• 대한한방소아과학회지
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• 제20권2호
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• pp.101-114
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• 2006

Objective : In order to educate juveniles with proper sex education and to present advisable sexual culture among them, we researched the revelation age and duration period of secondary sex characteristics of 5th and 6th elementary student in Cheon-an, and compared them with their mother's case. Method : We did a survey among 5th and 6th grade elementary student in Cheon-an, which includes pictures presenting, different stages of breasts and pubic hair development. Results : Results show that in girls, average menarche age was 11.47 while the average of their mother's was 14.25. 3 years of decline was observed. On boys, average pubic hair development age was 11.42, similar to the average age of voice change, 11.43. Girls showed relatively earlier distribution of pubic hair manifestation age of 11.39, than in boys, which was 11.42. Concerning the sexual maturity, 99% of girls were over B2, while 43% of boys were over PH2. Almost all of the female participants manifested secondary sex characteristics, and half of them were in the stage of pubic hair development. Conclusion : We observed that the average age of manifesting secondary sex characteristic among elementary students is getting younger and especially, menarche age of young girls is significantly showing downward tendency compared to their mothers'. Sex education in elementary schools should be carried out considering the development stage of secondary sex characteristics among students.

• Gut and Liver
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• 제12권6호
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• pp.655-663
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• 2018

Background/Aims: The association between metabolic syndrome and colorectal cancer (CRC) has been suggested as one of causes for the increasing incidence of CRC, particularly in younger age groups. The present study examined whether the current age threshold (50 years) for CRC screening in Korea requires modification when considering increased metabolic syndrome. Methods: We analyzed data from the National Health Insurance Corporation database, which covers ~97% of the population in Korea. CRC risk was evaluated with stratification based on age and the presence/absence of relevant metabolic syndrome components (diabetes, dyslipidemia, and hypertension). Results: A total of 51,612,316 subjects enrolled during 2014 to 2015 were analyzed. Among them, 19.3% had diabetes, hypertension, dyslipidemia, or some combination thereof. This population had a higher incidence of CRC than did those without these conditions, and this was more prominent in subjects <40 years of age. The optimal cutoff age for detecting CRC, based on the highest Youden index, was 45 years among individuals without diabetes, dyslipidemia, and hypertension. Individuals with at least one of these components of metabolic syndrome had the highest Youden index at 62 years old, but the value was only 0.2. Resetting the cutoff age from 50 years to 45 years achieved a 6% increase in sensitivity for CRC detection among the total population. Conclusions: Starting CRC screening earlier, namely, at 45 rather than at 50 years of age, may improve secondary prevention of CRC in Korea.

• 한국발생생물학회지:발생과생식
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• 제23권3호
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• pp.213-221
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• 2019

The epididymal fat of mouse is a part of visceral fat deposit and is divided into the distal or proximal part based on its histochemical characteristics. Even though the formation of the epididymal fat pad begins before the birth, a detailed adipogenic procedure of the epididymal fat has not been revealed. The epididymal fat pad becomes enlarged and expended with age, and expressional changes of numerous genes are associated with the maturation of fat tissues. In the present research, expressional patterns of adipose tissue-related genes in the distal epididymal fat of mouse at 2, 5, 8, and 12 months of postnatal age were determined by a quantitative real-time polymerase chain reaction (PCR) analysis. The lowest transcript levels of fatty acid binding protein 4 (Fabp4), lipoprotein lipase (Lpl), delta like non-canonical Notch ligand 1 (Dlk1), peroxisome proliferator-activated receptor gamma (Pparg), leptin (Lep), adiponectin (Adipoq), and resistin (Retn) were detected at 2 months of age, except fatty acid synthase (Fasn) showing the lowest level at 5 months of age. Even though expression of Lep and Fabp4 were gradually increased until 12 months of age, significant increases of Pparg and Adipoq transcript levels were continued until 8 months of age. The transcript levels of Lpl, Rent, Dlk1, and Fasn were significantly increased at 8 months of age, compared with those at 2 months of age. The current findings suggest that the expansion of the distal epididymal fat of mouse during postnatal period would be companied with differential expression of various adipocyte-associated molecules.

• Journal of Oral Medicine and Pain
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• 제46권2호
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• pp.21-32
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• 2021

Purpose: The purpose of the present study was to investigate the correlation between age and 34 radiomorphometric parameters on panoramic radiographs, and to provide generalized linear models (GLMs) as a non-invasive, inexpensive, and accurate method to the forensic judgement of living individual's age. Methods: The study included 417 digital panoramic radiographs of Korean individuals (178 males and 239 females, mean age: 32.57±17.81 years). Considering the skeletal differences between the sexes, GLMs were obtained separately according to sex, as well as across the total sample. For statistical analysis and to predict the accuracy of the new GLMs, root mean squared error (RMSE) and adjusted R-squared (R²) were calculated. Results: The adjusted R²-values of the developed GLMs in the total sample, and male and female groups were 0.623, 0.637, and 0.660, respectively (p<0.001), while the allowable RMSE values were 8.80, 8.42, and 8.53 years, respectively. In the GLM of the total sample, the most influential predictor of greater age was decreased pulp area in the #36 first molar (beta=-26.52; p<0.01), followed by the presence of periodontitis (beta=10.24; p<0.01). In males, the most influential factor was the presence of periodontitis (beta=9.20; p<0.05), followed by the number of full veneer crowns (beta=2.19; p<0.001). In females, the most influential predictor was the presence of periodontitis (beta=18.10; p<0.001), followed by the tooth area of the #16 first molar (beta=-11.57; p<0.001). Conclusions: We established acceptable GLM for each sex and found out the predictors necessary to age estimation which can be easily found in panoramic radiographs. Our study provides reference that parameters such as the area of tooth and pulp, the number of teeth treated, and the presence of periodontitis should be considered in estimating age.

• 대한소아치과학회지
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• 제51권2호
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• pp.185-196
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• 2024

Temporomandibular joint disorders (TMDs) can occur at any age, including childhood and adolescence, and pain-related TMDs can affect growth and quality of life. In the present study, recent trends in the diagnosis and treatment of TMDs in children and adolescents were analyzed over a 10-year period. Using 10 years of data from the Health Insurance Review and Assessment Service (HIRA) and Jeonbuk National University (JBNU) Dental Hospital, patients between 0 and 19 years of age diagnosed with K07.6 (temporomandibular joint disorders) were analyzed by 5-year bins. Both datasets indicated a higher prevalence in females (1.2-fold in HIRA, 1.5-fold in JBNU) and in ages 15 to 19 years (72.1% in HIRA, 74.7% in JBNU). HIRA reported a 42.3% increase in prevalence per 100,000 people, from 651.4 in 2011 to 927.0 in 2020. JBNU reported K07.66 (masticatory muscle disorders) as the most common diagnosis in subjects under 10 years of age and K07.60 (internal derangement of temporomandibular joint) in those over 10 years of age. In addition, both were treated mainly by a combination of physical therapy and medication, and the treatment rate increased in accordance with age. Because TMDs can affect various structures in the orofacial region and cause pain that tends to differ with age, an early and specific diagnosis appropriate for age is important for treatment. Therefore, pediatric dentists need to promptly recognize TMDs in children and adolescents and consult with specialists as the prevalence increases.

• JSTS:Journal of Semiconductor Technology and Science
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• 제2권2호
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• pp.102-110
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• 2002

In this paper, we present the fabrication of tunable capacitors and 3-dimensional inductors. This work was related to fabricated 3-dimensional device for need of micro device in developing new intelligence age. This device was fabricated by electroplating used electroplating PR and high-vacuum evaporation of metal. Fabricated micro-inductor is consisted of air-bridge on electroplating rod and electroplated core. Micro-capacitor is consisted of thin metal membrane and electroplated core. Electroplating material is used Cu metal solvent. Air-gap between metal-layers function as almost perfect isolation layer. The most advantage of our micro-inductor and micro-capacitor compared to present device is a possibility that can fabricate on RF MEMS(microelectro-mechanical systems) application with high performance and various function. In this paper, we present the fabrication of tunable capacitors and 3-dimensional inductors. This work was related to fabricated 3-dimensional device for need of micro-device in developing new intelligence age. This device was fabricated by electroplating used electroplating PR and high-vacuum evaporation of metal. Fabricated micro-inductor is consisted of air-bridge on electroplating rod and electroplated core. Micro-capacitor is consisted of thin metal membrane and electroplated core. Electroplating material is used Cu metal solvent. Air-gap between metal-layers function as almost perfect isolation layer. The most advantage of our micro-inductor and micro-capacitor compared to present device is a possibility that can fabricate on RF MEMS application with high performance and various functions.

• Asian-Australasian Journal of Animal Sciences
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• 제17권12호
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• pp.1689-1694
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• 2004

This study was conducted to develop a novel adjustment factors for 305 days using 138,103 lactation records and 1,770,764 daily records, which were based on environmental circumstances such as herd year, season, age at calving, dry period and lactating stages. The present study showed that the change of persistency of cows at the first parity from total lactacting characteristics was slowly processed, while it was rapidly changed in cows at the second parity stage. Particularly, there was an outstanding difference between the first and second parity cows. Milk yield and composition increased as the age at calving was increased. In addition, milk yield and composition were higher at the first parity on fall compared with others, and those were higher at the more than second parity on fall and winter compared with other parity stages and seasons. The cow of dry group was included into lactating records of more than second parity stage. The data indicated that optimal results arose from 45-70 days of dry period. Milk yield was decreased when dry period was longer or shorter than 45-70 days. The lactating days were divided into 17, 28 and 38 stages to compare the multiplicative correction factors. The factor was effective at 28 stages on the first parity. The total correlation coefficients were 0.93832, 0.95058 and 0.95076 at the present correction factor, 17 stage and 28 stage, respectively. At second parity, the factor was higher in dry group 1 and 3 at 17 stage, and it was higher in dry group 2 at 28 stage compared with others. Therefore, the present study showed that the percent squared bias (PSB), which was calculated from the novel correction factor, was better than previously used correction factors. Also, the present study indicated that the bias of the novel correction factor was improved, and this factor could be more accurate compared with others.

• Journal of Oral Medicine and Pain
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• 제38권3호
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• pp.235-246
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• 2013

법치의학적 연령 감정은 개인 식별에 있어 중요한 역할을 한다. 본 연구는 한국 연령 감정 대상자들의 사회적 특성을 분석하는 것을 목적으로 한다. 2012년 3월부터 2013년 3월까지 경북대학교 치과병원 구강내과에 연령 감정을 의뢰한 대상자들에게 설문조사를 실시하였다.결과는 다음과 같다: 1. 성별 분포에서, 남성(42.86%)보다 여성(57.14%)이 더 많았다. 50대와 60대 이상의 고령자가 대다수였으며(89.28%), 40대 아래로는 한 명의 의뢰인도 없었다. 의뢰인들의 대부분이 초등학교 졸업 이하의 학력을 가지고 있었다(69.64%). 2. 호적 상 연령과 의뢰인이 주장하는 연령 간의 차이가 나게 된 가장 큰 이유로는 가족 및 친척의 실수로 인한 것이 가장 많았다(80.36%). 연령 감정을 통해 얻고자 하는 목적은 사회 복지 혜택(62.50%), 사회적 인관 관계 문제(12.50%), 단지 바른 나이를 찾기 위해서(10.71%), 직업과 관련한 문제(8.93%) 순이었다. 3. 연령 감정을 하기 위해 치과(구강내과)를 찾게 된 경로로는 관공서의 비중이 높았으며(48.21%), 친구나 지인(21.43%), 대중매체(14.29%), 병의원(10.71%) 등을 통한 경로가 뒤를 이었다. 법치의학적 연령 감정에 대한 의뢰인들의 이해도는 10점 만점에 7.03점으로 높은 수준이었다. 절반 이상의 의뢰인들에게서 현재의 연령 감정 비용에 대해 만족하는 것으로 나타났다. 4. 법치의학적 연령 감정을 통해 감정된 연령과 의뢰인들이 주장하는 연령 간에는 57.14%의 근접도를 보였다. 1년 간 조사한 연령 감정 대상자들의 23.53%가 법적으로 연령 정정을 하게 되었다.

• 한국가금학회지
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• 제22권2호
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• pp.67-75
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• 1995

The present study was conducted to estimate production performances, heritabilities, and genetic and phenotypic correlations on several economic traits in Korean native chicken. Data analyzed were the records of 1,096 pullets produced from 180 dams and 26 sires of Korean native chicken from April 19,1994 to February 26, 1995. Results obtained are surnmarized as follows: 1. The body weights(X${\pm}$SD) at 2, 8, 14 and 20 weeks of age were 114${\pm}$13, 690${\pm}$114, 1,163${\pm}$238, and 1,687${\pm}$349g, respectively. The age at first egg was 165.95${\pm}$14.54 days, and the number of eggs produced by 300 days of age were 70.78i23.47. The egg weights of the first egg and at 300 days of age were 37.88${\pm}$3.73 and 50.97${\pm}$3.69 g, respectively. 2. The heritability estimates of body weight based on the variance of sires, dams and combined components were 0.149, 0.298, and 0.224 at 8 weeks of age: 0.162, 0.220, and 0.192 at 20 weeks of age, respectively. 3. The heritability estimates of egg production traits based on the variance of sires, dams, and combined components were 0.232, 0.504, and 0.368 for age at first egg; 0.113, 0.172, and 0.143 for number of egg production by 300 days of age: 0.174, 0.352, and 0.236 for egg weight at 300 days of age, respectively. 4. The genetic correlation coefficients of some economic traits were as follows: between body weight and age at first egg, -0.354~-0.048; between body weight and number of egg production, -0.279~ -0.002; between body weight and egg weight, 0.338~0.977; between age at first egg and number of egg production, -0.791; between age at first egg and egg weight, 0.009~0.178; between number of egg production and egg weight, -0.572~ -0.256, respectively. 5. The phenotypic correlation coefficients of some economic traits were as follows: between body weight and age at first egg, -0.179~-0.006 between body weight and number of egg production, -0.045~0.074: between body weight and egg weight, 0.229~0.404: between age at first egg and number of egg production, -0.588: between age at first egg and egg weight, -0.029~0.597: between number of egg production and egg weight, -0.376~0. 019, respectively.

• 한국치위생학회지
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• 제19권5호
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• pp.689-698
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• 2019

Objectives: The study aimed to investigate the relationship between depression and number of present teeth in Korean elderly individuals. Methods: Data for this cross-sectional survey was obtained from the records of the sixth Korea National Health and Nutrition Examination Survey (KNHANES). The subjects were 1,199 Korean elderly individuals above 65 years of age. The survey and examination data were used for the independent variables. The KNHANES included health status, nutrition survey, and oral examination. $x^2-test$ was performed to identify the characteristics of depression and number of teeth present according to the characteristics of the study subjects. Logistic regression analysis was also performed to identify the relationship between depression and number of teeth present. The statistical significance level wa sset at 0.05. Results: The prevalence of depression in the subjects was 14.8%. There were statistically significant differences in the prevalence of depression, depending on gender (p<0.001), education level (p=0.001), income (p=0.001), spouse status (p<0.001), and alcohol consumption (p=0.020). The association between depression and the number of teeth present showed statistically significant difference after adjustment (p=0.040). Conclusions: Depression in elderly individuals was closely related to the number of teeth present. Therefore, public health policies for improving oral health should be established to prevent depression.