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AN EXPERIMENTAL STUDY OF ELECTROPHYSIOLOGICAL AND HISTOLOGICAL ASSESSMENT ON THE INJURY TYPES IN RABBIT INFERIOR ALVEOLAR NERVE (가토의 하치조 신경 손상 형태에 따른 전기생리학적 및 조직학적 변화에 관한 실험적 연구)

  • Lee, Jae-Eun;Lee, Dong-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.4
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    • pp.679-700
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    • 1996
  • Inferior alveolar nerve dysfunction may be the result of trauma, disease, or iatrogenic injury. Inferior alveolar nerve injury is inherent risk in endodontic therapy, orthognathic surgery of the mandible, and extraction of mandibular teeth, particularly the third molars. The sensory disturbances of inferior alveolar nerve associated with such injury have been well documented clinical problem that is commonly evaluated by several clinical sensory test including Tinels sign, Von Frey test(static light touch detection), directional discrimination, two-point discrimination, pin pressure nociceptive discrimination, and thermal test. These methods used to detect and assess inferior alveolar nerve injury have been subjective in nature, relying on the cooperation of the patients. In addition, many of these techniques are sensitive to differences in the examiners experience and skill with the particular technique. Data obtained at different times or by different examiners are therefore difficult to compare. Prior experimental studies have used electro diagnostic methods(sensory evoked potential) to objectively evaluate inferior alveolar nerve after nerve injury. This study was designed with inferior alveolar nerve of rabbit. Several types of injury including mind, moderate, severe compression and perforation with 19 gauze, 21 gauze needle and 6mm, 10mm traction were applied for taking the sesory evoked ppterntial. Latency and amplitude of injury rabbit inferior alveolar nerve were investigated with sensory evoked potential using unpaired t-test. The results were as follows : 1. Intensity of threshold (T1) was $128{\pm}16{\mu}A$ : latency, $0.87{\pm}0.07$ microsecond : amplitude, $0.4{\pm}0.1{\mu}V$ : conduction velocity, 23.3 m/s in sensory evoked potential of uninjured rabbit inferior alveolar nerve. 2. Rabbit inferior alveolar nerve consists of type II and III sensory nerve fiber. 3. Latency was increased and amplitude was decreased in compression injury. The more injured, the more changed in latency and amplitude. 4. Findings in perforation injury was similar to compression injury. Waveform for sensory evoked potential improved by increasing postinjured time. 5. Increasing latency was prominent in traction injury rabbit inferior alveolar nerve. 6. In microscopic histopathological findings, significant degeneration and disorganization of the internal architecture were seen in nerve facicle of severe compression and 10mm traction group. From the above findings, electrophysiological assessment(sensory evoked potential) of rabbit injured inferior alveolar nerve is reliable technique in diagnosis and prognosis of nerve injury.

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Design and Implementation of Wideband Patch Antenna with Folded and Shorted Structure for 5 GHz WLAN (폴디드 구조와 단락 구조를 이용한 5 GHz 무선 랜용 광대역 패치 안테나 설계 및 구현)

  • Kim Yong-Hee;Han Jun-Hee;Lee Won-Kew;Yang Woon-Geun
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.17 no.8 s.111
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    • pp.760-766
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    • 2006
  • In this paper, we present a wideband patch antenna with folded and shorted structure for 5 GHz WLAN(Wireless Local Area Network). The proposed antenna used folded and shorted structure in the rectangular patch for miniaturization and wide frequency bandwidth. The antenna was designed by using 3D simulation program, HFSS(High Frequency Structure Simulator) software of the Ansoft company and the implemented antenna was measured by using HP 8720c network analyzer and far field measurement chamber. Simulation result on the return loss shows fairly good characteristic of at least 13.41dB in whole frequency range of interests, and the 10dB bandwidth is 1,523MHz which shows wide bandwidth characteristic. And the simulated maximum gain of the proposed antenna is 6.57 dBi at 5.825GHz. Measured result for the 10dB bandwidth of the implemented folded and shorted structure antenna is 1,377 MHz. Measured maximum gain of the implemented antenna is 6.87dBi at 5.775GHz. Measured results for the implemented antenna showed applicable performances for the 5 GHz WLAN.

Improvement of Phase Noise for Oscillator Using Frequency Locked Loop (주파수 잠금회로를 이용한 발진기의 위상잡음 개선)

  • Kim, Wook-Lae;Lee, Chang-Dae;Kim, Yong-Nam;Im, Pyung-Soon;Lee, Dong-Hyun;Yeom, Kyung-Whan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.27 no.7
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    • pp.635-645
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    • 2016
  • In this paper, we showed the phase noise of voltage controlled oscillator(VCO) can be radically improved using FLL(Frequency Locked Loop). At first, a 5 GHz VCO is fabricated using a hair-pin resonator. The fabricated VCO shows a phase noise of -53.1 dBc/Hz at 1 kHz frequency offset. In order to improve the phase noise of the fabricated VCO, a FLL is constructed using the feedback loop that consists of the VCO, a frequency detector composed of 5 GHz resonator, loop-filter, and level shifter. The fabricated FLL is designed to oscillate at a frequency of 5 GHz, and its measured phase noise is about -120.6 dBc/Hz at 1 kHz offset frequency. As a result, the phase noise of VCO can be radically improved by about 67.5 dB applying FLL. In addition, the measured phase noise performance is close to that of crystal oscillator.

X-RAY ASTRONOMY EXPERIMENT ON THE INDIAN SATELLITE IRS-P3

  • AGRAWAL P. C.;PAUL B.;RAO A. R.;SHAH M. R.;MCKERJEE K.;VARIA M. N.;YADAV J. S.;DEDHIA D. K.;MALKAR J. P.;SHAH P.;DAMLE S. V.;MARAR T. M. K.;SEETHA S.
    • Journal of The Korean Astronomical Society
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    • v.29 no.spc1
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    • pp.429-432
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    • 1996
  • An x-ray astronomy experiment consisting of three collimated proportional counters and an X-ray Sky Monitor (XSM) was flown aboard the Indian Satellite IRS-P3 launched on March 21, 1996 from SHAR range in India. The Satellite is in a circular orbit of 830 km altitude with an orbital inclination of $98^{\circ}$ and has three axis stabilized pointing capability. Each pointed-mode Proportional Counter (PPC) is a multilayer, multianode unit filled with P-10 gas ($90\%$ Ar + $10\%\;CH_4$) at 800 torr and having an aluminized mylar window of 25 micron thickness. The three PPCs are identical and have a field of view of $2^{\circ}{\times}2^{\circ}$ defined by silver coated aluminium honeycomb collimators. The total effective area of the three PPCs is about 1200 $cm^2$. The PPCs are sensitive in 2-20 keV band. The XSM consists of a pin-hole of 1 $cm^2$ area placed 16 cm above the anode plane of a 32 cm$\times$32 cm position sensitive proportional counter sensitive in 3-8 keV interval. The position of the x-ray events is determined by charge division technique using nichrome wires as anodes. The principal objective of this experiment is to carry out timing studies of x-ray pulsars, x-ray binaries and other rapidly varying x-ray sources. The XSM will be used to detect transient x-ray sources and monitor intensity of bright x-ray binaries. Observations of black-hole binary Cyg X-1 and few other binary sources were carried out in early May and July-August 1996 period. Details of the x-ray detector characteristics are presented and preliminary results from the observations are discussed.

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A Study on Fracture Behavior of Center Crack at Unidirectional CFRP due to Stacking Angle (적층각도에 따른 단방향 CFRP에서의 중앙 크랙의 파괴 거동에 관한 연구)

  • Park, Jae-Woong;Cheon, Seong-Sik;Cho, Jae-Ung
    • Composites Research
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    • v.29 no.6
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    • pp.342-346
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    • 2016
  • Carbon fiber reinforced plastic (CFRP), one of lightweight materials, is the fiber structure using carbon fiber. It is the composite material that has the characteristics of carbon and plastic. As for the fiber structure, it has the great strength due to fiber direction. CFRP for woven type is used mostly as such a CFRP with lightweight. Woven type is more stable when compared with unidirectional type. On the other hand, woven type is highly priced. Therefore, this study aims to analyze the fiber structure of unidirectional CFRP. In this study, as the stacking angle [0/X/-X/0], X is the variable. This is unidirectional CFRP in which the angle phase of X has been reversed and stacked. By using such a unidirectional CFRP, the analysis model which had a crack at the center as the form of panel with the thickness of 2 mm was used. On analysis, the load is applied on the upper and lower parts being connected with a pin. The damage in the area near center crack was investigated. As for the analysis model, 3D surface model was designed by using CATIA. For CFRP stacking, the stacking direction was determined by using ACP in ANSYS program and the analysis model with two stacks was made. Afterwards, the structural analysis was carried out.

A Study on the Development of High-sensitivity AEC-sensor for Minimization of Dose Creep in Diagnostic Imaging System (진단영상 시스템에서 선량크리프 현상의 최소화를 위한 고감도 AEC 센서에 관한 연구)

  • Kim, Kyo-Tae;Han, Moo-Jae;Heo, Ye-Ji;Kim, Joo-Hee;Kang, Sang-Sik;Park, Ji-Koon;Nam, Sang-Hee
    • Journal of the Korean Society of Radiology
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    • v.10 no.5
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    • pp.321-325
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    • 2016
  • Dose creep is one of clinical errors that arises from the tester's inexperience or carelessness, and according to Task Group #116 of American Association of Physicists in Medicine, its continued occurrence is being reported in the digital method. At this point, the demand for an automatic exposure control device that minimizes the dose creep phenomenon and can improve reproducibility is increasing. In this study is to consider the automatic exposure control device sensor that can is not only easy to produce, but also reduce the dose creep phenomenon by conducting a research on high-efficient semiconductor sensor. As a result, the Intrinsic-type and PIN-type sensors have excellent optical property compared to Ref sensor, would have less shading effect, and have relatively low sensitivity, but would provide accurate feedback signals to automatic exposure control device with its consistent tendency according to exposure condition changes.

Menadione Sodium Bisulfite-Protected Tomato Leaves against Grey Mould via Antifungal Activity and Enhanced Plant Immunity

  • Jo, Youn Sook;Park, Hye Bin;Kim, Ji Yun;Choi, Seong Min;Lee, Da Sol;Kim, Do Hoon;Lee, Young Hee;Park, Chang-Jin;Jeun, Yong-Chull;Hong, Jeum Kyu
    • The Plant Pathology Journal
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    • v.36 no.4
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    • pp.335-345
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    • 2020
  • Tomato grey mould has been one of the destructive fungal diseases during tomato production. Ten mM of menadione sodium bisulfite (MSB) was applied to tomato plants for eco-friendly control of the grey mould. MSB-reduced tomato grey mould in the 3rd true leaves was prolonged at least 7 days prior to the fungal inoculation of two inoculum densities (2 × 104 and 2 × 105 conidia/ml) of Botrytis cinerea. Protection efficacy was significantly higher in the leaves inoculated with the lower disease pressure of conidial suspension compared to the higher one. MSB-pretreatment was not effective to arrest oxalic acid-triggered necrosis on tomato leaves. Plant cell death and hydrogen peroxide accumulation were restricted in necrotic lesions of the B. cinereainoculated leaves by the MSB-pretreatment. Decreased conidia number and germ-tube elongation of B. cinerea were found at 10 h, and mycelial growth was also impeded at 24 h on the MSB-pretreated leaves. MSB-mediated disease suppressions were found in cotyledons and different positions (1st to 5th) of true leaves inoculated with the lower conidial suspension, but only 1st to 3rd true leaves showed decreases in lesion sizes by the higher inoculum density. Increasing MSB-pretreatment times more efficiently decreased the lesion size by the higher disease pressure. MSB led to inducible expressions of defence-related genes SlPR1a, SlPR1b, SlPIN2, SlACO1, SlChi3, and SlChi9 in tomato leaves prior to B. cinerea infection. These results suggest that MSB pretreatment can be a promising alternative to chemical fungicides for environment-friendly management of tomato grey mould.

Comparison of the Nutritional Composition for Bokkeumbap Products in High-Frequency Processed Foods in the Republic of Korea (국내 다빈도 가공식품 중 볶음밥류의 영양성분 함량 비교)

  • Jung, Ui-Hwan;Cha, Seung-Hyeon;Kim, Byung Hee;Yoon, Sung-Won;Kim, In Hwan;Chun, Jiyeon;Lee, Ki-Teak;Kim, Younghwa;Shin, Eui-Cheol;Seo, Dongwon;Lee, Sam-Pin;Lee, Junsoo;Jang, Keum-Il
    • The Korean Journal of Food And Nutrition
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    • v.32 no.6
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    • pp.589-597
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    • 2019
  • In this study, 70 kinds of nutritional composition for five bokkeumbap products(spicy chicken, shrimp(saeu), haemul, nakji, and barbecue bokkeumbap) in high-frequency processed foods were analyzed. Raw data of intake amounts were collected from the 7th Korea National Health and Nutrition Examination Survey. Regarding proximate composition, spicy chicken bokkeumbap had lower water content and higher carbohydrate content than other bokkeumbaps, resulting in the highest total calories. The proximate composition of other bokkeumbaps were all distributed within a similar range. Vitamin content differed according to ingredients added to the bokkeumbaps. Haemul bokkeumbap had high content of vitamins B1 and B2, nakji bokkeumbap had high content of vitamin C and β-carotene, and barbecue bokkeumbap had high content of total niacin, folic acid, and vitamin A. For mineral content, barbecue bokkeumbap showed the highest content distribution, while nakji bokkeumbap showed the lowest content distribution. Regarding fatty acid and fat content, the highest content of fatty acids, saturated fats, and trans fats was detected in shrimp(saeu) bokkeumbap. For amino acid content, barbecue bokkeumbap showed highest content distribution. These results can be used as salient basic data for a food nutrient composition database and to significantly contribute to consumers' health.

Biochemical Compositions of Follicular Fluid and the Effects of Culture Conditions on the In Vitro Development of Pig Oocytes

  • Huang, Wei-Tung;Lu, She-Ghi;Tang, Pin-Chi;Wu, Shinn-Chih;Cheng, San-Pao;Ju, Jyh-Cherng
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.10
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    • pp.1403-1411
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    • 2002
  • The aims of this study were, firstly, to analyze the biochemical compositions of serum and follicular fluid (FF) from prepubertal gilts after PMSG (1,000 IU) treatment. The concentrations of total proteins, lipids, cholesterol, glucose and sex hormones (progesterone, $P_4$; estradiol-$17{\beta}$, $E_2$; testosterone, T) were measured. Secondary, the effects of porcine FF (pFF) addition (40% and 100%) in IVM media and different culture conditions [Exp. 1: mBMOC-2+20% porcine serum (PS), fresh IVM medium, filtered IVMconditioned medium, or rabbit oviducts; Exp. 2: mBMOC-2+20%PS or stepwise medium replacement procedures (SMRP) cocultured with or without cumulus cells] on the in vitro development (IVD) of porcine oocytes were also examined. Results showed that no significant differences were found in total protein levels between serum and pFF from different sizes (large, >7 mm; medium, ~5-7 mm; small, <3-5 mm) of follicles (75-85 and 49-90 mg/dl; p>0.05). Total lipid concentrations remained constant in serum (395-472 mg/dl), and reduced significantly in the pFF from large follicles (287 mg/dl) at 132 h after PMSG treatment when compared to those at other time points (441-480 mg/dl). Basal cholesterol levels in serum and pFF at 12 h were similar (153-161 mg/dl), but increased at 36 h (186-197 mg/dl). Basal P4 and E2 levels in serum (0.1 ng/ml and 5.5 pg/ml) were low, but increased from 0.34 ng/ml and 12.13 pg/ml at 24 h to 0.81 ng/ml and 61.70 pg/ml at 98 h, respectively, after PMSG treatment (p<0.05). P4 levels increased linearly in pFF from large follicles during 12 through 132 h (138-1,288 ng/ml). A similar increase was also observed in $E_2$ levels (22-730 pg/ml) before 60 h post PMSG treatment, and then dropped afterwards (730-121 pg/ml). The development of the oocytes fertilized in 40% pFF-medium was greater than that in 100% pFF-medium group without gonaodtropin addition (31% vs 10%, p<0.05). However, both were lower than those in mBMOC-2+20%PS and in rabbit oviducts (p<0.05). When cocultured with cumulus cell monolayers, a greater cleavage rate was observed in the group cultured in filtered IVM-conditioned medium than the SMRP group (36% vs 18%, p<0.05). A similar phenomenon was also observed in the culture without cumulus cell monolayers (33% vs 19%, p<0.05). It is concluded that neither the fresh IVM nor filtered IVM-conditioned medium has positive effect on the IVD of oocytes. Coculture with cumulus cell monolayers and the SMRP were not beneficial to the development of IVF pig oocytes.

Predictors of Positive Bone Metastasis in Newly Diagnosed Prostate Cancer Patients

  • Chien, Tsu-Ming;Lu, Yen-Man;Geng, Jiun-Hung;Huang, Tsung-Yi;Ke, Hung-Lung;Huang, Chun-Nung;Li, Ching-Chia;Chou, Yii-Her;Wu, Wen-Jeng;Huang, Shu-Pin
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1187-1191
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    • 2016
  • Background: The prevalence of prostate cancer (PCa) has been increasing in recent years. Treatment strategies are largely based on the results of bone scan screening. Therefore, our aim was to investigate predictors of positive bone metastasis in newly diagnosed PCa patients. Materials and Methods: After extensive review, 336 consecutive patients newly diagnosed with PCa between April 2010 and November 2013 at our institution were enlisted in the study. Patients were divided into two groups according to bone scan results. Univariate analyses (Chi-square test for discrete variables and independent t-test for continuous variables) were applied to determine the potentially significant risk factors associated with distant bone metastasis. Binary logistic regression analyses were used to further investigate the influence of these factors on bone metastasis. Results: The patient mean age was $71.9{\pm}8.6years$ (range: 48 to 94 years). The mean prostate specific antigen (PSA) level and biopsy Gleason score were $260.2{\pm}1107.8ng/mL$ and $7.4{\pm}1.5$, respectively. The body mass index (BMI) for the series was $24.5{\pm}3.4kg/m^2$. Sixty-four patients (19.0%) had a positive bone scan result. Patients with positive bone scan results had a significantly lower BMI ($23.3{\pm}3.5$ vs. $24.8{\pm}3.3$; p=0.003), a higher Gleason score ($8.5{\pm}1.1$ vs. $7.1{\pm}1.5$; p < 0.001), and a higher PSA level ($1071.3{\pm}2337.1$ vs. $69.4{\pm}235.5$; p < 0.001) than those without bone metastasis. Multivariate logistic regression analysis employing the above independent predictors demonstrated that a Gleason score of ${\geq}7$, clinical stage ${\geq}T3$, $BMI{\leq}22kg/m^2$, and an initial PSA level of ${\geq}20ng/mL$ were all independent predictors of bone metastasis. Conclusions: A bone scan might be necessary in newly diagnosed PCa patients with any of the following criteria: clinical stage T3 or higher, a Gleason score of 7 or higher, BMI equal to or less than 22, and a PSA level of 20 or higher.