• 한국산업정보학회논문지
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• 제17권3호
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• pp.59-68
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• 2012

제로 클라이언트 체제는 기업의 문서 중앙화를 위해 제시된 최신의 방법이며, 이를 기업의 현실에 보다 적합하도록 토착화시키는 작업은 필수적이다. 본 연구는 제로 클라이언트 체제의 잘 알려진 보안 및 프라이버시 상의 문제점을 제외한, 사용 상의 문제점을 보완하고자 고안되었다. 즉, 작업자가 작업한 문서를 기업 클라우드 스토리지에 저장하고자 저장 카테고리를 검색하는 과정의 부담과 정확성을 향상시키기 위하여, 작업 문서의 주제어를 자동으로 파악하고, 이를 바탕으로 해당 문서가 저장되어야 하는 카테고리를 자동으로 검색하여 작업자의 확인을 통해 자동 저장되도록 하는, 지능적 아카이빙 방식을 제시한다. 본 연구에서 제시하는 주제어 자동 파악 및 자동 아카이빙을 위한 방법론과 프로토타입 시스템은 기업 환경에 적용이 가능할 정도로 정확성과 확장성을 갖추고 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1285-1292
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• 2016

Background: It is well established that mutations in the BRCA1 gene are a major risk factor for breast cancer. Induction of cancer cell death and inhibition of survival are the main principles of cancer therapy. In this context, autophagy may have dual roles in cancer, acting on the one hand as a tumor suppressor and on the other as a mechanism of cell survival that can promote the growth of established tumors. Therefore, understanding the role of autophagy in cancer treatment is critical. Moreover, defects in apoptosis, programmed cell death, may lead to increased resistance to chemotherapy. Purpose: The aim of the present study was to detect BRCA1 gene mutations in order to throw more light on their roles as risk factors for breast cancer in Egypt. Secondly the role of autophagy and apoptosis in determining response to a fluorouracil, doxorubicin, cyclophosphamide (FAC) regimen was investigated. Materials and Methods: Forty-five female breast cancer cases and thirty apparently healthy females were enrolled in the present study. Serum levels of autophagic biomarkers, Beclin 1 and LC3 as well as the serum levels of apoptosis biomarkers Bcl-2 and Caspase-3 were measured before and after chemotherapy. Results: BRCA1 mutations were found in 5 (16.7%) and 44 (99.8%) of the controls and cancer patients, the most frequent being 5382insC followed by C61G and 185 delAG. The results revealed that chemotherapy caused elevation in serum concentration levels of the autophagic biomarkers (Beclin 1 and LC3). This elevation was associated with a significant decrease in serum concentration levels of Bcl-2 and significant increase in caspase-3 concentration levels (apoptotic markers). Conclusions: The results of the present study indicate a very high level of BRCA mutations in breast cancer cases in Egypt and point to involvement of autophagic and apoptotic machinery activation in response to FAC chemotherapy.

• 산업경영시스템학회지
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• 제39권2호
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• pp.11-18
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• 2016

Product liability (PL), which began enforcement in 2002, refers to the legal responsibility of the manufacturers or sellers (wholesales or retailers) for the property damage or bodily harm caused by their product. With a strong enforcement of the Product Liability (PL) Act, companies are required to structure and operate a response system to defend or prevent product accidents efficiently, but small and medium enterprises (SMEs) are unable to respond more aggressively due to limitation of management resources. In this manner, it is important to develop response strategies for SMEs to efficiently cope with the PL Act. In this paper, the PEST (Political, Economic, Social, and Technological) analysis is performed to reveal the impact of the PL Act on SMEs in macro-economic point of view. To formulate SME's PL response strategy, SWOT analysis is performed to categorize each factors from PEST analysis and AHP is applied to identify the intensities of SWOT factors. The prioritized SWOT factor, results of PEST-SWOT-AHP analysis, are used to formulate SME's PL response strategies. The study results are briefly summarized as follows. To reduce product defects, it is necessary for SMEs to formulate PL response strategies for each phase of the product life cycle by continuously collecting and analyzing PL cases in the same industry or for similar products. In addition, SMEs should invest more technological effort to ensure product safety. Further, SMEs should spread PL awareness to all staff members by training internal PL experts. Moreover, a SME should enroll in PL insurance and spread this information to its customers so that they become aware that the company is proactively conforming to the PL law.

• Applied Microscopy
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• 제25권3호
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• pp.75-81
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• 1995

이상과 같은 실험에서 다음과 같은 사실을 요약할 수 있다. 1) ZnSSe/GaAs 에피층에는 많은 양의 적층결함과 전위 등의 결정결함이 존재하고 이들은 표면부 보다는 계면부에 더 많이 존재한다. 그러나 에피층은 기판과 pseudomorphic 성장을 이루고 있다. 2) ZnSSe/GaAs 계면에는 5nm 크기의 높이차가 나는 굴곡이 존재하며 ZnSe 버퍼 층에 관계없이 적층결함이 존재하고, 에피층 결정이 약간 기울어져서 므와레 줄무늬 패턴도 존재한다. 3) ZnSSe/GaAs 계면에는 성장 중에 S의 침투로 인한 <111>방향으로 피트가 형성되었음이 관찰되었고 이는 결함 생성 소스로 작용한다 4) 15nm 높이차가 나는 계면이 발견되었으나 기판과 정합을 이루고 있고 주변에는 적층결함도 존재하지 않는다. 그러나 미세한 므와레 줄무의형태가 존재하였다.

• 동력기계공학회지
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• 제13권5호
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• pp.52-58
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• 2009

A gas turbine consists of an upstream compressor and a downstream turbine with a combustion chamber, and also the compressor and the turbine are generally coupled using a single shaft. Many casing bolts are used to assemble two horizontally separated casings, the gas turbine casing and the compressor casing, in both of axial and vertical directions. Because drilled holes for casing bolts in vertical direction are often too close to drilled holes for casing bolts in axial direction, one can observe cracks in the area frequently during operations of a gas turbine. In this study of the root cause analysis for the cracking initiating from the drilled holes of the casings of a gas turbine, the finite element analysis(FEA) was applied to evaluate the thermal and mechanical characteristics of the casings. By applying the field operation data recorded from combined cycle power plants for FEA, thermal and thermo-mechanical characteristics of a gas turbine are analyzed. The crack is initiated at the geometrical weak point, but it is found that the maximum stress is relieved when the same type of cracks is introduced on purpose during FEA. So, it is verified that the local fracture could be delayed by machining the same type of defects near the hole for casing flange bolts of the gas turbine, where the crack is initiated.

• 전자공학회논문지SC
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• 제44권1호
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• pp.94-99
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• 2007

협심증과 급성 심근 경색증 등 관상동맥 질환이 급증함에 따라 병원 밖이나 응급실 중환자실 심도자 검사실 등에서 급성 심장 쇼크에 빠지거나 심장마비가 발생하는 경우가 많이 발생하고 있다. 이러한 심혈관 질환에는 정류성 체외생명보조장치가 널리 사용되고 있으나 이러한 장치는 그 무게와 크기로 인해 응급상황에 대처할 수 있는 능력이 작고, 막형 산화기의 전단에 인가되는 압력이 크며, 시스템 구성상 혈액이 공기에 노출된다. 박동성 혈류를 공급하기 위하여 단일 구동펌프를 이용한 시도가 있었으나 회로내의 순간 압력 상승 등으로 인한 여러 가지 단점들이 발생한다. 이러한 기존의 체외생명보조장치의 단점을 극복하고자 한국형 인공심장의 원리를 이용한 이중 박동식 혈액펌프를 개발하였다. 이 시스템의 구동원리는 막형산화기를 중심으로 전.후에 혈액펌프를 위치하여 혈액펌프를 Actuator가 한번씩 짜주는 것이다. 이런 방법으로 구동할 경우 막형산화기 후단에 있는 펌프가 음압을 동시에 일으킴으로, 막형산화기에 인가되는 큰 양압을 줄인다는 가정 하에 시스템을 개발한 것이다. 생체외 실험을 통하여 각 부분의 압력을 측정하고, 총 12건의 동물실험을 통하여 그 장점을 검증하였다

• 전기학회논문지
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• 제61권11호
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• pp.1758-1764
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• 2012

A large number of wire rope has been used in various inderstiries as Cranes and Elevators from expanding the scale of the industrial market. But now, the management of wire rope is used as manually operated by rope replacement from over time or after the accident.It is caused to major accidents as well as economic losses and personal injury. Therefore its time to need periodic fault diagnosis of wire rope or supply of real-time monitoring system. Currently, there are several methods has been reported for fault diagnosis method of the wire rope, to find out the feature point from extracting method is becoming more common compared to time wave and model-based system. This method has implemented a deterministic modeling like the observer and neural network through considering the state of the system as a deterministic signal. However, the out-put of real system has probability characteristics, and if it is used as a current method on this system, the performance will be decreased at the real time. And if the random noise is occurred from unstable measure/experiment environment in wire rope system, diagnostic criterion becomes unclear and accuracy of diagnosis becomes blurred. Thus, more sophisticated techniques are required rather than deterministic fault diagnosis algorithm. In this paper, we developed the fault diagnosis of the wire rope using probability density estimation techniques algorithm. At first, The steady-state wire rope fault signal detection is defined as the probability model through probability distribution estimate. Wire rope defects signal is detected by a hall sensor in real-time, it is estimated by proposed probability estimation algorithm. we judge whether wire rope has defection or not using the error value from comparing two probability distribution.

• Smart Structures and Systems
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• 제26권5호
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• pp.657-666
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• 2020

A rotational pulse-echo ultrasonic propagation imager that can inspect cylindrical specimens for material nondestructive evaluations is proposed herein. In this system, a laser-generated ultrasonic bulk wave is used for inspection, which enables a clear visualization of subsurface defects with a precise reproduction of the damage shape and size. The ultrasonic waves are generated by a Q-switched laser that impinges on the outer surface of the specimen walls. The generated waves travel through the walls and their echo is detected by a Laser Doppler Vibrometer (LDV) at the same point. To obtain the optimal Signal-to-Noise Ratio (SNR) of the measured signal, the LDV requires the sensed surface to be at a right angle to the laser beam and at a predefined constant standoff distance from the laser head. For flat specimens, these constraints can be easily satisfied by performing a raster scan using a dual-axis linear stage. However, this arrangement cannot be used for cylindrical specimens owing to their curved nature. To inspect the cylindrical specimens, a circular scan technology is newly proposed for pulse-echo laser ultrasound. A rotational stage is coupled with a single-axis linear stage to inspect the desired area of the specimen. This system arrangement ensures that the standoff distance and beam incidence angle are maintained while the cylindrical specimen is being inspected. This enables the inspection of a curved specimen while maintaining the optimal SNR. The measurement result is displayed in parallel with the on-going inspection. The inspection data used in scanning are mapped from rotational coordinates to linear coordinates for visualization and post-processing of results. A graphical user interface software is implemented in C++ using a QT framework and controls all the individual blocks of the system and implements the necessary image processing, scan calculations, data acquisition, signal processing and result visualization.

• 무역상무연구
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• 제12권
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• pp.133-162
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• 1999

The international sale transaction is in essence a sale of goods and presents all those commercial and legal problems in any sale of goods. As a result, A International sales contract imposes several duties on the parties : the seller must deliver the goods and transfer ownership in them, while the buyer must pay the price and take delivery of the goods. However, there are several problems which impede a active transaction between seller and buyer who have their places of business in other countries each other. Therefore, It is necessary to provide the concept on the conformity of goods in the Int'l Sale of Goods. Especially, In our consideration for the point of time when defects occurs, the existence of non-conformity of goods should be judged on the basis of time of delivery rather than time of contract. Moreover, The burden of proof about nonconformity of goods is another fact which make an international dispute between the contractual parties in an international trade. Thus, The consistency in the interpretation of law must be maintained betweened the warranty and seller's liability. In the Uniform Commercial Code and UN Convention, non-conformity of contract is made of contract liability. And in our civil and commercial law provisions of warranty should be understand as the special ones of the provisions of general non-performance of obligation liability. As a result, More concrete study of them is required because they may have a great influence especially on international trade. As a result, We should be our best in finding a helpful and systematic structure that the dualistic structure of nonperformance of obligation liability and warranty liability must be unified by studying the theories of English and American warranty and our legal system, as well as international practice and usage being used in an international trade.

• Archives of Plastic Surgery
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• 제43권4호
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• pp.339-343
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• 2016

Background Numerous techniques have been used to achieve long-term projection of the nipple following nipple-areola reconstruction. However, the reconstructed nipple loses projection over time. We describe a technique that uses local flaps to improve the lost projection of reconstructed nipples. Methods Between November 2013 and March 2015, nine patients (11 nipples) underwent revisional nipple reconstruction for lost projection. Only C-H nipple reconstructions were included in this study. The medical history of each patient was reviewed and photographs were taken in front and lateral views. All patients attended routine follow-up visits. Deepithelialized triangular flaps were made on all four sides of the nipple and buried in the opposite corners in order to augment the volume of the nipple. Anchoring sutures were used to attach each triangular flap on the side opposite their point of origin, and the resulting defects were closed directly. Results This procedure was used successfully in nine patients (11 nipples). Adequate projection was achieved in all patients and no complications occurred. The average nipple height was 3 mm before operation, 7 mm one day after operation, 5 mm at the six-month follow-up, and 5 mm at the 12-month follow-up. The average nipple-areolar angle was $164^{\circ}$ before the operation, $111^{\circ}$ one day after the operation, $130^{\circ}$ at the six-month follow-up, and $133^{\circ}$ at the 12-month follow-up. Conclusions The method described provides a solution to the loss of projection in reconstructed nipples. We recommend this technique because it leads to better projection, greater volume, and a more natural shape.