• The Journal of the Society of Korean Medicine Diagnostics
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• v.18 no.3
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• pp.137-148
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• 2014

Objectives This study was conducted to derive consensus about physical attributes in pressure pulse waveform and pulse conditions by Delphi study. Methods Delphi research was conducted for 2 rounds via e-mail. 8 Professors who lecture on a diagnostics of K. M. from the society of Korean medicine diagnostics were participated in this survey. They were asked for answering about series of definition for a physical attribute in pressure pulse waveform and combination for physical attributes of pulse conditions. Results 4 survey items were decided to have high validity and 9 survey items were decided to come to consensus about a physical attribute in pressure pulse waveform. 6 pulse condition were decided to come to consensus. Conclusion Using Delphi method, physical attributes in pressure pulse waveform and combinations of physical attribute in pulse condition come to consensus.

• Korean Journal of Acupuncture
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• v.27 no.4
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• pp.59-72
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• 2010

Objectives : In the study on the waveform analysis of radial artery pulse diagnosis, we need to establish fundaments of contemporary pulse diagnosis research, and to find the change of pulse waveform parameter with applied variation pf pressure. Methods : As we will to do experimental research on the difference of pulse waveform on the radial artery with applied variations of pressure(5 stage-pressure) and measuring position(left KWAN). In this research, we analyzed the change of the waveform according to five stage pressure. Results : The results were as follows; When we analyzed the change of the waveform according to pressure in the left KWAN, E, hl, h2 and A were the difference between 8ths pressure grades in 95% trust section. And t2, t4 were the difference between 8ths pressure grades in 95% trust section. W was the difference between 8ths pressure grades in 95% trust section. And h2/h1 was the difference between 6ths pressure grades in 95% trust section. There is the difference between 1st and 2nd grade & between 2nd and 5th grade in the case of t4/t2 in 95% trust section. And there is the difference between 1st and 5th grade, between 3rd and 4th grade, between 3rd and 5th grade & between 4th and 5th grade in the case of W/A in 95% trust section. And there is the difference between 1st and 2nd grade, between 2nd and 3rd grade, between 2nd and 4th grade, between 3rd and 4th grade, between 3rd and 5th grade & between 4th and 5th grade in the case of A/E in 95% trust section. Conclusions : We found the statistically resonable differences between each pulse depending on the applied pressure. And Analysing the radial pulse(left KWAN) at 5 applied pressure levels may be useful to study on the pulse waveform diagnosis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.1
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• pp.186-191
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• 2009

In the study on the waveform analysis of radial artery pulse diagnosis, we need to establish fundaments of contemporary pulse diagnosis research. As we will to do experimental research on the difference of pulse waveform on the radial artery with applied variations of pressure(5 stage-pressure) and measuring position(CHON, KWAN, CHEOG). First of all, in this research, we did the experiment of the study on the waveform analysis of radial artery(left KWAN) pulse dignosis by using 3 dimension pulse meter and analyzer (3D MAC). As a result. we extracted the seven measurement fluents : energy(E), size of cycle(h1), size of reflection cycle(h2), time of reflection cycle(t2), time of contraction (t4), width of cycle(w), area of waveform(A) by the statistically reasonable differences. We expect that the seven measurement fluents contribute to divide the situation through the results of waveform analysis of radial artery.

• The Journal of Korean Medicine
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• v.30 no.3
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• pp.98-105
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• 2009

Objective: Increased aortic and carotid arterial augmentation index (AI) is associated with the risk of cardiovascular disease. The most widely used approach for determining central arterial AI is by calculating the aortic pressure waveform from radial arterial waveforms using a transfer function. But how the change of waveform by applied pressure and the pattern of the change rely on subject's characteristics has not been recognized. In this study, we use a new method for measuring radial waveform and observe the change of waveform and the deviation of radial AI in the same position by applied pressure. Method: Forty-six non-patient volunteers (31 men and 15 women, age range 21-58 years) were enrolled for this study. Informed consent in a form approved by the institutional review board was obtained in all subjects. Blood pressure was measured on the left upper arm using an oscillometric method, radial pressure waves were recorded with the use of an improved automated tonometry device. DMP-3000(DAEYOMEDI Co., Ltd. Ansan, Korea) has robotics mechanism to scan and trace automatically. For each subject, we performed the procedure 5 times for each applied pressure level. We could thus obtain 5 different radial pulse waveforms for the same person's same position at different applied pressures. All these processes were repeated twice for test reproducibility. Result: Aortic AI, peripheral AI and radial AI were higher in women than in men (P<0.01), radial AI strongly correlated with aortic AI, and radial AI was consistently approximately 39% higher than aortic AI. Relationship between representative radial AI of DMP-3000 and peripheral AI of SphygmoCor had strongly correlation. And there were three patterns in change of pulse waveform. Conclusion: In this study, it is revealed the new device was sufficient to measure how radial AI and radial waveform from the same person at the same time change under applied pressure and it had inverse-proportion to applied pressure.

• Journal of Sensor Science and Technology
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• v.27 no.4
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• pp.259-263
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• 2018

A radial artery pulse wave is measured while pressing an artery with constant force. However, pulse waveform measurements vary depending on pressing force and direction. Accurate pulse waveform measurements are important for analysis. Thus, it is necessary to define the measurement range of the permissible force and direction from which a correct pulse waveform is derived. In this study, pulse waves were generated by a pulse wave generator for accurate control. The pulse waves generated for different angles and pressing forces were analyzed. The augmentation index (AIx), which is the most commonly used index for evaluating vascular stiffness, was analyzed. The AIx was measured within ${\pm}6^{\circ}$ of the vessel direction and within ${\pm}8^{\circ}$ perpendicular to the vessel direction with a force that was 25% or more of the pressing force at which the maximum pressure wave was generated. We identified the applicable pressing force and angle range by analyzing the effect of pressing angle on the pulse wave. The AIx analysis performed using the pulse wave measurement device is reliable and reproducible.

• KIPS Transactions on Computer and Communication Systems
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• v.5 no.6
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• pp.135-142
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• 2016

We proposed the new method to estimate the blood pressure with the differential value of the digital arterial pulse waveform and BP relation equation. To get the digital arterial pulse waveform, we use the arterial pulse waveform measurement system that has digital air-pressure sensor device and smart phone. The acquired digital arterial pulse waveforms are classified as hypertension group, normal group, and hypotension group, and we can derive the average differential value between the highest point and lowest point of a single waveform of individuals along with the group. In this study, we found the functional correlation between the blood pressure and differential value as a form of BP relation equation through the regression process on the average of differential value and blood pressure value from a tonometer. The Experimental results show the BP relation equation can give easy blood pressure estimation method with a high accuracy. Although this estimation method has over 66 % error rate and does not give the high level of the accuracy for the diastolic compares to the commercial tonometer, the estimation results for the systolic show the high accuracy that has less than 10 % error rate.

• Korean Journal of Acupuncture
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• v.27 no.1
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• pp.13-22
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• 2010

Objectives: The information on the depth where pulse wave appears is as important as pulse waveform. The aim of this study was to classify pulse pattern using pressure-height(P-H) volume-curve by 5 applied pressure levels to find out the information on the depth of pulse and interpret the floating & sinking pulse in oriental medical pulse diagnosis. Methods: We used 3 dimensional pulse imaging analyser (DMP-3000, DAEYOMEDI Co., Korea), which measures radial pulse waveforms noninvasively by way of tonometric method at 5 applied pressure levels, and shows P-H volume-curves by applied pressure. 448 subjects were enrolled, pulse waveforms were measured and the P-H volume-curves were gained on the three locations of Chon, Kwan, and Cheok. Results: Gained P-H volume curves were classified into 3 types ; increase type, decrease type, and increase-decrease type. Increase-decrease type appeared more often on Chon and Kwan, while increase type appeared more often on Cheok. In a few cases, decrease-type appeared on Chon and Kawn, however it never appeared on Cheok. Conclusions: Through the classification of pulse by P-H volume-curve, we gained the information on the depth of pulse. We speculate the decrease type as floating pulse, the increase-decrease type as middle pulse, and the increase type as sinking pulse in oriental medical pulse diagnosis. After more researches on P-H volume-curve by applied pressure, the P-H volume-curve may be used as an important factor for pulse diagnosis.

• Journal of Sensor Science and Technology
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• v.26 no.2
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• pp.135-140
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• 2017

In this paper, a novel measurement method of radial artery pulse waveform using robotic applanation tonometry (RAT) was present to reduce the errors by the pressing direction of the vessel. The RAT consisted of an array of pressure sensors and 2-axis tilt sensor, which was attached to the universal joint with a linear spring and five-DOF robotic manipulator with a one-axis force sensor. Using the RAT mechanism, the pulse sensor could be manipulated to perpendicularly pressurize the radial artery. A pilot experimental result showed that the proposed mechanism could find the optimal pressurization angles of the pulse sensor within ${\pm}3^{\circ}$standard deviations. Coefficient values of variation of maximum pulse peaks extracted from the pulse waveforms were 4.692, 6.994, and 11.039 % for three channels with the highest magnitudes. It is expected that the proposed method can be helpful to develop more precise tonometry system measuring the pulse waveform on the radial artery.

• Journal of Biomedical Engineering Research
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• v.36 no.5
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• pp.191-197
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• 2015

Laser acupuncture is defined as the stimulation of traditional acupuncture points with low-intensity, nonthermal laser irradiation. Possible advantages in using laser acupuncture are the noninvasive, painless and low risks of infection treatment. The purpose of this study is to assess the effect of laser acupuncture on the quality and waveform of arterial pulses. Ten acupuncture points were stimulated repeatedly three times in 30 individuals by laser with emission in the near infrared spectral region (808 nm) using an out power and power density of 45 mW and $143W/cm^2$. The analysis of pulse quality and waveform was performed based on the measurement of arterial pressure of the left and right wrist, using a 3-dimensional blood pressure pulse analyzer. Excess-like pulse quality of subjects before laser acupuncture changed significantly to balanced pulse quality after 10, 20, and 30 minutes of laser acupuncture; coefficient of deficient or excess, $C_{DE}$, decreased significantly from 0.68 before acupuncture to 0.61, 0.55, and 0.55 after 10, 20, 30 minutes of laser acupuncture ($$p{\leq_-}0.006$$), respectively. Other pulse qualities, floating or sinking, slow or rapid, choppy or slippery did not change significantly by laser acupuncture (p > 0.05). Pulse waveform analysis showed that amplitude of main peak (systolic function or aortic compliance, $h_1$) of left and right artery pulse waves decreased significantly after 10, 20, and 30 minutes of laser acupuncture (p < 0.05). Other parameters, duration of one cardiac cycle (T), duration of rapid systolic ejection ($T_1$), duration of the systolic phase ($T_4$), and duration of the diastolic phase ($T_5$) of left and right artery pulses did not change significantly after laser acupuncture (p > 0.05).

• Proceedings of the Korean Society of Life Science Conference
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• 2008.10a
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• pp.35-35
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• 2008