• Journal of Environmental Health Sciences
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• v.50 no.2
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• pp.113-124
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• 2024

Background: The increasing need to minimize animal testing has sparked interest in alternative methods with more humane, cost-effective, and time-saving attributes. In particular, in silico-based computational toxicology is gaining prominence. Adverse outcome pathway (AOP) is a biological map depicting toxicological mechanisms, composed of molecular initiating events (MIEs), key events (KEs), and adverse outcomes (AOs). To understand toxicological mechanisms, predictive models are essential for AOP components in computational toxicology, including molecular structures. Objectives: This study reviewed the literature and investigated previous research cases related to AOP and in silico methodologies. We describe the results obtained from the analysis, including predictive techniques and approaches that can be used for future in silico-based alternative methods to animal testing using AOP. Methods: We analyzed in silico methods and databases used in the literature to identify trends in research on in silico prediction models. Results: We reviewed 26 studies related to AOP and in silico methodologies. The ToxCast/Tox21 database was commonly used for toxicity studies, and MIE was the most frequently used predictive factor among the AOP components. Machine learning was most widely used among prediction techniques, and various in silico methods, such as deep learning, molecular docking, and molecular dynamics, were also utilized. Conclusions: We analyzed the current research trends regarding in silico-based alternative methods for animal testing using AOPs. Developing predictive techniques that reflect toxicological mechanisms will be essential to replace animal testing with in silico methods. In the future, since the applicability of various predictive techniques is increasing, it will be necessary to continue monitoring the trend of predictive techniques and in silico-based approaches.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.49 no.7
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• pp.488-493
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• 2000

In this paper, a predictive current control of 12-pulse parallel connected dual converter system without interphase reactors(IPR) is presented. Firstly, the characteristics of system without IPR are analyzed and compared with that of system with IPR. And the predictive current control of this system is discussed. Finally the validity of the presented system and the excellence of the predictive current control response is proved through the simulation results and experimental results.

• International journal of advanced smart convergence
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• v.12 no.3
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• pp.221-232
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• 2023

Recently, due to the expansion of the logistics industry, demand for logistics automation equipment is increasing. The modern logistics industry is a high-tech industry that combines various technologies. In general, as various technologies are grafted, the complexity of the system increases, and the occurrence rate of defects and failures also increases. As such, it is time for a predictive maintenance model specialized for logistics automation equipment. In this paper, in order to secure the operational reliability of the ICT/Cold-Chain Unmanned Storage, a predictive maintenance system was implemented based on the LSTM model. In this paper, a server for data management, such as collection and monitoring, and an analysis server that notifies the monitoring server through data-based failure and defect analysis are separately distinguished. The predictive maintenance platform presented in this paper works by collecting data and receiving data based on RabbitMQ, loading data in an InMemory method using Redis, and managing snapshot data DB in real time. The predictive maintenance platform can contribute to securing reliability by identifying potential failures and defects that may occur in the operation of the ICT/Cold-Chain Unmanned Storage in the future.

• International Journal of Computer Science & Network Security
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• v.24 no.1
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• pp.215-225
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• 2024

Predictive maintenance has been considered fundamental in the industrial applications in the last few years. It contributes to improve reliability, availability, and maintainability of the systems and to avoid breakdowns. These breakdowns could potentially lead to system shutdowns and to decrease the production efficiency of the manufacturing plants. The present article aims to study how predictive maintenance could be planed into the production scheduling, through a systematic review of literature. . The review includes the research articles published in international journals indexed in the Scopus database. 165 research articles were included in the search using #predictive maintenance# AND #production scheduling#. Press articles, conference and non-English papers are not considered in this study. After careful evaluation of each study for its purpose and scope, 50 research articles are selected for this review by following the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA) statement. A benchmarking of predictive maintenance methods was used to understand the parameters that contributed to improve the production scheduling. The results of the comparative analysis highlight that artificial intelligence is a promising tool to anticipate breakdowns. An additional impression of this study is that each equipment has its own parameters that have to be collected, monitored and analyzed.

• The Journal of Fisheries Business Administration
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• v.54 no.1
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• pp.37-49
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• 2023

Climate change is a major global problem. Oysters, one of the most representative farmed fish in Korea, are attracting attention as candidates for blue carbon, an alternative to carbon neutrality. This study is analyzed by the SSP scenarios to determine the impact of oyster aquaculture production according to climate change. Based on the analysis, future productions of oysters are predicted by the SSP scenario. Significant differences by the SSP scenario are confirmed through predictive power tests among scenarios. Regression analysis was conducted from January 2001 to December 2014. As a result of the analysis, water temperature, water temperature quadratic term, salinity, salinity quadratic term, and month × water temperature cross term were estimated as significant variables. Oyster production which is predicted by the SSP scenario based on the significant variables from 2015 to 2022 was compared with actual production. The model with the highest predictive power was selected by RMSE and MAPE criteria. The predictive power was compared with the MDM test to determine which model was superior. As a result, based on RMSE and MAPE, the SSP1-2.6 scenario was selected as the best model and the SSP1-2.6, SSP2-4.5, and SSP3-7.0 scenarios all showed the same predictive power based on the MDM test. In conculusion, this study predicted oyster aquaculture production by 2030, not the distant future, due to the short duration of the analytical model. This study was found that oyster aquaculture production increased in all scenarios and there was no significant difference in predictive power by the SSP scenario.

• Journal of the Korean Society for Advanced Composite Structures
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• v.5 no.4
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• pp.11-17
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• 2014

A progressive failure analysis procedure for composite laminates is completed in here. An anisotropic plastic constitutive model for fiber-reinforced composite material is implemented into computer program for a predictive analysis procedure of composite laminates. Also, in order to describe material behavior beyond the initial yield, the anisotropic work-hardening model and subsequent yield surface are implemented into a computer code, which is Predictive Analysis for Composite Structures (PACS). The accuracy and efficiency of the anisotropic plastic constitutive model and the computer program PACS are verified by solving a number of various fiber-reinforced composite laminates with and without geometric discontinuity. The comparisons of the numerical results to the experimental and other numerical results available in the literature indicate the validity and efficiency of the developed model.

• 한국태양에너지학회:학술대회논문집
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• 2008.11a
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• pp.288-293
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• 2008

A predictive model of wind speed in the wind farm has very important meanings. This paper presents an estimation model of wind speed based on time series analysis using the observed wind data at Hangyeong Wind Farm in Jeju island, and verification of the predictive model. In case of Hangyeong Wind Farm and Haengwon Wind Farm, The ARIMA(Autoregressive Integrated Moving Average) predictive model was appropriate, and the wind speed estimation model was developed by means of parametric estimation using Maximum likelihood Estimation.

• Tuberculosis and Respiratory Diseases
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• v.75 no.5
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• pp.181-187
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• 2013

The emergence of new therapeutic agents for non-small cell lung cancer (NSCLC) implies that histologic subtyping and molecular predictive testing are now essential for therapeutic decisions. Histologic subtype predicts the efficacy and toxicity of some treatment agents, as do genetic alterations, which can be important predictive factors in treatment selection. Molecular markers, such as epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) rearrangement, are the best predictors of response to specific tyrosine kinase inhibitor treatment agents. As the majority of patients with NSCLC present with unresectable disease, it is therefore crucial to optimize the use of tissue samples for diagnostic and predictive examinations, particularly for small biopsy and cytology specimens. Therefore, each institution needs to develop a diagnostic approach requiring close communication between the pulmonologist, radiologist, pathologist, and oncologist in order to preserve sufficient biopsy materials for molecular analysis as well as to ensure rapid diagnosis. Currently, personalized medicine in NSCLC is based on the histologic subtype and molecular status. This review summarizes strategies for tissue acquisition, histologic subtyping and molecular analysis for predictive testing in NSCLC.

• Journal of Intelligence and Information Systems
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• v.1 no.2
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• pp.1-16
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• 1995

The field of human judgment and decision making provides useful methodologies for examining the human decision making process and substantive results. One of the methodologies is a lens model analysis which can examine valid nonlinearity in the human decision making process. Using the method, valid nonlinearity in human decision behavior can be successfully detected. Two linear(statistical) models of human experts and two nonlinear models of human experts are compared in terms of predictive accuracy (predictive validity). The results indicate that nonlinear models can capture factors(valid nonlinearity) that contribute to the expert's predictive accuracy, but not factors (inconsistency) that detract from their predictive accuracy. Then, it is argued that nonlinear models cab be more accurate than linear models, or as accurate as human experts, especially when human experts employ valid nonlinear strategies in decision making.

• Journal of Korean Elementary Science Education
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• v.26 no.5
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• pp.551-557
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• 2007

The purpose of this study was to examine the questions in the 'Matter' units of elementary science textbooks under the 7th curriculum. For the analysis, a total of 338 questions were extracted from 15 units. Six criteria (recalling, recognizing, predictive, applied, divergent, and evaluative question) were reconstructed for textbook question analysis based on Blosser(1973)'s question category system for science. The results were as follows. First, there were more closed (recalling, recognizing, predictive, or applied) questions (72.2%) than open (divergent or evaluative) questions (27.8%) in elementary science textbooks. Second, cognitive-memory (recalling or recognizing) question type was the most frequently asked in all grade levels. Open (divergent or evaluative) questions increased according to grade level whereas convergent (predictive or applied) questions decreased. Third, question types were applied based on the characteristics of each unit rather than on children's developmental characteristics. Educational implications were discussed based on the results.