• Proceedings of the Korean Society of Applied Pharmacology
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• 2008.04a
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• pp.23-30
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• 2008

Mitochondria biogenesis requires a coordination of two genomes, nuclear DNA (nDNA) and mitochondrial DNA (mtDNA). Disruption of mitochondria function leads to a loss of mitochondrial membrane potential and ATP generating capacity and consequently results in chronic degenerative diseases including insulin resistance, metabolic syndrome and neurodegenerative diseases. Although PPAR-${\gamma}$ coactivator-$1{\alpha}$ (PGC-$1{\alpha}$) was discovered as a central regulator of mitochondria biogenesis and a transcriptional co-activator of nuclear respiratory factor (NRF) and mitochondrial transcription factor A (Tfam), the expressions of PGC-$1{\alpha}$, NRF and Tfam were not significantly altered in tissues showing abnormal mitochondria functions. This observation suggests that there should be another regulator(s) for mitochondria function. Here, we demonstrate microRNAs (miRNAs) can modulate mitochondria function. Overexpression of microRNA dissipated mitochondrial membrane potential and increased ROS production in vitro and in vivo. It will be discussed the target of microRNA and its role in metabolic syndrome.

• Journal of the Korean Chemical Society
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• v.32 no.2
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• pp.94-102
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• 1988

A quantitative description of the principle of least motion is suggested. The reaction path function of electronic variables, its norm and the reaction path average energy, which are unique for a given reaction path on a potential energy surface of a reacting system, are defined and their characteristics are discussed. It is postulated that the norm of the function and the average energy can be used as a criterion for identification of the preferred path of a unimolecular isomerization reaction. For a molecule with a certain symmetry, the preferred path, with which Woodward-Hoffmann rule agrees, is immediately identified without laborious computation.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.35T no.3
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• pp.67-75
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• 1998

This paper presents a new robot motion planning method for moving obstacle avoidance. To consider the mobility of a moving obstacle, we define virtual distance function(VDF) between the robot and the obstacle. At each sampling time, we use the VDF to construct an artificial potential, considering the motion of obstacles. The robot moves according to the repulsive and attractive force vector induced by the artificial potential function. The proposed algorithm can be driven the robot to avoid moving obstacles in real time. Some simulation studies show the effectiveness of the proposed method.

• Bulletin of the Korean Chemical Society
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• v.3 no.2
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• pp.44-49
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• 1982

Dynamic and equilibrium structures of a polymer chain immersed in solvent molecules have been investigated by a molecular dynamic method. The calculation employs the Lennard-Jones potential function to represent the interactions between two solvent molecules (SS) and between a constituent particle (monomer unit) of the polymer chain and a solvent molecule (CS) as well as between two non-nearest neighbor constituent particles of the polymer chain (CC), while the chemical bond for nearest neighbor constituent particles was chosen to follow a harmonic oscillator potential law. The correlation function for the SS, CS and CC pairs, the end-to-end distance square and the radius of gyration square were calculated by varying the chain length (= 5, 10, 15, 20). The computed end-to-end distance square and the radius of gyration square were found to be in a fairly good agreement with the corresponding results from the random-flight model. Unlike earlier works, the present simulation rsesult shows that the autocorrelation function of radius of gyration square decays slower than that of the end-to-end distance square.

• Journal of applied mathematics & informatics
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• v.7 no.2
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• pp.575-583
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• 2000

In this work, we solve the Fredholm-Volterra integral equation(FVIE) when the kernel takes a potential function form under given conditions. we represent this kernel in the Weber-sonin integral form.

• Journal of the Korean Mathematical Society
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• v.44 no.6
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• pp.1233-1241
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• 2007

We derive a kind of weighted norm inequalities which relate the commutators of potential type operators to the corresponding maximal operators.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.1
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• pp.10-18
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• 2007

We synthesize and analyze the optical transfer function(OTF) of the modified triangular interferometer(MTI) using two-pupil synthesis method and we present the optimal MTI, which can obtain any bipolar function by combining a wave plate and a linear polarizer. Also, we analyze its potential phase error sources caused by polarization components.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.2
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• pp.291-297
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• 2012

In this paper, potential field algorithm was used for path planning in dynamic environment. This algorithm is used to plan a robot path because of its elegant mathematical analysis and simplicity. However, there are some problems. The problems are problem of collision risk, problem of avoidance path, problem of time consumption. In order to solve these problems, we fused potential field with fuzzy system. The input of the fuzzy system is set using relative velocity and location of robot and obstacle. The output of the fuzzy system is set using the weighting factor of repulsive potential function. The potential field algorithm is improved by using fuzzy potential field algorithm and, path planning in various environment has been done.

• Bulletin of the Korean Chemical Society
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• v.26 no.7
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• pp.1083-1089
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• 2005

Most experimental studies available in the literature on filtration are based on observed average zeta potential of particles (usually 10 measurements). However, analyses of data using the average zeta potential alone can lead to misleading and erroneous conclusions about the attachment behavior because of the variation of particle zeta potentials and the heterogeneous distribution of the collector surface charge. To study characteristics of zeta potential, zeta potential distributions (ZPDs) of silica particles under 9 different chemical conditions were investigated. Contrary to many researchers’ assumptions, most of the ZPDs of silica particles were broad. The solids concentration removal was better near the isoelectric point (IEP) as many researchers have noticed, thus proper destabilization of particles is very important to achieve better particle removal in particle separation processes. While, the mean zeta potential of silica particles at a given coagulant dose was a function of particle concentration; the amount of needed coagulant for particle destabilization was proportional to the total surface charge area of particles in the suspension.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.22 no.3
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• pp.27-33
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• 2008

This paper deals with the assessment of potential interference between individual grounding electrodes using an Electrolytic Tank Modeling method. When a test current was passed through a grounding electrode, potential rise was measured and analyzed using an electrolytic tank in real time. In order to analyze the potential interference between grounding electrodes, a reduced scale modeling method was studied. Potential interference between isolated grounding electrodes was evaluated as a function of the separation distance between grounding electrodes and the configuration of grounding electrode to be induced. It was found that the separation distance between grounding electrodes was a major factor in reducing the potential interference.