• Bulletin of the Korean Chemical Society
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• 제32권2호
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• pp.645-650
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• 2011

The 3D-QSAR study of 2-arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors was performed by comparative molecular field analysis (CoMFA), CoMFA region focusing (CoMFA-RF) for optimizing the region for the final PLS analysis, and comparative molecular similarity indices analysis (CoMSIA) methods to determine the factors required for the activity of these compounds. The best orientation was searched by all-orientation search strategy using AOS, to minimize the effect of the initial orientation of the structures. The predictive ability of CoMFARF and CoMSIA were determined using a test set of twelve compounds giving predictive correlation coefficients of 0.886, and 0.754 respectively indicating good predictive power. Further, the robustness and sensitivity to chance correlation of the models were verified by bootstrapping and progressive scrambling analyses respectively. Based upon the information derived from CoMFA(RF) and CoMSIA, identified some key features that may be used to design new inhibitors for cholesteryl ester transfer protein.

• The Journal of Asian Finance, Economics and Business
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• 제7권5호
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• pp.31-40
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• 2020

This study investigates whether other comprehensive income (OCI) reported in the statement of comprehensive income (one of the main financial statements after the adoption of K-IFRS) predicts a firm's future performance. Using the quarterly data of Korean listed companies, we examine the association between OCI estimates and future earnings. First of all, we find that OCI is positively associated with earnings in both 1- and 2-quarter ahead, supporting the predictive value of OCI. When we break down OCI into its individual components, our results suggest that the net unrealized gains/losses on available-for-sale (AFS) investment securities are positively associated with future earnings, while the other components (e.g., net unrealized gains/losses on valuation of cash flow hedge derivatives) present insignificant results. In addition, we investigate whether the reliability in OCI estimates enhances the predictive value of OCI to predict future performance. We find that the predictive ability of OCI, in particular the net unrealized gains/losses on available-for-sale (AFS) investment securities, becomes more pronounced when firms are audited by the Big 4 audit firms. Overall, our study suggests that information content embedded in OCI can provide decision-useful information that is helpful for the prediction of future firm performance.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1991년도 하계학술대회 논문집
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• pp.564-567
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• 1991

In this paper a predictive current control strategy is adopted in the D.C motor drive using dual converter. It is a kind of feedforward control working without overshoot within very short settling time. The difference to the well-known PI current control lies in considering the computer's ability of pre-calcurating the converter's behavior. By simulation it is shown that the predictive current control solve the problems of optimal PI current control, such as overshoot and settling time.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1991년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 22-24 Oct. 1991
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• pp.99-104
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• 1991

An adaptive predictive control method for SISO and MIMO plants is proposed. In this method, future predictions of process output based on a bilinear CARIMA model are used to calculate the control input. Also, a classical recursive adaptation algorithm, equation error method, is used to decrease the uncertainty of the process model. As a result of the application on distillation process, the ability of the set-point tracking and the disturbance rejection is acceptable to apply to the industrial distillation processes.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1990년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 26-27 Oct. 1990
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• pp.225-228
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• 1990

The major difficulty in distillation column control lies in executing the set point tracking and the disturbance rejection, because of continuous changes in model order and dead time. For that, generalized predictive control(GPC) was applied to distillation column control. Recursive least square method was used to adjust the changes of model order and dead time. Quadratic progamming(QP) was used to solve the constraint problems in control action and the rate of control action. As a result of the simulation on the dynamic simulator(SPEEDUP) and the experiment on pilot plant, the ability of the set point tracking and the disturbance rejection was acceptable to apply to the real distillation column.

• 통합자연과학논문집
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• 제4권4호
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• pp.266-272
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• 2011

Focal adhesion kinase (FAK) is a potential target for the treatment of primary cancers as well as prevention of tumor metastasis. To understand the structural and chemical features of FAK inhibitors, we report comparative molecular field analysis (CoMFA) for the series of 7H-pyrrolo(2,3-d)pyrimidines. The CoMFA models showed good correlation between the actual and predicted values for training set molecules. Our results indicated the ligand-based alignment has produced better statistical results for CoMFA ($q^2$ = 0.505, $r^2$ = 0.950). Both models were validated using test set compounds, and gave good predictive values of 0.537. The statistical parameters from the generated 3D-QSAR models were indicated that the data are well fitted and have high predictive ability. The contour map from 3D-QSAR models explains nicely the structure-activity relationships of FAK inhibitors and our results would give proper guidelines to further enhance the activity of novel inhibitors.

• Food Science and Biotechnology
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• 제15권5호
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• pp.715-720
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• 2006

This study was performed to develop a predictive model for the growth kinetics of Listeria monocytogenes in tryptic soy broth (TSB) using a response surface model with a combination of potassium lactate (PL), temperature, and pH. The growth parameters, specific growth rate (SGR), and lag time (LT) were obtained by fitting the data into the Gompertz equation and showed high fitness with a correlation coefficient of $R^2{\geq}0.9192$. The polynomial model was identified as an appropriate secondary model for SGR and LT based on the coefficient of determination for the developed model ($R^2\;=\;0.97$ for SGR and $R^2\;=\;0.86$ for LT). The induced values that were calculated using the developed secondary model indicated that the growth kinetics of L. monocytogenes were dependent on storage temperature, pH, and PL. Finally, the predicted model was validated using statistical indicators, such as coefficient of determination, mean square error, bias factor, and accuracy factor. Validation of the model demonstrates that the overall prediction agreed well with the observed data. However, the model developed for SGR showed better predictive ability than the model developed for LT, which can be seen from its statistical validation indices, with the exception of the bias factor ($B_f$ was 0.6 for SGR and 0.97 for LT).

• Physical Therapy Rehabilitation Science
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• 제11권4호
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• pp.535-545
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• 2022

Objective: This study was conducted to identify predictive factors of physical activity in total hip arthroplasty patients, and to provide basic data for the developing physical activity promotion program for total hip arthroplasty patients. Design: Descriptive correlational research. Methods: Data were collected from August 2017 to May 2018. Surveys were distributed to 60 patients in a G university hospital located at J city, Gyeongsangnam-do. Data were analyzed by frequency, mean, standard deviation, t-test, ANOVA, Pearson's correlation coefficient, multiple regression analysis using SPSS 24 Win program. Results: The variables affecting the 4-week physical activity after discharge were age (β=.07), residence after discharge (β=-.22), cerebrovascular disease (β=-.13), mental and behavioural disease (β=-.11), taking antibiotic (β=-.26), walking ability (β=.41), nutritional status (β=.25), depression (β=.05). The eight variables accounted for 39.4% in the 4-week physical activity (F=4.49 p=.001). The variables affecting the 8-week physical activity after discharge were age (β=.06), waking ability (β=.34), nutritional status (β=.20), exercise self-efficacy (β=.05), depression (β=-.05). The six variables accounted for 28.0% in the 8-week physical activity (F=4.58, p<.001). Conclusions: The walking ability in discharge important to improve the physical activity, there is a need to develop an program to improve walking ability before discharge, in total hip arthroplasty. There is a need to develop a physical activity program to consistently participate in a community.

• 대한화학회지
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• 제44권1호
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• pp.68-73
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• 2000

본 연구에서는 고등학교 학생들의 화학문제 해결력과 인지적 변인(논리적 사고력, 기억 용량,학습 전략) 및 정의적 변인(자아 효능감, 능력에 대한 자아 개념, 학습 목적, 과학에 대한 태도) 사이의 관계를조사하였다. 수리 문제와 개념 문제 해결력에 대한 변인들의 예언력을 중다 회귀 분석으로 조사하였다. 연구 결과, 인지적 변인 중 논리적 사고력이 수리 문제의 해결력을 유의미하게 설명하였고, 개념 문제의 해결력은 학습 전략이 가장 많이 설명하였으나 유의미하지는 않았다. 정의적 변인 중 능력에 대한 자아 개념은 수리 문제와 개념 문제 해결력 모두에 대해 유의미한 예언 변인이었으며, 자아 효능감은 개념 문제 해결력과 유의미한 상관이 있었으나 설명력은 없었다.

• 사물인터넷융복합논문지
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• 제5권2호
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• pp.55-66
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• 2019

본 연구는 간호대학생의 임상수행능력에 영향을 미치는 융합적인 요인들을 파악하기 위하여 실시하였다. 연구대상은 4년제 일 간호대학에 재학중인 간호대학생 185명이였으며 측정 도구는 셀프리더쉽, 비판적 사고성향, 자기주도학습능력, 문제해결과정, 임상수행능력에 관한 문항으로 구성되었다. 셀프리더쉽, 비판적 사고성향, 자기주도학습능력, 문제해결과정, 임상수행능력정도는 기술통계로 분석하였고 제 변수들 간의 상관관계는 Pearson correlation coefficients, 임상수행능력에 영향을 미치는 요인은 다중 선형 회귀분석(Multiple linear regression)을 적용하였다. 임상수행능력은 셀프리더쉽, 비판적 사고성향, 자기주도학습능력, 문제해결과정과 유의한 정적상관성이 있는 것으로 나타났다(r=.580, r=.604, r=.668, r=.627). 대인관계(β=.148), 비판적 사고성향(β=.158), 문제해결과정(β=.165), 자기주도학습능력(β=.321)순으로 유의미한 영향을 주는 것으로 나타나 임상수행능력의 53%를 설명하였다. 본 연구 결과를 토대로 간호대학생들의 임상수행능력을 향상시키기 위한 프로그램 개발에 활용할 수 있을 것이다.