The object of this study is to evaluate the possibility of chemical-induced liver disorder among workers exposed to various chemicals and to classify the the liver function abnormalities by causes and to analyse the risk factors for each liver disorders. A cross-sectional study including questionnaire survey, physical examination, laboratory tests and ultrasonography of liver was conducted on 1,126 workers, 459 workers in a coal chemical plant(company A) and 667 workers in an insulation material manufacturing factory(company B). An industrial hygienist reviewed the chemicals used in both companies and evaluated the work environments to classify the workers by chemical exposure semiquantitatively. The results are as follows: 1. Of 459 workers in company A, 83 workers(18.1%) are classified as nonexposed, group 163(35,5%) as short-term exposure group, 155(33.8%) as intermediately exposed group and 58(12.6%) as long-term exposed group bared on the mean daily exposure to hepatotoxic chemicals evaluated by an industrial hygienist. Of 667 workers in company B, 484(72.6%) workers were classified as nonexposed and 183(35.5%) as exposed group. 2. Workers with SGOT level higher than 40 IU/l were (10.0%) in company A and 77(11.5%) in company 3, and those with SGPT level higher than 35 IU/l were 118(25.7%) in company A and 198(29.7%) in company B. The differences were not significant between companies and between exposure groups(p>0.05). Workers with $\gamma-GT$ level higher than 62 IU/l were 29(6.3%) in company A and 77(11.5%) in company B (p<0.01). The difference between exposure groups was not significant(p>0.05) within companies. Workers with liver function abnormalities(defined as SGOT higher than 40 IU/l or SGPT higher than 35 IU/l) were 338(30.0%) among 1,126 workers. Of 338 workers with live. function abnormalities 139(12.3%) had fatty liver by ultrasonography, 79(7.0%) had alcoholic liver(defined as workers with liver function abnormalities with weekly alcohol consumption greater than 280 g for more than 5 years), 54(4.8%) had hepatitis B, 12(1.1%) had hepatitis C and the other 114(33.7%) was not otherwise classified. Prevalences of alcoholic liver and fatty liver were significantly lower in company A(prevalence ratio 0.24 for alcoholic liver, p<0.001, prevalence ratio 0.76 for fatty liver, p<0.05) but prevalences of liver disorders between exposure groups within companies were not significant(p>0.05). 3. Summary prevalence ratios(SPR) of live. function abnormalities, fatty live. and other liver disorders, adjusted by age and company were not significantly higher in exposed group in any chemicals(p>0.05) but in some chemicals, SPRs were significantly lower. 4. On simple analysis of risk factors for liver function abnormalities, prevalence odds ratio(POR) of those with age between 30 and 39 was 1.54(p<0.01) and those with age ever 40 was 1.51(p<0.01). POR of those with histories of liver disorders and general anesthesia was 1.77(p<0.001) and 4.02 for those with overweight and 6.23 for those with obesity, defined by body mass index(p<0.001). 5. On logistic regression analysis, risk factors of liver function abnormality were fatty liver(POR 2.92 for grade 1, 12.15 for grade 2), presence of hepatitis B surface antigen(POR 3.62) and obesity(POR 5.38 for overweight and 16.52 for obesity). Presence of hepatitis B surface antigen(POR 0.18) was the only preventive facto. of fatty live. Company(POR 0.30) and obesity(POR 2.49 for overweight, 4.52 for obesity) were related to the alcoholic live. Obesity(POR 2.94 for overweight) was the only significant risk factor of hepatitis B and there was no significant risk factor for liver function abnormality not otherwise classified. It is concluded that the evidence of liver disorder related with chemical exposure is not evident in these factories. It is also postulated that fatty liver and alcoholic liver is most common causes of liver function abnormalities among workers and effort for weight control and improvement of life style should be done.
Journal of Korean Society of Environmental Engineers
/
v.30
no.9
/
pp.961-972
/
2008
In 2004, total emissions of Greenhouse Gases(GHGs) in Korea was estimated to be about 590 million metric tons, which is the world's 10th largest emissions. Considering the much amount of nation's GHG emissions and growing nation's position in the world, GHG emissions in Korea should be reduced in near future. The CO$_2$ emissions from two sub-sections of energy sector in Korea, such as thermal power plant and industry section(including manufacturing and construction industries), was about 300 million metric tons in 2004 and this is 53.3% of total GHG emissions in Korea. So, the mitigation of CO$_2$ emissions in these two section is more important and more effective to reduce the nation's total GHGs than any other fields. In addition, these two section have high potential to qualitatively and effectively apply the CCS(Carbon Capture and Storage) technologies due to the nature of their process. There are several CCS technologies applied to these two section. In short term, the chemical absorption technology using amine as a absorbent could be the most effectively used. In middle or long term, pre-combustion technology equipped with ATR(Autothermal reforming), or MSR-$H_2$(Methane steam reformer with hydrogen separation membrane reactor) unit and oxyfuel combustion such as SOFC+GT(Solid oxide fuel cell-Gas turbine) process would be the promising technologies to reduce the CO$_2$ emissions in two areas. It is expected that these advanced CCS technologies can reduce the CO$_2$ avoidance cost to $US 8.5-43.5/tCO$_2$. Using the CCS technologies, if the CO$_2$ emissions from two sub-sections of energy sector could be reduced to even 10% of total emissions, the amount of 30 million metric tons of CO$_2$ could be mitigated.
Journal of Korean Society of Environmental Engineers
/
v.36
no.7
/
pp.514-520
/
2014
In this study, the production potential of alternative coagulant ($Al_2(SO_4)_3$ solution) having the identical coagulation activity with respect to the commercial coagulant was investigated. The raw material of alternative coagulant was a spent catalyst including aluminium (waste activated alumina) generated in the manufacturing process of the polymer. The alternative coagulant was produced through a series of processes: 1) intense heat and grinding, 2) chemical polymerization and substitution with $H_2SO_4$ solution, 3) dissolution and dilution and 4) settling and separation. To determine the optimal operating conditions in the lab-scale autoclave and dissolver, the content of $Al_2O_3$ in alternative coagulant was analyzed according to changes of the purity of sulfuric acid, reaction temperature, injection ratio of sulfuric acid and water in the dissolver. The results showed that the alternative coagulant having the $Al_2O_3$ content of 7~8% was produced under the optimal conditions such as $H_2SO_4$ purity of 50%, reaction temperature of $120^{\circ}C$, injection ratio of $H_2SO_4$ of 5 times and injection ratio of water of 2.3 times in dissolver. In order to evaluate the coagulation activity of the alternative coagulant, the Jar-test was conducted to the effluent in aerobic reactor. As a result, in both cases of Al/P mole of 1.5 and 2.0, the coagulation activity of the alternative coagulant was higher than that of the existing commercial coagulant. When the production costs were compared between the alternative and commercial coagulant through economic analysis, the production cost reduction of about 50% was available in the case of the alternative coagulant. In addition, it was identified that the alternative coagulant could be applied at field wastewater treatment plant without environmental problem through ecological toxicity testing.
Jo, Hye Jin;Choi, Beom Geun;Wu, Yan;Moon, Jin San;Kim, Young Jo;Yoon, Ki Sun
Journal of Food Hygiene and Safety
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v.30
no.2
/
pp.178-188
/
2015
Microbial quality of baked egg products was evaluated by counting the levels of sanitary indicative bacteria (aerobic plate counts, coliforms, and E. coli), L. monocytogenes and Salmonella spp. at the critical control points (CCPs) of manufacturing process. In addition, the survival and growth of foodborne pathogens in various egg products (cheese, tuna, tteokgalbi, pizza omelets, baked egg, and steamed egg) were investigated at 4, 10, and $15^{\circ}C$. The contamination level of aerobic plate counts decreased from 4.67 log CFU/g at CCP 1 to 0.56 log CFU/g at CCP 3 in baked egg products. No coliforms and E. coli were detected at all CCPs. Although L. innocua and Salmonella spp. were identified at CCP 1, no L. monocytogenes and Salmonella spp. were detected in the final products. The contamination levels of aerobic plate counts and coliforms in egg strips and number of aerobic plate counts in Tteokgalbi omelet are higher than the microbiological standard of processed egg products. At $10^{\circ}C$, the growth of all pathogens was not prevented in omelet and baked egg, but the populations of S. Typhimurium and E. coli were reduced in steamed egg at $10^{\circ}C$, regardless of the presence of other pathogens. The growth of L. monocytogenes was faster than that of S. Typhimurium and E. coli in omelet. More rapid growth of S. Enteritidis than S. Typhimurium was observed in egg products, indicating the greater risk of S. Enteritidis than S. Typhimurium in egg products.
Journal of the Korean Society of Food Science and Nutrition
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v.13
no.3
/
pp.319-325
/
1984
This experiment aims to observe the nutritive value of blood sausages by manufacturing three kinds of them in order to utilize various by-products of swine when it is processed. In attempt to do so, five different diets were made: one control diet and four diets in which three kinds of blood sausages(blood sausage-1 was made with sausage meat 10%, fat 40%, blood 20%, skin 20% and liver 2%. blood sausage-2 was made with ham meat 30%, fat 20%, blood 20%, liver 2% and skin 20%. blood sausage-3 was made with smoked ham patch 30%, fat 20%, blood 20%, liver 2% and skin 20%) and mixed sausage(sausage meat 20%, fat 10% and fish meat 35%) were mixed with control diet at the rates of 10% respectively. These diets were fed to growing male and female albino rats for 6 weeks. The results obtained through this study are summarized as follows. In body weight gain of male rats, blood sausage-1 and 2 groups were significantly higher than mixed sausage group during the experimental period, and in that of female rats, control group and blood sausage-1 group were similar, but the other groups were lower than control group. Food intake was different in each group every week, but the amount of that was similar to each one throughout all experimental period. Food efficiency ratio and protein efficiency ratio in male were similar in each group, but slightly different in female during the feeding period. Liver weights of male in mixed sausage group and blood sausage-3 group were lower than those in control group and blood sausage-2 group, but liver weight of female in blood sausage-2 group was lower than that in control group. And all groups were similar in liver weight per 100 g of body weight. Mixed sausage group and blood sausage-1 group were lower than control group in kidney weight of male, and blood sausage-1 group was lower than control group in kidney weight of female. Kidney weight per 100 g of body weight of male showed that blood sausage-1 group was lower than the other groups. Spleen weight was similar in all groups. Hematocrit and hemoglobin contents in blood, total protein, albumin, albumin/globulin ratio, total lipid and total cholesterol contents in serum were showed almost similar in all groups.
As National Pension Scheme for all nation complete in 1999 through expanding application in cities, the public pension including Public Occupational Pension became main axis of old-age income maintenance. After 4years since then, now, it is only half of total National Pension insured persons who have been qualified to receive pension through participate and contribution. The other half of National Pension insured is left the excluded from public pension. This paper is intended to identify scale and characteristics of the excluded from public pension and to analysis its cause, and to explore policy measures for solving the excluded's problem. for current recipients over 60 years old generation, the its excluded's scale is no less than 86% of the old over 60 years. The probability of getting in the excluded is high in case of old elderly and female for current elderly generation. For future recipients 18-59 years working generation, the its excluded's scale is no less than 61% of the 18-59 years total population. The probability of getting in the excluded is high in case of 18-29 years and female for current working generation. As logistic regression analysis determinant factor of paying or not pension contribution for future recipients, it appear that probability of getting in the excluded for current working generation is high in case of younger old, lower education attainment, irregular employee, working at agriculture forestry fishery sector, construction sector, wholesale retail trade restaurants hotels sector, financial institution and insurance real estate renting and leasing sector in comparison with manufacturing sector, occpaying at elementary occupation, professionals technicians and associate professionals, sale and service workers, plant machine operators and assemblers, legislators senior officials and managers in comparison with clerks. The Policy measures for the current recipient old generation have need to reinforce supplemental role of Senior's pension(non-contribution pension) until maturing of public pension, because of no having chance of public pension participants for them. And the Policy measures for the future recipient working generation have need to restructure social security fundamentally corresponding with social-economic change as labour market and family structure etc. The pension system has need to change from one earner one pension to one citizen one pension with citizenship rights. At this point, public pension have need to manage with combining insurance's contribution principle and citizenship principle financing by taxes. Then public pension will become substantially universal social network for old-age income maintenance and we can find real solution for the excluded from.
Xie, Li Rui;Jun, Do Youn;Park, Ju Eun;Kwon, Gi Hyun;Cho, Bonggeun;Park, Hyun Woo;Lee, Chang Woo;Kim, Chang Young;Jung, Hyo-Il;Kim, Young Ho
Journal of Life Science
/
v.26
no.8
/
pp.936-942
/
2016
As the incidence of environmental diseases is increasing due to harmful environmental factors, there is a rising interest in developing eco-friendly materials for housing. In this study, we sought to develop antimicrobial interior fabric blind materials by employing ethanol extract of a medicinal plant Zanthoxylum piperitum DC. As determined by the disc diffusion method, the zones of inhibition of the pericarp ethanol extract at a concentration of 5 mg/disc against Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus mutans were 13.5±1.5 mm, 14.0±0.5 mm and 15.0±0.1 mm, respectively, whereas the leaf ethanol extract (5 mg/disc) against K. pneumoniae, S. aureus, and S. mutans were 12.8± 0.3 mm, 13.5±1.0 mm, and 12.0±0.1 mm, respectively. The IC50 of the leaf ethanol extract against K. pneumoniae, S. aureus and S. mutans were about 0.5 mg/ml, 0.1 mg/ml and 1.0 mg/ml respectively. To examine whether the leaf ethanol extract possessing antibacterial activity of Z. piperitum DC can be applicable to production of antimicrobial fabric blind materials, the fabrics treated with either 1.0% or 2.0% of the leaf ethanol extract were tested for antibacterial activity against K. pneumoniae and S. aureus using International Standard Fabrics Test Method. The results indicate that the fabric treated with the ethanol extract of Z. piperitum DC possesses an excellent antimicrobial activity against both pathogenic bacteria. These results suggest that Z. piperitum DC may be applicable to producing functional fabrics which are effective in reducing the harmful bacterial factors in indoor environments.
Green tea, a leaf of the plant Camellia sinensis, is one of the most consumed traditional oriental beverages. Green tea has been considered a medicine and a healthful beverage since ancient times, but recently it has received a great deal of attention because of its antioxidants like polyphenols. Moreover, green tea contains amino acids, carbohydrates, proteins, chlorophyll, volatile compounds, minerals, and phytochemical components that are essential or helpful to human health. Depending on the manufacturing process, green teas are classified into several types. Among these, powdered green tea can be effective in the absorption of ingredients compare with other types of green tea since we take the beverage with powder itself. In this paper, the contents of general ingredients (moisture, proteins, fat, carbohydrates, and ash), minerals (Fe, Mg, Ca, Na, K, and P), hunter color values, and alcohol insoluble substance were determined in total of six powdered green teas commercialized in Korea and Japan.
Shin Young Park;Ki Yun Kim;Do Youn Jun;Sung Chul Kim;Hyo-Il Jung;Young Ho Kim
Journal of Life Science
/
v.33
no.10
/
pp.820-827
/
2023
Since COVID-19 began at the end of 2019, the wearing time of protective clothing used to prevent pathogenic bacteria and virus infection has increased, and the development of safe protective materials that are human-friendly and have antibacterial and antiviral functions has been required. In this study, we investigated the possibility of developing natural antibacterial protection materials using ethanol extract of the medicinal plant Zanthoxylum Piperitum DC. The antibacterial activity assay of the 80% ethanol extract of Z. piperitum DC leaves against various nosocomial infectious bacteria, using the disk diffusion method, showed that Staphylococcus aureus ATCC 25923, Klebsiella pneumoniae ATCC 13883, Salmonella typhimurium, and Aeromonas hydrophila are sensitive to the inhibitory action of the extract. The IC50 values of the ethanol extract against S. aureus, K. pneumoniae, P. vulgaris and A. hydrophila were about 0.59 mg/ml, 0.50 mg/ml, 1.06 mg/ml, and 0.06 mg/ml, respectively. To determine whether the ethanol extract of Z. piperitum DC leaves can be applied to the development of antibacterial protective fabric, the ethanol extract was tested using a protective fabric from the KM Health Care Corp. using the JIS L1902-Absorption method. As a result, the bacteriostatic and bactericidal activity values of S. aureus ATCC 25923 and K. pneumoniae ATCC 13883 appeared to be more than 2.0 when treated with the ethanol extract at a concentration of 1% (w/v). Together, these results suggest that Z. piperitum DC leaves can be applied to develop natural antibacterial functional protective fabrics.
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