• 대한의생명과학회지
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• 제24권1호
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• pp.35-42
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• 2018

Postmortem interval (PMI) is very important in the crime scene investigation. However, it is very difficult to estimate of the interval since death after a decomposition. Recently, there have been various studies on the postmortem interval since a decomposition. In particular, the total body score (TBS) and accumulated degree days (ADD) used to estimate the postmortem interval after a decomposition. This study was conducted with the aim of applying the TBS and ADD to estimate the postmortem interval in real forensic caseworks. In first murder case, TBS was 12 and ADD value was 132, respectively. An estimated time of PMI was around 23:00 on June 21, and the suspect's statement was 01:20 on June 22. Our estimated interval since death and the suspect's statement for the PMI differ by only 2 hours and 20 minutes. In second forensic case, TBS was 3 and ADD value was 55, respectively, an estimated time of PMI was around 02:26 on September 23. The suspect's statement was 10:30 on September 23. Our estimated time and the suspect's statement for the PMI differ by 8 hours. In these cases, we were able to have confirmed the feasibility of TBS and ADD on the real forensic cases. Overall, our finding suggested that the quantitative method could be used to produce PMI estimates that are accurate to within days or even hours.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.121.3-122
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• 2003

This report describes the fatal case of a 13-year-old middle school girl(MSG) whose cause of death might be attributed to a intoxication involving Venlafaxine(VEN). MSG's mother had the history of depression for 11 years. She and her daughter were found dead in the same room of their apartment, with hanged herself. We analyzed the postmortem of MSG which were requested to our institute for the cause of her death. We couldn't get any blood samples from MSG's postmortem. (omitted)

• 한국자기공명학회논문지
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• 제17권1호
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• pp.40-46
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• 2013

For a case study of suspected paraquat intoxication, we developed a simple and rapid method of $^1H$ qNMR to determine the mili-molar amount of paraquat in postmortem blood samples. There were no interfering signals from endogenous compounds in the chemical shift of paraquat and diquat (internal standard). The amount of sample used ranged from 0.25 mM to 10.0 mM. Diquat, which has similar physicochemical properties with paraquat, was chosen as an internal standard. The NMR experimental conditions, relaxation delay time and CPMG spin-echo pulse sequence were optimized. The developed method was validated in terms of specificity, accuracy, precision, matrix effect, recovery, limit of detection (LOD), and low limit of quantification (LLOQ). The proposed qNMR method provided a simple and rapid assay for the identification and quantification of the quaternary ammonium herbicide, "paraquat" in postmortem blood samples. This method was tested by using the blood from the heart of a man who was intoxicated with paraquat. In this particular case, the level of paraquat was 1.07 mM in the blood. For the determination of quaternary ammonium herbicides, qNMR could also be used to provide a better understanding of the currently available techniques.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.216.3-217
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• 2002

• Anatomy and Cell Biology
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• 제56권1호
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• pp.155-159
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• 2023

Studies describing the vascular systems and their variations in Situs inversus totalis (SIT) from a whole-body computed tomographic (CT) angiography perspective are lacking. We report a case of SIT in which postmortem CT angiography (PMCTA) was performed as a part of the forensic death investigation and incidentally detected several vascular variations in it. The PMCTA procedure was performed using the multiphase PMCTA protocol. Almost all major vessels were visualized, indeed in a completely reversed pattern. Contrast mixture flow interruptions were noted in the right coronary arterial branches suggesting possible blockage, upon which autopsy revealed >90% vessel occlusions at several locations. As such the cause of death was due to ischemic heart disease. Anomalous origins of the right internal mammary artery; abnormal left thyrocervical trunk and variations in the drainage of testicular veins were noted. Our findings might be helpful to clinicians and add to the body of literature on SIT.

• 한국동물위생학회지
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• 제33권1호
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• pp.1-6
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• 2010

Monoclonal antibody (mAb)-based enzyme immune-slide assay (EISA) was used for the detection of Peste des petits ruminants (PPR) virus from field samples collected from a natural outbreak. The clinicopathological study was undertaken to diagnose the case primarily of PPR. Antigen was detected from discharges and faeces of infected goats and swabs of postmortem lesions prepared on glass slide or glass plate using acetone fixation. Nasal discharge collected at the early stage of disease course or lung is an appropriate ante- or postmortem sample for this technique, respectively. Convalescent polyclonal sera collected from recovered animals which were diagnosed as PPR by EISA showed high antibody titer against PPR by C-ELISA, demonstrating the satisfactory specificity of the test. Therefore, EISA is a sensitive and specific assay to confirm PPR infection both in field and laboratory conditions and especially suitable for developing country.

• 한국동물위생학회지
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• 제30권2호
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• pp.287-289
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• 2007

Uremia was diagnosed in a slaughtered 20-month old bull. It had no special clinical signs, but many lesions associated with uremia were observed at postmortem inspection. It had a lot of ascites. Kidney, urinary bladder and ureter were enlarged, congested and hemorrhagic, and the incised section of those slightly smelled nasty. However, the precise cause of uremia in this case could not be completely identified.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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• pp.281.2-282
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• 2001

• 대한임상독성학회지
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• 제1권1호
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• pp.34-39
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• 2003

Carisoprodol (CSP) is commonly prescribed as a skeletal muscle relaxant. Recently, we encountered 7 suicidal cases in which carisoprodol was detected. We developed a rugged, sensitive, and specific method for the determination of CSP and meprobamate (MPB) by GC and GC/MS. Postmortem blood concentrations of CSP and MPB ranged 22.9-124.4 ,$\mu$g/ml and its metabolite, 26.8-144.5 ,$\mu$g/ml respectively. Among 7 cases studied, Only CSP was ingested in 4 cases and combination of CSP and dextromethorphan was ingested in 2 cases according to the case history and one case was with ethanol. The order of the tissue concentration of CSP and MPB was liver> kidney > brain, and the concentration of MPB was higher than that of CSP in all tissues. The MPB /CSP concentration ratios of urine, bile juice, liver, kidney, brain and blood were 15.7, 4.0, 1.2, 1.4, 1.4 and 1.0 respectively. There was a big difference in concentration of CSP and MPB in 7 cases due to differences in the amount of dose administered and time to death after dosing.

• Journal of Chest Surgery
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• 제36권10호
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• pp.789-793
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• 2003

원발성 폐동맥 육종은 매우 드문 질환이다 비특이적인 다양한 임상증상과 폐동맥 색전증 등으로 혼돈할 수도 있어 진단이 매우 어렵고, 지연될 수가 있다. 드물지만 원발성 육종이 호발하는 심장, 심막에서의 전이유무나 혹은 원격 전이에 대해서도 주의를 기울여야 한다. 저자들은 기관지 협착을 동반한 원발성 폐동맥 육종에 대해 수술 1예를 경험하였기에 문헌 고찰과 함께 보고하고자 한다.