• Journal of Pharmaceutical Investigation
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• v.30 no.2
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• pp.133-138
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• 2000

Terbinafine is an orally active antifungal agent as it inhibits the fungal enzyme squalene epoxidase, which is important in the early biosynthetic pathway of ergosterol. This leads to abnormal development of the fungal cell membrane. Bioequivalence of two terbinafine tablets, $Lamisil^{TM}$ (Novartis Korea Ltd.) and $Terbina^{TM}$ (Korean Drug Co., Ltd.), was evaluated according to the guidelines of Korea Food and Drug Administration (KFDA). Sixteen normal male volunteers, $23.56{\pm}1.75$ years old and $65.60{\pm}8.54\;kg$ of body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one tablet containing 125 mg of terbinafine was orally administered, blood was taken at predetermined time intervals and the serum concentrations of terbinafine were determined using an HPLC method with UV detector. The pharmacokinetic parameters $(AUC_t,\;C_{max}\;and\;T_{max})$ were calculated and ANOVA test was utilized for the statistical analysis of parameters. The results showed that the differences in $AUC_t,\;C_{max}\;and\;T_{max}$ between two tablets based on $Lamisil^{TM}$, tablet were -2.53%, -2.98% and 8.13%, respectively. The powers $(1-{\beta})$ for $AUC_t,\;C_{max}\;and\;T_{max}$ were 85.21%, 98.21% and 93.11%, respectively. Minimum detectable differences $({\Delta})$ at ${\alpha}=0.1\;and\;1-{\beta}=0.8$ were all less than 20%. The 90% confidence intervals were all within ${\pm}20%$. All the parameters above met the criteria of KFDA for bioequivalence, indicating that $Terbina^{TM}$ tablet is bioequivalent to $Lamisil^{TM}$ tablet.

• Journal of the Korean association of regional geographers
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• v.22 no.4
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• pp.745-760
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• 2016

The name of a place represents the social and political power relations as well as showing a certain physical space. In particular, the East Sea is not only a representative name of areas represent our country, but also the name of place being in competition with the Sea of Japan internationally. Korea is committed in many ways to spread the name of East Sea in the international community, and gradually expand its name power. The purpose of this study was to investigate the names used in the newspapers and broadcasting in Francophone countries except France by analyzing the newspaper articles and broadcasting contents, and to illuminate how the names of the East Sea produced in France, and the discussion about the names were diffused in Francophone countries and what kind of influence they had on those countries. This study selected Algeria in North Africa, Belgium and Luxembourg in West Europe, and Quebec in Canada for the research areas. As a result, while Algeria in North Africa and Luxembourg are showing inhospitality to the name East Sea, Belgium and Quebec are taking a flexible attitude toward this name. In general, most Francophone countries are provided with press releases from AFP in France. Even in same article provided by AFP, The result shows that some media stick to use the name Sea of Japan solely, and others demonstrate a will to use both name East Sea and Sea of Japan simultaneously. This study was able to show that the diffusion and spread of the place name was significantly influenced by social, political interests and powers, the mess geopolitics in pop cultural materials.

• Applied Biological Chemistry
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• v.41 no.7
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• pp.516-521
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• 1998

Solubility patterns and gelatinization properties of two waxy rice starches, Sinsunchalbyeo and Hwasunchalbyeo, were investigated. Shapes of all starch granules were round and polygonal, and their X-ray diffraction patterns were all A type. Amylose content and water binding capacity of Sinsunchalbyeo were similar to those of Hwasunchalbyeo. The swelling powers and solubilities of two starches were increased with increasing temperature in range of $65{\sim}95^{\circ}C$, and those of Hwasunchalbyeo was higher. Iodine affinities of soluble fractions in Sinsunchalbyeo starch were higher than those in Hwasunchalbyeo at the same temperature and both were increased with increasing temperature. λmax of soluble fraction of Sinsunchalbyeo starch was highest at $75^{\circ}C$ of heating temperature. The transmittance of starch suspensions were increased rapidly at $60{\sim}65^{\circ}C$. By Rapid Visco Analyzer, initial gelatinization temperature of Sinsunchalbyeo was $67.2^{\circ}C$, and that of Hwasunchalbyeo was $68.2^{\circ}C$. In DSC analysis, onset temperature for gelatinization of Sinsunchalbyeo and Hwasunchalbyeo were $61.3^{\circ}C\;and\;62.9^{\circ}C$, respectively.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.8
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• pp.1868-1876
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• 2010

In this paper, we design a 256-bit EEPROM IP using only logic process-based devices. We propose EEPROM core circuits, a control gate (CG) and a tunnel gate (TG) driving circuit, to limit the voltages between the devices within 5.5V; and we propose DC-DC converters : VPP (=+4.75V), VNN (-4.75V), and VNNL (=VNN/3) generation circuit. In addition, we propose switching powers, CG_HV, CG_LV, TG_HV, TG_LV, VNNL_CG, VNNL_TG switching circuit, to be supplied for the CG and TG driving circuit. Simulation results under the typical simulation condition show that the power consumptions in the read, erase, and program mode are $12.86{\mu}W$, $22.52{\mu}W$, and $22.58{\mu}W$ respectively. Furthermore, the manufactured test chip operated normally and generated its target voltages of VPP, VNN, and VNNL as 4.69V, -4.74V, and -1.89V.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.1153-1163
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• 2015

The purpose of this study is to investigate the effects of task-oriented activities on hand functions in patients with hand injuries. From December 2011 to October 2012, sixteen patients with hand injuries at C Hospital in Changwon, Gyeongsangnam-do, Korea were randomly divided into two groups. One group was subjected to task-oriented activity and the other to general exercise. Two groups performed each activity once a day, three times a week, for four weeks. The group with the task-oriented activities was provided with the tasks according to subject-preference based on the result of Canadian Occupational Performance Measure (COPM). To verify the effect of intervention, the following hand function measures were used: grip strength, pinch strength, and the range of opposition and abduction, Purdue pegboard test and Disabilities of the Arm, Shoulder and Hand (DASH). Both groups showed significant increase in all of the hand function measures after 4-week activities(p<.05). The task-oriented activity group was significantly different from the control group in powers for tip pinch, lateral pinch and three-jaw chuck pinch, Purdue pegboard test and DASH(p<.05) except in grip strength and the range of opposition and abduction suggesting better improvement in hand functions. This study shows that task-oriented activities improve the hand functions more effectively in patients with hand injuries.

• The Journal of Korean Physical Therapy
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• v.15 no.1
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• pp.82-95
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• 2003

Our health is intimately connected to the health of our environment. The contemporary world view which sees a radical distinction between humans as subjects and world as object can obscure our recognition of how much we rely on nature for health and survival. Indigenous traditions and contemporary scholars remind us that we live in a universe in which all things are connected, and in which nature continues to offer its gifts in co-creative partnership for the health and wellbeing of all. Living in awareness of our relationship with nature enables us to open more to the experience of nature's nurturing. Many complementary therapies derive from ancient practices that involve nature in healing partnership. Essential oils have been used for thousands of years. Hippocrates claimed that the way to health was through aromatic baths and massages. Much anecdotal evidence exists regarding aromatherapeutic positive effects on recipients. Aromatherapy is a branch of complementary or alternative therapy which is increasing in popularity, yet has scant scientific credibility. Aromatherapy should be defined as treatment using odors and practised as such. However, essential oils are usually used in conjunction with therapeutic massage and often combined with counselling of some kind. Aromatherapy complements and enhances the therapeutic powers of massage. Massage is one of the most wonderful ways to relax and is throughly beneficial to health. Massage can help unknot tense and aching muscles and other minor symptoms of stress, leaving patients fresh and energized. As the use of aromatherapy within a health care setting has grown so rapidly in recent years, and will continue to do so, the need for suitable training has become apparent. No health service can afford the risk of having staff who are inadequately trained in the practice of aromatherapy using essential oils incorrectly on those in a state of ill-health, especially if the essential oils used are not to a standard suitable for therapeutic use. Training to an acceptable level in aromatic therapy is essential for safety and effectiveness. Knowledge of the nature and make-up of essential oils, their effect on the body and the emotions, and how, when, and where to apply them is imperative in order for them to be beneficial to a patient's health. In order to achieve best practice, further research is necessary to explore the use of aromatherapy in the management of multiple disorder.

• Land and Housing Review
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• v.2 no.4
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• pp.439-452
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• 2011

The goal of this research is to suggest the desirable directions of the land policies implement system based on analysis of existing those of Korea with the paradigm shift of land policies. We classify the land policies into land ownership, land use, land development and land management ones, and then analyze their implement system characteristics. The results are follows : firstly, the land policies implement systems have been set to large scale and rapid development. Secondly, although the systems have been specialized by their areas, the comprehensive manage systems for the harmony between development and conservation are lacking. Thirdly, the parts of the central government powers related to land use has been hand covered to local governments. And the participations of residences private companies have enlarged in the land development. Fourthly, the purposes of the information management on land use have been changed from tax collection into planned land use, but the information management has not met the need of planned land use. This study shows that firstly, the implement system focusing on large development projects might be no longer effective because of high possibility of the property prices stabilization, so moderately small ones must be found. Secondly, the system cope with the climate change and to realize the efficient utility of land is needed. Thirdly, it is necessary to take the actual measures to participate a variety of subjects. Fourthly, the system modification of the land information manage system as land policies infra is also needed to establish integral land policies.

• Journal of Internet Computing and Services
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• v.15 no.2
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• pp.19-31
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• 2014

In this paper, a parallel backoff delay procedure on multiple IEEE 802.15.4 channels and a channel searching method considering the frequency spectrum of WiFi traffic are studied for IEEE 802.15.4 nodes to avoid the interference from WiFi traffic. In order to search the channels being occupied by WiFi traffic, we analyzed the methods measuring the powers of adjacent channels simultaneously, checking the duration of measured power levels greater than a threshold, and finding the same periodicity of sampled RSSI data as the beacon frame by signal processing. In an wireless channel overlapped with IEEE 802.11 network, the operation of CSMA-CA algorithm for IEEE 802.15.4 nodes is explained. A method to execute a parallel backoff procedure on multiples IEEE 802.15.4 channels by an IEEE 802.15.4 device is proposed with the description of its algorithm. When we analyze the data measured by the experimental system implemented with the proposed method, it is observed that medium access delay times increase at the same time in the associated IEEE 802.15.4 channels that are adjacent each other during the generation of WiFi traffic. A channel evaluation function to decide the interference from other traffic on an IEEE 802.15.4 channel is defined. A channel searching method considering the channel evaluations on the adjacent channels together is proposed in order to search the IEEE 802.15.4 channels interfered by WiFi, and the experimental results show that it correctly finds the channels interfered by WiFi traffic.

• Korean journal of food and cookery science
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• v.22 no.5 s.95
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• pp.659-665
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• 2006

The effects of resistant starches on the quality characteristics of cookies were investigated by the physicochemical, instrumental and sensory properties of RS-added flours and cookies. Retrograded RS3 by autoclaving-cooling cycle and cross-linked RS4 after annealing treatment were used. The protein content of RS-added flour decreased, but the ash content of RS4-added flour increased slightly with increasing RS content. The RS levels of wheat flour, RS3- and RS4-added flours were 7.0%, 9.6-13.4% and 11.5-17.9%, respectively. The swelling powers of RS-added flours at 80$^{\circ}C$ decreased, but the solubility of RS3-added flour increased by 2-3 fold compared to that of control flour. Initial pasting temperature increased, but peak, holding, and final viscosities decreased with increasing RS content. The retrogradation degree of RS-added flours was lowered, because of the decreased consistency and breakdown viscosity. The yellowness of RS3-added flour increased with increasing RS3 content which induced browning reaction during baking. On the sensory test, RS-added cookies were significantly different in shape, color and overall quality (p<0.05), and their texture also affected. Overall quality was higher in peanut cookies than in AACC standard cookies and RS addition (up to 30%, w/w), regardless of the RS type, improved the cookie quality.

• Korean Journal of Food Science and Technology
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• v.30 no.4
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• pp.787-793
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• 1998

Physicochemical properties of starch of three cultivars of Korean kidney Bean Starches, Pink (PKB), Red (RKB) and White (WKB) were studied. Starch granule was oval/round and smooth in all samples. The amylograms showed a continuous increase of viscosity without peak during heating. The water-binding capacities of starches of PKB, RKB and WKB were 102.1%, 94.7% and 106.9%, respectively. The swelling powers were rapidly incresed in all samples. The amylose content, blue value and relative viscosity of kidney bean starches were $31.1{\sim}32.8%,{\;}0.64{\sim}0.66$ and $2.27{\sim}2.61{\;}mlg^{-1}$, respectively. The transmittance of starch suspension was linearly increased as the temperature raised from $65^{\circ}C{\;}to{\;}85^{\circ}C$. The gelatinization temperature ranges determined by differential scanning calorimetry (DSC) were $71.1{\sim}86.9^{\circ}C for PKB, $71.1{\sim}86.0^{\circ}C$ for RKB and $60.8{\sim}77.9^{\circ}C$ for WKB.