Effects of Bacillus subtilis KN-42 on Growth Performance, Diarrhea and Faecal Bacterial Flora of Weaned Piglets |
Hu, Yuanliang
(State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University)
Dun, Yaohao (State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University) Li, Shenao (State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University) Zhao, Shumiao (State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University) Peng, Nan (State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University) Liang, Yunxiang (State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University) |
1 | van Orsouw, N., D. Li, and J. Vijg. 1997. Denaturing gradient gel electrophoresis (DGGE) increases resolution and informativity of Alu-directed inter-repeat PCR. Mol. Cell. Probes 11:95-101. DOI ScienceOn |
2 | Vanhoutte, T., V. De Preter, E. De Brandt, K. Verbeke, J. Swings, and G. Huys. 2006. Molecular monitoring of the fecal microbiota of healthy human subjects during administration of lactulose and Saccharomyces boulardii. Appl. Environ. Microbiol. 72: 5990-5997. DOI ScienceOn |
3 | Vondruskova, H., R. Slamova, M. Trckova, Z. Zraly, and I. Pavlik. 2010. Alternatives to antibiotic growth promoters in prevention of diarrhoea in weaned piglets: A review. Vet. Med-Czech. 55: 199-224. |
4 | Walter, J., G. W. Tannock, A. Tilsala-Timisjarvi, S. Rodtong, D. M. Loach, K. Munro, and T. Alatossava. 2000. Detection and identification of gastrointestinal Lactobacillus species by using denaturing gradient gel electrophoresis and species-specific PCR primers. Appl. Environ. Microbiol. 66:297-303. DOI ScienceOn |
5 | Wang, S. P., L. Yang, X. S. Tang, L. C. Cai, G. Liu, X. F. Kong, F. Blachier, and Y. L. Yin. 2011. Dietary supplementation with high-dose Bacillus subtilis or Lactobacillus reuteri modulates cellular and humoral immunities and improves performance in weaned piglets. J. Food Agric. Environ. 9:181-187. |
6 | Willis, W. and L. Reid. 2008. Investigating the effects of dietary probiotic feeding regimens on broiler chicken production and Campylobacter jejuni presence. Poult. Sci. 87:606-611. DOI ScienceOn |
7 |
Zhang, Z. F., T. X. Zhou, X. Ao, and I. H. Kim. 2012. Effects of |
8 | Sen, S., S. L. Ingale, J. S. Kim, K. H. Kim, Y. W. Kim, C. Khong, J. D. Lohakare, E. K. Kim, H. S. Kim, I. K. Kwon, and B. J. Chae. 2011. Effect of supplementation of Bacillus subtilis LS 1-2 grown on citrus-juice waste and corn-soybean meal substrate on growth performance, nutrient retention, caecal microbiology and small intestinal morphology of broilers. Asian Australas. J. Anim. Sci. 24:1120-1127. 과학기술학회마을 DOI ScienceOn |
9 | Sindhu, S. C. and N. Khetarpaul. 2003. Effect of feeding probiotic fermented indigenous food mixture on serum cholesterol levels in mice. Nutr. Res. 23:1071-1080. DOI ScienceOn |
10 | Smillie, C. S., M. B. Smith, J. Friedman, O. X. Cordero, L. A. David, and E. J. Alm. 2011. Ecology drives a global network of gene exchange connecting the human microbiome. Nature 480:241-244. DOI ScienceOn |
11 | Sokol, H., B. Pigneur, L. Watterlot, O. Lakhdari, L. G. Bermudez- Humaran, J.-J. Gratadoux, S. Blugeon, C. Bridonneau, J.-P. Furet, and G. Corthier et al. 2008. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc. Natl. Acad. Sci. USA. 105:16731-16736. DOI ScienceOn |
12 | Srinivasan, S., A. Aslan, I. Xagoraraki, E. Alocilja, and J. B. Rose. 2011. Escherichia coli, Enterococci, and Bacteroides thetaiotaomicron qPCR signals through wastewater and septage treatment. Water Res. 45: 2561-2572. DOI ScienceOn |
13 | Taras, D., W. Vahjen, M. Macha, and O. Simon. 2005. Response of performance characteristics and fecal consistency to longlasting dietary supplementation with the probiotic strain Bacillus cereus var. toyoi to sows and piglets. Arch. Anim. Nutr. 59:405-417. DOI ScienceOn |
14 | Taras, D., W. Vahjen, and O. Simon. 2007. Probiotics in pigs - modulation of their intestinal distribution and of their impact on health and performance. Livest. Sci. 108:229-231. DOI ScienceOn |
15 | Pryde, S. E., S. H. Duncan, G. L. Hold, C. S. Stewart, and H. J. Flint. 2002. The microbiology of butyrate formation in the human colon. FEMS Microbiol. Lett. 217:133-139. DOI |
16 | NRC. 1998. Nutrient Requirements of Swine. 10th ed. National Academies Press, Washington, DC, USA. |
17 | Petersson, A., K. J. Domig, P. Nagel, W. Zollitsch, W. Hagmuller, and W. Kneifel. 2009. Denaturing gradient gel electrophoresis (DGGE)-based monitoring of intestinal Lactobacilli and Bifidobacteria of pigs during a feeding trial. Arch. Anim. Nutr. 63:112-126. DOI ScienceOn |
18 | Pieper, R., P. Janczyk, V. Urubschurov, U. Korn, B. Pieper, and W. B. Souffrant. 2009. Effect of a single oral administration of Lactobacillus plantarum DSMZ 8862/8866 before and at the time point of weaning on intestinal microbial communities in piglets. Int. J. Food Microbiol. 130:227-232. DOI ScienceOn |
19 | Sen, S., S. L. Ingale, Y. W. Kim, J. S. Kim, K. H. Kim, J. D. Lohakare, E. K. Kim, H. S. Kim, M. H. Ryu, I. K. Kwon, and B. J. Chae. 2012. Effect of supplementation of Bacillus subtilis LS 1-2 to broiler diets on growth performance, nutrient retention, caecal microbiology and small intestinal morphology. Res. Vet. Sci. 93: 264-268. DOI ScienceOn |
20 | Madden, U. A., G. D. Osweiler, L. Knipe, G. W. Beran, and D. C. Beitz. 1999. Effects of Eubacterium coprostanoligenes and Lactobacillus on pH, lipid content, and cholesterol of fermented pork and mutton sausage-type mixes. J. Food Sci. 64:903-908. DOI ScienceOn |
21 | McCann, K. S. 2000. The diversity-stability debate. Nature 405: 228-233. DOI ScienceOn |
22 | Nakano, M. M. and P. Zuber. 1998. Anaerobic growth of a "strict aerobe" (Bacillus subtilis). Annu. Rev. Microbiol. 52:165-190. DOI ScienceOn |
23 | Lopez-Siles, M., T. M. Khan, S. H. Duncan, H. J. M. Harmsen, L. J. Garcia-Gil, and H. J. Flint. 2012. Cultured representatives of two major phylogroups of human colonic Faecalibacterium prausnitzii can utilize pectin, uronic acids, and host-derived substrates for growth. Appl. Environ. Microbiol. 78:420-428. DOI |
24 | Lee, D. H., Y. G. Zo, and S. J. Kim. 1996. Nonradioactive method to study genetic profiles of natural bacterial communities by PCR-single-strand-conformation polymorphism. Appl. Environ. Microbiol. 62:3112-3120. |
25 | Lee, K. W., S. H. Lee, H. S. Lillehoj, G. X. Li, S. I. Jang, U. S. Babu, M. S. Park, D. K. Kim, E. P. Lillehoj, A. P. Neumann, T. G. Rehberger, and G. R. Siragusa. 2010. Effects of direct-fed microbials on growth performance, gut morphometry, and immune characteristics in broiler chickens. Poult. Sci. 89:203-216. DOI ScienceOn |
26 | Lee, S. H., S. L. Ingale, J. S. Kim, K. H. Kim, A. Lokhande, E. K. Kim, I. K. Kwon, Y. H. Kim, and B. J. Chae. 2014. Effects of dietary supplementation with Bacillus subtilis LS 1-2 fermentation biomass on growth performance, nutrient digestibility, cecal microbiota and intestinal morphology of weanling pig. Anim. Feed Sci. Technol. 188:102-110. DOI ScienceOn |
27 |
Li, M., J. Gong, M. Cottrill, H. Yu, C. de Lange, J. Burton, and E. Topp. 2003. Evaluation of |
28 | Li, Z., G. Yi, J. Yin, P. Sun, D. Li, and C. Knight. 2008. Effects of organic acids on growth performance, gastrointestinal pH, intestinal microbial populations and immune responses of weaned pigs. Asian Australas. J. Anim. Sci. 21:252-261. 과학기술학회마을 DOI |
29 | Fu, C. J., J. N. Carter, Y. Li, J. H. Porter, and M. S. Kerley. 2006. Comparison of agar plate and real-time PCR on enumeration of Lactobacillus, Clostridium perfringens and total anaerobic bacteria in dog faeces. Lett. Appl. Microbiol. 42:490-494. DOI ScienceOn |
30 | Giang, H. H., T. Q. Viet, B. Ogle, and J. E. Lindberg. 2012. Growth performance, digestibility, gut environment and health status in weaned piglets fed a diet supplemented with a complex of lactic acid bacteria alone or in combination with Bacillus subtilis and Saccharomyces boulardii. Livest. Sci. 143:132-141. DOI ScienceOn |
31 | Hong, H. A., L. H. Duc, and S. M. Cutting. 2005. The use of bacterial spore formers as probiotics. FEMS Microbiol. Rev. 29:813-835. DOI ScienceOn |
32 | Gong, J., H. Yu, T. Liu, M. Li, W. Si, C. F. M. De lange, and C. Dewey. 2008. Characterization of ileal bacterial microbiota in newly-weaned pigs in response to feeding lincomycin, organic acids or herbal extract. Livest. Sci. 116:318-322. DOI ScienceOn |
33 | Han, K. S., P. Balan, F. Molist Gasa, and M. Boland. 2011. Green kiwifruit modulates the colonic microbiota in growing pigs. Lett. Appl. Microbiol. 52:379-385. DOI ScienceOn |
34 | Han, W., X. L. Zhang, D. W. Wang, L. Y. Li, G. L. Liu, A. K. Li, and Y. X. Zhao. 2013. Effects of microencapsulated Enterococcus fecalis CG1.0007 on growth performance, antioxidation activity, and intestinal microbiota in broiler chickens. J. Anim. Sci. 91:4374-4382. DOI ScienceOn |
35 | Hu, Y., X. Yang, J. Qin, N. Lu, G. Cheng, N. Wu, Y. Pan, J. Li, L. Zhu, and X. Wang et. al. 2013. Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Natr. Commun. 4. Article number 2151. |
36 | Jones, S. E. and K. L. Knight. 2012. Bacillus subtilis-mediated protection from Citrobacter rodentium-associated enteric disease requires esph and functional flagella. Infect. Immun. 80:710-719. DOI |
37 | Kim, Y. I., Y. H. Lee, K. H. Kim, Y. K. Oh, Y. H. Moon, and W. S. Kwak. 2012. Effects of supplementing microbially-fermented spent mushroom substrates on growth performance and carcass characteristics of Hanwoo steers (a field study). Asian Australas. J. Anim. Sci. 25:1575-1581. 과학기술학회마을 DOI ScienceOn |
38 | ben Omar, N. and F. Ampe. 2000. Microbial community dynamics during production of the Mexican fermented maize dough pozol. Appl. Environ. Microbiol. 66:3664-3673. DOI ScienceOn |
39 | Alexopoulos, C., I. E. Georgoulakis, A. Tzivara, S. K. Kritas, A. Siochu, and S. C. Kyriakis. 2004. Field evaluation of the efficacy of a probiotic containing Bacillus licheniformis and Bacillus subtilis spores, on the health status and performance of sows and their litters. J. Anim. Physiol. Anim. Nutr. 88: 381-392. DOI ScienceOn |
40 | Aliakbarpour, H. R., M. Chamani, G. Rahimi, A. A. Sadeghi, and D. Qujeq. 2012. The Bacillus subtilis and lactic acid bacteria probiotics influences intestinal mucin gene expression, histomorphology and growth performance in broilers. Asian Australas. J. Anim. Sci. 25:1285-1293. 과학기술학회마을 DOI ScienceOn |
41 | Chen, W., X. Z. Zhu, J. P. Wang, Z. X. Wang, and Y. Q. Huang. 2013. Effects of Bacillus subtilis var. natto and Saccharomyces cerevisiae fermented liquid feed on growth performance, relative organ weight, intestinal microflora, and organ antioxidant status in Landes geese. J. Anim. Sci. 91:978-985. DOI ScienceOn |
42 | Cui, C., C. J. Shen, G. Jia, and K. N. Wang. 2013. Effect of dietary Bacillus subtilis on proportion of Bacteroidetes and Firmicutes in swine intestine and lipid metabolism. Genet. Mol. Res. 12: 1766-1776. DOI ScienceOn |
43 | Eckburg, P. B., E. M. Bik, C. N. Bernstein, E. Purdom, L. Dethlefsen, M. Sargent, S. R. Gill, K. E. Nelson, and D. A. Relman. 2005. Diversity of the human intestinal microbial flora. Science 308:1635-1638. DOI ScienceOn |
44 | Zoetendal, E. G., A. D. L. Akkermans, and W. M. De Vos. 1998. Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl. Environ. Microbiol. 64: 3854-3859. |
45 | Ricca, D. M., C. J. Ziemer, and B. J. Kerr. 2010. Changes in bacterial communities from swine feces during continuous culture with starch. Anaerobe 16:516-521. DOI ScienceOn |
46 | Konstantinov, S. R., A. A. Awati, B. A. Williams, B. G. Miller, P. Jones, C. R. Stokes, A. D. L. Akkermans, H. Smidt, and W. M. De Vos. 2006. Post-natal development of the porcine microbiota composition and activities. Environ. Microbiol. 8: 1191-1199. DOI ScienceOn |
47 | Tsukahara, T., T. Tsuruta, N. Nakanishi, C. Hikita, M. Mochizuki, and K. Nakayama. 2013. The preventive effect of Bacillus subtilus strain DB9011 against experimental infection with enterotoxcemic Escherichia coli in weaning piglets. Anim. Sci. J. 84:316-321. DOI ScienceOn |
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