• Journal of Nutrition and Health
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• v.32 no.5
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• pp.561-569
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• 1999

In the atherosclerotic subjects, arterial endothelial cell injury and plaque formation are suspected to be strong causable factors in developing acute coronary syndrome, and it was revealed that platelets have a very important role in this case. Women are exposed to atherosclerosis at a different degree after menopause or oral contraception. The purpose of this study was to determine the effects of endogenous and exogenous estrogen on the degree of platelet aggregation in platelet rich plasma(PRP) in twenty nonsmoking healthy Korean women for 12 weeks. The subjects were assigned to three groups: (1) eight women aged 49 to 60(yr) for the postmenopausel(Pst) group, (2) eight, aged 22 to 30(yr) for the premenopausa(Pre) group, (3) four, aged 23 to 30(yr) for the oral contraceptive (OC) group which used triphasic OC formulation. Fasting blood sample were obtained from the subjects, (1) once per 6 weeks in the Pst group, (2) every phase of the menstrual cycle in the Pre group, (3) each once during and after OC administration in the OC group. ADP, collagen and epinephrine were used as aggregating reagents, and platelet aggregation and time(Δt: time reaching to the maximum point of aggregation) in PRP were measured at the maximum point of aggregation in five minutes. All the data were adjusted for dietary effects, personality type and body mass index(BMI) by using analysis of covariation(ANCOVA). Platelet aggregation to ADP and collagen(MADP and MCOLL) were not significantly different among the three groups, and Δt to ADP and collagen(TADP and TCOLL) were not either. But maximum platelet aggregability and Δt to epinephrine(MEPIN and TEPIN) were significantly different among the three groups, and the OC group showed the lowest value (p<0.01). Maxtimum platelet aggregability and Δt during the menstrual cycle were not significantly different in the Pre group. Any other significant differences in the maximum platelet aggregability and Δt were found between oral contraception phase and washing out phase(menstruation) in the OC group. In results, maximum platelet aggregability and aggregation time to ADP and collagen seemed not to be affected by endogenous and exogenous estrogen, even though MEPIN and TEPIN showed significantly low in the OC group among the three groups.

• Macromolecular Research
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• v.11 no.4
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• pp.241-249
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• 2003

A molecular-thermodynamic model to describe the salt-induced protein precipitation is developed based on the perturbation theory. We employed the modified perturbed hard-sphere-chain (PHSC) equation of state for copolymer mixtures to take into account the pre-aggregation effect among protein particles. Hypothetical pressure-composition diagrams are computed with various size differences and salt concentrations. The precipitation behaviors are also studied for various types of pre-aggregation effect for the given systems.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.5B
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• pp.326-333
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• 2008

In wireless sensor networks, a sensor node with in-network aggregation adjusts the timeout which is a waiting time to receive messages from child nodes. This paper proposes a novel timeout scheduling scheme for data aggregation in wireless sensor networks, which adaptively configures its timeout according to changing data patterns in order to improve energy efficiency and data accuracy during data aggregation. The proposed scheme decreases the timeout when the temporal difference of collected data(data variation) from children is lower than a pre-defined threshold because there is no occurrence of critical events. Conversely, it increases the timeout when the data variation is higher than the pre-defined threshold in order to fulfill more accurate data aggregation. Extensive simulation reveals that the proposed scheme outperforms the cascading-based scheme in terms of energy consumption and data accuracy.

• Journal of Korea Multimedia Society
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• v.9 no.11
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• pp.1421-1434
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• 2006

Spatial data warehouses provide analytical information for decision supports using SOLAP (Spatial On-Line Analytical Processing) operations. Many researches have been studied to reduce analysis cost of SOLAP operations using pre-aggregation methods. These methods use the index composed of fixed size nodes for supporting the concept hierarchy. Therefore, these methods have many unused entries in sparse data area. Also, it is impossible to support the concept hierarchy in dense data area. In this paper, we propose a dynamic pre-aggregation index method based on the spatial hierarchy. The proposed method uses the level of the index for supporting the concept hierarchy. In sparse data area, if sibling nodes have a few used entries, those entries are integrated in a node and the parent entries share the node. In dense data area, if a node has many objects, the node is connected with linked list of several nodes and data is stored in linked nodes. Therefore, the proposed method saves the space of unused entries by integrating nodes. Moreover it can support the concept hierarchy because a node is not divided by linked nodes. Experimental result shows that the proposed method saves both space and aggregation search cost with the similar building cost of other methods.

• Macromolecular Research
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• v.11 no.1
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• pp.53-61
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• 2003

A molecular-thermodynamic model is developed for the salt-induced protein precipitation. The protein molecules interact through four intermolecular potentials. An equation of state is derived based on the statistical mechanical perturbation theory with the modified Chiew's equation for the fluid phase, Young's equation for the solid phase as the reference system and a perturbation based on the protein-protein effective two body potential. The equation of state provides an expression for the chemical potential of the protein. In a single protein system, the phase separation is represented by fluid-fluid equilibria. The precipitation behaviors are simulated with the partition coefficient at various salt concentrations and degree of pre-aggregation effect for the protein particles. In a binary protein system, we regard the system as a fluid-solid phase equilibrium. At equilibrium, we compute the reduced osmotic pressure-composition diagram in the diverse protein size difference and salt concentrations.

• YAKHAK HOEJI
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• v.56 no.6
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• pp.382-389
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• 2012

Effects of citrate-capped silver nanoparticles (AgNPs) on the blood coagulation and platelet aggregation were investigated using whole blood, platelet rich plasma (PRP) and washed platelet obtained from SD male rats. To confirm the stability of AgNPs in the test, size distribution of the nanoparticles was measured in the vehicles including distilled water, serum, and platelet buffers. The average size of AgNPs was 20 nm in the vehicles, which means that the stability was maintained during the whole experimental period. When blood coagulation was monitored by using whole blood impedance aggregometer, coagulation was not observed at the concentration of 1, 10 and 50 ppm. Platelets in plasma or in buffer were not aggregated by AgNPs at the concentration of 1, 2 and 4 ppm, respectively. The test concentration of AgNPs could not be increased because the dark color of the nanoparticles impeded the transmission of light, which is an indicator of aggregation. Although the blood or platelets were pre-activated by collagen, thrombin, or ADP with sub-threshold level, aggregation was not observed at the test concentration. Microscopic observation also supported the result obtained by the aggregometer.

• Journal of information and communication convergence engineering
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• v.3 no.1
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• pp.13-17
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• 2005

The link e daggregation between 10GbE switches requires an advanced framistribution method to be properly and efficiently applied. The fixed or dynamic frame distribution methods, formerly proposed, cannot fully utilize the aggregated links, where the receiving terminal only attaches to a pre-specified link among multiple physical links. A frame distribution method using padding is proposed for the link aggregation between 10GbE switches to solve this problem. We compared the performance of the proposed method with those of the static and dynamic frame distribution methods. As a result, the proposed method shows a better performance when the offered load is below 0.7 and the average length of the frames is longer than 954 bytes.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.27 no.2
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• pp.173-180
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• 2003

Effects of the electric conductivity of particles were studied for the aggregation process of charged particles with a Brownian dynamic simulation in the free molecular regime. A periodic boundary condition was used for the calculation of the aggregation process in each cell with 500 primary particles of 16 nm in diameter. We considered two extreme cases, a perfect conductor and a perfect nonconductor. The electrostatic force on a particle in the simulation cell was considered as a sum of electrostatic forces from other particles in the original cell and its replicate cells. We assumed that aggregates were only charged with pre-charged primary particles. The morphological shape of aggregates was described in terms of the fractal dimension. The fractal dimension for the uncharged aggregate was D$_{f}$= 1.761. However, the fractal dimension decreased from 1.694 to 1.360 for the case of the perfect conductor, and from 1.610 to 1.476 for the case of the perfect nonconductor, with the increase of the average number of charges on the primary particle from 0.2 to 0.3. These values were smaller than that of the centered charge case.e.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.12A
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• pp.945-950
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• 2003

The link aggregation between 10GbE switches requires an advanced frame distribution method to be properly and efficiently applied. The fixed or dynamic frame distribution methods, formerly proposed, cannot fully utilize the aggregated links, where the receiving terminal only attaches to a pre-specified link among multiple physical links. A frame distribution method using tagging is proposed for the link aggregation between 10GbE switches to solve this problem. We compared the performance of the proposed method with those of the fixed and dynamic frame distribution methods. As a result, the proposed method shows a better performance when the applied load is below 0.7 and the average length of the frames is longer than 954 bytes.

• Journal of Korea Spatial Information System Society
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• v.12 no.1
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• pp.10-17
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• 2010

Sensor nodes used in Geosensor network are resource limited and power constrained. So it is necessary to research on routing protocols to gather data by using energy efficiently. Wireless sensor networks collect data gathered from sensor nodes by transfering it to the sink using multihop. However, it has two problems. First, the existing works require unnecessary data transmission for choosing a proper parent node to transfer data. Secondly, they have a large number of data transmission because each sensor node has a different path. To solves the problems, we, in this paper, propose a designated path based data aggregation scheme for efficient energy management in WSNs. The proposed scheme can reduce unnecessary data transmission by pre-determining a set of paths and can enable all the sensor nodes to participate in gathering data by running them in round-robin fashion. We show from performance analysis that the proposed scheme is more energy efficient than the existing directed diffusion(DD) and the hierarchical data aggregation(HDA).