• Title/Summary/Keyword: ppb levels

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Dietary Risk Assessment for Polycyclic Aromatic Hydrocarbons in Foods (식품중 Polycyclic Aromatic Hydrocarbons의 위해성평가)

  • 이효민;윤은경;박경아;김윤희;정소영;권기성;김명철;송인상;이철호
    • Journal of Food Hygiene and Safety
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    • v.19 no.1
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    • pp.1-8
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    • 2004
  • This study was executed to determine the cumulative dietary risk of PAHs exposed by food ingestion. Food samples including barbecued beef, barbecued pork, grilled chicken, ham, bacon and vegetable oil which were collected from food markets. These samples were saponified, extracted and cleaned up to purify PAHs, and then the purified sample solutions were analyzed by HPLC-FL. Generally, the levels of total PAHs in barbecued beef (0.2 ppb), bacon (0.3 ppb), barbecued pork (0.7 ppb), ham (0.8 ppb), and vegetable oil (1.2 ppb) were low, whereas the level of total PAHs in grilled chicken (9.3 ppb) was significantly high. For the exposure assessment of PAHs due to food ingestion, PAHs levels converted into TEQ$_{BaP}$, the average body weight for 20-73 age group and consumed levels of food proposed from report on the National Health and Nutrition Survey were used. The estimated lifetime average daily intake of dietary PAHs was 4.32${\times}$10$^{-4}$ $\mu\textrm{g}$-TEQ$_{BaP}$kg/day as the mean value. The dietary risk adjusted to cancer potency of benzo(a)pyrene as 7.3 (mg/kg/day)$^{-1}$ was 3.44${\times}$10$^{-6}$ based on current data.ata.

Analysis of Residual Furan in Human Blood Using Solid Phase Microextraction-Gas Chromatography/Mass Spectrometry (SPME-GC/MS)

  • Lee, Yun-Kyung;Jung, Seung-Won;Lee, Sung-Joon;Lee, Kwang-Geun
    • Food Science and Biotechnology
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    • v.18 no.2
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    • pp.379-383
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    • 2009
  • For an accurate risk assessment of furan, a potential human carcinogen, levels must be determined in human blood plasma using a simple and robust assay. In this study, solid phase microextraction-gas chromatography/mass spectrometry (SPME-GC/MS) was used to analyze blood plasma levels of furan in 100 healthy individuals who consumed a normal diet. The subjects were 30 to 70 years of age and 51% were women. Ultimately, an analytical method was established for analyzing furan in human blood. The limit of quantification (LOQ) and furan recovery rate in blood were 1.0 ppb and 104%, respectively. Finally, furan was detected in 21 individuals (13 males, 8 females) with levels ranging up to 17.86 ppb (ng furan/g food).

Analysis of Peanut and Peanut Butter Retailed in Korea for Aflatoxin $B_1$ (국내 시판 땅콩 및 땅콩버터 중 Aflatoxin $B_1$ 오염 분석)

  • Park, Je-Won
    • Korean Journal of Food Science and Technology
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    • v.38 no.2
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    • pp.309-312
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    • 2006
  • Aflatoxin $B_1$ in 70 retail samples, including 40 food-grade peanut (28 domestic, 12 imported) and 30 peanut butter (12 domestic, 18 imported) samples, was analyzed by high-performance liquid chromatography (HPLC) with fluorescence detection (FD), and positive samples were confirmed using HPLC with mass spectrometry (MS). Recoveries of aflatoxin $B_1$ spiked at 2 ppb exceeded 80% in both commodities. Detection limits for aflatoxin $B_1$ by HPLC-FD and MS analysis were 0.8 and 0.1 ppb, respectively. Four domestic and six imported peanut samples contained detectable levels of aflatoxin $B_1$ with means of 19 and 32 ppb, respectively. Aflatoxin $B_1$ was found in two domestic and three imported peanut butter samples with mean aflatoxin $B_1$ of 10 and 12 ppb, respectively. Peanut commodity showed more frequent aflatoxin $B_1$ contamination compared to its processed peanut butter product, and levels of aflatoxin $B_1$, especially in imported peanuts, were significantly (p<0.05) higher than those of other commodities. These results suggest peanut and peanut butter are not major contributors to dietary intake of aflatoxin $B_1$ in South Korea.

Ability of Modified Glucomannan to Sequestrate T-2 Toxin in the Gastrointestinal Tract of Chicken

  • Reddy, N.B.;Devegowda, G.;Shashidhara, R.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.2
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    • pp.259-262
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    • 2004
  • The ability of Modified Glucomannan (MG) to bind T-2 toxin (T-2) in the gastrointestinal tract has been tested in vivo by feeding 120 five-wk-old broiler chicken with the following six treatment diets, 1) Control diet; 2) Control+MG (0.1%); 3) Control+T-2 (500 ppb); 4) Control+T-2 (500 ppb)+MG (0.1%); 5) Control+T-2 (1,000 ppb) and 6) Control+T-2 (1,000 ppb)+MG (0.1%). Twenty birds were assigned to each treatment group, which had five experimental groups. Four birds of each experimental group were sacrificed at an interval of 30 min i.e. at 0, 30, 60, 90 and 120 min after feeding experimental diets. The whole gut contents of each bird were collected, dried and toxin concentration was determined. Percent T-2 recovered from the gut was significantly lower (p<0.05) in the groups fed MG at all the time intervals. The percent T-2 adsorbed by the MG at different T-2 levels (500 and 1,000 ppb) was 15.97 and 14.77, 22.53 and 22.67, 26.88 and 28.03, and 31.50 and 31.83 at 30, 60, 90 and 120 min, respectively.

Regional Background Levels of Carbon Monoxide Observed in East Asia during 1991~2004 (1991~2004년 동아시아에서 관측한 일산화탄소의 지역적 배경 농도)

  • Kim, Hak-Sung;Chung, Yong-Seung
    • Journal of the Korean earth science society
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    • v.27 no.6
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    • pp.643-652
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    • 2006
  • Data of the carbon monoxide concentration observed in Mt. Waliguan in China (WLG), Ulaan Uul in Mongolia (UUM), Tae-ahn Peninsula in Korea (TAP), and Ryori in Japan (RYO) were analyzed for a long period between 1991 and 2004. The annual average concentration of carbon monoxide was the highest at TAP $(233{\pm}41ppb)$ followed by $RYO(171{\pm}36ppb),\;UUM(155{\pm}26ppb),\;and\;WLG(135{\pm}22ppb)$. The seasonal variations being high in spring and low in summer were observed in other areas of Eastern Asia except WLG. TAP was high in carbon monoxide concentration in all seasons compared to WLG, UUM and RYO and shows wide distribution of concentration in the histogram, which is caused by the influence of large-scale air pollution due to its downwind location close to the East Asian continent, China in particular. Also, our data was compared with data measured at Mauna Loa (MLO) in Hawaii. According to the origin of the isentropic backward trajectory and its transport passage, carbon monoxide concentration observed in TAP was analyzed as follows: continental background airflows (CBG) were $216{\pm}47ppb$; regionally polluted continental airflows (RPC) were $316{\pm}56ppb$; Oceanic background airflows (OBG) were $108{\pm}41ppb$; and Partly perturbed oceanic airflows (PPO) were $161{\pm}6ppb$. The high concentration of carbon monoxide in TAP is due to the airflow from East Asian continent origin rather than that from the North Pacific origin. Especially, RPC which passes through the eastern China appeared to be the highest in concentration in spring, fall, and winter. However, OBG was affected by the North Pacific air mass with a low carbon monoxide concentration in summer. The NOAA satellite images and GEOS-CHEM model simulation confirmed a large-scale air pollution event that was in the course of expansion from southeastern China bound to the Korean Peninsula and the Korea East Sea by way of the Yellow Sea.

Effects of Chromium Picolinate (CrP) on Growth Performance, Carcass Characteristics and Serum Traits in Growing-Finishing Pigs

  • Min, J.K.;Kim, W.Y.;Chae, B.J.;Chung, I.B.;Shin, I.S.;Choi, Y.J.;Han, I.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.1
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    • pp.8-14
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    • 1997
  • An experiment was carried out to evaluate the effects of feeding graded levels of chromium in the form of chromium picolinate on growth performance, blood components, carcass grade, in vitro lipogenesis and lipolysis, and in vitro protein degradation and synthesis in growing-finishing pigs. There were no significant differences for daily weight gain, feed intake and feed conversion among treatments during growing phase, while in the finishing phase, feed intake was lower in groups fed diets with 200 ppb chromium than in other treatment (p < 0.1). Feed conversion was improved in the groups fed diets with chromium compared with control. Carcass weight was similar among treatments while carcass length was longer in groups fed diets with 200 ppb chromium (p < 0.05). Thinner carcass fat was found with groups fed diets with chromium compared to control. Three A grade of carcasses were from groups fed chromium compared to control. No significant differences were observed with blood glucose, insulin, total cholesterol, triglycerides and non-esterified fatty acid at 60kg body weight. While, at 100 kg body weight, blood triglyceride was lower in groups with 200 and 400 ppb chromium but higher in groups with 100 ppb chromium (p < 0.05). In vitro lipolysis and protein synthesis in adipose tissues were increased as dietary chromium was increased from 0 to 200 ppb (p < 0.1). As a result, 200 ppb chromium in a growing-finishing diet could improve feed efficiency and carcass traits; an increase to 400 ppb has no further effect.

Associations between Air Pollution and Asthma-related Hospital Admissions in Children in Seoul, Korea: A Case-crossover Study (환자교차 설계 방법을 적용한 소아천식 입원에 대한 도시 대기오염의 급성영향평가)

  • Lee, Jong-Tae
    • Journal of Preventive Medicine and Public Health
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    • v.36 no.1
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    • pp.47-53
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    • 2003
  • Objectives : I used a case-crossover design to investigate the association between air pollution, and hospital admissions for asthmatic children under the age of 15 years in Seoul, Korea Methods : I estimated the changes in the levels of hospitalization risk from theinterquartile (IQR) increase in each pollutant concentrations, using conditional logistic regression analyses, with controls for weather information. Results : Using bidirectional control sampling, the results from a conditional logistic regression model, with controls for weather conditions, showed the estimated relative risk of hospitalization for asthma among children to be 1.04 (95% confidence interval (CI), 1.01-1.08) for particulate matter with an aerodynamic diameter less than or equal to 10m (IQR=40.4ug/m3); 1.05 (95% CI, 1.00- 1.09) for nitrogen dioxide (IQR=14.6ppb): 1.02 (95% CI,0.97-1.06) for sulfur dioxide (IQR=4.4ppb): 1.03 (95% CI, 0.99-1.08) for ozone (IQR=21.7ppb): and 1.03 (95% CI, 0.99-1.08) for carbon monoxide f10R=1.0ppm). Conclusions : This empirical analysis indicates the bidirectional control sampling methods, by design, would successfully control the confounding factors due to the long-term time trends of air pollution. These findings also support the hypothesis that air pollution at levels below the current ambient air quality standards of Korea is harmful to sensitive subjects, such as asthmatic children.

Investigation of benzimidazole residues in the meat in Sejong area (세종지역 유통 식육 중 벤지미다졸계 구충제 잔류실태 조사)

  • Kim, Tae Pyoung;Kim, Tae Won;Lee, Jong Hoon;Kim, Mun-Bae
    • Korean Journal of Veterinary Service
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    • v.44 no.3
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    • pp.125-131
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    • 2021
  • Benzimidazole is an widely used anthelmintics in livestock clinics. The aim of present study was to investigate benzimidazole residues in the meat in Sejong City. A total of 338 samples of meat(beef 287, pork 37, chicken 14) were selected from the laboratory meat(Korean beef genetic test, hygiene test) supplied to school in Sejong City. Representative benzimidazole class drug such as thiabendazole, 2-amino albendazole sulfone, fenbendazole, oxfendazole, and oxfendazole sulfone were monitored in samples by using lc-ms/ms and the analysis was preformed based on the Korea Food Code guideline. Limit of quantitation (LOQ) was ranged from 0.56 to 3.02 ppb for target drugs and the accuracy was within the acceptance criteria. Among the sample analyzed only one case, the pork meat was found to have drug levels that exceed LOQ. However, the overall residue concentration was 2.17 ppb, which was lower than the maximum residue levels (100 ppb).

Bioaccumulation of copper and zinc by the giant kelp Macrocystis pyrifera

  • Evans, La Kenya;Edwards, Matthew S.
    • ALGAE
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    • v.26 no.3
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    • pp.265-275
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    • 2011
  • This study examined the bioaccumulation of the heavy metals copper (Cu) and zinc (Zn) by the giant kelp, Macrocystis pyrifera, by exposing meristematic kelp tissue to elevated metal concentrations in seawater within laboratory aquaria. Specifically, we carried out two different experiments. The first examined metal uptake under a single, ecologically-relevant elevation of each metal (30 ppb Cu and 100 ppb Zn), and the second examined the relationships between varying levels of the metals (i.e., 15, 39, 60, 120, 240, and 480 ppb Cu, and 50, 100, 200, 300, 500, and 600 ppb Zn). Both experiments were designed to contrast the uptake of the metals in isolation (i.e., when only one metal concentration was elevated) and in combination (i.e., when both metals' concentrations were elevated). Following three days of exposure to the elevated metal concentrations, we collected and analyzed the M. pyrifera tissues using inductively coupled plasma atomic emissions spectroscopy. Our results indicated that M. pyrifera bioaccumulated Cu in all treatments where Cu concentrations in the seawater were elevated, regardless of whether Zn concentrations were also elevated. Similarly, M. pyrifera bioaccumulated Zn in treatments where seawater Zn concentrations were elevated, but this occurred only when we increased Zn alone, and not when we simultaneously increased Cu concentrations. This suggests that elevated Cu concentrations inhibit Zn uptake, but not vice versa. Following this, our second experiment examined the relationships among varying seawater Cu and Zn concentrations and their bioaccumulation by M. pyrifera. Here, our results indicated that, as their concentrations in the seawater rise, Cu and Zn uptake by M. pyrifera tissue also rises. As with the first experiment, the presence of elevated Zn in the water did not appear to affect Cu uptake at any concentration examined. However, although it was not statistically significant, we observed that the presence of elevated Cu in seawater appeared to trend toward inhibiting Zn uptake, especially at higher levels of the metals. This study suggests that M. pyrifera may be useful as a bio-indicator species for monitoring heavy metal pollution in coastal environments.

Evaluation of Polychlorinated Biphenyls(PCBs) and Organochlorine Insecticide Residues in Irrigation Waters in the Periphery of Suwon (수원근교(水原近郊) 관개수중(灌漑水中)의 PCBs 및 유기염소계(有機鹽素系) 살충제(殺蟲劑)의 잔류평가(殘留評價))

  • Lee, Youn-Hyung;Hwang, Eul-Chul;Park, Chang-Kyu
    • Korean Journal of Environmental Agriculture
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    • v.4 no.2
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    • pp.95-101
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    • 1985
  • Water samples collected monthly between November 1982 and October 1983 from seven reserviors and a river in the periphery of Suwon, Korea were subjected to gas chromatographic analysis for PCBs and organochlorine insecticide residues. PCBs were positively detected in the most samples. The average residue levels of PCBs were found in the range of 0.009${\sim}$0.5 ppb while those of organochlorine insecticides were in the range of "not detected"${\sim}$0.008 ppb. The ratio of average residue levels of PCBs to those of total DDT was found to vary with sampling sites. The highest ratio of 500 was found in the water samples of Han River and the lowest in water of Won-chun Reservior. Both industrial and urban waste appear to be responsible for PCBs in the irrigation waters.

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