• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2000.04a
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• pp.39-46
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• 2000

In pulp and papermaking process, enzymatic treatment of pulp fibres has been a topic of increasing interest in last decade. Lots of patents, papers and research reports were published on the application of enzymes in the fields of enzymatic bleaching, deinking, slime control, pitch control, waste water treatment and fibre modification. Cellulase and hemicellulase are the principal enzymes used for the modification of fibre property. This study was carried out for determinating the behaviors of enzyme to pulp fibres. A commercial enzyme, Denimax BT which is consisted with cellulase and hemicellulase, was treated to the kraft pulp produced from domestic hardwood mixtures. Results were mainly concentrated on the behaviors of freeness, drainability and fines content of fibres, and physical properties of paper with enzyme treatment. The freeness levels and dewatering ability were developed, and the fines contents were decreased. The creation of fines were controlled by the method of pre-enzyme treatment prior to fibre beating. The mechanical strength of paper, like tensile, burst, tear strength and folding endurance, were remarkably improved by the pre-enzyme treatment.

• Journal of Korean Society on Water Environment
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• v.25 no.5
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• pp.720-726
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• 2009

We investigated the most effective pre-treatment processes and LC/MS/MS condition for microcystins analysis. With a step-by-step pre-treatment, efficiencies of several established methods were compared. At the level of cell burst, sonication method was found to be the most efficient. As a mycrocystins first extraction solvent, 5% acetic acid showed the highest efficiency. An isolation and recovery rate of mycrocystins of ODS Sep-Pak $C_{18}$ cartridge was higher than HLB SPE cartridge. As a final elution solvent from cartridge, 100% MeOH had a better efficiency than others. Using a LC/MS/MS, effective analytical methods were established. C18 reverse column was used and gradient elution was performed with using acetonitrile, 0.1% formic acid as a mobile phase. We analysed to 0.8 mL/min flow rate fit to the $5{\mu}m$ particle size column and $55^{\circ}C$ housing temperature. The validity of established analytical method was evaluated that MDL as average $0.050{\pm}0.014{\mu}g/L$ and LOQ as average $0.160{\pm}0.045{\mu}g/L$ had a good sensitivity over 40 magnification rather than $2{\mu}g/L$ detection limit of HPLC.

• Journal of the Korean Society of Costume
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• v.36
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• pp.109-119
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• 1998

For the purpose of standardization and practicability of natural dyeing, the mordanting and dyeing properties of Caseaslpinia Sappan, L. and Brazilin were studied. Appropriate extraction, dyeing and mordanting condition of Caeaslpinia Sappan, L. were determined, and the effect of mordanting method on dye up-take adn color fastness of dyed fabric was investigated. The most absorbance of Caeaslpinia Sappan, L. solution was 445nm, Brazilin was 448nm. The color of bazilin solution was affected by pH 7~9. The optimum temperature to extract Caesalpinia Sappan, L. was 10$0^{\circ}C$ adn dyeing solution for 1 hour. In case mordants concentration, the most absorbance was 0.3%. In case mordanting test, the best and proper temperature to quantities of absorbed mordants in silk was 8$0^{\circ}C$ and the most quantities of absorbed mordants in silk was mordant treatment by Cu. Effective dyeing time to silk was 60min. Effective mordanting temperature was 8$0^{\circ}C$, and its time was 30min. K/S value of dyeing fabrics was recoginazed by mordanting treat-ment, specially Fe, Sn, Al, Cu. K/S value of pre-mordanting was higher than post-mordanting. After soaping treatment K/S value of pre- and post-mordanting silk was decreased and 0.1%(W/V) quantity of mordant was sufficient for treatment. In the case of Caeaslpinia Sappan, L. fastness was increased by mordanting treatment. Mordants and mordanting treatment method affected the amount of absorption and color change of dyed silk.

• Communications for Statistical Applications and Methods
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• v.25 no.4
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• pp.341-354
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• 2018

The one of the principles described in ICH E9 is that only results obtained from pre-specified statistical methods in a protocol are regarded as confirmatory evidence. However, in multi-regional clinical trials, even when results obtained from pre-specified statistical methods in protocol are significant, it does not guarantee that the test treatment is approved by regional regulatory agencies. In other words, there is no so-called global approval, and each regional regulatory agency makes its own decision in the face of the same set of data from a multi-regional clinical trial. Under this situation, there are two natural methods a regional regulatory agency can use to estimate the treatment effect in a particular region. The first method is to use the overall treatment estimate, which is to extrapolate the overall result to the region of interest. The second method is to use regional treatment estimate. If the treatment effect is completely identical across all regions, it is obvious that the overall treatment estimator is more efficient than the regional treatment estimator. However, it is not possible to confirm statistically that the treatment effect is completely identical in all regions. Furthermore, some magnitude of regional differences within the range of clinical relevance may naturally exist for various reasons due to, for instance, intrinsic and extrinsic factors. Nevertheless, if the magnitude of regional differences is relatively small, a conventional method to estimate the treatment effect in the region of interest is to extrapolate the overall result to that region. The purpose of this paper is to investigate the effects produced by this type of extrapolation via estimations, followed by hypothesis testing of the treatment effect in the region of interest. This paper is written from the viewpoint of regional regulatory agencies.

• Culinary science and hospitality research
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• v.24 no.1
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• pp.105-113
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• 2018

In this study, optimized pre-treatment conditions were investigated to improve the quality of gochujang apple jangachi. The moisture content was decreased by 14% in 60% sugar solution and 17% in 30% salt solution during 12 hours. On the one hand, in the case of dry sugar and salt method, moisture content was decreased rapidly by 20% and 24%, respectively during 12 hours. Compared with the sugar and salt solution method, the dry sugar and salt method was more effective in reducing moisture content during 12 hours. In the case of osmotic dehydration of the apple parts in the dry sugar method, the moisture content of the flesh, flesh including peel, and peel of apple decreased by 23%, 20%, and 16%, respectively during 6 hours. However, in the dry salt method, the moisture content of the flesh, flesh including peel, and peel of apple decreased by 19%, 12% and 13%, respectively during 2 hours. During this time, the pH tended to decrease, regardless of the presence of sugar and salt. Total acidity was slightly increased in the case of salt. In hot air drying after osmotic dehydration, the moisture content of flesh including peel of apple decreased from 64% and 67% to 31% and 27%, respectively at 90 minutes, and from 64% and 67% to 11% and 18% at 150 minutes, respectively. The moisture content of the peel decreased from 51% to 10% at 120 minutes. As a result of the sensory evaluation, the overall acceptance of the flesh and flesh including peel was highly evaluated, resultantly, the products were considered to be suitable for the production of gochujang apple jangachi.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.26 no.2
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• pp.179-184
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• 1981

The study was conducted to know the differential growth responses of soybean cultivars as affected by various application stages of Metribuzin herbicide, at the University experimental farm of Chonnam Nat'l. Univ, Kwangjoo, 1980. Experimented soybean materials were six cultivars, as Kwanggyo, Dongbuktae, Bongui, Yukwoo 3, Suweon 85, and Suweon 86., . and Laid-out application stages were five as pre-sowing, Pre-emergence, Early Post-emergence, and Late Post-emergence treatment comparing with Control. Results obtained from the study were as follows: Among experimented soybean cultivars, no significantly tolerant cultivar was shown. Highly significant differences in phytotoxicities by Metribuzin treatments were detected among various application stages, and crop tolerances were recognized bigger in order as E. Post-emg. < L. Post-emg. $\ll$ Pre-emg. < Pre-sowing $\leq$ Control. The phytotoxic symptoms of all soybean cuitivars were severely recorded in order of Leaf No. /Plant < Plant height $\ll$ Branch No. /Plant. For the cultivation of most soybean cuitivars, the use of Metribuzin in Pre-sowing or Pre-emergence were recommended, and especially it is expected to follow of more detailed study on soil-incorporation method in Pre-sowing treatment, and rather the tank-mixture system of Metribuzin with others than the mono-application system for the safe-use and enlargement of weeding-spectrum.

• Journal of Animal Environmental Science
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• v.10 no.2
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• pp.81-86
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• 2004

This experiment was conducted to evaluate combination system of wood chip trickling system and activated sludge process. The results obtained are summarized as tallows. The trickling filter system using wood chip was used as a biological pre-treatment system for treating piggery wastewater. At pre-treatment the removal efficiencies were BOD $91\%$ CODmn $65\%$, SS $75\%$ T-N $73\%$, T-P $69\%$. After pre-treatment the removal efficiencies in activated sludge process were BOD $99\%$ CODmn $94.6\%$, SS $97.8\%$ T-N $91.1\%$, T-P $91\%$. This study shows a very stable method with pre-treatment of trickling filter using wood chip. These combined treatment system was very useful for piggery wastewater.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.11 no.1
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• pp.39-45
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• 2000

Background and Objectives : Accent method is one of holistic approaches for behavior readjustment of voice therapy The aim of this study is to evaluate the efficacy of the accent method of voice therapy for the patients who have no improvement after LMS. Materials and Methods : Of the patients who had been undergone LMS during the period from Jan. 1999 to Dec. 1999, medical records of 38 patients who had not been improved were studied retrospectively. 19 patients(treatment group) were applied accent method and the other 19 patients(control group) refused voice therapy. The voice of all the patients of both group were analysed with CSL and Aerophone II programs in pre- and post operative period. The voice of treatment group were analysed with Visi-Pitch II program before the application of accent method and after the completion of accent method. Then, the results were compared using paired t-test. Results : The results of voice analysis were not different statistically between pre- and postoperative examination in both group. After application of accent method in the treatment group, fundamental frequency(F$_{0}$) of male, relative average pertubation, and shimmer were revealed significant differences(p＜0.01), and decrease in grade(G) scale and roughness(R) scale were statistically Important in perceptual analysis using GRBAS criteria(p＜0.01). But $F_0$ of female, maximal phonation time and S to Z ratio were not revealed significant differences. Conclusions : Accent method of voice therapy may be as a supplement- ary therapy in the patients who were not improved after surgery.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.2
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• pp.48-52
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• 2010

Object: The aim of this study is to descrive the effect of neurodynamic technique and self management exercise for carpal tunnel syndrome patients(CTS) Method: 13 patients with CTS participated in this study. They were from 18 to 70 years old and mean age was 25.3. In the evalutaion, gripping with grip dynamometer, strength of gripping with precision pinchmeter, pain level with visual analogue scale. All measurement of each subject were measure at pre- treatment and post treatment(after 1week) and post treattment(after 2 weeks) stage. The physical therapy program consisted of neurodynamic technique and self management exercise. SPSS 12.0 program was used to compile result. Result: The grip, pinch, VAS-P were significantly difference between pre-treatment and post treatment(after 2weeks)(p<.05) Conclusion: This study suggest that 3weeks neurodynamic technique and self management exercise improved grip and pinch strength and decrease pain score.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.3 s.246
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• pp.349-355
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• 2006

The gas turbine components is used on high temperature conditions which under severely circumstance with start-up and stop several times. Therefore, it is used nickel-base superalloys like and GTD-111DS. Damaged buckets on the t긴ade tip during operating are repaired per 24,000 hr to three times according to repair specification of manufacture. It is applied pre-heat, HIP(hot isostatic pressing) and post-heat treatment to support welding repair on blade tip effectively. On this study, It is utilize of $WRAP^{TM}$ (welding repair advanced process) method to make tension test specimens for this study, And then, material strength and characteristic for GTD-111DS was analyzed.