• Proceedings of the KIEE Conference
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• 1993.07a
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• pp.391-394
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• 1993

The acceleration/deceleration control method and interpolated operating are essential to the servo motor control system. In a few years ago, a floating point DSP chip was used for the purpose of processing a lot of calculated amount. But in this paper, we proposed new acceleration/deceleration control method and circular interpolation algorithm without another floating point DSP chip. The validity of proposed algorithms are verified through computer simulation and experimental result.

• International Journal of Oral Biology
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• v.34 no.4
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• pp.215-222
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• 2009

Medial vestibular nucleus (MVN) neurons are involved in the reflex control of the head and eyes, and in the recovery of vestibular function after the formation of peripheral vestibular lesions. In our present study, whole cell patch clamp recordings were carried out on MVN neurons in brainstem slices from neonatal rats to investigate the actions of a group I metabotropic glutamate receptor (mGluR) agonist upon synaptic transmission and ionic currents. Application of the mGluR I agonist (S)-3,5- dihydroxyphenylglycine (DHPG) increased the frequency of miniature inhibitory postsynaptic currents (mIPSCs) but had no effect upon amplitude distributions. To then identify which of mGluR subtypes is responsible for the actions of DHPG in the MVN, we employed two novel subtype selective antagonists. (S)-(+)-$\alpha$-amino-a-methylbenzeneacetic acid (LY367385) is a potent competitive antagonist that is selective for mGluR1, whereas 2-methyl-6-(phenylethynyl)-pyridine (MPEP) is a potent noncompetitive antagonist of mGluR5. Both LY367385 and MPEP antagonized the DHPG-induced increase of mIPSCs, with the former being more potent. DHPG was also found to induce an inward current, which can be enhanced under depolarized conditions. This DHPG-induced current was reduced by both LY367385 and MPEP. The DHPG-induced inward current was also suppressed by the PLC blocker U-73122, the $IP_3$ receptor antagonist 2-APB, and following the depletion of the intracellular $Ca^{2+}$ pool by thapsigargin. These data suggest that the DHPG-induced inward current may be mainly regulated by the intracellular $Ca^{2+}$ store via the PLC-$IP_3$ pathway. In conclusion, mGluR I, via pre- and postsynaptic actions, may modulate the excitability of the MVN neurons.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.3
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• pp.211-215
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• 2009

As Programmable Logic Controllers (PLCs) are increasingly used to implement safety critical systems such as nuclear instrumentation & control system, formal verification for PLC based programs is becoming essential. This paper proposes a formal verification technique for PLC program implemented with function block diagram (FBD). In order to verify an FBD program, we translate an FBD program into a Verilog model and perform model checking using SMV model checker We developed a tool, FBD Verifier, which translates FBD programs into Verilog models automatically and supports efficient and intuitive visual analysis of a counterexample. With the proposed approach and the tool, we verified large FBD programs implementing reactor protection system of Korea Nuclear Instrumentation and Control System R&D Center (KNICS) successfully.

• Tuberculosis and Respiratory Diseases
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• v.49 no.3
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• pp.310-322
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• 2000

Background : Phospholipase C(PLC) plays an important role in cellular signal transduction and is thought to be critical in cellular growth, differentiation and transformation of certain malignancies. Two second messengers produced from the enzymatic action of PLC are diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3). These two second messengers are important in down stream signal activation of protein kinase C and intracellular calcium elevation. In addition, functional domains of the PLC isozymes, such as Src homology 2 (SH2) domain, Src homology 3 (SH3) domain, and pleckstrin homology (PH) domain play crucial roles in protein translocation, lipid membrane modificailon and intracellular memrane trafficking which occur during various mitogenic processes. We have previously reported the presence of PLC-${\gamma}1$, ${\gamma}2$, ${\beta}1$, ${\beta}3$, and ${\delta}1$ isozymes in normal human lung tissue and tyrosine-kinase-independent activation of phospholipase C-${\gamma}$ isozymes by tau protein and AHNAK. We had also found that the expression of AHNAK protein was markedly increased in various mstologic types of lung can∞r tissues as compared to the normallungs. However, the report concerning expression of various PLC isozymes in lung canærs and other lung diseases is lacking. Therefore, in this study we examined the expression of PLC isozymes in the paired surgical specimens taken from lung cancer patients. Methods : Surgically resected lung cancer tissue samples taken from thirty seven patients and their paired normal control lungs from the same patients, The expression of various PLC isozymes were studied. Western blot analysis of the tissue extracts for the PLC isozymes and immunohistochemistry was performed on typical samples for localization of the isozyme. Results : In 16 of 18 squamous cell carcinomas, the expression of PLC-${\gamma}1$ was increased. PLC-${\gamma}1$ was also found to be increased in all of 15 adenocarcinoma patients. In most of the non-small cell lung cancer tissues we had examined, expression of PLC-${\delta}1$ was decreased. However, the expression of PLC-${\delta}1$ was markedly increased in 3 adenocarcinomas and 3 squamous carcinomas. Although the numbers were small, in all 4 cases of small cell lung cancer tissues, the expression of PLC-${\delta}1$ was nearly absent. Conclusion : We found increased expression of PLC-${\gamma}1$ isozyme in lung cancer tissues. Results of this study, taken together with our earlier findings of AHNAK protein-a putative PLD-${\gamma}$, activator-over-expression, and the changes observed in PLC-${\delta}1$ in primary human lung cancers may provide a possible insight into the derranged calcium-inositol signaling pathways leading to the lung malignancies.

• Proceedings of the Korean Fiber Society Conference
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• 1991.06b
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• pp.18-18
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• 1991

• Proceedings of the KIEE Conference
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• 2001.11c
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• pp.327-330
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• 2001

본 논문에서는 위험요소를 내재하고 있는 로켓시스템에 대해 원거리에서 실시간 모니터링 및 제어를 할 수 있도록 원격 제어시스템을 설계, 개발하였다. 뿐만 아니라 로켓 근처에 위치한 무인 시설물 내에는 원격제어에 따른 로켓내부 시스템의 각종 센서 출력값을 멀티채널방식을 이용하여 장시간에 걸쳐 저장하고 원격지에 위치한 유인 시설물 내에서 LAN 통신을 통해 데이터를 분석할 수 있도록 DAS(Data Acquisition System)을 설계하고 개발하였다. 개발된 시스템은 간이 연계시험을 통해 입증하였으며, 향후 3단형 과학로켓발사통제시스템에 적용할 예정이다.

• Korean Journal of Pharmacognosy
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• v.30 no.3
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• pp.280-283
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• 1999

Using the bioassay-guided fractionation and isolation technique, two $PLC{\gamma}1$ inhibitors were isolated from the sarcotestas of Ginkgo biloba (Ginkgoaceae). The structures of these compounds were identified as (3R)-(-)-8-hydroxy-3-(6'-pentadecenyl)3,4-dihydroisocoumarin (1) and 3-heptadecen-2-one (2) by UV, IR, MS, $^1H-NMR$, $^{13}C-NMR$ and $^1H-^{13}C\;COSY$. Isolate compounds 1 and 2 have not been reported previously from the sarcotestas of G. biloba and Ginkgoaceae, respectively. In addtion, these compounds showed significant $PLC{\gamma}1$ inhibitory effects with the $IC_{50}$ of the 9.7 (1) and $25.6\;{\mu}M\;(2)$.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.33 no.4
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• pp.331-335
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• 2020

In this study, through the accumulated technologies such as real-time monitoring of power consumption using power line communication (PLC) method, power control, and automatic blocking of standby power, to commercialize them, we developed the hardware design, algorithm, protocol and module along with data transmission using PLC. We conducted the study to develop advanced products. We also proposed cloud-based smart outlet products with a novel type of outlet. These products can measure the internal power consumption through the H/W modules and the modules that control the power of household appliances connected to the smart outlets and smart plugs. Subsequently, they transmit the measurements to the energy saving system server via a communication module. This system can control the terminal device connected to the Gateway (G/W) server through a mobile phone. This will allow the customer to check the power consumption of the building at any given time, to turn the terminal on/off, and to maximize the energy efficiency during the construction of new apartments or multi-family housing in an area.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.2
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• pp.354-359
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• 2016

Power plants maintenance data is to be sent to management server system via a communication network. In this case, reliable communication network is required. Transmission of the power plants maintenance data is used in the wired communication network or wireless communication network. PLC communication network is a kind of wired communication network. However PLC communication network is easily affected by noise. On the vulnerable areas in power line system, such as a mountain or rural areas, it is difficult to form a power line communication network. For a wireless communication, environment are also influenced factors in wireless communication. Harsh environmental factors are bring the communication characteristic degradation. In such areas it can be used a combination of two networks and in this way the complementary function can be achieved. Power plants are distributed in various regions across the country. The appropriate communication network is needed to maintain the power plant.This study investigated the effect of environment on the wired communication and wireless communication. It would examine a variable factor which is affect to the communication characteristic. We used PLC communication for wired communication network and ZigBee communication for wireless communication network. We investigated the characteristics of a single communication network and it raised the need for a complex communication technology to complement a single communication network.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2007.06a
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• pp.425-426
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• 2007