• Journal of Ginseng Research
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• 제35권1호
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• pp.45-51
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• 2011

Wild ginseng has been used as a traditional medicine for thousands of years and for increase physical strength in Korea, China and Japan. This study reports that cultivated wild ginseng (CWG) inhibits adipocyte differentiation of 3T3-L1 pre-adipocytes in a concentration-dependent manner. Inhibition of adipocyte differentiation is one possible anti-obesity strategy. CWG inhibits the expression of the adipocyte differentiation regulator peroxisome proliferators-activated receptor (PPAR)${\gamma}$ and CCAAT/enhancer-binding protein ${\alpha}$mRNA. It also inhibited the expression of PPAR${\gamma}$ and adiponectin at the protein level during the differentiation of pre-adipocytes into adipocytes. Additionally, CWG blocked the cell cycle at the sub-$G_1$ phase transition, causing cells to remain in the pre-adipocyte state. These results indicate that CWG inhibits adipocyte differentiation and adipogenesis through pre-adipocyte cell cycle arrest in cultured 3T3-L1 cells.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.538-541
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• 2009

Increasing of number of people who suffered from long term chronic diseases which required frequent daily health monitoring and body check up in conjunction with the trendy uses of mobile phones and Personal Digital Assistants (PDAs) in various ubiquitous computing had make portable healthcare system a well known application today. A mobile phone based portable healthcare monitoring system with multiple vital signals monitoring ability at real time in WSN and CDMA network is developed. This system carries out real time monitoring and local data analysis process in the mobile phone. Any detection of abnormal health condition and diagnosis at earlier stage will reduce the risk of patient's life. As an extension to the existing model, a pre-diagnosis management system (PDMS) is designed to minimize the time consuming in pre-diagnosis process in the hospital or healthcare center. An alert is sent to the web server at the healthcare center when the patient detects his health is at critical state where the immediate diagnosis is needed. Preparation of diagnosis equipments and arrangement of doctor and nurses at the hospital side can be done earlier before the arrival of patient at the hospital with the help of PDMS. An efficient pre-diagnosis management increases the chances of diseases recovery rate as well.

• 대한치과교정학회지
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• 제25권3호
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• pp.355-373
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• 1995

두개악안면 영역은 많은 해부학적 구조를 포함하는 근골격구조(musculodentos keletal system)로 두부골격의 구조, 악궁상태, 저작근의 형성 및 기능은 서로 밀접한 연관성을 가지고 있다. 두개악안면 영역의 성장과 발육은 유전적인 요인이외에 환경적인 요인들 즉, 두개안면부의 근육을 포함한 주위조직의 영향을 받는 것으로 이미 알려져 있다. 그러나 반대로 두개안면부의 골격구조가 변화되는 경우 이에 대응하여 두개안면근육의 기능 또한 변화, 적응되는지에 대해서는 체계적인 연구결과가 미흡한 상태이다. 저자는 골격형 제 III급 부정교합자의 악교정수술 전, 후의 근활성도의 변화에 대한 비교연구를 통해 두부 골격구조와 교합상태에 따른 저작근 기능의 상호관계 및 변화 양상에 대해 알아보고자 정상교합을 가진 성인남자 15명과 술전 및 술후 골격형 제 III급 부정교합자 각각 15명을 대상으로 측모두부 방사선사진과 저작효율검사 및 rest, clenching, chewing, swallowing시의 전측두근, 교근, 상순의 근활성도 검사를 시행하여 다음과 같은 결과를 얻었다. 1. 하악의 안정위(rest)에서 술전 부정교합군에서 술후군보다 전측두근, 교근, 상순에서 높은 활성도를 보였으며, 술후군에서는 상순에서만 정상대조군보다 의미있는 높은 근활성도를 보였다. 2. 최대교합(clenching)시는 술후군에서 술전 부정교합군보다 전측두근, 교근, 상순에서 높은 근활성도를 보였다. 3. 저작(chewing)시는 술후군이 술전 부정교합군보다 전측두근 및 교근에서 높은 활성을 보인 반면 상순에서는 감소된 근활성도를 보였다. 4. 연하(swallowing)시 술후군에서 상순은 술전 부정교합군보다 감소되었으나 정상대조군보다 증가된 근활성도를 나타냈으며, 각 군간에 전측두근 및 교근에서는 유의차가 없었다. 5. 저작효율은 술전부정교합군에서 정상대조군보다 낮았으며, 술후군에서 술전 부정교합군보다 증가되었으나 두군 모두 정상대조군과 유의차를 보였다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.261-261
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• 2000

This paper analyzes the characteristics of pre-sliding friction of an X-Y table of CNC machining center at velocity reversal, and presents a simple and effective method of friction compensation based on this characteristics. At velocity reversal, a large position tracking error occurs because of the discontinuous change of friction. The relationship between the occurrence time of maximum position tracking error and the acceleration at zero velocity is analyzed by using the spring-like friction model. Furthermore, the experimental observation verifies this relation. From this, the state transition tine from pre-sliding regime into sliding regime can be predicted. Using the predicted transition time, the friction can be effectively compensated and table experimental results show its effectiveness.

• Macromolecular Research
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• 제11권4호
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• pp.241-249
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• 2003

A molecular-thermodynamic model to describe the salt-induced protein precipitation is developed based on the perturbation theory. We employed the modified perturbed hard-sphere-chain (PHSC) equation of state for copolymer mixtures to take into account the pre-aggregation effect among protein particles. Hypothetical pressure-composition diagrams are computed with various size differences and salt concentrations. The precipitation behaviors are also studied for various types of pre-aggregation effect for the given systems.

• Bulletin of the Korean Chemical Society
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• 제16권10호
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• pp.972-976
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• 1995

A trace amount of 4-biphenylcarboxylate having a pre-twisted biphenyl moiety was attached to a poly(methyl methacrylate) side chain and the fluorescence properties of the chromophore were investigated in various solvents such as ethyl acetate and butyl chloride. At room temperature, the polymer exhibited a distinct red shift of the short wavelength emission (325 nm) and an enhanced emission intensity around 430 nm upon excitation at the absorption red edge. The temperature dependence of the intensity ratio (R) of the 325 nm emission to the 430 nm emission was observed when exciting at the red edge over the temperature range between -20 and 60 ℃. However, the temperature dependence was not observed when exciting at the shorter wavelength. The Arrhenius plot of the R value shows the activation energy of 6.0 kJ/mol which is in good agreement with the energy required for the twist of the biphenyl moiety. Together with the results of red edge excitation effects it was concluded that the pre-twisted geometry of the biphenyl moiety is preserved by the restriction of the polymer chain to facilitate the formation of the twisted intramolecular charge transfer (TICT) state upon excitation.

• 센서학회지
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• 제30권5호
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• pp.290-294
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• 2021

Experts have designed popular and successful model architectures, which, however, were not the optimal option for different scenarios. Despite the remarkable performances achieved by deep neural networks, manually designed networks for classification tasks are the backbone of object detection. One major challenge is the ImageNet pre-training of the search space representation; moreover, the searched network incurs huge computational cost. Therefore, to overcome the obstacle of the pre-training process, we introduce a network adaptation technique using a pre-trained backbone model tested on ImageNet. The adaptation method can efficiently adapt the manually designed network on ImageNet to the new object-detection task. Neural architecture search (NAS) is adopted to adapt the architecture of the network. The adaptation is conducted on the MobileNetV2 network. The proposed NAS is tested using SSDLite detector. The results demonstrate increased performance compared to existing network architecture in terms of search cost, total number of adder arithmetics (Madds), and mean Average Precision(mAP). The total computational cost of the proposed NAS is much less than that of the State Of The Art (SOTA) NAS method.

• Journal of Mechanical Science and Technology
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• 제17권1호
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• pp.105-113
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• 2003

This paper proposes a systematic design methodology for the Takagi-Sugeno (TS) model based fuzzy state feedback control system with multi-objectives. In this investigation, the objectives are set to be guaranteed stability and pre-specified transient performance, and this scheme is applied to a nonlinear magnetic bearing system. More significantly, in the proposed methodology, the control design problems that consider both stability and desired transient performance are reduced to the standard LMI problems. Therefore, solving these LMI constraints directly (not trial and error) lead to a fuzzy state-feedback controller such that the resulting fuzzy control system meets the above two objectives. Simulation and experimentation results show that the Proposed LMI-based design methodology yields not only maximized stability boundary but also the desired transient responses.

• 산업기술연구
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• 제15권
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• pp.203-208
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• 1995

This paper suggests the three dimensional steady state searching techniques of hard disk/head system, which has some skew angle with flexure. In order to analyze the steady state behaviors of magnetic head slider, the localized Knudsen number and the localized bearing numbers are sued. For finding the steady state of magnetic head slider under the pre-loaded condition, I proposed multi-dimensional Newton-Raphson method which traces the equilibrium position of magnetic head slider, which has 3-degrees of freedom, using Jacobian matrix. The multi-dimensional Newton-Raphson method is very efficient technique for finding the steady state position of magnetic head slider because it approaches to the equilibrium position with changing three parameters simultaneously.

• 수완나부미
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• 제3권1호
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• pp.1-23
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• 2011

This paper traces the process how Confucianism was established as a state ideology in Vietnam. Confucianism is said to have first been introduced into Vietnam around the early 3rd century. However, it had been outshone by Buddhism until the 1389s when Ho Quy Ly rose to power and emphasized pre-Qin Confucianism. In 1428, Lê Loi founded a new dynasty and changed the state ideology from Buddhism to Confucianism. Despite this radical shift, however, Confucianism was not firmly established at the beginning of the Lê Dynasty. It was Lê Thanh Tong (1460-1497) who fully established neo-Confucianism as the state ideology. The reason was that he devoted himself to the study of Confucian texts from a young age and sought to strengthen his own royal authority by emphasizing the neo-Confucian concept of loyalty and filial piety.