• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.5 no.1
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• pp.119-136
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• 1999

Anti-cancer medi-alcohols in oriental herb prescriptions were divided by chef effects. Each medi-alcohols were analyzed and studied abut frequency, character, target, effect. Also, they were divided into the method of making medi-alcohols. The results were summerized as follows. 1. The department of using medi-alcohol in anticancer herbal scriptions were limited in gynecology, dermatology and digestive internal medicine. There were a lot in gynecology. 2. In analysis about medi-alcohols of dermato scriptions by chef effect, the herbs of relieving exterior syndrome were a lot first and the herbs of invigorating-qi were second. 3. In analysis about meld-alcohols of dermato scripions by chef effect, the herbs of promoting blood circulation to remove blood stasis were a lot first and the herbs of invigorating-qi were second. 4. The method of making medi-alcohol was divided into four types ; boiling, making up pills, extration, filtration. I hope that the medi-alcohol will be used as practional references.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.451-455
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• 2015

More than one million new patients suffer from breast cancer annually in the world. In developed countries, breast cancer is the most common malignancy diagnosed among women, and in developing regions, it often ranks second to cervical cancer. This study aimed to investigate the relationship between incidence of breast cancer and reproductive factors in North-West of Iran. This retrospective analytical control-case study was conducted with 235 breast cancer patients and 235 women in the control group. Data collection tools included a set of questions with interviews and patient medical records. Data were analyzed using statistical tests: t-test, Chi-square, Fisher, and Pearson correlation coefficient. Significantly increased risks were associated between breast cancer and older age at first pregnancy, age at menopause and history of contraceptive use. A trend for decreasing risk were observed with increasing parity. Findings of this study showed no association between breast cancer and age at menarche. The study results suggested that physiological and reproductive factors may play important roles in the development breast cancer among Iranian women.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.599-602
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• 2013

Objectives: To evaluate the frequency of cytohistologic discrepancy of high-grade squamous intraepithelial lesions (HSILs) in Pap smears and associated factors. Methods: Medical records of 223 women with HSIL Pap smears who were treated at Thammasat University Hospital were reviewed. Data on age, parity, menopausal status, contraceptive use and colposcopic directed biopsy and loop electrosurgical excision procedure (LEEP) pathology results were recorded. Results: Mean (SD) age of patients was 38.0 (9.4) years. The majority were premenopausal (86.5%) and multiparous (83.9%). Cytohistologic discrepancy between the Pap test and colposcopic-directed biopsy histology was 45.7% and that between the Pap test and LEEP histology was 29.5%. Fifty-four (24.2%) women had no high-grade CIN on both colposcopic directed biopsy and LEEP. Nulliparity, postmenopausal status and having no oral contraceptive pills use were factors associated with cytohistologic discrepancy. Conclusion: The exact cytohistologic discrepancy rate was relatively high (24.2%). Factors associated with cytohistologic discrepancy were nulliparity and postmenopausal status and having no oral contraceptive pill use.

• Advances in Traditional Medicine
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• v.2 no.1
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• pp.28-35
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• 2002

Toad venom, 'Chan su' in Chinese and 'somso' in Korean, is a well-known traditional oriental medicine obtained from the skin venom gland of the toad. Formulations of toad venom have been widely applied in China, Japan, Korea and other oriental countries for a long time. It is often found in traditional Chinese formulations, such as Jiuxin (or Kyushin in Japan), Yixin, Huoxin, Shexiang baoxin wan, Lu shen wan and Laryngitis pills. According to a pharmaceutical chemistry study, toad venom contains multiple biological active substances, such as bufalin, resibufogenin and cinobufagin. Modern pharmacological studies indicated that toad venom has multiple pharmacological actions, including acting as a cardiotonic, antitumor local anesthetic effects, stimulates the respiratory center, vasopressor action, anti-inflammatory and diuretic effects. Like other medications, toad venom also has certain toxicity and adverse effects, for example, inducing delayed afterdepolarization and triggered arrhythmia. The major chemical constituents, basic pharmacological actions and adverse reactions of toad venom are discussed in this article.

• Advances in Traditional Medicine
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• v.9 no.1
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• pp.39-48
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• 2009

We have evaluated the effect of long term treatment of Enicostemma littorale (E. littorale) in type 2 diabetic patients taking pills of aqueous extract of E. littorale regularly as a complimentary medicine for at least 9 months. The effects of E. littorale on glycemic control, lipid profile, cardiac function and DNA damage in these patients were compared with those who had not been regular in taking E. littorale but regular in taking other conventional anti-diabetics. Our data suggest that, E. littorale can maintain normal blood glucose, serum insulin, serum triglycerides levels of type 2 diabetic patients if taken regularly. E. littorale also improves insulin sensitivity, and normalize disturbed lipogram and elevated creatinine levels, thereby produces beneficial effect in preventing cardiovascular complications and may preserve the kidney function. The finding that E. littorale also prevents DNA damage suggest a long term effect in diabetic patients. E. littorale thus can be considered as safe supplementary therapy for a long term and effective management of type 2 diabetic patients.

• Journal of the Korean Dietetic Association
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• v.4 no.2
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• pp.145-151
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• 1998

The purpose of this study was to investigate the related factors to child overweight through investigation of children aged 6-12. Data on physical examinations, family history and dietary habits were obtained. Children were classified into normal(98 persons) and overweight(118 persons) group using the combination of height for age, weight for age and weight for height standard by the World Health Organization. Children's height, weight and BMI exhibited a significant difference between groups except children aged 8 for height. Unbalanced diet was a risk factors for overweight(Odd ratio : 1.765, 95% CI : 1.022~3.048). Number of brothers showed negative significance especially in two brothers compared to that of one(Odd ratio : 0.456, 95% CI : 0.209~0.995). But Birth weight, feeding practice, overeating, taking nutrition pills, sleeping time, mother's education level and employmental status didn't have any difference. We found out there were different risk factors between obese and overweight group. They should be divided into different groups in studying risk factors. And we should pay much attention to overweight children in order to prevent improving to obesity.

• Journal of Haehwa Medicine
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• v.22 no.2
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• pp.103-110
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• 2014

Objective : Western sleeping pills work very fast and effectively against insomnia. But they also bring about many side effects. Therefore oriental medicine can be a good alternative remedy. There are many clinical reports about patients treated for insomnia after stroke using oriental medicine. However, there are no clinical report about patients treated for insomnia after stroke diagnosed by Gobub & Bokjin. We want to prove the effect of Gobub & Bokjin in diagnosis and treatment for the insomnia patients after stroke. Methods : We chosed a patient who had suffered from insomnia after stroke. We administered acupuncture treatment, as well as Herbal medicine(Bokryoungum and Sanjoinsan). We monitored total sleep time per a day for 23 days. Results & Conclusion : Bokryoungum and Sanjoinsan was effective in improving overall sleep time day.

• The Journal of Internal Korean Medicine
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• v.37 no.5
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• pp.822-830
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• 2016

Objective: To report the effect of Gamiguibi-tang (加味歸脾湯) as a treatment for insomnia. Methods: An insomnia patient who scored 27 points for her insomnia severity index was enrolled in this study. She received oriental treatment with herbal medication (Gamiguibi-tang), acupuncture, and moxibustion for 1 month. Results: After treatment, sleep duration and sleep quality were improved. After the patient had taken Gamiguibi-tang, her score for the Pittsburgh Sleep Quality Index (PSQI) decreased from 21 to 9, and associated symptoms were also improved without taking sleeping pills. Conclusions: Gamiguibi-tang is effective for the treatment of insomnia. More clinical data and studies are required in patients suffering from insomnia.

• Women's Health Nursing
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• v.16 no.4
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• pp.399-408
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• 2010

Purpose: The purpose of this study was to investigate differences of subjective, objective knowledge and educational need about contraceptives according to sex in college students. Methods: Data were collected by a self-administered questionnaire from 84 male and 111 female college students on May, 2008. PASW 18.0 program was used for data analysis. Results: There were significant differences in age, major, grade, place of residence, and experience of sexual intercourse between male and female college students. There was a significant difference in objective knowledge about contraceptives between the two groups, but no significant difference in subjective knowledge. The positive correlation was shown between subjective and objective knowledge about contraceptives. Even when demographic variables such as age, major, grade, place of residence, and experience of sexual intercourse were controlled, sex was a significant influencing factor on subjective and objective knowledge about contraceptives. Educational need about emergency contraceptive pills was significantly different and ranking of educational need about contraceptives was also different between the two groups. Conclusion: These results suggest that different education programs according to sex are needed to maximize the effect of contraceptive education and sexual characteristics are considered to give an education to college students.

• Journal of Nutrition and Health
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• v.32 no.1
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• pp.40-49
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• 1999

This study was conducted with 20 female gymnasts and 23 age-matched controls to examine pattern, weight control behavior and nutritional status. Most gymnasts(95.0%) reported that they used weight-control methods, while relatively few age-matched controls employed these methods. These methods included sauna(95.0%), food restriction(90.0%), excess exercise (70.0%), laxative abuse(10%) and use of diet pills(10%). Gymnasts had significantly (p<0.05) lower scores for statements related to 'sneaking food', 'vomiting after overeating', showing more negative eating behavior than age-matched controls. Energy intake of gymnasts was 968.9$\pm$421.4kcal while energy expenditure was 2,091$\pm$361kcal, showing negative evergy balance(-1,1225$\pm$534.6kcal). Female gymnasts consumed less than 70% of the RDA for protein, calcium, iron, vitamin A, thiamin, riboflavin and niacin, which reflects their low energy intake. The average intakes of calcium, iron, vitamin A, thiamin, riboflavin and niacin did not meet the recommended dietary allowances for their age groups. Adolescent athletes who train vigorously and consume a low-energy diet may be exposed to an increase in potential health risks. Therefore, individuals who advise athletic adolescents regarding training and dietary habits need to emphasize the importance of consuming an appropriate energy intake to support performance as well as growth and development. The sports nutritionist is in a position to convey such information to coaches, physicians, parents and to the athletes themselves.