• Korean Journal of Clinical Pharmacy
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• v.28 no.1
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• pp.40-50
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• 2018

Objective: This study presented the analysis period, the complexity of combined therapy and comparator choice as the key limitations in the economic evaluation of new drugs, and discussed programs for coping with these limitations. Methods: This study evaluated the post-evaluation, risk-sharing agreement, extra funding program, and flexible incremental cost-effectiveness ratio (ICER) threshold as actions or programs that would increase accessibility to costly new drugs. The study also presented the cases of other countries. The application of the post-evaluation was considered to deal with high uncertainty regarding new drugs. Results: The risk-sharing agreement was introduced in European countries as well as South Korea and has been responsible for the shift from using the financial schemes to outcome-based schemes. The drug funding program has had troubled in securing stable extra funds. The application of higher ICER in the economic evaluation of expensive and innovative oncology drugs was criticized because of the inequity between oncology patients and patients with other diseases. Conclusion: Therefore, introducing and applying actions that would increase the accessibility to costly new drugs in South Korea have been deemed necessary after careful reviews and discussions with various stakeholders (insurer, policy makers, pharmaceutical companies and patients).

• Journal of Korea Technology Innovation Society
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• v.1 no.2
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• pp.181-191
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• 1998

우리나라 기술인력 양성의 문제들을 해결하기 위한 방안의 하나로서 일반대학과 별도로 기술인력양성을 전문으로 하는 학위과정 설치의 필요성이 대두되었으며, 1996년 교육개혁의 일환으로 단설대학원제도와 전문학위제도가 시행되기 시작하였다. 그동안 여러 분야에서 단설대학원 설립이 추진되었으며, 일부에서 운영이 시작되고 있으나 과학기술분야에서는 극히 일부의 사례만이 있을 뿐이고 아직 본격적으로 활성화되고 있다고 보기 어렵다. 본고는 공공연구기관에서 시행되는 단설대학원의 사례들을 조사 분석함으로써 우리나라 과학기술계 출연연구기관에서의 바람직한 운영모델을 제시하고자 한다. 일본의 총합연구대학원대학과 연계대학원제도, 중국 국가연구소들의 학위수여제도, 프랑스 국가연구소들의 석 박사과정, 독일 연구기관들의 박사과정 등을 소개하였다. 이어서 우리나라에서 현재 진행되고 있는 단설대학원 설립 추진현황을 분석하고, 각 국의 학위과정 운영사례를 연합대학형, 개별법인형, 겸직교수형, 공동운영형, 연구소 독자운영형의 5가지로 분류하고 각각의 특징을 비교하였다. 끝으로 우리나라 과학기술계 출연연구기관의 단설대학원 설립의 활성화방안으로서 독자운영형, 공동운영형, 연합법인형의 세가지를 제시하고 각 대안의 추진방안을 논의하였다.

• Korean Medical Education Review
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• v.26 no.1
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• pp.5-18
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• 2024

The author recommends the creation of a nationwide career guidance program at the national level through the establishment of a long-term cohort, involving collaboration among medical schools nationwide. This cohort would be constructed for the purpose of analyzing correlations from admission to medical school to post-graduate education, facilitating the development of a career guidance program. This will aid in career development through students' self-analysis and competency building. Each medical school should operate a systematic career guidance program. Career guidance for post-graduate major selection should be included in the regular curriculum. Schools are advised to operate student counseling rooms for various career guidance services. For example, medical schools can operate 1:1 career counseling, academic counseling, career guidance surveys, psychological tests, and counseling. It is advisable to establish a mentor-professor system, connect mentor professors, and build a network of experts related to majors to provide immediate support according to students' needs. Professional mentor training should be provided to mentor professors. To provide opportunities for students to experience their career paths in advance, early clinical exposure, long-term integrated clinical practice, community-based clinical practice, participation in student research programs, career fairs, and student internship programs are recommended. In South Korea, it is necessary to systematically operate the internship system and make improvements to facilitate optical career choices. Additionally, considering the significant influence of social factors on students' career choices in South Korea, efforts should be made to identify and address the issues related to these social factors.

• Korean Journal of Health Education and Promotion
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• v.23 no.3
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• pp.1-16
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• 2006

Objectives: To analyze the characteristics of smoking prevention programs for the adolescent, and to synthesize the common effect sizes on smoking prevention programs for the adolescent. Methods: Seventeen studies for meta-analysis were selected from dissertations, these, and papers that had been published from 1996 to 2005 and had a randomized or nonequivalent control group in a pre test-post test design. The analysis of the data was computed by using the meta-analysis software package developed by Song(2003). Results: Smoking prevention programs for the adolescent have resulted in a significant effect size on smoking-knowledge( .62), smoking-attitude( .55) of smoking prevention programs for the adolescent showed more than 'medium effect' size. In smoking-knowledge and amount of smoking, the effect size was smoking-attitudes, the effect size was large in the studies which consists of more than 10 sessions of intervention. Conclusion: From the above results, we notice that the smoking prevention programs for the adolescent were effective in increasing the smoking-knowledge, smoking-attitudes, and the intention of smoking-cessation.

• Journal of Family Relations
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• v.22 no.4
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• pp.223-238
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• 2018

Objectives: The purpose of this study was a) to examine the effect of positive family relationships on post-traumatic growth in cancer patients, and b) to verify the moderating effect of spiritual sensitivity. Methods: The subjects were cancer patients, both outpatients and inpatients selected from major hospitals specialized in cancer treatment using judgement sampling. A self-administered questionnaire survey was given to cancer patients, and a total of 208 cases were collected but only 201 cases were used in the final analysis due to seven unclear and inadequate questionnaires. We performed descriptive statistics to identify the prevalence for each variable, and the moderating effect was verified through multiple regression analysis. Results: The main results are as follows. First, the average post-traumatic growth of the subjects was 3.01 (0-5 points). Second, the positive family relations of the subjects were 2.58 (0-5 points) and the average of spiritual sensitivity was 2.93 (1-5 points). Third, positive family relationship of cancer patients was positively correlated to post-traumatic growth, and spiritual sensitivity was verified as a moderator to positive family relationship enhancing the post -traumatic growth. Conclusion: These findings imply the importance of post-traumatic growth in cancer patients as a key intervention point to overcome pain and frustration from cancer. We suggest to develop family therapy programs and services aimed at fostering positive family relationships and meeting the needs of spiritual sensitivity for cancer patients and their families. This study also provides ways to promote post-traumatic growth in social welfare facilities in medical institutions and religious foundations.

• Journal of the Korean Society of School Health
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• v.27 no.2
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• pp.100-108
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• 2014

Purpose: The purpose of this study is to examine the effects of clinical art therapy programs utilized at schools on adolescents' suicidal thoughts and stress relief and to validate their effectiveness as a type of adolescent suicide prevention program. Methods: 12 sessions of clinical art therapy for youth suicide prevention were provided, once a week for 90 minutes, for 20 students at five middle schools in Seoul who were at high risk of committing suicide. By using the paired sample t-test, the study presented qualitative data on the analysis of pre- and post- questionnaires and on the subjects' EEG test and saliva test. Results: First, through the clinical art therapy program, the subjects' happiness index improved significantly while their scores of depression and suicidal ideation (suicidal thoughts) decreased. Second, in the EEG and saliva test conducted after the art therapy sessions, emotional stability increased and stress was reduced significantly. Third, according to the results of pre- and post- K-HTP tests and individual activities, the subjects started to recognize the seriousness of suicide and show emotional stability and positive changes in overall attitudes, valuing the rights and life of their own 'precious selves' (self respect). Conclusion: The results of this study indicate that the clinical art therapy program is significantly effective at preventing suicidal ideation by reducing suicidal impulses and depression, by increasing the happiness index, which can serve as a protective factor against suicide, and by increasing emotional stability while reducing stress. Based on the results, there is a need to develop policy measures regarding art therapy programs which can be utilized at schools.

• Structural Engineering and Mechanics
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• v.88 no.5
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• pp.451-462
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• 2023

Lumped Damage Mechanics (LDM) is a theory proposed in the late eighties, which assumes that structural collapse may be analyzed as a two-phase phenomenon. In the first (pre-localization) stage, energy dissipation is a continuous process and it may be modelled by means of the classic versions of the theory of plasticity or Continuum Damage Mechanics (CDM). The second, post-localization, phase can be modelled assuming that energy dissipation is lumped in zones of zero volume: inelastic hinges, hinge lines or localization surfaces. This paper proposes a new LDM formulation for cracking in concrete structures in tension. It also describes its numerical implementation in conventional finite element programs. The results of three numerical simulations of experimental tests reported in the literature are presented. They correspond to plain and fiber-reinforced concrete specimens. A fourth simulation describes also the experimental results of a new test using the digital image correlation technique. These numerical simulations are also compared with the ones obtained using conventional Cohesive Fracture Mechanics (CFM). It is then shown that LDM conserves the advantages of both, CDM and CFM, while overcoming their drawbacks.

• International Journal of Stem Cells
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• v.16 no.1
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• pp.117-122
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• 2023

Background and Objectives: mRNA-based protein expression technology has been used to express functional proteins. We have previously generated dopamine neurons from rat-embryo derived neural precursor cells (NPCs) through repeated transfection of synthetic transcription factor mRNA encoding dopamine-inducible genes. However, NPCs began to die approximately 10 d post-transfection. In this study, we examined a long-term transfection protocol that did not affect cell viability. Methods and Results: Experiments were performed in eight groups sorted according to the start date of mRNA transfection. mRNA was transfected into NPCs daily for 21 d and live cell images of each group were recorded. NPCs which were differentiated for more than five days showed sustained gene expression and appreciable viability despite daily mRNA transfection for 21 d. Conclusions: Repeated mRNA transfection requires cells with a sufficient differentiation period.

• Physical Therapy Rehabilitation Science
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• v.11 no.4
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• pp.391-399
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• 2022

Objective: This study aimed to investigate the effects of fall-prevention exercise programs on fall efficacy, depression and health-related quality of life in elderly. Design: a randomized controlled trial Methods: A total of 57 participants over 65-years-old have been allocated to control and experimental groups. The experimental group received 8 weeks of fall-prevention exercises that included strengthening of lower extremities, balance and gait training. They received the exercises twice a week for 50 minutes as a group.Both groups were assessed using Modified Falls Efficacy Scale (MFES), Geriatric Depression Scale (GDS), and 36-Item Short-Form Health Survey (SF-36) prior and post to the intervention. The control group also received the same exercise program after the post evaluation. Results: The experimental group showed overall improvement in MFES, GDS, and physical components of SF-36 (p<0.05). The MFES was significantly increased in the experimental group after the intervention (p<0.05). The GDS was significantly decreased in the experimental group after the intervention (p<0.05). The SF-36, only physical Function, Role limitations due to physical health, general health, and energy and fatigue categories were improved in the experimental group after the intervention (p<0.05). Conclusions: The results showed 8 weeks of fall-prevention exercise programs can increase fall efficacy and physical related quality of life while reducing depression of elderly over 65.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.31 no.1
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• pp.5-15
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• 2024

Purpose: The study aim was to examine the home healthcare system and relevant education, as well as the special certification examination, and propose a plan to increase the supply of home health nurses. Methods: A narrative literature review was conducted using data from research articles, Korean and U.S. educational institutes and organizations, Korean national statistical data, government press releases, and related medical legislation. Results: Between 2005 and 2006, 763 home health nurses were certified through the special qualification examination; however, in the 16 years from 2007 to 2023 (after the graduate-level program was established), a total of 555 home health nurses were certified, with an average of approximately 35 per year. Currently, 790 home health nurses are working at 194 medical institutions nationwide. Relatively few institutions exist in rural areas, and the supply of home health nurses is low. Only seven educational institutions offer home health nurse certification programs, with a total of 77 designated students. In contrast to Korea, post-master's certification courses are offered in the U.S.. Conclusion: To expand the supply of home health nurses, we recommend revising the rules for the special qualification examination and introducing a post-master's certification program for home health nurses. Future studies should provide additional education for applicants from other specialties in post-master's certification programs.