• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2000년도 춘계학술발표논문집
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• pp.39-46
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• 2000

In pulp and papermaking process, enzymatic treatment of pulp fibres has been a topic of increasing interest in last decade. Lots of patents, papers and research reports were published on the application of enzymes in the fields of enzymatic bleaching, deinking, slime control, pitch control, waste water treatment and fibre modification. Cellulase and hemicellulase are the principal enzymes used for the modification of fibre property. This study was carried out for determinating the behaviors of enzyme to pulp fibres. A commercial enzyme, Denimax BT which is consisted with cellulase and hemicellulase, was treated to the kraft pulp produced from domestic hardwood mixtures. Results were mainly concentrated on the behaviors of freeness, drainability and fines content of fibres, and physical properties of paper with enzyme treatment. The freeness levels and dewatering ability were developed, and the fines contents were decreased. The creation of fines were controlled by the method of pre-enzyme treatment prior to fibre beating. The mechanical strength of paper, like tensile, burst, tear strength and folding endurance, were remarkably improved by the pre-enzyme treatment.

• 한국물환경학회지
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• 제25권5호
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• pp.720-726
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• 2009

We investigated the most effective pre-treatment processes and LC/MS/MS condition for microcystins analysis. With a step-by-step pre-treatment, efficiencies of several established methods were compared. At the level of cell burst, sonication method was found to be the most efficient. As a mycrocystins first extraction solvent, 5% acetic acid showed the highest efficiency. An isolation and recovery rate of mycrocystins of ODS Sep-Pak $C_{18}$ cartridge was higher than HLB SPE cartridge. As a final elution solvent from cartridge, 100% MeOH had a better efficiency than others. Using a LC/MS/MS, effective analytical methods were established. C18 reverse column was used and gradient elution was performed with using acetonitrile, 0.1% formic acid as a mobile phase. We analysed to 0.8 mL/min flow rate fit to the $5{\mu}m$ particle size column and $55^{\circ}C$ housing temperature. The validity of established analytical method was evaluated that MDL as average $0.050{\pm}0.014{\mu}g/L$ and LOQ as average $0.160{\pm}0.045{\mu}g/L$ had a good sensitivity over 40 magnification rather than $2{\mu}g/L$ detection limit of HPLC.

• 복식
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• 제36권
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• pp.109-119
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• 1998

For the purpose of standardization and practicability of natural dyeing, the mordanting and dyeing properties of Caseaslpinia Sappan, L. and Brazilin were studied. Appropriate extraction, dyeing and mordanting condition of Caeaslpinia Sappan, L. were determined, and the effect of mordanting method on dye up-take adn color fastness of dyed fabric was investigated. The most absorbance of Caeaslpinia Sappan, L. solution was 445nm, Brazilin was 448nm. The color of bazilin solution was affected by pH 7~9. The optimum temperature to extract Caesalpinia Sappan, L. was 10$0^{\circ}C$ adn dyeing solution for 1 hour. In case mordants concentration, the most absorbance was 0.3%. In case mordanting test, the best and proper temperature to quantities of absorbed mordants in silk was 8$0^{\circ}C$ and the most quantities of absorbed mordants in silk was mordant treatment by Cu. Effective dyeing time to silk was 60min. Effective mordanting temperature was 8$0^{\circ}C$, and its time was 30min. K/S value of dyeing fabrics was recoginazed by mordanting treat-ment, specially Fe, Sn, Al, Cu. K/S value of pre-mordanting was higher than post-mordanting. After soaping treatment K/S value of pre- and post-mordanting silk was decreased and 0.1%(W/V) quantity of mordant was sufficient for treatment. In the case of Caeaslpinia Sappan, L. fastness was increased by mordanting treatment. Mordants and mordanting treatment method affected the amount of absorption and color change of dyed silk.

• Communications for Statistical Applications and Methods
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• 제25권4호
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• pp.341-354
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• 2018

The one of the principles described in ICH E9 is that only results obtained from pre-specified statistical methods in a protocol are regarded as confirmatory evidence. However, in multi-regional clinical trials, even when results obtained from pre-specified statistical methods in protocol are significant, it does not guarantee that the test treatment is approved by regional regulatory agencies. In other words, there is no so-called global approval, and each regional regulatory agency makes its own decision in the face of the same set of data from a multi-regional clinical trial. Under this situation, there are two natural methods a regional regulatory agency can use to estimate the treatment effect in a particular region. The first method is to use the overall treatment estimate, which is to extrapolate the overall result to the region of interest. The second method is to use regional treatment estimate. If the treatment effect is completely identical across all regions, it is obvious that the overall treatment estimator is more efficient than the regional treatment estimator. However, it is not possible to confirm statistically that the treatment effect is completely identical in all regions. Furthermore, some magnitude of regional differences within the range of clinical relevance may naturally exist for various reasons due to, for instance, intrinsic and extrinsic factors. Nevertheless, if the magnitude of regional differences is relatively small, a conventional method to estimate the treatment effect in the region of interest is to extrapolate the overall result to that region. The purpose of this paper is to investigate the effects produced by this type of extrapolation via estimations, followed by hypothesis testing of the treatment effect in the region of interest. This paper is written from the viewpoint of regional regulatory agencies.

• 한국조리학회지
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• 제24권1호
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• pp.105-113
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• 2018

In this study, optimized pre-treatment conditions were investigated to improve the quality of gochujang apple jangachi. The moisture content was decreased by 14% in 60% sugar solution and 17% in 30% salt solution during 12 hours. On the one hand, in the case of dry sugar and salt method, moisture content was decreased rapidly by 20% and 24%, respectively during 12 hours. Compared with the sugar and salt solution method, the dry sugar and salt method was more effective in reducing moisture content during 12 hours. In the case of osmotic dehydration of the apple parts in the dry sugar method, the moisture content of the flesh, flesh including peel, and peel of apple decreased by 23%, 20%, and 16%, respectively during 6 hours. However, in the dry salt method, the moisture content of the flesh, flesh including peel, and peel of apple decreased by 19%, 12% and 13%, respectively during 2 hours. During this time, the pH tended to decrease, regardless of the presence of sugar and salt. Total acidity was slightly increased in the case of salt. In hot air drying after osmotic dehydration, the moisture content of flesh including peel of apple decreased from 64% and 67% to 31% and 27%, respectively at 90 minutes, and from 64% and 67% to 11% and 18% at 150 minutes, respectively. The moisture content of the peel decreased from 51% to 10% at 120 minutes. As a result of the sensory evaluation, the overall acceptance of the flesh and flesh including peel was highly evaluated, resultantly, the products were considered to be suitable for the production of gochujang apple jangachi.

• 한국작물학회지
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• 제26권2호
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• pp.179-184
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• 1981

본 시험은 1980년도에 전남대학교 시험포장에서 수행된 것으로서, Metribuzin의 처리시기에 따른 품종반응차이를 알기 위하여 광교외의 5대두품종과 Pre-sowing 외에 4처리 시기를 공시하여 작물의 초기생육반응을 조사하여 다음의 결과를 얻었다. 1. 공시품종내에서는 약제에 대한 저항성 차이가 뚜렷하지 않았다. 2. 품종차이보다는 약제처리시기에 따른 반응차이가 헌저하였으며, 대부분 대두품종의 저항성 크기는 E. Post-emg.< L.Post-emg $\ll$re-sowing=Control의 순으로 컸다. 3. Metribuzin의 약해 Symptom은 주당엽수 < 초장 $\ll$주당분지수의 순으로 뚜렷한 감소를 보이는 특징이었다. 4. 우리나라 대두품종에 대한 Metribuzin의 사용은 Pre-sowing이나 Pre-emg.가 추천되며, 특히 Pre-sowing에 대한 토양혼화법 연구와 단제보다는 혼용처리의 이점을 찾을 필요가 있다.

• 한국축산시설환경학회지
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• 제10권2호
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• pp.81-86
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• 2004

본 연구는 유지관리비가 적게 소요되고 관리가 용이한 에너지절감형 축산뇨오수 처리기술을 개발하기 위하여 목편 살수여상과 활성오니를 정화기술하는 처리기술을 연구하였다. 1. 스크레파 축사의 축산뇨오수 처리를 위한 목편칩 살수여상 활성오니 연계 시스템을 개발하였다. 처리공정은 축산뇨오수 원수$\to$스크린$\to$목편칩 살수여상$\to$활성오니$\to$침전/오존처리 공정으로 처리하였다. 2. 처리결과 축산뇨오수 원수의 BOD 8,620mg/$\iota$ 에서 최종처리수의 BOD는 58mg/$\iota$로 처리되었다. 또한 COD_{Mn},은 원수 4,290mg/$\iota$에서 232mg/$\iota$, SS 2,228mg/$\iota$에서 49.5mg/$\iota$, T-N 4,223mg/$\iota$에서 395mg/$\iota$, T-P 97.4mg/$\iota$에서 8.0mg/$\iota$로 처리되었다. 3. SS는 목편살수여상조에서 $71.1\%$가 제거되어 활성오니 처리 대비 슬러지 발생량이 $70\%$ 절감되었다.

• 대한후두음성언어의학회지
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• 제11권1호
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• pp.39-45
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• 2000

Background and Objectives : Accent method is one of holistic approaches for behavior readjustment of voice therapy The aim of this study is to evaluate the efficacy of the accent method of voice therapy for the patients who have no improvement after LMS. Materials and Methods : Of the patients who had been undergone LMS during the period from Jan. 1999 to Dec. 1999, medical records of 38 patients who had not been improved were studied retrospectively. 19 patients(treatment group) were applied accent method and the other 19 patients(control group) refused voice therapy. The voice of all the patients of both group were analysed with CSL and Aerophone II programs in pre- and post operative period. The voice of treatment group were analysed with Visi-Pitch II program before the application of accent method and after the completion of accent method. Then, the results were compared using paired t-test. Results : The results of voice analysis were not different statistically between pre- and postoperative examination in both group. After application of accent method in the treatment group, fundamental frequency(F$_{0}$) of male, relative average pertubation, and shimmer were revealed significant differences(p＜0.01), and decrease in grade(G) scale and roughness(R) scale were statistically Important in perceptual analysis using GRBAS criteria(p＜0.01). But $F_0$ of female, maximal phonation time and S to Z ratio were not revealed significant differences. Conclusions : Accent method of voice therapy may be as a supplement- ary therapy in the patients who were not improved after surgery.

• 대한정형도수물리치료학회지
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• 제16권2호
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• pp.48-52
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• 2010

Object: The aim of this study is to descrive the effect of neurodynamic technique and self management exercise for carpal tunnel syndrome patients(CTS) Method: 13 patients with CTS participated in this study. They were from 18 to 70 years old and mean age was 25.3. In the evalutaion, gripping with grip dynamometer, strength of gripping with precision pinchmeter, pain level with visual analogue scale. All measurement of each subject were measure at pre- treatment and post treatment(after 1week) and post treattment(after 2 weeks) stage. The physical therapy program consisted of neurodynamic technique and self management exercise. SPSS 12.0 program was used to compile result. Result: The grip, pinch, VAS-P were significantly difference between pre-treatment and post treatment(after 2weeks)(p<.05) Conclusion: This study suggest that 3weeks neurodynamic technique and self management exercise improved grip and pinch strength and decrease pain score.

• 대한기계학회논문집A
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• 제30권3호
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• pp.349-355
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• 2006

The gas turbine components is used on high temperature conditions which under severely circumstance with start-up and stop several times. Therefore, it is used nickel-base superalloys like and GTD-111DS. Damaged buckets on the t긴ade tip during operating are repaired per 24,000 hr to three times according to repair specification of manufacture. It is applied pre-heat, HIP(hot isostatic pressing) and post-heat treatment to support welding repair on blade tip effectively. On this study, It is utilize of $WRAP^{TM}$ (welding repair advanced process) method to make tension test specimens for this study, And then, material strength and characteristic for GTD-111DS was analyzed.