• International conference on construction engineering and project management
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• 2009.05a
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• pp.1000-1014
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• 2009

Research sponsored by the Korean Government investigated the establishment of a risk management process by Korean contractors involved with plant projects in the Middle East. This research effort builds upon the work completed by the Construction Industry Institute (CII), called the International Project Risk Assessment (IPRA) tool and method, and also explored how CII's Project Definition Rating Index (PDRI) could be incorporated to improve project planning by addressing risks and scope development issues. Specific findings and recommendations were developed including the creation of the Contractor Critical Areas of Concern (CCAC) risk screening tool for Korean contractors pursuing Middle East oil and gas projects.

• Molecules and Cells
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• v.25 no.4
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• pp.494-503
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• 2008

Many therapeutic glycoproteins have been successfully generated in plants. Plants have advantages regarding practical and economic concerns, and safety of protein production over other existing systems. However, plants are not ideal expression systems for the production of biopharmaceutical proteins, due to the fact that they are incapable of the authentic human N-glycosylation process. The majority of therapeutic proteins are glycoproteins which harbor N-glycans, which are often essential for their stability, folding, and biological activity. Thus, several glyco-engineering strategies have emerged for the tailor-making of N-glycosylation in plants, including glycoprotein subcellular targeting, the inhibition of plant specific glycosyltranferases, or the addition of human specific glycosyltransferases. This article focuses on plant N-glycosylation structure, glycosylation variation in plant cell, plant expression system of glycoproteins, and impact of glycosylation on immunological function. Furthermore, plant glyco-engineering techniques currently being developed to overcome the limitations of plant expression systems in the production of therapeutic glycoproteins will be discussed in this review.

• Journal of the Korea Safety Management & Science
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• v.13 no.4
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• pp.61-69
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• 2011

The hazard conditions on plant works of the steel industry have been investigated to efficiently prevent from industrial accidents. The plant works are eventually carried out by workers of smaller service companies where the safety management systems are not well established, on behalf of the main steel company. Based on the preliminary risk assessment on the plant working and open literature reviews, the safety management systems, which can be applied to the plant workplace of each process, are studied and then the step-by-step 4M check-list method is established. Accordingly, the risk assessment technique using 4M checklist for the plant workplace is proposed. In addition, a standardized flow-chart for safety management of plant work is introduced. These risk assessment technique and flow-chart can definitely contribute to the reduction of industrial accidents, considering the risk characterization and the unsafe conditions in small and medium-sized plant workplace, as effective safety management tools and safety guide line.

• Journal of Microbiology and Biotechnology
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• v.34 no.5
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• pp.1003-1016
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• 2024

This study explores the potential of plant-based decellularization in regenerative medicine, a pivotal development in tissue engineering focusing on scaffold development, modification, and vascularization. Plant decellularization involves removing cellular components from plant structures, offering an eco-friendly and cost-effective alternative to traditional scaffold materials. The use of plant-derived polymers is critical, presenting both benefits and challenges, notably in mechanical properties. Integration of plant vascular networks represents a significant bioengineering breakthrough, aligning with natural design principles. The paper provides an in-depth analysis of development protocols, scaffold fabrication considerations, and illustrative case studies showcasing plant-based decellularization applications. This technique is transformative, offering sustainable scaffold design solutions with readily available plant materials capable of forming perfusable structures. Ongoing research aims to refine protocols, assess long-term implications, and adapt the process for clinical use, indicating a path toward widespread adoption. Plant-based decellularization holds promise for regenerative medicine, bridging biological sciences with engineering through eco-friendly approaches. Future perspectives include protocol optimization, understanding long-term impacts, clinical scalability, addressing mechanical limitations, fostering collaboration, exploring new research areas, and enhancing education. Collectively, these efforts envision a regenerative future where nature and scientific innovation converge to create sustainable solutions, offering hope for generations to come.

• 한국가스학회:학술대회논문집
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• 2005.10a
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• pp.141-145
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• 2005

DME (Di-Methyl Ether) is a new clean fuel and an environmental-friendly energy resource, also is recently increasing with an alternative interest because of the industrial use. DME has been shown to have excellent properties as a diesel fuel giving emission level better than ULEV standard. So it has been attracting considerable as an alternative diesel fuel. In this study, we carried out simulation of separation and purification process of demo plant for 101on per day DME production, which cause the effect that is important in productivity, from operation results of pilot plant for 50kg per day DME production. The liquefied stream, which was separated by gas-liquid separator after DME reactor, includes $CO_2$, DME, Methanol and $H_2O$. We established three distillation columns for separation and purification of the stream. $CO_2$ was extracted from the stream by first distillation column, DME was extracted by second column and Methanol was extracted by third column. We investigated and analyzed the effect which the actual operation variables cause in efficiency of process and optimized process, finally we got the DME of purity $100\%$.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.63 no.4
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• pp.290-294
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• 2014

PID(Proportional, Integral, Derivative) controller is the most popular process controllers in nuclear power plants. The optimized parameter setting of the process controller contributes to the stable operation and the efficiency of the operating nuclear power plants. PID parameter setting is tuned when new process control systems are installed or current process control systems are changed. When the nuclear plant is shut down, a lot of PID tuning methods such as the Trial and Error method, Ultimate Oscillation method operation, Ziegler-Nichols method, frequency method are used to tune the PID values. But inadequate PID parameter setting can be the cause of the unstable process of the operating nuclear power plant. Therefore the results of PID parameter setting should be simulated, optimized and finally verified. This paper introduces the simulation method of PID tuning to optimize the PID parameter setting and confirms them of the actual PID controller in the operating nuclear power plants. The simulation method provides the accurate process modeling and optimized PID parameter setting of the multi-loop control process in particular.

• Korean Journal of Computational Design and Engineering
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• v.15 no.5
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• pp.343-353
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• 2010

Time to market and cost-efficient production are some of the challenge that manufacturing industries face. Modern methods of engineering can't help such organizations attain competitive advantage. To help these situations, MEMPHIS (Middleware for Exchanging Machinery and Product Data in Highly Immersive Systems) was introduced as an approach that enables VE (Virtual Engineering) and links engineering applications with VR (Virtual Reality) solutions. Thus an environment is provided to implement virtual design reviews and enable the application of virtual prototyping methods. However MEMPHIS could just handle Product data for virtual design review and simulation. In this paper, we newly define and develop the extended MEMPHIS that enables virtual manufacturing with Process, Resource and Plant data as well as Product data.

• Clean Technology
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• v.19 no.2
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• pp.156-164
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• 2013

In this study, we analyzed the operational characteristics of a 0.25 MW methanation pilot plant. Isothermal reactor controled the heat released from methanation reaction by saturated water in shell side. Methanation process consisting of isothermal reactor and adiabatic reactor had advantages with no recycle compressor and more less reactors compared with methanation process with only adiabatic reactors. In case that $H_2$/CO ratio of syngas was under 3, carbon deposition occurred on catalyst in tube side of isothermal reactor and the pressure of reactors increased. In case that $H_2$/CO ratio was maintained around 3, no carbon deposition on catalyst in tube side of isothermal reactor was found by monitoring the differential pressure of reactors and by measuring the differential pressure of several of tubes filled with catalyst before and after operating. It was shown that CO conversion and $CH_4$selectivity were over 99, 97%, respectively, and the maximum $CH_4$productivity was $695ml/h{\cdot}g-cat$.

• Plant Journal
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• v.7 no.3
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• pp.65-73
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• 2011

This research has suggested a method to select pipe wall thickness by application of the value engineering to reduce the cost and quantity that are major part of construction materials. This research shows that the application of value engineering reduces the cost of piping materials by optimizing pipe wall thickness while maintaining process flow date of design pressure and design temperature. Based on this knowledge, the application of the value engineering will lead to the cost reduction and quantity reduction by effective selection of pipe wall thickness. The application of the value engineering will help the EPC companies to win a contract in the overseas plant market.

• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.4
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• pp.325-331
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• 2006

Various environmental conditions affecting total phosphorus removal from farm wastewater in a biofilm filter process were investigated using loess balls and Chromobacterium LEE-38 at a pilot plant. When Chromobacterium LEE-38 was used, the removal efficiency of total phosphorous was approximately 10- or 5-fold higher than that of Acinetobacter CHA-2-14 or Acinetobacter CHA-4-5, respectively. When a loess ball of $11{\sim}14mm$ manufactured at a $960^{\circ}C$ calcining temperature was used, the removal efficiency of total phosphorous was 90.0%. When 70% of the volume fraction was used, the maximum efficiency of total phosphorus removal was 93.1%. Notably, when the initial pH was in the range of 6.0 to 8.0, the maximum removal efficiency of total phosphorus was obtained after 30 days. When the operating temperature was in the range of 30 to $55^{\circ}C$, the maximum removal efficiencies of total phosphorus, 95.6 to 94.6%, were obtained. On the other hand, at operating temperatures below $20^{\circ}C$ or above $40^{\circ}C$, the removal efficiency of total phosphorous decreased. Among the various processes, biofilm filter process A gave the highest removal efficiency of 96.4%. Pilot tests of total phosphorus removal using farm wastewater from the biofilm filter process A were carried out for 60 days under optimal conditions. When Acinetobacter sp. Lee-11 was used, the average removal efficiency in the p-adsorption area was only 32.5%, and the removal efficiencies of chemical oxygen demand (COD) and biological oxygen demand (BOD) were 56.7 and 62.5%, respectively. On the other hand, when Chromobacterium LEE-38 was used, the average removal efficiency was 95.1%, and the removal efficiencies of COD and BOD were 91.3 and 93.2%, respectively.