• Journal of Animal Environmental Science
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• v.13 no.2
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• pp.89-96
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• 2007

The aim of this study was to investigate the effect of parity and postpartum day on the behavior of nursing sows and their suckling piglets. Total 36 Landrace or Yorkshire sows(range of parity: 1 to 8) and their litters(range of litter size: 11 to 13 piglets) were assigned with sow's parity($1{\sim}2,\;3{\sim}4$ and 5 or more) and sow's postpartum days(day 1, 7, 14 and 21). The sows were housed in farrowing crates($0.6{\times}2.1m$) located in pens($2.4{\times}1.8m$) with totally perforated flooring. The sows and piglets were conventionally managed. The sows and their piglets behaviors were recorded during the 24 hour period at 1, 7, 14 and 21 days of postpartum. The obtained results from this study were as follows; 1. All the nursing sows in both group made attempts for lateral tying more than for other behaviors for whole days. The order of behavioral frequency at 1 and 3 weeks postpartum according the days of postpartum of sows was lateral tying, ventral lying, standing, sitting, feeding and drinking. The nursing sows at day 1 postpartum spent more time on sitting and standing than the sows at day 7 or more postpartum. 2. The parity of sows did not affected the lateral tying and sitting behavior of nursing sows, however the ventral tying are lowed in $1{\sim}2$ parity of sow group than the other parity group. Standing, feeding and drinking behavior of sows was not showed at any trends according to the sow's parity. 3. In the behaviors of suckling piglets, lying was increased and unsuccessful suckling was decreased until 21 days postpartum. Compared to the 7, 14 and 21 day postpartum, piglets at the 1 day postpartum spent less time for lying and walking, whereas they spent much more time for unsuccessful suckling. 4. According th the sow's parity, their piglets tying and unsuccessful suckling was lowed in $1{\sim}2$ parity sow group, however more than 3 parity sow's piglets behavior are not affected.

• Korean Journal of Veterinary Research
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• v.21 no.2
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• pp.87-91
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• 1981

OK serogroups of 268 cultures of Escherichia coli isolated from piglets with colibacillary diarrhea were determined by the use of the simplified routine diagnostic procedures of Sojka. The results obtained are summarised as follows: 1. Of 268 cultures of Escherichia coli tested, 190 cultures were classified into 15 OK groups and the remaining 78(29.1%) were untypable. 2. The most frequently isolated enteropathogenic E. coli in order of prevalence were 0157 : K 'Vl7' (14.2%), 0149 : K91, K88a, c (13.7%), 064 : K 'V142' (11.6%), 08 : K87, K88a, b (10.5%) and O141 : K85a, b, K88a, b (7.9%).

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2003.10a
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• pp.31-31
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• 2003

Porcine circovirus (PCV) is the smallest virus that replicates autonomously in mammalian cells. PCV2 is recongized as the casual agent of postweaning multisystemic wasting syndrome (PMWS).[1] Although the role of PCV2 in reproductive failure requires further clarification, there have been several reports of PCV2-associated reproductive failure. Consistent clinical signs of affected farms include elevated abortion, stillbirths and fetal mummification. The objective of this study was to determine the prevalence of PCV2 in aborted fetuses and stillborn piglets. Second objective was to determine the distribution of PCV2 DNA and antigen in aborted fetuses and stillborn piglets by in situ hybridisation and immunohistochemistry. (omitted)

• Korean Journal of Veterinary Research
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• v.60 no.4
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• pp.241-244
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• 2020

Three neonatal pigs from the same litter in a domestic farm were born with skin lesions. Grossly, multiple well-circumscribed, round papules distributed over the skin of the three piglets. Two piglets were submitted for a diagnosis of skin disease. Microscopically, epidermal hyperplasia with ballooning degeneration of stratum spinosum keratinocytes was observed. Some keratinocytes contained eosinophilic intracytoplasmic inclusions and a central nuclear vacuole and chromatin margination. Swinepox (SWP) virus was detected by polymerase chain reaction and nucleotide sequencing, and Staphylococcus hyicus was isolated in skin lesions. Based on the gross findings and laboratory results, these piglets were diagnosed with congenital SWP with a secondary staphylococcal infection.

• Korean Journal of Organic Agriculture
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• v.21 no.3
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• pp.423-435
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• 2013

The Codonopsis pilosula is traditional oriental herb associated with immune-modulatory functions and has anti-inflammatory properties and antioxidative activity. The present study was conducted to investigate the effects of dietary supplementation of Codonopsis pilosula extract powder (CEP) on the immunity and productivity in sows and piglets. A total of 20 pregnant sows were randomly assigned to two dietary treatments, which was given a corn-soybean meal diet with 0% and 0.5% CEP from 40 days prepartum to weaning (25 days postpartum). The immune system of piglets was expected to build up, because the feeding of CEP might increase the colostrum contents in sows. We also predicted that the growth performance of piglets also could be increased by some compensation effects due to the increased immunity of piglets. In results, immunities of sows and piglets as well as growth performance of piglets were not affected by the supplementation of CEP. The correlation between the colostrum and the serum on the IgG contents tended to have a positive correlation, although there was no significant (coefficient, 0.435; P=0.102). This result suggests that the supplementation of CEP may increase IgG contents in sows and piglets and contribute to improve immunity of piglets. In conclusion, it is thought that the physiologically active substances of CEP did not influence to the immune synergic effects in vivo of sows. Thus, the metabolic and action mechanism of the physiologically active substances of CEP should be explored to evaluate the availability of CEP as a feed additive for the immunomodulator.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.7
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• pp.1035-1043
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• 2014

To investigate the effect of dietary Acanthopanax senticosus polysaccharide (ASPS) on growth performance, immunity, blood parameters and mRNA expression of pro-inflammatory cytokines in immunologically challenged piglets, an experiment employing $2{\times}2$ factorial arrangement concerning dietary ASPS treatment (0 or 800 mg/kg) and immunological challenge (lipopolysaccharide [LPS] or saline injection) was conducted with 64 crossbred piglets (weaned at 28 d of age, average initial body weight of $7.25{\pm}0.21kg$) assigned to two dietary ASPS treatments with 8 replicates of 4 pigs each. Half of the piglets of per dietary treatment were injected with LPS or saline on d 14. Blood samples were obtained at 3 h after immunological injection on d 14 and piglets were slaughtered to obtain spleen samples on d 21. Dietary ASPS did not affect average daily gain (ADG) (p = 0.634), average daily feed intake (ADFI) (p = 0.655), and gain:feed (p = 0.814) prior to LPS challenge. After LPS challenge, for LPS-challenged pigs those fed ASPS had higher ADG and ADFI than the non-supplemented group (p<0.05), and an interaction between $LPS{\times}ASPS$ was observed on the two indices (p<0.05). Dietary ASPS improved lymphocyte proliferation among saline-injected and LPS-injected pigs (p<0.05). Interaction between $LPS{\times}ASPS$ was also revealed on lymphocyte proliferation (p<0.05). Circulatory concentration of IgG was influenced neither by ASPS (p = 0.803) or LPS (p = 0.692), nor their interaction (p = 0.289). Plasma concentration and spleen mRNA expression of interleukin-1beta (IL-$1{\beta}$), interleukin-6 (IL-6), and tumor necrosis factor (TNF)-${\alpha}$ were induced to increase (p<0.05) by LPS challenge, in contrast, these indices were decreased by dietary ASPS (p<0.05), and interactions were found on these cytokines (p<0.05). For LPS-challenged pigs, dietary ASPS also reduced the circulating concentration and spleen mRNA expression of IL-$1{\beta}$, IL-6 as well as TNF-${\alpha}$ (p<0.05). The interaction between $LPS{\times}ASPS$ was also observed on the circulating concentration of insulin-like growth factor-I, ${\alpha}$-acid glycoprotein (${\alpha}$-AGP), nonesterified fatty acid, and glucose (p<0.05). The results of this study demonstrate that dietary ASPS can modulate the release of pro-inflammatory cytokines during immunological challenge, which might enable piglets to achieve better growth performance.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.5
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• pp.707-714
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• 2008

The experiment was conducted to evaluate the effect of ${\beta}$-1,3/1,6-glucan on growth performance, immunity and endocrine responses of weanling piglets. One hundred and eighty weanling piglets (Landrace$\times$Large White, $7.20{\pm}0.25kg$ BW and $28{\pm}2$ d of age) were randomly fed 1 of 5 treatment diets containing dietary ${\beta}$-1,3/1,6-glucan supplemented at 0, 25, 50, 100 and 200 mg/kg for 4 wks. Each treatment was replicated in 6 pens containing 6 pigs per pen. On d 14 and 28, body weight gain, feed consumption and feed efficiency were recorded as measures of growth performance. Peripheral blood lymphocyte proliferation and serum immunoglobulin G (IgG) were measured to study the effect of dietary ${\beta}$-1,3/1,6-glucan supplementation on immune function. Plasma prostaglandin E2 (PGE2), growth hormone (GH) and ghrelin were measured to investigate endocrine response to ${\beta}$-1,3/1,6-glucan supplementation. Our results suggest that average daily gain (ADG) and feed efficiency had a quadratic increase trend with dietary ${\beta}$-1,3/1,6-glucan supplementation from d 14 to 28, whereas it had no significant effect on average daily feed intake (ADFI). The treatment group fed with 50 mg/kg dietary ${\beta}$-1,3/1,6-glucan supplementation showed a numerical increase in ghrelin, a similar change trend with ADG and no significant effect on GH. Lymphocyte proliferation indices, serum IgG and plasma PGE2 concentrations varied linearly with dietary supplementation levels of ${\beta}$-1,3/1,6-glucan on d 14. Higher levels of ${\beta}$-1,3/1,6-glucan may have a transient immuno-enhancing effect on the cellular and humoral immune function of weanling piglets via decreased PGE2. Taking into account both immune response and growth performance, the most suitable dietary supplementation level of ${\beta}$-1,3/1,6-glucan is 50 mg/kg for weanling piglets.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.5
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• pp.723-731
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• 2008

Immunomodulatory feed additives might offer alternatives to antimicrobial growth promoters in pig production. This experiment was designed to determine the effects of dietary galacto-mannan-oligosaccharide (GMOS) and chitosan oligosaccharide (COS) supplementation on the immune response in early-weaned piglets. Forty 15-day-old piglets (Duroc$\times$Landrace$\times$Yorkshire) with an average live body weight of $5.6{\pm}0.51kg$ were weaned and randomly assigned to 4 treatment groups that were fed maize-soybean meal diets containing either basal, 110 mg/kg of lincomycin, 250 mg/kg of COS or 0.2% GMOS, respectively, over a 2-week period. Another six piglets of the same age were sacrificed on the same day at the beginning of the study for sampling, in order to obtain baseline values. Interleukin (IL)-1${\beta}$gene expression in peripheral blood monocytes, jejunal mucosa and lymph nodes, as well as serum levels of IL-1${\beta}$ IL-2 and IL-6, IgA, IgG, and IgM, were evaluated for 5 pigs from each group at 15 and 28 days of age. The results indicate that weaning stress resulted in decreases in serum antibody and cytokine levels. Dietary supplementation with GMOS or COS enhanced (p<0.05) IL-1${\beta}$gene expression in jejunal mucosa and lymph nodes, as well as serum levels of IL-1${\beta}$ IL-2, IL-6, IgA, IgG and IgM compared to supplementation with lincomycin. These findings suggest that GMOS or COS may enhance the cell-mediated immune response in early-weaned piglets by modulating the production of cytokines and antibodies, which shows that GMOS or COS have different effects than the antibiotic on animal growth and health.

• Journal of Animal Science and Technology
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• v.45 no.6
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• pp.1061-1066
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• 2003

The present study was performed to investigate the effect of ozonation of the swine nursery building on indoor air quality and growth efficiency of the weanling piglets. Forty 21-day-old, cross-bred weanling piglets were housed in two ozonated or unozonated pens(10 males and 10 females per pen) for 3 wk alternately in a swine nursery building and this procedure was repeated three times. Ozone was generated using a commercial apparatus outside the nursery building and infused into the nursery building through a duct at a level of 0.03 ppm. Indoor concentrations of harmful gases were measured at 2-h intervals for a 24-h period per each 3-wk feeding trial. Indoor ammonia and carbon dioxide gas concentrations were reduced by the ozonation(P〈0.01) by 21% and 7%, respectively, compared with those of the control(unozonation), although hydrogen sulfide concentration was not affected by the treatment. However, the weight gain, feed intake and feed/gain of the piglets did not change due to the ozonation. Results suggest that ozonation of the swine nursery building is effective for improving the indoor air quality without affecting the production efficiency of weanling piglets.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.8
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• pp.1131-1140
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• 2014

This research focused on the effects of different doses of Bacillus subtilis KN-42 on the growth performance, diarrhea incidence, faecal bacterial flora, and the relative number of Lactobacillus and Escherichia coli in faeces of weaned piglets to determine whether the strain can serve as a candidate antimicrobial growth promoter. A total of 360 piglets (initial body weight $7.14{\pm}0.63$ kg) weaned at $26{\pm}2$ days of age were randomly allotted to 5 treatment groups (4 pens per treatment with 18 pigs per pen) for a 28-day trial. Dietary treatments were basal diet without any antimicrobial (negative control; NC), basal diet supplemented with 120 mg/kg feed of neomycin sulfate (positive control; PC) and basal diet supplemented with $2{\times}10^9$ (L), $4{\times}10^9$ (M) and $20{\times}10^9$ (H) CFU/kg feed of B. subtilis KN-42. During the overall period, average daily gain and feed efficiency of piglets were higher in groups PC, M, and H than those in group NC (p<0.05), and all probiotics and antibiotics groups had a lower diarrhea index than group NC (p<0.05). The 16S rDNA gene-based methods were used to analyze faecal bacterial flora on day 28 of experiment. The result of denaturing gradient gel electrophoresis analysis showed that supplementation of B. subtilis KN-42 to the diet changed the bacterial communities, with a higher bacterial diversity and band number in group M than in the other four groups. Real-time polymerase chain reaction analysis showed that the relative number of Lactobacillus were higher in groups PC and H than in group NC (p<0.05), and the supplemented B. subtilis KN-42 to the diet also reduced the relative number of E. coli (p<0.05). These results suggest that dietary addition of B. subtilis KN-42 can improve the growth performance and gastrointestinal health of piglets.