Effects of Acanthopanax senticosus Polysaccharide Supplementation on Growth Performance, Immunity, Blood Parameters and Expression of Pro-inflammatory Cytokines Genes in Challenged Weaned Piglets |
Han, Jie
(College of Animal Science and Veterinary Science, Shenyang Agricultural University)
Bian, Lianquan (College of Animal Science and Veterinary Science, Shenyang Agricultural University) Liu, Xianjun (College of Animal Science and Veterinary Science, Shenyang Agricultural University) Zhang, Fei (College of Animal Science and Veterinary Science, Shenyang Agricultural University) Zhang, Yiran (College of Animal Science and Veterinary Science, Shenyang Agricultural University) Yu, Ning (Liaoning Academy of Agricultural Sciences) |
1 | Richards, C., J. Gauldie, and H. Baumann. 1991. Cytokine control of acute phase protein expression. Eur. Cytokine Netw. 2 89-98. |
2 | Shen, M. L., S. K. Zhai, H. L. Chen, Y. D. Luo, G. R. Tu, and D. W. Ou. 1991. Immunomopharmacological effects of polysaccharides from Acanthopanax senticosus on experimental animals. Int. J. Immunopharmacol. 13:549-554. DOI ScienceOn |
3 | Soto, L., A. I. Martin, S. Millan, E. Vara, and A. Lopez-Calderon. 1998. Effects of endotoxin lipopolysaccharide administration on the somatotropic axis. J. Endocrinol. 159:239-246. DOI ScienceOn |
4 | Spurlock, M. E. 1997. Regulation of metabolism and growth during immune challenge: An overview of cytokine function. J. Anim. Sci. 75:1773-1783. |
5 | Le Floc'h, N. L., D. Melchior, and C. Obled. 2004. Modifications of protein and amino acid metabolism during inflammation and immune system activation. Livest. Prod. Sci. 87:37-45. DOI ScienceOn |
6 | Li, L. L., X. Wu, H. Z. Peng, M. Z. Fan, Z. P. Hou, X. F. Kong, Y. L. Yin, B. Zhang, T. J. Li, Y. Q. Hou, K. M .Yang, A. K. Li, C. Y. Liu, X. M. Qiu, and Y. L. Liu. 2009. The effect of dietary addition of a polysaccharide from Atractylodes macrophala Koidz on growth performance, immunoglobulin concentration and IL- expression in weaned piglets. J. Agric. Sci. 147: 625-631. DOI ScienceOn |
7 | Chen, R. Z., Z. Q. Liu, J. M. Zhao, R. P. Chen, F. L. Meng, M. Zhang, and W. C. Ge. 2011. Antioxidant and immunobiological activity of water-soluble polysaccharide fractions purified from Acanthopanax senticosus. Food Chem. 127:434-440. DOI ScienceOn |
8 | Deyama, T., S. Nishibe, and Y. Nakazawa. 2001. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta. Pharmacol. Sin. 22:1057-1070. |
9 | Blecha, F. and B. Charley. 1990. Rationale for using immunpotentiators in domestic food animals. In Immunomodulation in Domestic Food Animals (Ed. F. Blecha and B. Charley). Academic Press, San Diego, CA. pp. 3-19. |
10 | Zhang, L. P., L. Y. Chen, and Y. S. Zhang. 1993. Study on water soluble polysaccharides from Acanthopanax senticosus fruits isolation and purification and structural investigating of AS-2. Chin. J. Biochem. Mol. Biol. 9:1-5. |
11 | Ling, P. R., B. R. Bistrian, B. Mendez, and N. W. Istfan. 1994. Effects of systemic infusions of endotoxin, tumor necrosis factor, and interleukin-1 on glucose metabolism in the rat: Relationship to endogenous glucose production and peripheral tissue glucose uptake. Metabolism 43:279-284. DOI ScienceOn |
12 | Livak, K. J. and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the method. Methods 25:402-408. DOI ScienceOn |
13 | McGlone, J. J., J. L. Salak, E. A. Lumpkin, R. I. Nicholson, M. Gibson, and R. L. Norman. 1983. Shipping stress and social status effects on pig performance, plasma cortisol, natural killer cell activity, and leukocyte numbers. J. Anim. Sci. 71: 888-896. |
14 | Memon, R. A., K. R. Feingold, and C. Grunfeld. 1994. The effects of cytokines on intermediary metabolism. Endocrinologist 4: 59-63. |
15 | Medzhitov, R. and C. Janeway. 2000. Innate immune recognition:mechanisms and pathways. Immunol. Rev. 173: 89-97. DOI ScienceOn |
16 | Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Method 65:55-63. DOI ScienceOn |
17 | NRC. 1998. Nutrient Requirements of Swine. 10th ed. National Academy Press, Washington, DC. |
18 | Touchette, K. J., J. A. Carroll, G. L. Allee, R. L. Matteri, C. J. Dyer, L. A. Beausang and M. E. Zannelli. 2002. Effect of spray-dried plasma and lipopolysaccharide exposure on weaned pigs: I. Effects on the immune axis of weaned pigs. J. Anim. Sci. 80: 494-501. |
19 | Park, E. J., J. X. Nan, Y. Z. Zhao, S. H. Lee, Y. H. Kim, J. B. Nam, J. J. Lee, and D. H. Sohn. 2004. Water-soluble polysaccharide from Eleutherococcus senticosus stems attenuates fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice. Basic Clin. Pharmacol. Toxicol. 94:298-304. |
20 | Staub, A. M. 1965. Removal of protein-sevag method. In: Methods in Carbohydrate Chemistry (ED. R. L. Whistler). Academic Press, New York, USA. |
21 | Wagner, H., A. Proksch, I. Riess-Maurer, A. Vollmar, S. Odenthal, H. Stuppner, K. Jurcic, T. M. Le, and J. N. Fang. 1985. Immunostimulating action of polysaccharides (heteroglycans) from higher plants. Arzneimittelforschung 35:1069-1075. |
22 | Webel, D. M., B. N. Finck, D. H. Baker, and R. W. Johnson. 1997. Time course of increased plasma cytokines, cortisol, and urea nitrogen in pigs following intraperitoneal injection of lipopolysaccharide. J. Anim. Sci. 75:1514-1520. |
23 | Wright, K. J., R. Balaji, C. M. Hill, S. S. Dritz, E. L. Knoppel, and J. E. Minton. 2000. Integrated adrenal, somatotropic, and immune responses of growing pigs to treatment with lipopolysaccharide. J. Anim. Sci. 78:1892-1899. |
24 | Wu, X., F. Y. Yan, X. F. Kong, T. J. Li, R. L. Huang, L. X. Chen, and Y. L. Yin. 2010. Effects of Acanthopanax senticosus extract on growth performance and anti-oxidative capacity in weaned piglet. Nat. Prod. Res. Dev. 22:297-301. |
25 | Kong, X. F., Y. Z. Zhang, Y. L. Yin, G. Y. Wu, H. J. Zhou, Z. L. Tan, F. Yang, M. J. Bo, R. L. Huang, T. J. Li, and M. M. Geng. 2009b. Chinese Yam polysaccharide enhances growth performance and cellular immune response in weanling rats. J. Sci. Food Agric. 89:2039-2044. DOI ScienceOn |
26 | Yin, F. G., Y. L. Yin, X. F. Kong, Y. L. Liu, Q. H. He, T. J. Li, R. L. Huang, Y. Q. Hou, X. G. Shu, L. X. Tan, L. X. Chen, J. H. Gong, S. W. Kim, and G. Y. Wu. 2008. Dietary supplementation with Acanthopanax senticosus extract modulates gut microflora in weaned piglets. Asian Australas. J. Anim. Sci. 21:1330-1338. 과학기술학회마을 DOI |
27 | Steinmann, G. G., A. Esperester, and P. Joller. 2001. Immunopharmacological in vitro effects of Eleutheroeoceus senticosus extracts. Arzneimittelforschung 5l:76-83. |
28 | Kong, X. F., Y. L. Yin, Q. H. He, F. G. Yin, H. J. Liu, T. J. Li, R. L. Huang, M. M. Geng, Z. Ruan, Z. Y. Deng, M. Y. Xie, and G. Wu. 2008. Dietary supplementation with Chinese herbal powder enhances ileal digestibilities and serum concentrations of amino acids in young pigs. Amino Acids. 37:573-582. |
29 | Kong, X. F., G. Y. Wu, Y. P. Liao, Z. P. Hou, H. J. Liu, F. G. Yin, T. J. Li, R. L. Huang, Y. M. Zhang, D. Deng, P. Kang, R. X. Wang, Z. Y. Tang, C. B. Yang, Z. Y. Deng, H. Xiong, W. Y. Chu, Z. Ruan, M. Y. Xie, and Y. L. Yin. 2007b. Effects of Chinese herbal ultra-fine powder as a dietary additive on growth performance, serum metabolites and intestinal health in early-weaned piglets. Livest. Sci. 108:272-275. DOI ScienceOn |
30 | Kong, X. F., F. G. Yin, Q. H. He, H. J. Liu, T. J. Li, R. L. Huang, M. Z. Fan, Y. L. Liu, Y. Q. Hou, P. Li, Z. Ruan, Z. Y. Deng, M. Y. Xie, H. Xiong, and Y. L. Yin. 2009a. Acanthopanax senticosus extract as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets. Livest. Sci. 123:261-267. DOI ScienceOn |
31 | Lai, C. H., J. D. Yin, D. F. Li, L. D. Zhao, S. Y. Qiao, and J. J. Xing. 2005. Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide. J. Nutr. 135:239-244. |
32 | Lang, C. H., C. Dobrescu, and G. J. Bagby. 1992. Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology 130:43-52. |
33 | Han, S. B., Y. D. Yoon, H. J. Ahn, H. S. Lee, C. W. Lee, W. K. Yoon, S. K. Park, and H. M. Kim. 2003. Toll-like receptormediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus. Int. lmmunopharmacol. 3:1301-1312. DOI ScienceOn |
34 | Kelley, K. W., R. W. Johnson, and R. Dantzer. 1994. Immunology discovers physiology. Vet. Immunol. Immunopathol. 43:157-165. DOI ScienceOn |
35 | Hevener, W., G. W. Almond, J. D. Armstrong, and R. G. Richards. 1997. Effects of acute endotoxemia on serum somatotropin and insulin-like growth factor I concentrations in prepubertal gilts. Am. J. Vet. Res. 58:1010-1013. |
36 | Johnson, R. W. and E. Von Borell. 1994. Lipopolysaccharideinduced sickness behavior in pigs is inhibited by pretreatment with indomethacin. J. Anim. Sci. 72:309-314. |
37 | Johnson, R. W. 1997. Inhibition of growth by pro-inflammatory cytokines: an integrated view. J. Anim. Sci. 75:1244-1255. |
38 | Klasing, K. C. and B. J. Johnstone. 1991. Monokines in growth and development. Poult. Sci. 70:1781-1789. DOI ScienceOn |
39 | Klasing, K. C. 1988. Nutritional aspects of leukocytic cytokines. J. Nutr. 118:1436-1446. |
40 | Klasing, K. C., D. E. Laurin, R. K. Peng, and D. M. Fry. 1987. Immunologically mediated growth depression in chicks: Influence of feed intake, corticosterone and interleukin-1. J. Nutr. 117:1629-1637. |
41 | Kong, X. F., Y. L.Yin, G. Y. Wu, H. J. Liu, F. G. Yin, T. J. Li, R. L. Huang, Z. Ruan, H. Xiong, Z. Y. Deng, M. Y. Xie, Y. P. Liao, and S. W. Kim. 2007a. Dietary supplementation with Acanthopanax senticosus extract modulates cellular and humoral immunity in weaned piglets. Asian Australas. J. Anim. Sci. 20:1453-1461. 과학기술학회마을 DOI |
42 | Chen, H. L., D. F. Li, B. Y. Chang, L. M. Gong, J. G. Dai, and G. F. Yi. 2003. Effects of Chinese herbal polysaccharides on the immunity and growth performance of young broilers. Poult. Sci. 82:364-370. DOI |
43 | Fang, J., F. Y. Yan, X. F. Kong, Z. Ruan, Z. Q. Liu, R. L. Huang, T. J. Li, M. M. Geng, F. Yang, Y. Z. Zhang, P. Li, Joshua Gong, G. Y. Wu, M. Z. Fan, Y. L. Liu, Y. Q. Hou, and Y. L. Yin. 2009. Dietary supplementation with Acanthopanax senticosus extract enhances gut health in weanling piglets. Livest. Sci. 123:268-275. DOI ScienceOn |
44 | DuBois, M., K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith. 1956. Colorimetric method for determination of sugars and related substances. Anal. Chem. 28:350-356. DOI |
45 | Elsasser, T. H., T. S. Rumsey, A. C. Hammond, and R. Fayer. 1988. Influence of parasitism on plasma concentrations of growth hormone, somatomedin-C, and somatomedin binding proteins in calves. J. Endocrinol. 116:191-200. DOI ScienceOn |
46 | Fan, J., M. M. Wojnar, M. Theodorakis, and C. H. Lang. 1996. Regulation of insulin-like growth factor (IGF)-I mRNA and peptide and IGF-binding proteins by interleukin-1. Am. J. Physiol. 270:R621-R629. |
47 | Guo, G. L., Y. L. Liu, W. Fan, J. Han, Y. Q. Hou, Y. L. Yin, H. L. Zhu, B. Y. Ding, J. X. Shi, J. L. Lu, H. R. Wang, J. Chao, and Y. H. Qu. 2008. Effects of Achyranthes Bidentata polysaccharide on growth performance, immunological, adrenal, and somatotropic responses of weaned pigs challenged with Escherichia coli lipopolysaccharide. Asian Australas. J. Anim. Sci. 21:1189-1195. 과학기술학회마을 DOI |
48 | Han, J., L. Q. Bian, X. J. Liu, F. Zhang, and K. K. Yang. 2012a. Effects of dietary Acanthopanax senticosus polysaccharide on growth performance and immune parameters of weaner piglets. Chin. J. Anim. Nutr. 24: 2203-2209. |
49 | Han, J., L. Q. Bian, X. J. Liu, F. Zhang, and K. K. Yang. 2012b. Effects of dietary Acanthopanax senticosus polysaccharide on immune parameters in blood of weaner piglets. Chin. J. Anim. Nutr. 24:2444-2449. |
50 | Yuan, S. L., X. S. Piao, D. F. Li, S. W. Kim, H. S. Lee, and P. F. Guo. 2006. Effects of dietary Astragalus polysaccharide on growth performance and immune function in weaned pigs. Anim. Sci. 82:501-507. |