• 제목/요약/키워드: pre-evaluation

검색결과 2,086건 처리시간 0.03초

Efficacy and safety of radioiodine therapy for 10 hyperthyroid cats: a retrospective case series study in South Korea

  • Yeon Chae;Jae-Cheong Lim;Taesik Yun;Yoonhoi Koo;Dohee Lee;Mhan-Pyo Yang;Hakhyun Kim;Byeong-Teck Kang
    • 대한수의학회지
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    • 제64권2호
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    • pp.10.1-10.9
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    • 2024
  • Hyperthyroidism, characterized by elevated thyroid hormone levels and thyroid gland hyperplasia or adenoma, is a prevalent endocrinopathy in older cats. Treatment options include antithyroid drugs, surgical thyroidectomy, and radioiodine therapy (RAIT), which is non-invasive treatment option that can achieve complete remission. However, efficacy and safety of RAIT in hyperthyroid cats have not been investigated in South Korea. This study includes 10 hyperthyroid cats with RAIT. Initial assessments comprised history, physical examination, blood analysis, and serum total T4 (tT4) concentration. Thyroid scintigraphy revealed hyperactivity and enlargement of thyroid gland at 24 hours before the RAIT. Radioiodine (RAI) was injected subcutaneously with 2 to 6 mCi, determined by the fixed dose or the scoring system based on severity of clinical signs, tT4 concentration, and thyroid size individually. After RAIT, the concentration of serum tT4 and liver enzymes were significantly decreased at discharge. However, no significant differences were noted in blood urea nitrogen, creatinine, symmetric dimethylarginine, hematocrits, and white blood cell counts pre- and post-treatment. Although 4 cats received RAI twice, clinical signs disappeared and tT4 levels decreased following the RAIT. All 10 cats achieved complete remission after 6 months without critical adverse effect. The safety and the effectiveness of RAIT was confirmed based on protocols reported other countries. Therefore, RAIT could be considered the treatment option and prevent adverse effects from medication or surgery. This preliminary study presents the first evaluation of RAIT for hyperthyroid cats using locally produced RAI in South Korea and provide valuable insight for clinicians and further studies.

특수교사양성과정에서 현장실습학기제 모형개발 기초연구: 교육실습의 이론적 고찰 (A Fundamental Inquiry into The Development of a Framework Implementing Fieldwork in Special Education Teacher Preparation Programs)

  • 한민경;이주영
    • 문화기술의 융합
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    • 제10권4호
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    • pp.259-270
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    • 2024
  • 본 논문은 교육실습 이론에 대한 고찰을 바탕으로 특수교육 교사 교육 프로그램에서 현장실습학기제 모형개발을 위한 기초연구이다. 교육실습이론의 주요단계인 준비, 적응, 책임 준비, 상호 책임, 평가의 특징을 분석하고, 협력, 실용적인 훈련 및 피드백 교환의 중요성을 확인하였다. 또한, 학습 경험 모델인 체험학습 모델, 사회문화 이론 및 관찰의 견습생 모델을 비롯한 실용적 학습 모델을 검토하며, 선행 특수교육 교사들 사이에서 이론과 실무를 연결하고반성적 실천을 촉진하는 역할에 대해 살펴보았다. 더불어, Class-Academy 모델과 PDS 모델 등 두 가지 주요 실습모델을 살펴보고, 이들의 구성, 이점 및 교사 교육 프로그램에 미치는 영향을 논의하였다. 현장실습학기제를 통해 구조화된 실습 경험과 혁신적 모델을 통해 특수교육 교사 교육을 강화하는 방안에 대한 통찰을 제공하고자 하였다.

집중력 회복이론을 통한 지역거주민들의 대학캠퍼스 이용실태 및 만족도 (A Study on the Utilization and Satisfaction of Local Residents in College Campus with the Attention Restoration Theory)

  • 이시영;박군
    • 한국조경학회지
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    • 제42권4호
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    • pp.37-47
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    • 2014
  • 본 연구는 외부이용자를 대상으로 근린공원과 대학캠퍼스의 이용실태와 만족도 그리고 회복환경지각척도를 이용한 조사 및 비교 분석을 통해, 대체녹지로서의 캠퍼스 녹지공간에 대한 치유적 환경으로서의 역할을 파악하고자 하였다. 본 연구를 위해 먼저 문헌연구로서, 선례연구 및 관련 연구문헌들을 조사하여 이론에 대한 적용가능성을 살펴보았다. 그리고 실증연구로서 근린공원과 대학캠퍼스 오픈스페이스 공간의 이용현황을 파악하고, 조성된 시설과 환경에 대해서 이용자들의 만족도를 분석하였다. 또한 근린공원과 캠퍼스 오픈스페이스 공간이 치유적 환경으로서의 타당성과 신뢰성을 측정하고, 이러한 특질이 이용 만족도에 미치는 영향을 파악하였다. 연구 결과, 치유환경 기여도 분석에서 모두 평균 4점 이상으로 상대적으로 높은 기여도를 나타냈다. 이는 도시민들이 스트레스가 넘쳐나는 현대에 사람과 자연의 관계를 더욱 중요하게 느낀다는 것을 실제로 증명하고 있음을 보여준다. 집중력 회복이론은 캠퍼스보다는 근린공원의 경우에서 더 높은 설명력을 보여주었다. 요인분석 결과, 회복환경지각척도 구성 요인과의 유사성은 캠퍼스에서 더 높게 나타났다. 회복환경지각척도에 따른 분석에서 경관의 치유적 특질은 대학캠퍼스 오픈스페이스 공간의 평가에 유용하게 이용될 수 있으며, 치유적 특질을 이용하면 새로운 측면에서 인공 경관을 평가 할뿐만 아니라, 경관개선 방안도 다양한 각도에서 마련될 수 있을 것으로 보인다.

전력계통 운영조건을 고려한 발전기차단용 SPS 동작설정에 관한 연구 (A Study on Setting SPS for Generator Tripping Action considering Operating Conditions of Power Systems)

  • 권한나;손혁진;국경수;양성채
    • 한국산학기술학회논문지
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    • 제15권1호
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    • pp.411-417
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    • 2014
  • 발전기차단용 고장파급방지장치(SPS; Special Protection Scheme)는 대규모 발전단지의 인출 송전선로 고장시 발전단지 내의 발전기 과속을 방지하기 위해 사전에 계획된 대수만큼 해당 발전기를 즉시 차단하여 전력계통 전체의 안정도를 유지하는 비상 장치이다. 그러나 기존의 국내 발전기차단용 SPS 동작은 첨두부하를 기준으로 산정된 값을 일률적으로 적용하여 운영 되고 있어 경부하시에 발전기차단용 SPS가 동작을 하게 되면 발전기 과차단으로 인한 발전력 부족을 초래할 가능성이 있는 등 SPS 운영의 비효율성이 잠재되어있다. 이를 위해 본 논문에서는 수시로 변화하는 전력계통 운영조건을 주기적으로 취득하고 정확도와 속도가 우수한 COA기반의 안정도평가를 통해 발전기 차단용 SPS 동작을 설정함으로써 경부하시에는 SPS 발전기 탈락대수가 첨두수요 기준의 설정치보다 감소되어 계통 고장에 의한 SPS 동작 시 발전비용 증가를 경감 할 수 있다.

하악지 시상분할 절단술 후 감각 변화에 관한 연구 (CLINICAL STUDY OF SENSORY ALTERATIONS AFTER SAGITTAL SPLIT RAMUS OSTEOTOMY)

  • 최준영;유준열;윤보근;임대호;신효근;고승오
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제32권2호
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    • pp.141-148
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    • 2010
  • The bilateral sagittal split ramus osteotomy (BSSRO) is preferred method of surgical correction for mandibular prognathism, retrognathism and asymmetry. This technique performed from primarily an intraoral incision to avoid a scar. After forward movement of the distal segment of the mandible, healing of bone by primary or secondary intention is easily accomplished through large areas of cancellous bony overlap. When rigid fixation is used for the BSSRO, it is possible to open the mouth during the immediate post-operative period because it promotes the healing process. Although this surgical procedure has been well-documented, the incidence of postoperative trigeminal neurosensory disorder in the region of the inferior alveolar nerve and the mental nerve remains one of the major complication. However, evaluation of objective methods for sensory recovery patterns is insufficient although most patients find their sensory return. Neurometer electrodiagnostic device performs automated neuroselective sensory nerve conduction threshold evaluation by determining current perception threshold (CPT) measures. The purpose of this study was to evaluate the sensory recovery patterns of inferior alveolar and mental nerve over time. Nerve examination with a neurometer was performed in 30 patients undergoing the BSSRO at pre-operative, post-operative 1-, 2-, 4- week, and 2-, 3-, 4-, 5-, 6- month follow-up visits after the osteotomy to compare the differences of nerve injury and recovery patterns after the BSSRO with or without genioplasty and sensory recovery patterns associated with the kind of nerve fiber.

관절염 환자를 위한 건강증진 프로그램의 개발 -총체적 모델의 적용- (Development of Health Promotion Program for Individuals With Arthritis -Application of Holistic Model-)

  • 오현수;김영란
    • 대한간호학회지
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    • 제29권2호
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    • pp.314-327
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    • 1999
  • In this study, domains, contents, and effects of pre-existed intervention programs for individuals with arthritis were meta-analyzed to develop arthritis health promotion program based on Holistic Model. The developed program includes strategies of cognition, environment, and behavior. and also generates positive changes in the physical, psychological, and social demensions. Then needs assessment on conveniently selected 153 women who visited a university hospital in Seoul or in Inchon are conducted to identify the objective domains of arthritis health promotion program According to the study results. target health problems of the arthritis health promotion program were shown as pain, disability, depression, and role impediment in social domain. These objectives could be achieved by including the strategies of changing cognition, the strategies of changing behavior through learning the skill related to the health promoting behavior. and the strategies of changing environment in the health promotion program. That is, it is analyzed that the contents of program are not exclusive one another in physical. psychological. and social demensions, and also are not exclusive one another in aspect of cognition, behavior, and environment. The necessary methods to achieve the desired objectives for the developed arthritis health promotion program and evaluation subjects are as follows : (1) In the arthritis health promotion program, knowledge on management of arthritis, efficacy related to arthritis management, skill for pain management, skill for exercise, establishment of positive self-concept, enhancement of positive thinking, stress management. skill for problem solving, skill for setting goals. skill for requesting help, and skill for communication are all included. Through the improvement of all those strategies, intermediate objectives, such as “joint protection, and maintenance of pain management behavior”, “maintenance of regular exercise”, and “promotion of coping skill in psychosocial dimension” are achieved. (2) These intermediate objectives are also the methods for achieving objectives in next stage. It implies that through the intermediate objectives. the final objectives such as “minimization of physical symptoms and signs”, “maximization of psychological function”, and “maximazation of role performance in social domain” could be achieved. Each of these final objectives reflects the different dimension of quality of life, respectively. When these objectives are achieved, the quality of life that client perceives is improved. Therefore, through evaluation of these final objectives, the level of achieving final outcome of arthritis health promotion such as quality of life is determined.

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방폭구조 ESD Detector 개발 및 본질안전 특성 분석에 관한 연구 (A Study on the Development of Explosion Proof ESD Detector and Intrinsic Safety Characteristics Analysis)

  • 변정환;최상원
    • 한국안전학회지
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    • 제35권1호
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    • pp.1-11
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    • 2020
  • Article 325 (Prevention of Fire Explosion due to Electrostatic) of the Rule for Occupational Safety and Health Standard specifies that in order to prevent the risk of disasters caused by static electricity, fire, explosion and static electricity in the production process, However, in order to do this, it is absolutely necessary to use a pre-detection technology and a detector for antistatic discharge prediction, which is a precautionary measure by static electricity in a fire / explosion hazard place, but in Korea, And there is no technical standard for the application of the technology of the explosion proof structure of the related equipment. Research methods include domestic and overseas electrostatic discharge detection technology and literature investigation of related equipment explosion proofing technology, domestic and foreign electrostatic discharge detection device production and use situation investigation, advanced foreign technology data analysis and benchmarking. In particular, we sought to verify the results of empirical experiments using electrostatic discharge detection technology through sample purchase and analysis of related major products, development of optimization technology through prototype production, evaluation, and supplementation, and expert knowledge through expert consultation. The results of this study were developed and fabricated two prototypes of electrostatic discharge detector based on the technology / standard related to electrostatic discharge detection technology in Korea and abroad through development of electrostatic discharge detection technology and development and production of detector. In addition, based on the development of electrostatic discharge detection technology, we developed an intrinsic safety explosion proof ib class explosion proof technology applicable to the process of using and handling flammable gas and flammable liquid vapor and combustible dust. In the case of the over voltage and minimum voltage are supplied to the explosion-proof structure ESD detector, check the state of the circuit and the transient and transient currents generated by the coil and capacitor elements during the input and standby of the signal pulse voltage. Explosion-proof equipment-Part 11: Intrinsically safe explosion proof structure The comparative evaluation with the reference curve in Annex A of "i" confirms that the characteristics of the intrinsically safe explosion protection structure are met.

인공강우기 기반 확률강우재현을 통한 식생유니트형 LID시스템의 우수유출지연 효과분석 (Analysis of Rainfall Runoff Delay Effect of Vegetation Unit-type LID System through Rainfall Simulator-based Probable Rainfall Recreation)

  • 김태한;박정현;최부헌
    • 한국환경복원기술학회지
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    • 제22권6호
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    • pp.115-124
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    • 2019
  • In a climate change environment where heat damage and drought occur during a rainy season such as in 2018, a vegetation-based LID system that enables disaster prevention as well as environment improvement is suggested in lieu of an installation-type LID system that is limited to the prevention of floods. However, the quantification of its performance as against construction cost is limited. This study aims to present an experiment environment and evaluation method on quantitative performance, which is required in order to disseminate the vegetation-based LID system. To this end, a 3rd quartile huff time distribution mass curve was generated for 20-year frequency, 60-minute probable rainfall of 68mm/hr in Cheonan, and effluent was analyzed by recreating artificial rainfall. In order to assess the reliability of the rainfall event simulator, 10 repeat tests were conducted at one-minute intervals for 20 minutes with minimum rainfall intensity of 22.29mm/hr and the maximum rainfall intensity of 140.69mm/hr from the calculated probable rainfall. Effective rainfall as against influent flow was 21.83mm/hr (sd=0.17~1.36, n=20) on average at the minimum rainfall intensity and 142.27mm/hr (sd=1.02~3.25, n=20) on average at the maximum rainfall intensity. In artificial rainfall recreation experiments repeated for three times, the most frequent quartile was found to be the third quartile, which is around 40 minutes after beginning the experiment. The peak flow was observed 70 minutes after beginning the experiment in the experiment zone and after 50 minutes in the control zone. While the control zone recorded the maximum runoff intensity of 2.26mm/min(sd=0.25) 50 minutes after beginning the experiment, the experiment zone recorded the maximum runoff intensity of 0.77mm/min (sd=0.15) 70 minutes after beginning the experiment, which is 20 minutes later than the control zone. Also, the maximum runoff intensity of the experiment zone was 79.6% lower than that of the control zone, which confirmed that vegetation unit-type LID system had rainfall runoff reduction and delay effects. Based on the above findings, the reliability of a lab-level rainfall simulator for monitoring the vegetation-based LID system was reviewed, and maximum runoff intensity reduction and runoff time delay were confirmed. As a result, the study presented a performance evaluation method that can be applied to the pre-design of the vegetation-based LID system for rainfall events on a location before construction.

최소 절개 기법에 의한 아킬레스건 파열의 수술적 봉합술 (Surgical Repair of Achilles Tendon Rupture by Minimal Incision Technique)

  • 정홍근;백호동
    • 대한족부족관절학회지
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    • 제9권2호
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    • pp.173-178
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    • 2005
  • Propose: There have been many debates about the ideal surgical technique for acute Achilles tendon rupture. The purpose of this study is to review and analyze the clinical outcome of the acute Achilles tendon ruptures that had been repaired by indirect suture technique with minimal incision that utilized an instrument called Achillon (Newdeal, France). Materials and Methods: This study is based on the 14 cases (14 patients) of acute Achilles tendon total ruptures that have been repaired by minimal incision technique utilizing Achillon instrument from June 2003 to December 2004. Two cases were reruptured before 8 weeks and repaired again using Krackow suture which left 12 feet for postoperative functional evaluation with at least 6 months of follow-up. Ten cases were men and average age at time of injury was 34.4 (26-49) years. The time from injury to surgery was an average of 4.5 (1-9) days and the postoperative evaluations were done by an Arner-Lindholm scale and AOFAS score. The ability to return to original work and sports activities as well as patient satisfaction were also evaluated. Results: The follow-up period was averaged for 13.2 (6-24) months. Seventy-one percent of cases were ruptured during sports activities. The ruptured level was the average of 5.1 cm (3.2-8 cm) above calcaneal attachment and the skin incision was averaged for 2.7 cm (2.5-3.0 cm) long. At final follow-up, standing on tip-toe was possible in all cases while the heel-floor height on ruptured side was shorter by 0.7 cm (0-2 cm). By Arner-Lindholm evaluation scale, 9 cases were excellent, and 3 cases were good. Overall AOFAS score was an average of 96.1 (94-100), and all patients were satisfied with the result. Patients returned to work at an average of 1.3 months after the surgery and pre-injury sports activities were all possible from at 6 months after operation. Conclusion: Since we have treated acute Achilles tendon ruptures with minimal incision technique utilizing the Achillon and gained encouraging functional results with all patients returning to previous work with high patient satisfaction, this technique could be recommended as one of the ideal surgical options for the Achilles tendon ruptures.

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발효과정에서 생성되는 발효유제품의 안식향산 함량 수준 평가 (Evaluation of Benzoic Acid Level of Fermented Dairy Products during Fermentation)

  • 임상동;박미선;김기성;유미영
    • 한국축산식품학회지
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    • 제33권5호
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    • pp.640-645
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    • 2013
  • 본 연구는 발효과정 중 생성되는 발효유제품의 안식향산을 조사함으로써 축산식품관리 정책의 기초자료로 활용하기 위하여 실시하였다. 축산물의 가공기준 및 성분규격의 축산물 시험법 중 전처리 방법인 Sep-Pak을 이용한 분석방법과 자동증류장치를 이용한 분석방법 중 1개를 택일하기 위하여 유제품의 회수율을 측정한 결과 커다란 차이가 없음에 따라 전처리 시간이 짧은 Sep-Pak을 이용한 분석방법을 선정하였다. Sep-Pak법의 유효성 검증으로 안식향산의 검량선은 $R^2$ = 0.999로 양호한 직선성을 나타냈으며, 검출한계는 0.058 mg/kg, 정량한계는 0.176 mg/kg을 보였다. 완제품에서 검출된 발효유를 대상으로 공정 단계별로 안식향산을 분석한 결과 스타터를 첨가한 이후 단계에서 2.28-10.48 mg/kg 수준이었고 첨가제(시럽)에서는 검출되지 않았으며, 시중 유통 중인 발효유는 0-16.5 mg/kg으로 나타났다. 치즈의 경우 카멤베르 치즈는 커드형성 후, 가공치즈는 원료치즈에서 영향을 많이 받는 것으로 나타났고, 시중 유통 중인 자연치즈는 0-4.2 mg/kg, 가공치즈는 0-20.8 mg/kg으로 나타났다. 이러한 결과를 토대로 원료, 제조과정 중 및 완제품 전과정에서 발생될 수 있는 자연유래 안식향산을 일관성 있고 체계적으로 관리할 수 있는 기초자료로 활용할 것으로 사료된다.