• 제목/요약/키워드: pressure effects

검색결과 8,013건 처리시간 0.036초

Studies on the Effects of Piperidine Derivatives on Blood Pressure and Smooth Muscles Contractions

  • Saeed, M.;Saify, Z.S.;Gilani, A.H.;Iqbal, Z.
    • Archives of Pharmacal Research
    • /
    • 제21권4호
    • /
    • pp.370-373
    • /
    • 1998
  • Ten substituted phenacyl derivatives of 4-hydroxypiperidine were synthesized and studied for their effects on the mean arterial blood pressure (MABP) in normotensive anaesthetized rats and smooth muscles contractions of isolated rabbit jejunum. Two derivatives caused fall in blood pressure at the dose of 10-20 mg/kg and one rise in blood pressure at the dose of 20 mg/kg. Two compounds exhibited biphasic response (hypotensive followed by hypertensive) and one gave triphasic response at 10 mg/kg dose. Rest of four derivatives were found devoid of any effect on mean arterial blood pressure up to the dose of 30 mg/kg. All the derivatives except two caused relaxant effect on the spontaneous contraction of rabbit jejunum at the dose range of 0.1 -2 mg/kg.

  • PDF

가솔린 분무 거동에 미치는 분위기 조건의 영향 (Effect of Ambient Conditions on Spray Behavior of Gasoline Injector)

  • 이창식;이기형;최수천;권상일
    • 한국자동차공학회논문집
    • /
    • 제8권2호
    • /
    • pp.27-32
    • /
    • 2000
  • The main objective of this work is to investigate the effect of ambient conditions on the spray behavior and spray characteristics of high-pressure fuel injector. For this purpose, the effects of ambient pressure and temperature on the spray characteristics have been studied by applying the analysis of visualization system and phase Doppler particle analyzer. In this experiment, the visualization of spray behavior was performed under various ambient gas conditions and injection parameters such as gas temperature, ambient pressure, injection pressure of injector, and axial distance from the nozzle tip. Based on the investigation results, the spray tip penetration and spray width decrease with the increase of ambient gas pressure in the spray chamber. The effects of the spray parameters on the microscopic characteristics of gasoline spray were discussed.

  • PDF

압착무게와 압착시간이 분리대두단백 두부의 특성에 미치는 영향 (Effects of Pressure and Pressing Time on the Properties of Isolated Soy Protein-Tofu During Compressing Process)

  • 김동원;김우정
    • 한국식품영양학회지
    • /
    • 제6권4호
    • /
    • pp.301-306
    • /
    • 1993
  • Effects of pressure and pressing time of soyprotein-CaSO4 coagulates on the yield, water holding capacity and textural characteristics of SPI (soy protein isolated) tofu were investigated. The tofu was prepared by addition of CaSO4 into SPI suspension at 9$0^{\circ}C$ and then compressed. As the compressing pressure increased from 8.66g /cm2 to 49.43g /cm2, the volume yield and moisture absorbed on filter paper were decreased and the textural properties of hardness, adhesiveness, cohesiveness and gumminess were increased. Increase in hardness and gumminess were more significant at high pressure than those at low pressure.

  • PDF

실제기체 효과를 고려한 수소기체의 임계노즐 유동에 관한 연구 (Study on the Critical Nozzle Flow of Hydrogen Gas with Real Gas Effects)

  • 김재형;김희동
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2007년도 춘계학술대회B
    • /
    • pp.3003-3008
    • /
    • 2007
  • Critical nozzle has been frequently employed to measure the flow rate of various gases, but hydrogen gas, especially being at high-pressure condition, was not nearly dealt with the critical nozzle due to treatment danger. According to a few experimental data obtained recently, it was reported that the discharge coefficient of hydrogen gas through the critical nozzle exceeds unity in a specific range of Reynolds number. No detailed explanation on such an unreasonable value was made, but it was vaguely inferred as real gas effects. For the purpose of practical use of high-pressure hydrogen gas, systematic research is required to clarify the critical nozzle flow of high-pressure hydrogen gas. In the present study, a computational fluid dynamics(CFD) method has been applied to predict the critical nozzle flow of high-pressure hydrogen gas. Redlich-Kwong equation of state that take account for the forces and volume of molecules of hydrogen gas were incorporated into the axisymmetric, compressible Navier-Stokes equations. A fully implicit finite volume scheme was used to numerically solve the governing equations. The computational results were validated with some experimental data available. The results show that the coefficient of discharge coefficient is mainly influenced by the compressibility factor and the specific heat ratio, which appear more remarkable as the inlet total pressure of hydrogen gas increases.

  • PDF

임계노즐에서 발생하는 비정상유동에 관한 연구 (Study of the Unsteady Gas Flow in a Critical Nozzle)

  • 김재형;김희동;박경암
    • 유체기계공업학회:학술대회논문집
    • /
    • 유체기계공업학회 2002년도 유체기계 연구개발 발표회 논문집
    • /
    • pp.337-345
    • /
    • 2002
  • The present study addresses a computational result of unsteady gas flow through a critical nozzle. The axisymmetric, unsteady, compressible, Wavier-Stokes equations are solved using a finite volume method that makes use of the second order upwind scheme for spatial derivatives and the multi-stage Runge-Kutta integral scheme for time derivatives. The steady solutions of the governing equation system are validated with the previous experimental data to ensure that the present computational method is valid to predict the critical nozzle flows. In order to simulate the effects of back pressure fluctuations on the critical nozzle flows, an excited pressure oscillation with an amplitude and frequency is assumed downstream of the exit of the critical nozzle. The results obtained show that for low Reynolds numbers, the unsteady effects of the pressure fluctuations can propagate upstream of the throat of critical nozzle, and thus giving rise to the applicable fluctuations in mass flow rate through the critical nozzle, while for high Reynolds numbers, the pressure signals occurring at the exit of the critical nozzle do not propagate upstream beyond the nozzle throat. For very low Reynolds number, it is found that the sonic line near the throat of the critical nozzle remarkably fluctuateswith time, providing an important mechanism for pressure signals to propagate upstream of the nozzle throat, even in choked flow conditions. The present study is the first investigation to clarify the unsteady effects on the critical nozzle flows.

  • PDF

Experimental investigation of Reynolds number effects on 2D rectangular prisms with various side ratios and rounded corners

  • Wang, Xinrong;Gu, Ming
    • Wind and Structures
    • /
    • 제21권2호
    • /
    • pp.183-202
    • /
    • 2015
  • Experiments on two-dimensional rectangular prisms with various side ratios (B/D=2, 3, and 4, where B is the along-wind dimension, and D is the across-wind dimension) and rounded corners (R/D=0%, 5%, 10%, and 15%, where R is the corner radius) are reported in this study. The tests were conducted in low-turbulence uniform flow to measure the wind pressures on the surfaces of 12 models for Reynolds numbers ranging from $1.1{\times}10^5$ to $6.8{\times}10^5$. The aerodynamic force coefficients were obtained by integrating the wind pressure coefficients around the model surface. Experimental results of wind pressure distributions, aerodynamic force coefficients, and Strouhal numbers are presented for the 12 models. The mechanisms of the Reynolds number effects are revealed by analyzing the variations of wind pressure distributions. The sensitivity of aerodynamic behavior to the Reynolds number increases with increasing side ratio or rounded corner ratio for rectangular prisms. In addition, the variations of the mean pressure distributions and the pressure correlations on the side surfaces of rectangular prisms with the rounded corner ratio are analyzed at $Re=3.4{\times}10^5$.

대기압 개념학습을 위한 컴퓨터 보조수업 프로그램 개발 및 적용 (Development of a CAI Program on Atmospheric Pressure and the Effects of the CAI on Middle School Students' Science Achievement and Conceptual Change)

  • 국동식;최동하
    • 한국지구과학회지
    • /
    • 제22권2호
    • /
    • pp.89-95
    • /
    • 2001
  • 이 논문의 목적은 대기압개념에 대한 오개념을 기초하여 컴퓨터 보조수업 프로그램을 개발하여 중학교 과학과정에 적용하고 그 개념개선 효과를 조사하는 것이다. 그 결과는 다음과 같다. 1) 대기압에 대한 오개념을 확인하였고 2) 분석된 오개념을 고려한 CAI프로그램을 개발였으며 3) 학습에 적용한 결과 CAI를 적용한 학습이 전통적 학습보다 성취도와 오개념 개선에 효과적이었다.

  • PDF

입구 경계층 두께가 축류 압축기 내부 유동에 미치는 영향 (II) - 손실구조 - (Effects of the Inlet Boundary Layer Thickness on the Flow in an Axial Compressor(II) - Loss Mechanism -)

  • 최민석;박준영;백제현
    • 대한기계학회논문집B
    • /
    • 제29권8호
    • /
    • pp.956-962
    • /
    • 2005
  • A three-dimensional computation was conducted to make a study about effects of the inlet boundary layer thickness on the total pressure loss in a low-speed axial compressor operating at the design condition ($\phi=85\%$) and near stall condition($\phi=65\%$). Differences of the tip leakage flow and hub corner-stall induced by the inlet boundary layer thickness enable the loss distribution of total pressure along the span to be altered. At design condition, total pressure losses for two different inlet boundary layers are almost alike in the core flow region but the larger loss is generated at both hub and tip when the inlet boundary layer is thin. At the near stall condition, however, total pressure loss fer the thick inlet boundary layer is found to be greater than that for the thin inlet boundary layer on most of the span except the region near hub and casing. Total pressure loss is scrutinized through three major loss categories in a subsonic axial compressor such as profile loss, tip leakage loss and endwall loss using Denton's loss model, and effects of the inlet boundary layer thickness on the loss structure are analyzed in detail.

발반사마사지가 본태성 고혈압 노인의 혈압과 수면에 미치는 효과 (The Effects of Foot Reflexologic Massage on Blood Pressure and Sleep of the Elderly With Essential Hypertension)

  • 한송희;이영희
    • 성인간호학회지
    • /
    • 제17권3호
    • /
    • pp.349-357
    • /
    • 2005
  • Purpose: This study was conducted to evaluate the effects of foot reflexologic massage on blood pressure and sleep of elderly with essential hypertension. Method: This study was employed non-equivalent control group pretest-posttest quasi-experimental design. The subjects were divided into two groups: 20 elders for experimental group and 18 elders for control group. For experimental group, foot reflexologic massage was done three times at three-day intervals. The data analyzed by SPSS version 10.0 program. Result: The systolic and diastolic blood pressure after foot reflexologic massage did not show a significant difference between the two groups. In experimental group, there was a significant difference in the systolic(t=3.559, p=.001) and the diastolic blood pressure(t= 3.048, p=.004) that measured after foot reflexologic massage. There was a significant difference(t=2.665, p=.011) in sleep between the two groups. Conclusions: The results suggest that foot reflexologic massage was partially effective to reduce the degree of blood pressure and improve sleep of the elderly with essential hypertension. A follow up research is needed to compare and confirm its long-term effects.

  • PDF

Effects of Intra-abdominal Pressure with Visual Feedback on Muscle Activation of Upper Trapezius and Sternomastoid during Forced Inspiration in Individuals with Costal Respiration

  • Kim, Kwang-Su;Shin, Hwa-Kyung
    • The Journal of Korean Physical Therapy
    • /
    • 제32권2호
    • /
    • pp.75-79
    • /
    • 2020
  • Purpose: This study analyzed the immediate effects of intra-abdominal pressure with visual feedback on the muscle activation of the upper trapezius and sternomastoid during natural inspiration and forced inspiration in individuals with costal respiration. Methods: The eighteen individuals with upper costal breathing pattern participated in this study. Surface electromyography was used to analyze the muscle activity of the upper trapezius and sternomastoid during natural inspiration and forced inspiration before and after intra-abdominal pressure. Results: A significant difference in muscle activation was observed with the muscle type, inspiration type, and test session (p<0.05). The muscle activities of the sternomastoid and upper trapezius decreased significantly during forced inspiration after intra-abdominal pressure training (p<0.05). On the other hand, there was no significant difference during natural inspiration in both muscles (p>0.05). A comparison of the difference between the pre-test and post-test during forced inspiration revealed the upper trapezius to be significantly larger than the sternomastoid (p<0.05). No significant difference was noted during natural inspiration (p>0.05). Conclusion: The intra-abdominal pressure has positive effects on correcting the breathing patterns in individuals with costal respiration.