• Asian Pacific Journal of Cancer Prevention
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• v.16 no.11
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• pp.4623-4628
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• 2015

Breast cancer still remains as the most frequent cancer with second mortality rate in women worldwide. There are no validated biomarkers for detection of the disease in early stages with effective power in diagnosis and therapeutic approaches. Cancer/testis antigens are recently promising tumor antigens and suitable candidates for targeted therapies and generating cancer vaccines. We conducted the present study to analyze transcript changes of two cancer/testis antigens, OIP5 and TAF7L, in breast tumors and cell lines in comparison with normal breast tissues by quantitative real time RT-PCR for the first time. Significant over-expression of OIP5 was observed in breast tumors and three out of six cell lines including MDA-MB-468, T47D and SKBR3. Not significant expression of TAF7L was evident in breast tumors but significant increase was noted in three out of six cell lines including MDA-MB-231, BT474 and T47D. OIP5 has ssignificant role in chromatin organization and cell cycle control during cell cycle exit and normal chromosome segregation during mitosis and TAF7L is a component of the transcription factor IID, which is involved in transcription initiation of most protein coding genes. TAF7Lis located at X chromosome and belongs to the CT-X gene family of cancer/testis antigens which contains about 50% of CT antigens, including those which have been used in cancer immunotherapy.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.8
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• pp.1200-1205
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• 2002

Construction of Private networks is becoming easier due to the openness of telecommunication market, rapidly developing telecommunication technology. The size of existing private networks is becoming huge which resulted in surplus of capacity of the networks. These trends will generate a problem of efficient use of national telecommunication resources and which will be a factor for the structure of domestic telecommunication market which will have a big impact on the existing telecommunication carriers. Therefore, national policy of private network issues should be considered along with the national efforts for the information infrastructure, control of telecommunication market, fairness of competition, strength Power of national competition. In this paper it will be suggested that the efficient policy on the issue of domestic private network, by analyzing present situation, status quo, laws, regulation and procedure for domestic private networks and comparing it with those of U.S.A, Japan, EU.

• Journal of Advanced Marine Engineering and Technology
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• v.36 no.4
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• pp.445-450
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• 2012

At the limited space, the air conditioning may have difficult to control temperature or humidity for home use. Nowdays, the people reponse to temperature or humidity sensitively. This becomes the Indoor Air Quality (IAQ) is an important factor for comfortably. Heat recovery ventilator (HRV) is used for the solution of inconsistency between IAQ and power-saving. Also, the thermoelectric element is applied to HRV and compared with temperature efficiency and verifying the capacity of the system. To improve the temperature efficiency a single motor and thermoelectric element with the conductive guide vane is experimented. The results shows that it can save 23 W by using the single motor. The developed system of 250 CMH capacities with the thermoelectric element reveals the temperature efficiency improvement of 4.01% in cooling period and 2.98% in heating period compared to the conventional system.

• Architectural research
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• v.13 no.3
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• pp.31-40
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• 2011

Profit-keeping behaviors naturally occur in the market to satisfy consumers, and the logic behind it lies in the economies of scale. On the flip side, some commodities transacted in the market are not available or can not be easily acquired unless the demand is high enough. Under this proposition, some consumers rise and find their own solution to meet the services at a reasonable cost or at an adequate level. The commonly adopted way is to establish a cooperative, and it stirs purchasing power by pooling resources and further bargains price and service quality. As a consumer cooperative, housing cooperatives notably found in rural towns enable the elderly to continue independent living. This study is to take a closer look at residential life of the rural elderly in housing cooperatives. Utilizing in-depth focus group interviews with 40 residents in four housing cooperatives, this qualitative research draws main factors affecting the decision to move in, residential assessment, and strengths and weakness of living in a housing cooperative. The primary factor influencing the moving decision is to continue to independent living in a familiar community, and the bottom line is planning ahead. Frailty and bereavement are found to be the leading occasions for them to move. The participants are satisfied with the independent living arrangement, and particularly, cited such features as safety and security, elderly-friendly design, common spaces, freedom, social activities and efficient living. Also, it is stated that some cooperative natures such as control over the property and giving a voice on management render positive impacts on the satisfaction with communal living. In spite of all the benefits and strengths, participants face with a public notion that an independent living arrangement like a housing cooperative has never done before in rural towns, so that most people recognize it as part of dependent living arrangements like nursing home.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3943-3947
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• 2012

Objective: Findings for associations between the methylenetetrahydrofolate reductase (MTHFR) A1298C gene polymorphism and head and neck cancer risk have been conflicting. We therefore performed a meta-analysis to derive a more precise relationship. Methods: Ten published case-control studies were collected and odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the association between MTHFR A1298C polymorphism and head and neck cancer risk. Sensitivity analysis and publication bias assessment also were performed to guarantee the statistical power. Results: Overall, no significant association between MTHFR A1298C polymorphism and head and neck cancer risk was found in this meta-analysis (C vs. A: OR=1.04, 95%CI=0.87-1.25, P=0.668, Pheterogeneity<0.001; CC vs. AA: OR=1.07, 95%CI=0.70-1.65, P=0.748, $P_{heterogeneity}<0.001$; AC vs. AA: OR=1.06, 95%CI=0.88-1.27, P=0.565, $P_{heterogeneity}<0.001$; CC+AC vs. AA: OR=1.06, 95%CI=0.86-1.30, P=0.571, $P_{heterogeneity}<0.001$; CC vs. AA+AC: OR=1.02, 95%CI=0.69-1.52, P=0.910, $P_{heterogeneity}<0.001$). Similar results were also been found in succeeding analysis of HWE and stratified analysis of ethnicity. Conclusion: In conclusion, our meta-analysis demonstrates that MTHFR A1298C polymorphism may not be a risk factor for developing head and neck cancer.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.2 s.245
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• pp.202-209
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• 2006

As the economic power is improved and the customer's demand is hard to please, the noise and vibration is the most important yardstick that can determine the quality of the product. Especially, as the airconditioner's demand increase suddenly, the product of quality and the noise is becoming a decisive factor of determining whether purchase the product or not. Therefore, every manufactory is investing a lot of money and research to cut down the unpleasantness induced from noise and vibration. And they are emphasizing their product's difference by advertising a silence very actively. With these reason, the demand of a silent indoor air-conditioner is the essential research filed when the product is develop(:d. In this study, the noise and vibration is visualized in the space and frequency domain by using experimental methods such as operational deflection shape (ODS), modal testing and sound intensity. Also the location of noise source and its characteristic is analyzed in an acoustical point of view to reduce the structure borne noise that come from the fan motor, and the pertinent control method is suggested. Furthermore, the most suitable shape of the motor bracket is suggested by applying FEM and DOE (Design of experiments) in the noise and vibration point a view.

• Journal of Satellite, Information and Communications
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• v.5 no.2
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• pp.57-63
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• 2010

Many efficient frequency sharing methods are issued in present because of increasing users with various wireless communication terminals. In the satellite communications, the service coverage is generally very wide so frequency sharing with terrestrial system is essentially needed, and the research is progressing dynamically related on this frequency sharing method. But if we adopt the terrestrial system which is commonly used, it can't avoid the interference from terrestrial service to satellite service. Therefore, this paper will introduce methods for reducing the interference from terrestrial station to earth station using cognitive radio system Satellite system is guaranteed with decreasing interference from terrestrial stations using Genetic Algorithm based power control method. Furthermore, terrestrial systems can have increased QoS because the frequency reuse factor in proposed method is higher than existing methods.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.48 no.12
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• pp.73-81
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• 2011

As high speed digital systems continue to use components with faster edge rate and clock speeds, transmission of the digital information, it can bring about many troubles. The increasing requirement for controlled impedance PCBs becomes both a critical success factor and a design challenge to implement a system. Especially, the noise sources in high frequency digital systems include the noise in power supply, ground and packaging, and they destroy the fidelity of signals. Therefore PCB design with impendence matching is needed to improve fidelity of signal in H/W. In this paper, we have developed an impedance control and analysis tool for multi-layer PCB design, and simulates the tracks controlled impedance with the test coupon. So, it can save the design time and support the economical PCB design.

• Journal of IKEEE
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• v.24 no.1
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• pp.319-325
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• 2020

In this paper, a discontinuous-conduction mode (DCM) DC-DC buck converter is presented for mobile device applications. The buck converter consists of compensator for stable operations, pulse-width modulation (PWM) logic, and power switches. In order to achieve small hardware form-factor, the number of off-chip components should be kept to be minimum, which can be realized with simple and efficient frequency compensation and digital soft start-up circuits. Burst-mode operation is included for preventing the efficiency from degrading under very light load condition. The DCM DC-DC buck converter is fabricated with 0.18-um BCDMOS process. Programmable output with external resistors is typically set to be 1.8V for the input voltage between 2.8 and 5.0V. With a switching frequency of 1MHz, measured maximum efficiency is 92.6% for a load current of 100mA.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2002.11a
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• pp.63-69
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• 2002

Construction of Private networks is becoming easier due to the openness of telecommunication market, rapidly developing telecommunication technology. The size of existing private networks is becoming huge which resulted in surplus of capacity of the networks. These trends will generate a problem of efficient use of "national telecommunication resources" and which ill be a factor for the structure of domestic telecommunication market which will have a big impact on the existing telecommunication carriers. Therefore, national policy of private network issues should be considered along with the national efforts for the information infrastructure, control of telecommunication market, fairness of competition, strength power of national competition. In this paper it will be suggested that the efficient policy on the issue of domestic private network, by analyzing present situation, status quo, laws, regulation and procedure for domestic private networks and comparing it with those of U.S.A, Japan, EU.apan, EU.