• The Korean Journal of Physiology and Pharmacology
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• 제3권3호
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• pp.321-328
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• 1999

Pulmonary blood vessels with diameters of $200{\sim}400\;{\mu}m$ produce considerably more force in response to vasoconstrictor drugs than those which are either smaller or larger. We have therefore investigated whether or not hypoxic pulmonary vasoconstriction (HPV) is more powerful in vessels of these diameters. We have also looked at the possibility that vessels from different regions of the lung respond differently. To do this we have grouped vessels according to their location within the lung as well as by size. We used a small vessel myograph (Cambustion AM10, Cambridge, UK) to study 208 preconstricted $(1\;{\mu}M\;PGF_{2{\alpha}})$ small pulmonary arteries $(300{\sim}800\;{\mu}m$ diameter when stretched to a tension equivalent to 25 mmHg transmural pressure) from 39 rats anaesthetized with 2% inspired halothane. A biphasic contraction was observed in response to hypoxia (ca. 25 mmHg $Po_2).$ The magnitudes of both the first, transient, phase (PT, peak tension) and of the second, sustained, phase (SST, steady state tension) were measured. The latter was measured 40 min after the start of hypoxia. The first phase was most pronounced in vessels with an average diameter of 423 ${\mu}m$ while the second phase was most pronounced in larger vessels (mean diameter 505 ${\mu}m).$ These maximal responses were all seen in vessels somewhat larger than reported by others. The responses of smaller vessels $(400{\sim}500\;{\mu}m)$ did not depend upon their location within the lung, but those of larger vessels $(600{\sim}700\;{\mu}m)$ showed regional differences. Those from the right lobe and those from the base of the lung gave the largest responses. It was especially noticeable that large vessels (631 ${\mu}m$ diameter) from the base of the right lung gave the biggest responses. Thus HPV seems to occur not in a uniform manner, dependent solely to the size of vessels, but it also depends to some degree on the region of the lung from which vessels have been taken. Furthermore, our results suggest that larger vessels, as well as smaller ones, may contribute significantly to HPV.

• 대한기계학회논문집B
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• 제35권11호
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• pp.1219-1227
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• 2011

최근 생활 환경의 변화로 혈관계 질병으로 고통 받는 사람들이 늘어가고 있다. 이에 따라 질병을 치료하기 위해 여러 가지 시술을 하게 되는데 있어서 혈관의 역학적인 분석과 해석이 확보되어야 한다. 본 논문에서는 초탄성 이론을 기초로 하여 탄성 대변형에서의 혈관의 역학적인 거동에 대해 알아 보았다. 이를 통하여 정상혈압과 고혈압일 때 혈관에 작용하는 응력과 열림각으로 나타낼 수 있는 잔류 응력의 효과가 각 방향 응력분포에 미치는 영향에 대해 연구하였다. 그 결과 잔류응력 효과를 적용시켰을 때 혈관 벽내에 작용하는 최대응력은 잔류응력 효과가 없을 경우와 비교하여 약 50%응력 감소가 나타남을 확인할 수 있고, 고혈압의 경우 정상혈압일 때보다 2배정도의 큰 응력이 혈관벽에 작용함을 확인 할 수 있었다.

• 한국가스학회지
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• 제9권1호
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• pp.26-32
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• 2005

본 논문에서는 고압용기의 밀봉을 위해 사용하는 메탈시일의 설계 안전성에 대한 연구결과를 제시하고 있다. 기본적으로 고압용기의 1차적 밀봉은 메탈시일에 의해 이루어지고, 2차적 밀봉은 탄성체 고무로 제작된 0-링에 의해 가스누출이 차단된다. 유한요소해석 결과에 의하면, 가스누출 차단을 위해 사용한 알루미늄 소재의 밀봉장치는 강재를 사용한 경우보다 우수한 밀봉성을 보여주고 있다. 이것은 알루미늄 소재의 열팽창 특성이 상대적으로 우수하기 때문이다. 메탈시일과 압력용기 구조물에 걸리는 변형과 응력분포는 외부에서 공급된 가스압보다는 용기 내부에서 전달된 온도차에 의해 크게 지배를 받는 것으로 알려져 있다. 따라서 메탈시일의 소재는 통상적으로 $200^{\circ}C$이하로 유지되는 것이 소재의 강도와 밀봉성 측면에서 안전하다.

• 한국압력기기공학회 논문집
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• 제15권1호
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• pp.18-27
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• 2019

The Advanced Power Reactor 1400 (APR1400) Steam Generator (SG) uses alloy 690 as a tube material and SA-508 Grade 3 Class 1 as a tubesheet material to form tube-to-tubesheet joint through hydraulic expansion process. In this paper, the residual stresses in the SG tube-to-tubesheet contact area was investigated by applying Model-Based System Engineering (MBSE) methodology and the V-model. The use of MBSE transform system description into diagrams which clearly describe the logical interaction between functions hence minimizes the risk of ambiguity. A theoretical and Finite Element Methodology (FEM) was used to assess and compare the residual stresses in the tube-to-tubesheet contact area. Additionally, the axial strength of the tube to tubesheet joint based on the pull-out force against the contact joint force was evaluated and recommended optimum autofrettage pressure to minimize residual stresses in the transition zone given. A single U-tube hole and tubesheet with ligament thickness was taken as a single cylinder and plane strain condition was assumed. An iterative method was used in FEM simulation to find the limit autofrettage pressure at which pull-out force and contact force are of the same magnitude. The joint contact force was estimated to be 20 times more than the pull-out force and the limit autofrettage pressure was estimated to be 141.85MPa.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.178-186
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• 2007

This study is attempted to correct an error of electronic blood pressure meter with an optical sensor. In general, for a hospitalized patient, ECG, blood pressure, oxygen saturation, and respiration are basically measured to monitor the patient's condition. Opening of a blood vessel after it is occluded by pressurizing the cuff influences the blood flow of peripheral blood vessels as well as oscillation changes in the cuff. Blood vessels are occluded and peripheral blood flow disappears at cuff pressure above the examinee's blood pressure, while blood vessels are opened and peripheral blood flow appears again at cuff pressure under the examinee's blood pressure. Then Disappear-Appear Point Length(DAPL) of peripheral blood flow can be judged with the signal of peripheral blood flow, thus is available as a factor of error correction for electronic blood pressure meter. Also, systolic or diastolic blood pressure can be corrected with Appear-Point-Pressure(APP) of cuff pressure at a point where blood flow occurs and Appear-Maximum Pressure(AMP) of cuff pressure at the maximum amplitude point of peripheral blood flow after peripheral blood flow appears again. For verification, 27 examinees were selected, and their blood value was obtained through experimental procedure of 4 stages including induction of blood pressure change. The examinees were divided into two groups of experimental group and control group, regression analysis was conducted for experimental group, and correction of a blood pressure error was verified with optical signal by applying the regression equation calculated in experimental group to control group. As an experimental result, mean of the whole measurement errors was 5mmHg or more, which did not meet the standard fur blood pressure meter. As a result of correcting blood pressure measurements with data of DAPL, APP, and AMP as drawn out of PPG signal, systolic blood pressure, mean blood pressure, and diastolic blood pressure were $-0.6{\pm}4.4mmHg,\;-1.0{\pm}3.9mmHg$ and $-1.3{\pm}5.4mmHg$, respectively, indicating that mean of the whole measurement errors was greatly improved, and standard deviation was decreased.

• 한국정밀공학회지
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• 제20권1호
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• pp.205-213
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• 2003

The fiber reinforced composite material is widely used in the multi-industrial field where the weight reduction of the infrastructure is demanded because of their high specific modulus and specific strength. It has two main merits which are to cut down energy by reducing weight and to prevent explosive damage preceding to the sudden bursting which is generated by the pressure leakage condition. Therefore, Pressure vessels using this composite material in comparison with conventional metal vessels can be applied in the field such as defense industry, aerospace industry and rocket motor case where lightweight and the high pressure are demanded. In this paper, for nonlinear finite element analysis of E-glass/epoxy filament winding composite pressure vessel receiving an internal pressure, the standard interpretation model is developed by using the ANSYS, general commercial software, which is verified as the accuracy and useful characteristic of the solution based on Auto LISP and ANSYS APDL. Both the preprocessor for doing exclusive analysis of filament winding composite pressure vessel and postprocessor that simplifies result of analysis have been developed to help the design engineers.

• 한국압력기기공학회 논문집
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• 제17권1호
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• pp.28-35
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• 2021

The flow accelerated corrosion (FAC) is one of significant aging and degradation mechanism and can affect structural integrity of CANDU feeder pipes. Pipe burst can occur under normal operation pressure (min. 10 MPa) if wall-thinning of the feeder pipe due to FAC is accumulated. Previous studies considered simple shapes of feeder pipe with local wall-thinning in order to conservatively assess structural integrity of wall-thinned feeder pipe. In this paper, a new FE model is developed, having an actual shape of the feeder pipe (double bent) as well as the actual wall-thinning shape and location based on the in-service inspection result. Then, the burst pressure assessment of the wall-thinned feeder pipe is performed using lower bound limit load analysis considering elastic-perfectly plastic material. In addition, an improved formulation to predict the burst pressure of the wall-thinned feeder pipe is presented and the safety margin is compared with an existing assessment method.

• 한국압력기기공학회 논문집
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• 제5권1호
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• pp.25-31
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• 2009

Steam Generator(SG) tube is an important component of Nuclear Power Plant(NPP), which comprises of the pressure boundary of primary system. The integrity of SG tube has been confirmed by the eddy current test every outage. In Korea, Bobbin probe and MRPC probe have been generally used for the eddy current test. Meanwhile the usage of Array probe has gradually increased in U.S., Japan and other countries. In this study, we investigated the defect detection capability of the Array probe through its preliminary application to SG tube inspection. The Array probe has the equivalent capability in the defect detection and sizing as the conventional methods. Thus it is desirable that the Array probe is generally applied to SG tube inspection in the domestic NPPs.

• 한국압력기기공학회 논문집
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• 제5권1호
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• pp.20-24
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• 2009

There is extensive tubing pipe in the nuclear power plant under high temperature and pressure. Erosion and corrosion defects are expected on this tubing pipe due to environmental and mechanical factors. In this study, Guided Ultrasonic Wave technique was applied to detect defects. The technique explores the advantages of the Guided Ultrasonic Wave method that inspects along the wall of the pipe and can travel long distances, providing rapid collection of data. This paper presents a case study of the Guided Ultrasonic Wave testing of 3/8" tubing pipe. This study offers to understand detected signals through correlation between amplitude and depth of defects.

• 한국압력기기공학회 논문집
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• 제5권1호
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• pp.9-13
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• 2009

The containment local leakage rate testing in nuclear power plants is performed in accordance with ANSI/ANS-56.8(1994) in Korea. Two methods, the make-up flow rate and the pressure decay, are used for LLRT. Though ANSI/ANS-56.8 does not define clearly the minimum test duration for the make-up flow rate method, it requires obtaining the data after reaching the stable condition. Thus the prerequisite stable condition for data acquisition and the test period for type "C" LLRT is differently applied to each NPPs. Therefore, this study presents a unified test criteria for data stabilization and test duration through experiments to improve the test reliability for type "C".