• Parasites, Hosts and Diseases
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• 제47권2호
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• pp.179-183
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• 2009

Prevalence rates reported for malaria in pregnancy in Nigeria vary considerably. The accuracy of results of malaria diagnosis is dependent on training, experience, and motivation of the microscopist as well as the laboratory facility available. Results of training programmes on malaria microscopy have shown low levels of sensitivity and specificity of those involved in malaria diagnosis routinely and for research. This study was done to ascertain the true prevalence of malaria in pregnancy in Lagos, South-West Nigeria. A total of 1,084 pregnant women were recruited into this study. Blood smears stained with Giemsa were used for malaria diagnosis by light microscopy. Malaria infection during pregnancy presents mostly as asymptomatic infection. The prevalence of malaria in this population was 7.7% (95% confidence interval; 6.2-9.4%). Factors identified to increase the risk of malaria infection include young maternal age (<20 years), and gravidity (primigravida). In conclusion, this study exposes the over-diagnosis of malaria in pregnancy and the need for training and retraining of laboratory staffs as well as establishing the malaria diagnosis quality assurance programme to ensure the accuracy of malaria microscopy results at all levels.

• Parasites, Hosts and Diseases
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• 제43권2호
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• pp.69-71
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• 2005

This study was performed in order to evaluate the sero-epidemiological status of toxoplasmosis in pregnant Korean women. Among 5,175 sera and 750 amniotic fluid samples obtained from pregnant women, 41 serum samples $(0.79\%)\;and\;10 (1.33\%)$ amniotic fluid samples tested positive for IgG antibodies by ELISA. Fifty one cases showing a score more than 0.25 on ELISA were tested for PCR reaction against the SAG1 gene. Only one case of the 51 ELISA positive cases exhibited a positive reaction on all tests. This case had a history of acute nephropyelitis during early pregnancy, but fortunately, had delivered a phenotypically healthy baby. In this study, the seroprevalence of toxoplasmosis in pregnant women was found to be comparatively low, consistent with previous reports from Korea. However our trials, performed with a variety of diagnostic tools, were considered to be useful for the precise diagnosis of congenital toxoplasmosis.

• Journal of Korean Biological Nursing Science
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• 제19권4호
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• pp.258-265
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• 2017

Purpose: The purpose of this study was to examine the exercise patterns and the factors affecting exercise duration in pregnant women. Methods: The survey was conducted to assess walking and exercise duration in 146 pregnant participants, who live in Gyeongsang area. Data was analyzed with descriptive statistics, t-test, ANOVA and regression using the SPSS Win 23.0 program. Results: The average age of the participants was 31 years, and more than 87% of them were primigravida. The differences in the mean walking duration, the daily exercise duration, and the exercise days of participants before and during pregnancy were not statistically significant, but the exercise duration during pregnancy was decreased compared to that before pregnancy. The factors affecting weekly exercise duration were diagnosis of gestational diabetes mellitus, concern about weight gain during pregnancy, and monthly income. Conclusion: The results of this study show that development of an educational program to teach proper exercise practices during pregnancy is recommended.

• 대한수의학회지
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• 제32권2호
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• pp.259-265
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• 1992

A study was conducted to improve the reproductive performance of Korean native goats. The length of estrous cycle and plasma progesterone concentrations during each cycles were determined by both radioimmunoassay and estrus behaviours, and the results were used in the early pregnancy diagnosis. The estrous cycles were classified into the short(l8 days or shorter, average 16.7 days), normal(19 to 22 days, average 20.9 days) and long(23 days and longer, average 23.8 days)cycle. The average length of the 19 estrous cycles was 20.8 days. Plasma progesterone concentrations in 12 normal cycles were the lowest(0.10 ng/ml) at estrus, remained high from 6 to 16 days(range : 4.43~7.93 ng/ml) and drastically decreased thereafter to reach minimal concentrations at the next estrus. Plasma progesterone concentrations were measured for early pregnancy diagnosis at 0, 10 and 20 days after mating in the 12 Korean native goats. Plasma progesterone concentrations in the pregnant goats at 20 days after mating were significantly higher than in the non-pregnant goats(p<0.001). Of the 12 goats, 10 were confirmed pregnancy by both progesterone concentrations and kidding. The accuracy of the pregnancy diagnosis based on plasma progesterone concentrations was 100% for positive as well as for negative.

• 한국방사선학회논문지
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• 제6권6호
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• pp.441-445
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• 2012

다양한 질환이 발생 될 수 있는 임신중에 산모의 건강상태를 검사하기 위해서는 임산부의 X-ray 흉부촬영이 필수적으로 이루어지게 된다. 따라서 임산부의 X-ray 흉부촬영에 관한 의료용 방사선의 사용은 기본적인 검사로 사용되어지고 있다. 따라서 임신초기인 착상기 부터 태아의 각종 장기 형성 및 기관 형성기까지 대부분의 임신기간은 방사선의 직접적인 차폐가 요구되어진다. 하지만 현재 사용되고 있는 납치마는 임산부가 직접 손으로 잡고 있고 는 불편함으로 인한 산모의 정확한 X-ray 흉부촬영 자세가 이루어지지 않고 있는 실정이다 또한 이러한 결과로 인해 산모의 X-ray 흉부촬영 영상이 폐첨부와 견갑골이 자주 겹쳐 흉부영상이 질적으로 저하되는 현상을 가져다 주고 있다. 이러한 문제점을 극복하기 위해 산모용 납치마를 제작하였다. 결과적으로 새로 디자인한 산모용 납치마는 산모의 X-ray흉부 촬영시 편한 자세를 유지 할 수 있게 해주었다. 아울러 산모가 정확한 자세를 취 할 수 있게 되었다. 더 나아가서 산모의 X-ray흉부 촬영시 견갑골과 폐첨부가 겹치는 현상을 최소화 해주어서 산모의 흉부촬영 영상에 최적화된 이미지를 제공 할 수 있게 해 주었다.

• Advances in nano research
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• 제17권3호
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• pp.213-219
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• 2024

Nanotechnology is one of the critical factors involved in enhancing the sensitivity of serum biomarker detection. To explore the relationship between serum APN, Cystatin C and MMP-9 levels in patients with hypertension during pregnancy and the severity and prognosis of the disease. A total of 75 cases of hypertensive disorder complicating pregnancy (HDCP) patients who were admitted to the hospital from February 5, 2023 to May 9, 2024, were selected as the study group, and 70 healthy pregnant women who were in the same gestational week were selected as the control group. The serum APN, MMP-9 and Cys C levels of pregnant women and HDCP patients with different disease severity were compared between the two groups, and the receiver characteristic curve (ROC) was used to analyze its diagnostic value. The serum APN, MMP-9 and Cys C levels of HDCP patients with different prognosis were compared, and the factors affecting the prognosis of patients were analyzed by Logistic regression. Nanoparticles could aslo enable the sensitive detection and quantification of APN, Cystatin C, and MMP-9 in serum samples, thus increasing the accuracy of the study. The serum MMP-9 and Cys C levels of pregnant women in the study group were significantly increased, and the APN level was significantly decreased (P<0.05). Serum MMP-9 and Cys C levels in patients with pregnancy-induced hypertension, mild preeclampsia, and severe preeclampsia gradually increased (r=0.768, 0.766; P<0.001), and APN levels gradually decreased (r=-0.748, P< 0.001). In the diagnosis of patients with HDCP, the sensitivity, specificity and AUC of APN single diagnosis were 70.00%, 82.67% and 9.848 respectively. The sensitivity, specificity and AUC of MMP-9 single diagnosis were 82.86%, 74.67% and 298.300 respectively. The sensitivity, specificity and AUC of Cys C single diagnosis were 80.00%, 74.67% and 1.301 respectively. There were significant differences in age, BMI, parity, dysthymia, disease severity, APN, MMP-9 and Cys between patients with poor prognosis of HDCP and patients with good prognosis of HDCP (P<0.001). The patient's age, BMI, disease severity, APN, MMP-9 and Cys Cwere all related to HDCP. They were related risk factors of HDCP (P<0.05).

• 대한수의학회지
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• 제31권4호
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• pp.529-534
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• 1991

Plasma progesterone concentrations were measured from 97 Che-ju native mares throughout the estrous cycle, Day 20 to 23, 5 to7 months of pregnancy, and gestation period (<1 to 7 months) using the radioimmunoassay techniques for pregnancy diagnosis. Plasma progesterone concentrations during the estrous cycle were the lowest (<1.0ng/ml) at estrus, remained high from 9 to 18 days (3.7~7.6ng/ml) and drastically decreased thereafter to reach minimal concentrations at the next estrus. Plasma progesterone concentrations at Day 21 to 24 were a significantly different between in pregnant mares (>5.7ng/ml) and in non-pregnant mares (<1.0ng/ml). The accuracy of the pregnancy diagnosis based on plasma progesterone concentrations at Day 20 to 23 was 86.7% for positive and 100% for negative, whereas on 5 to 7 months was 66.7% for positive and 71.0% for negative, respectively. Plasma progesterone concentrations during the gestation period(1 to 7 months) increased after 1 month of pregnancy, with peak concentrations(>8.0ng/ml) occurring between 60 to 100 days of pregnancy, and decreased below 1.7ng/ml after 6 months of pregnancy.

• 대한의생명과학회지
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• 제9권1호
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• pp.29-36
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• 2003

Progesterone levels in the blood plasma or skim milk of cows are considered to be very useful indicator fur the detection of estrus cycle and early pregnancy diagnosis. During 13 to 14 days after estrus the level of progesterone in plasma or skim milk were not different between the inseminated arid non-inseminated cows. In the pregnant cows the peak level of progesterone reached on 14th day after artificial insemination (AI), but in the absence of conceptus the level declines after the 14th day slowly, and then very rapidly towards the basal level after the 17th day. This low level persists about 4 days, including those of estrus and ovulation a highly characteristic pattern which differs so markedly from that in the pregnant cows. Progesterone levels in blood plasma or skim milk can provided a reliable diagnosis of early pregnancy and monitoring ovarian activity in cows. The mean $\pm$ standard deviation of milk urea nitrogen(MUN) and protein concentration in the cows at 9 herds were 17.7$\pm$2.35 mg/dL and 3.2$\pm$0.17%, respectively. The days of nonpregnant after parturition was shorter in the cows in which the lower level of MUN than higher level of MUN concentration.

• Child Health Nursing Research
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• 제18권3호
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• pp.150-156
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• 2012

Purpose: The main purposes of this study were to assess maternal-fetal attachment (MFA) of the expectant mothers of a fetus with a prenatal diagnosis of congenital heart disease (CHD) and to identify factors associated with MFA. Methods: The methodology was a cross sectional survey study using a self-administered questionnaire. Thirty pregnant women carrying a fetus with a prenatal diagnosis of CHD and 30 pregnant women with a normal fetus were enrolled in this study. The MFA Scale and PPS (The Prenatal Psychosocial Profile) were used to collect data. Data were analyzed using SPSS 20.0 Window version. Descriptive statistics, $X^2$-test and t-test were used to compare the two groups. The factors associated with MFA were identified by multiple regression analysis. Results: There was no significant difference between the two groups in MFA and social support from spouse was the only variable showing a significant difference. The model from the multiple regression analysis explained 33.8% of MFA for both groups. Conclusion: MFA of expectant mothers with a prenatal diagnosis of CHD and of mothers with a normal fetus were not significantly different. It is important that health care providers encourage expectant fathers to support the expectant mothers to increase MFA.

• 여성건강간호학회지
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• 제29권4호
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• pp.302-316
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• 2023

Purpose: This study aimed to develop and validate a structural model for the quality of life (QoL) among high-risk pregnant women, based on Roy's adaptation model. Methods: This cross-sectional study collected data from 333 first-time mothers diagnosed with a high-risk pregnancy in two obstetrics and gynecology clinics in Cheonan, Korea, or participating in an online community, between October 20, 2021 and February 20, 2022. Structured questionnaires measured QoL, contextual stimuli (uncertainty), coping (adaptive or maladaptive), and adaptation mode (fatigue, state anxiety, antenatal depression, maternal identity, and marital adjustment). Results: The mean age of the respondents was 35.29±3.72 years, ranging from 26 to 45 years. The most common high-risk pregnancy diagnosis was gestational diabetes (26.1%). followed by preterm labor (21.6%). QoL was higher than average (18.63±3.80). Above-moderate mean scores were obtained for all domains (psychological/baby, 19.03; socioeconomic, 19.00; relational/spouse-partner, 20.99; relational/family-friends, 19.18; and health and functioning, 16.18). The final model explained 51% of variance in QoL in high-risk pregnant women, with acceptable overall model fit. Adaptation mode (β=-.81, p=.034) and maladaptive coping (β=.46 p=.043) directly affected QoL, and uncertainty (β=-. 21, p=.004), adaptive coping (β=.36 p=.026), and maladaptive coping (β=-.56 p=.023) indirectly affected QoL. Conclusion: It is essential to develop nursing interventions aimed at enhancing appropriate coping strategies to improve QoL in high-risk pregnant women. By reinforcing adaptive coping strategies and mitigating maladaptive coping, these interventions can contribute to better maternal and fetal outcomes and improve the overall well-being of high-risk pregnant women.