants, 13 failed, including 7 implants that were lost before loading. The 10-year cumulative survival rate of implants was 94.8%. The multiple Cox proportional hazard model revealed that significant risk factor of implant failure were smoking and maxillary implant (P<.05). CONCLUSION. The 10-year CSR of Implantium implants was 94.8%. Risk factors of implant failure were smoking and maxillary implant.

• 대한치과기공학회지
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• 제35권1호
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• pp.1-17
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• 2013

Purpose: This study was to assess the extents of the release of metals from the non-precious alloys used for dental casting by measuring the differences in the extents of the release of metals by types of alloys, pH level and elapsed time. Methods: Uniform-sized specimens(10 each) were prepared according to the Medical Device Standard of the Korea Food and Drug Administration(2010) and International Standard Organization(ISO22674, 2006), using four types of alloys(one type of Ni-Cr and one type of Co-Cr used for fixed prosthesis, and one type of Ni-Cr and one type of Co-Cr used for removable prosthesis). A total of 12 metal-release tests were performed at one-day, three-day, and two-week intervals, for up to 20 weeks. The metal ions were quantified using an Inductively Coupled Plasma-Atomic Emission Spectrometer. Results: The results showed that the extent of corrosion was higher in the ascending order of Jdium-$100^{(R)}$, Bellabond-$Plus^{(R)}$, Starloy-$C^{(R)}$, and Biosil-$F^{(R)}$. The lower the pH and the longer the elapsed time were, the greater the increase in metal corrosion. At pH 2.4, the release of Ni from Jdium-$100^{(R)}$, a Ni-Cr alloy, was up to 15 times greater than the release of Co from the Co-Cr alloy from two weeks over time, indicating that the Ni-Cr alloy is more susceptible to corrosion than the Co-Cr alloy. Conclusion: It is recommended that Co-Cr alloy, which is highly resistant to corrosion, be used for making dental prosthesis with a non-precious alloy for dental casting, and that non-precious alloy prosthesis be designed in such a way as to minimize the area of its oral exposure. For patients with non-precious alloy prostheses, a test of the presence or absence of periodontal tissue inflammation or allergic reaction around the prosthesis should be performed via regular examination, and education on the good management of the prosthesis is needed.

• Preventive Nutrition and Food Science
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• 제12권3호
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• pp.148-153
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• 2007

Obesity-induced inflammation plays a crucial role in obesity-related pathologies such as type II diabetes and atherosclerosis. Adipose tissue macrophages and the cell-derived proinflammatory chemokines are key components in augmenting inflammatory responses in obesity. Anthocyanins such as cyanidin and $cyanidin-3-O-{\beta}-D-glucoside$ (C3G) are known to elicit anti-inflammatory activities by suppressing the production of proinflammatory mediators such as tumor necrosis factor alpha and nitric oxide in LPS-stimulated macrophages. In the present study, we investigated whether cyanidin and C3G have the potential to suppress the inflammatory responses of adipose cells. Cyanidin and C3G not only suppressed the migration of RAW 264.7 macrophages induced by mesenteric adipose tissue-conditioned medium, but also inhibited the activation of the cells to produce inflammatory chemokines such as monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-related protein-2 (MRP-2) in a dose-dependent manner. Cyanidin and C3G also inhibited the release of MCP-1 and MRP-2 from adipocytes and/or macrophages. These findings suggest that cyanidin and C3G may suppress the inflammatory responses of adipose tissue in obesity.

• 한국치위생학회지
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• 제12권2호
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• pp.275-284
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• 2012

Objectives : The purpose of this study was to examine the oral health behavior of shipbuilding company workers in some regions in a bid to provide information on the oral health plans for industrial fields. Methods : The subjects in this study were 310 workers in 10 shipbuilding companies and suppliers in Jeolla Namdo Province, on whom a self-administered survey was conducted. Results : 1. Concerning general information about the subjects who participated in the research, gender was possessed 94.8% by men and 5.2% by women. Age was the largest in 31~40 years old with 44.2%. Marital status was the largest in the married with 64.5%. It was the largest in under high school graduate with 71.9% for academic background, in 2,000,000 won~3,000,000 won with 49.0% for monthly family income, and in cooking with 33.9% for work field. 2. Research subjects' toothbrushing time was indicated to be the largest in after having breakfast. It was indicated to be twice a day with 41.3% for toothbrushing frequency. 90.3% of the respondents are not using auxiliary oral hygiene devices. 3. Recognition on periodontal health status was found larger in workers whose response was that their own periodontal health status is 'healthy' than workers who responded that their status is 'not healthy.' Workers, who don't have subjective symptom on periodontal status, were indicated to be larger. 4. Ratio of subjects with tooth scaling experience accounted for 59.7%. The ratio of tooth scaling experience was indicated to be different depending on academic background and monthly family income. Conclusions : Academic credential, monthly family income and the line of work were identified as the main factors to affect oral health care of the shipbuilding workers. Oral health education and dynamic implementation of corporate oral health promotion which are designed to meet the needs of workers are required.

• 한국치위생학회지
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• 제11권1호
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• pp.113-126
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• 2011

Objectives : We supposed that identifying the influencing factors on DMFT index in the primary school children in Pocheon be indispensible for the primary school children's oral health program establishment in Pocheon. So, to prepare the basic materials for the primary school children's oral health program establishment in Pocheon, we analyzed the associated factors which could have an influence on the primary school children's DMFT index in Pocheon. Methods : We selected 3,676 primary school children in Pocheon, whose age were from 6 to 11, and surveyed those children by a questionnaire and the oral examination based on WHO's oral health survey method. Data were analyzed with a $x^2$-test and multiple regression analysis using SPSS $15.0^{(R)}$. Results : The results of oral survey in the primary school children in Pocheon revealed as follows: DMFT index, National Health Oral health survey of 2006 people nationwide in the results when compared to younger grade children and older grade in the low and the higher. Subjective oral health awareness, high of viscosity junk food snacks, fruit, gender, dental visits and humidity, oral health education classes, including the variable of attitude was 6(p<0.05). Their higher awareness of dental health, oral health education classes ever the more positive attitude to DMFT index was statistically significant(p<0.05). Solid in the habit of eating junk food snacks to the students of a liquid relative to student intake was higher DMFT index indices(p<0.05). Conclusions : We could reason that one's oral health recognition and behavior should have a relationship with his(her) DMFT index.

• Journal of Microbiology and Biotechnology
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• 제25권3호
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• pp.393-398
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• 2015

Aptamers are composed of single-stranded oilgonucleotides that can selectively bind desired molecules. It has been reported that RNA or DNA could act as not only a genetic messenger but also a catalyst in metabolic pathways. RNA aptamers (average sizes 40-50 bp) are smaller than antibodies and have strong binding capacities to target molecules, similar to antigenantibody interactions. Once an aptamer was selected, it can be readily produced in large quantities at low cost. The objectives of this study are to screen and develop aptamers specific to oral pathogens such as Porphyromonas gingivalis, Treponema denticola, and Streptococcus mutans. The bacterial cell pellet was fixed with formaldehyde as a target molecule for the screening of aptamers. The SELEX method was used for the screening of aptamers and a modified western blot analysis was used to verify their specificities. Through SELEX, 40 kinds of aptamers were selected and the specificity of the aptamers to the bacterial cells was confirmed by modified western blot analysis. Through the SELEX method, 40 aptamers that specifically bind to oral pathogens were screened and isolated. The aptamers showed possibility as effective candidates for the detection agents of oral infections.

• The Korean Journal of Physiology and Pharmacology
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• 제9권3호
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• pp.149-153
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• 2005

The aim of the present study was to determine whether serotonergic drugs could reverse lipopolysaccharide (LPS)-induced anorexia in rats. LPS ($500{\mu}g$/kg body weight) and all serotonergic drugs, except for 8-OH-DPAT (subcutaneous), were injected intraperitoneally into Sprague-Dawley rats. Without the LPS injection, 8-OH-DPAT (1A agonist), metergoline (1/2 antagonist), and mianserin (2A/2C antagonist) exerted no effects on food intake at any of the doses tested, but ketanserin (2A antagonist) caused an increase of food intake at 4 mg/kg. RS-102221 (2C antagonist) reduced food intake at 2 and 4 mg/kg. LPS reduced food intake 1 hour after injection, and food intake remained low until the end of measurement period (24 hours) (p<0.05). Pretreatment of rats with 8-OH-DPAT partially recovered of cumulative food intake at all measured times (2, 4, 6, 8, and 24 hours after LPS injection). Pretreatment with metergoline resulted in a partial recovery of cumulative food intake at 2, 4, 6, and 8 hours, but not at 24 hours. Ketanserin caused partial recovery at 2 and 4 hours only. Mianserin and RS-102221 had no effects on LPS-reduced food intake. A variety of serotonergic drugs ameliorated anorexic symptoms, which suggesting that the serotonin system plays a role in LPS-induced anorexia.