• Title/Summary/Keyword: pre-exposure

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Seasonal variations of volatile organic compounds (VOCs) in indoor air of daycare centers (보육시설 실내공기 중 휘발성유기화합물(VOCs)의 계절적 농도변화에 대한 연구)

  • Jang, Seong-Ki;Chun, Jae-Young;Kim, Sung-Youn;Park, Suk-Young;Ryu, Jung-Min;Lim, Jung-Yeon;Lee, Woo-Suk
    • Analytical Science and Technology
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    • v.20 no.6
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    • pp.474-482
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    • 2007
  • Daycare centers are an important indoor environment for pre-school children and exposure area with potential harmful health effects for infants and children who spend most of their daily life. Sampling was undertaken at 29 daycare centers located Seoul in Korea from January, 2006 to December 2006. The target compounds were 7 individual volatile organic compounds (benzene, toluene, ethylbenzene, m,p-xylene, styrene, o-xylene, TVOC). The mean concentrations of TVOC, toluene, m ,p-xylene, ethylbenzene, benzene and styrene in daycare centers were $318.7{\mu}g/m^3$, $51.6{\mu}g/m^3$, $11.7{\mu}g/m^3$, $6.5{\mu}g/m^3$, $4.2{\mu}g/m^3$, $3.6{\mu}g/m^3$, respectively. Toluene occupied 17.6 % of the concentration of individual VOCs. The ratio of indoor and outdoor (I/O) of TVOC and toluene were 2.0 and 1.6, respectively. The results of characteristics according to a season of a year, the concentration of TVOC were measured $433.9{\mu}g/m^3$, and these concentrations during third quarter of the year in summer were higher than the other season. In the other four seasons, TVOC were measured 280.5 in winter, 298.3 in spring and $264.6{\mu}g/m^3$ in fall, respectively.

Numerical Analysis of Collapse Behavior in Industrial Stack Explosive Demolition (산업용 연돌 발파해체에서 붕괴거동에 관한 수치해석적 연구)

  • Pu-Reun Jeon;Gyeong-Jo Min;Daisuke Fukuda;Hoon Park;Chul-Gi Suk;Tae-Hyeob Song;Kyong-Pil Jang;Sang-Ho Cho
    • Explosives and Blasting
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    • v.41 no.3
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    • pp.62-72
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    • 2023
  • The aging of plant structures due to industrialization in the 1970s has increased the demand for blast demolition. While blasting can reduce exposure to environmental pollution by shortening the demolition period, improper blasting design and construction plans pose significant safety risks. Thus, it is vital to consider optimal blasting demolition conditions and other factors through collapse behavior simulation. This study utilizes a 3-D combined finite-discrete element method (FDEM) code-based 3-D DFPA to simulate the collapse of a chimney structure in a thermal power plant in Seocheon, South Korea. The collapse behavior from the numerical simulation is compared to the actual structure collapse, and the numerical simulation result presents good agreement with the actual building demolition. Additionally, various numerical simulations have been conducted on the chimney models to analyze the impact of the duct size in the pre-weakening area. The no-duct, duct, and double-area duct models were compared in terms of crack pattern and history of Z-axis displacement. The findings show that the elapse-time for demolition decreases as the area of the duct increases, causing collapse to occur quickly by increasing the load-bearing area.

Comparative Analysis of Particulate Matter, Black Carbon, and Noise Levels Before and After Installation of a Safety Wall in a Pedestrian Walkway within an Urban Tunnel (도심터널 보행로 안전벽 설치 전후의 미세먼지, 블랙카본, 소음 수준 비교)

  • Myoungho Lee;Jongmin Park;Sohyun Kang;Jeongyeon Park;Taehong Kwon;Chungsik Yoon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.34 no.3
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    • pp.214-221
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    • 2024
  • Objectives: People using pedestrian walkways within tunnels may be exposed to environmental hazards that can have adverse effects on their health. This study aimed to measure changes in the levels of particulate matter (PM10), black carbon (BC), and noise after the installation of safety walls on pedestrian walkways within tunnels. Methods: Measurements were taken at the entrances on both sides of a tunnel and at the central point, both before and after the installation of pedestrian safety walls. Additionally, measurements were conducted by distinguishing between non-rush hour and rush hour periods to account for variations in the number of vehicles using the tunnel. A SidePak was used for PM10 measurements, an aethalometer for BC, and a sound level meter for noise. Results: PM10 showed the highest concentrations at the center of the tunnel at both pre- and post-installation of safety walls, as well as during rush hour periods. After the installation, the concentration at the center was 31.09 ± 14.02 ㎍/m3 (19.44 ± 8.02% increase). During rush hour, BC concentration reached 2.28 ± 1.55 ㎍/m3, indicating a 26.71 ± 13.19% increase compared to non-rush hour. As for noise, installation of safety walls reduced noise levels about 3 - 6 dB (8.10 ± 3.31% decrease). Conclusions: It was confirmed that installing safety walls on pedestrian walkways within the tunnel can reduce noise levels. However, the interior of a tunnel is a poorly ventilated environment, and exposure levels vary depending on the length of the tunnel. Therefore, the development of safety measures related to this issue is warranted, and further research on harmful substances within the tunnel should be conducted.

Differential Susceptibility to High Temperature and Variation of Seasonal Occurrence between Spodoptera exigua and Plutella xylostella (파밤나방과 배추좀나방의 고온 감수성 차이와 연중 발생 변이)

  • Kim, Minhyun;Lee, Seunghee;Kim, Yonggyun
    • Korean journal of applied entomology
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    • v.55 no.1
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    • pp.17-26
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    • 2016
  • Climate change has been regarded as one of main factors to change Korean insect pest fauna. Especially, a global warming model predicts to expand habitat for insect pests originated from tropical or subtropical regions. Two insect pests, the beet armyworm (Spodoptera exigua) and the diamondback moth (Plutella xylostella), are known to overwinter in some greenhouse conditions without diapause induction in Korea. There was a clear difference between these two insects in seasonal occurrence. P. xylostella occurred only at early spring and fall seasons, but did not occur during summer. In contrast, S. exigua maintained their occurrence from late spring to fall seasons. This study set up a hypothesis that the difference in the seasonal occurrence may be resulted from variation in susceptibility to high temperature. To test the hypothesis, heat tolerance was compared between these two insects. Exposure to $42^{\circ}C$ for 40 min killed 100% individuals of P. xylostella larvae. However, most larvae of S. exigua survived in response to $42^{\circ}C$ even for 80 min. Heat tolerance varied among developmental stages in both insects. Highest tolerant stages were $4^{th}$ instar larvae and adults for P. xylostella, but $1^{st}$ instar larvae for S. exigua. Pre-exposure to $37^{\circ}C$ for 30 min significantly increased heat tolerance in both insects. Induction of heat tolerance accompanied with significant increase of glycerol contents in the hemolymph in both insects and up-regulation of three heat shock protein expressions in S. exigua. These results suggest that the differential susceptibility to high temperature explains the disappearance of P. xylostella during summer, at which S. exigua maintains its occurrence.

The Comparison of Noise-induced Hearing Loss Evaluation Criteria for Management (소음성난청 관리를 위한 판정기준간의 비교)

  • 남궁원자;원정일
    • Journal of environmental and Sanitary engineering
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    • v.13 no.1
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    • pp.123-134
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    • 1998
  • The study was performed to investigate the differences among various evaluation criteria for noise-induced hearing loss(NIHL). The subjects were 100 workers who had received detailed audiometric examinations after the periodic annual examination for hearing loss. The evaluation criteria included were as follows: The criterion I was NIHL of 50dB or greater at 4,000Hz in either ear which is one of the legal requirements for determining occupational hearing loss in Korea. The criterion II was NIHL of 40dB or greater by 4-divided classification(a+b+c+d/4 at 500Hz(a), 1,000Hz(b), 2,000Hz(c), 4,000Hz(d)) which is also one of the legal requirements for determining occupational hearing loss in Korea. The criterion III was NIHL of 31dB of greater by 6-divided classification(a+2b+2c+d/6) which is the workers' compensation standard. The criterion IV was NIHL of 40dB or greater by 6-divided classification(a+2b+2c+d/6), the criterion used to prohibite workers to be employed in the noisy workplace. The criterion V was NIHL of 40dB or greater by 3-divided classification(a+b+c/3) which is the guideline of the Japanes Labour Department. The results were as follows; 1. The percentage of workers with NIHL by the criterion I was the highest(96%) and covered all workers with NIHL diagnosed by other criteria. Therefore, this criterion was the most sensitive one for early detection of NIHL among various evaluation criteria. 2. The percentage of workers with NIHL by the criterion II was 29% of the subjects, but all of them could be diagnosed as having NIHL by the criterion I and 33.1% of the NIHL by the criterion III could not be covered by the criterion II. Thus, this criterion was not considered suitable as an initial step for determining occupational hearing loss. 3. The percentage of workers with NIHL by the criterion III was 45% of the subjects. This percentage was 46.9% of the NIHL by the criterion I and was estimated to cover 3.6% of all noise exposed workers. 4. The percentage of workers with NIHL by the criterion IV was 28% of the subjects, but 37.8% of the NIHL by the criterion III and 70.8% of the NIHL by the criterion I were not covered by the criterion. Therefore, these workers could have been employed in the noisy workplaces. 5. Employed relocation which was one of the post management methods was an option in the criterion I in Korea and in the criterion V in Japan. The number of NIHL by the criterion I was 6.7times greater than that by the criterion V. Thus, although employee relocation was not used exclusively, many more workers with NIHL could have been relocated. In conclusion, this study revealed that the criteria being used for managing occupational hearing loss showed a lack uniformity among them. In addition, since these criteria are all relied on the total threshold shifts caused by the noise exposure at the time of hearing test with no consideration given to the past noise exposure history nor age, it can be said that they are not an effective tool for occupational hearing loss management. Since legal requirements are usually followed after being diagnosed as having NIHL, it is recommended that a uniform diagnostic criterion should be used to minimize confusion. Pre-employment hearing tests should also be utilized so as to managing occupational hearing loss after employment rather than being used as a legal roadblock of prohibiting workers with mild hearing loss from being employed. Thus, what is needed is an establishment of a rational criterion for occupational hearing loss management rather than for legal requirements.

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Packing effects on the intracavitary radiation therapy of the utaine lervix cancer ($^{192}Ir$source를 이용할 자궁경부암 강내치료시 사용하는 packing의 효과에 대한 고찰)

  • Cho, Jung-Kun;Lee, Du-Hyun;Si, Chang-Kun;Choi, Yoon-Kyung;Kim, Tae-Yoon
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.1
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    • pp.73-77
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    • 2004
  • Purpose of the radio-therapy is maximize the radiation dose to the tumor while minimizing the dose to the critical organ. Carcinoma of the uterine cervix treatment are external irradiation or an interstitial brachtheraphy make use of isotope. Brachytherapy is a method of radiotherapy in advantage to achieve better local control with minimum radiation toxicity in comparison with external irradiation because radiation dose is distributed according to the inverse square low of gamma-ray emitted from the implanted sources. Authors make use of the patients data which 192Ir gives medical treatment intrcavity. Intracavitary radiation of the uterine cervix cancer, critical organ take $20\%$ below than exposure dose of A point in the ICRU report. None the less of the advice, Radiation proctitis and radiation cystitis are frequent and problematic early complications in patients treated with radiation for the uterine cervix cancer. In brachytherapy of uterine cervical cancer using a high dose rate remote afterloading system, it is of prime importance to deliver a accurate dose in each fractionated treatment by minimizing the difference between the pre-treatment planned and post-treatment calculated doses. Use of packing to reduce late complications intracavitary radiation of the uterine cervix cancer. Bladder and rectum changes exposure dose rate by radiotherphy make use of packing.

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The Protective Role of Gleditsiae fructus against Streptococcus pneumoniae (폐렴 구균에 대한 조협의 보호 역할 연구)

  • Jun-ki Lee;Se-Hui Lee;Dong Ju Seo;Kang-Hee Lee;Sojung Park;Sun Park;Taekyung Kim;Jin-Young Yang
    • Journal of Life Science
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    • v.33 no.2
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    • pp.158-168
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    • 2023
  • Natural products have been used to mitigate the effects of cancer and infectious diseases, as they feature diverse bioactivities, such as antioxidant, antibacterial, anti-inflammatory, and immunomodulatory effects. Here, we chose 10 natural products that are well-known as pulmonary enhancers and investigated their bactericidal effects on Streptococcus pneumoniae. In the disk diffusion assay, the growth of S. pneumoniae was significantly regulated by G. fructus treatment regardless of extraction method used. We first adopted spraying as a novel delivery method for G. fructus. Interestingly, mice exposed to G. fructus three times a day for 2 weeks were resistant to S. pneumoniae intranasal infection (shown both through body weight loss and survival rates compared to the control group). Moreover, we confirmed that exposure to G. fructus regulated the colonization of the bacteria despite the sustained inflammation in the lung after exposure to S. pneumoniae, indicating that migrated inflammatory immune cells may involve a host defense mechanism against pulmonary infectious diseases. While a similar number of granulocytes (CD11b+Ly6C+Ly6G+), neutrophils (CD11b+Ly6CintLy6G+), and monocytes (CD11b+Ly6CintLy6G-) were found between groups, a significantly increased number of alveolar macrophages (CD11b+CD11chiF4/80+) was detected in BAL fluids of mice pre-exposed to G. fructus at 5 days after S. pneumonia infection. Taken together, our data suggest that this usage of G. fructus can induce protective immunity against bacterial infection, indicating that facial spray may be helpful in enhancing the defense mechanism against pulmonary inflammation and in evaluating the efficacy of natural products as immune enhancers against respiratory diseases.

Improvement of the Efficacy Test Methods for Hand Sanitizers (Gel, Liquid, and Wipes): Emerging Trends from in vivo/ex vivo Test Strategies for Application in the Hand Microbiome (손소독제(겔형, 액제형, 와이프형)의 효능 평가법 개선: 평가 전략 연구 사례 및 손 균총 정보 활용 등 최근 동향)

  • Yun O;Ji Seop Son;Han Sol Park;Young Hoon Lee;Jin Song Shin;Da som Park;Eun NamGung;Tae Jin Cho
    • Journal of Food Hygiene and Safety
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    • v.38 no.1
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    • pp.1-11
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    • 2023
  • Skin sanitizers are effective in killing or removing pathogenic microbial contaminants from the skin of food handlers, and the progressive growth of consumer interest in personal hygiene tends to drive product diversification. This review covers the advances in the application of efficacy tests for hand sanitizers to suggest future perspectives to establish an assessment system that is optimized to each product type (gel, liquid, and wipes). Previous research on the in vivo simulative test of actual consumer use has adopted diverse experimental conditions regardless of the product type. This highlights the importance of establishing optimal test protocols specialized for the compositional characteristics of sanitizers through the comparative analysis of test methods. Although the operational conditions of the mechanical actions associated with wiping can affect the efficacy of the removal and/or the inactivation of target microorganisms from the skin's surface, currently there is a lack of standardized use patterns for the exposure of hand sanitizing wipes to skin. Thus, major determinants affecting the results from each step of the overall assessment procedures [pre-treatment - exposure of sanitizers - microbial recovery] should be identified to modify current protocols and develop novel test methods. The ex vivo test, designed to overcome the limited reproducibility of in vivo human trials, is also expected to replicate the environment for the contact of sanitizers targeting skin microorganisms. Recent progress in the area of skin microbiome research revealed distinct microbial characteristics and distribution patterns after the application of sanitizers on hands to establish the test methods with the perspectives on the antimicrobial effects at the community level. The future perspectives presented in this study on the improvement of efficacy test methods for hand sanitizers can also contribute to public health and food safety through the commercialization of effective sanitizer products.

The Effects of Various Vegatable Pesticides on Materials of Cultural Property - Dyed and Undyed Silk Fabrics, Cotton Fabrics and Korean Papers, Undyed Ramie Fabric, Pigments, Painted Plates - (식물에서 추출한 살충.살균제가 문화재 재질에 미치는 영향 - 견직물, 면직물, 저마직물, 한지, 안료분말, 채색편 -)

  • Oh, Joon-Suk
    • Journal of Conservation Science
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    • v.20
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    • pp.9-22
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    • 2007
  • Three kinds of natural pesticides extracted from plants which are being sold in the Korean markets, were estimated effects on materials of art of museum. Tested samples were 1) silk fabrics : undyed, dyed(amur cork tree, gallut, gallut(alum post mordancy), gallut(copperas post mordancy), gardenia, turmeric, acorn, acorn(copperas post mordancy), gromwell, madder, madder(alum post mordancy), safflower, sappanwood, sappanwood(alum pre mordancy, post mordancy), indigo, indigo+amur cork tree, indigo+sappanwood) 2) cotton fabrics : undyed, dyed(amur cork tree, gallut, gallut(alum post mordancy), gardenia, acorn, acorn(copperas post mordancy), gromwell, madder, madder(alum post mordancy), safflower, sappanwood, sappanwood(alum pre mordancy, post mordancy), indigo, indigo+sappanwood) 3) undyed ramie fabric 4) Korean papers : undyed, dyed(sappanwood, indigo, gardenia, amur cork tree, safflower) 5) pigments : azurite, malachite, red lead, litharge, orpiment, hematite, iron oxide, cinnabar, vermilion, indigo, lake indigo, kaolin, lead white, oyster shell white 6) painted plates : azurite, malachite, red lead, litharge, orpiment, hematite, iron oxide, cinnabar, vermilion, indigo, lake indigo, kaolin, lead white, oyster shell white. Conditions of tests were that after samples were exposed to 10 times of promoted concentration for 9 months in relative humidity $55{\pm}1%$ and temperature $20{\pm}2^{\circ}C$, they were compared with standards. Items of estimation were color difference(${\Delta}E^*$) and tenacity. After exposure to pesticides, undyed silk cotton ramie fabrics and Korean papers were not nearly changed in their colors, but colors of most of dyed samples were clearly changed by pesticides except for partial samples(acorn- and madder-dyed fabrics etc, gardenia-dyed samples). Especially changes of colors of turmeric-dyed silk fabrics were most distinct. And colors of pigments and painted plates containing lead, copper, arsenic, mercury and vegetable pigments, were clearly changed. Tenacities of yams of undyed silk fabrics were not nearly changed and undyed cotton fabrics were a little reduced as compared with standards. But tenacities of yams of dyed silk and cotton fabrics were clearly reduced or increased as compared with standards. Especially, madder-dyed silk fabrics were increased 10% or more and indigo-dyed silk fabrics were reduced 10% or less in all pesticides. Also madder- and sappanwood(alum post mordancy)-dyed cotton fabrics were increased 10% or more in all pesticides.

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A Study on the Effective Controlling System of Radio-activity Ventilation (RI사용 의료기관의 효율적인 배기관리 방안)

  • Lee, Kyung-Jae;Lee, Jin-Hyung;Kim, Kyung-Hoon;Kwack, Dong-Woo;Jo, Hyun-Duck;Ko, Kil-Man;Park, Young-Jae;Lee, In-Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.12 no.1
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    • pp.91-98
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    • 2008
  • Purpose: Radio-isotopes (RI) use has been steadily developing due to industrial and technical development in the modern medical society. Particularly, popularization of domestic cyclotrons dramatically enable hospitals to produce and use diagnostic radio-isotopes. Generally, only specific facilities such as hospitals, research institutes, nuclear power plants and universities can use radio-isotopes, they are also responsible for ventilation system. The strength of radioactivity in the air is strongly regulated and controlled by korea atomic energy law in Korea Institue of Nuclear Safety (KINS), so that air radioactivity exposure can lead to environmental pollution surrounding places. In this study, we'd like to find out the investigation and the present condition of the controlled ventilation system in domestic hospitals by an emission standard from KINS, and try to reach an agreement about how to use the ventilation system. Result: Definition of filters, features and structures of pre-filters, hepa-filters, charcol filters, filter exchange procedures and precautions are explained. RI deflation concentration and filter exchange cycle have been presented as a standard prescribed in the rules of KINS. The Radiation Control Management System (RCMS) introduced by Seoul National University Bundang Hospital linking to digital pressure gauge with computer controller in another medical facilities were described in details. Conclusions: The system of medical facilities using RI has been remarkably developing in 21 century. Especially, radiation safety control system has also been grown rapidly into the subdivision, specialization, advanced technology along with international technical improvement. However, As far as current RI ventilation system is concerned, it has nothing better than doing in the past. Preferentially, to reinforce this, more sophisticated system with strict periodic filter exchange and exhaust air control guidance should be introduced by applying brilliant domestic information technology for RCMS and digital gauge method. From personal point of view as a radiation safety manager, I have provide with present problems and improvements. Futhermore, more improved guidance should be conducted.

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