• Title/Summary/Keyword: pig bone

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Experimental Evaluation of a Surgical Robot System (ARTHROBOT) for Hip Surgery using Sawbones and Pig Femurs

  • Ko, Seong-Young;Kim, Jonathan;Chung, Jong-Ha;Kwon, Dong-Soo;Lee, Jung-Ju;Yoon, Yong-San;Won, Chung-Hee
    • 제어로봇시스템학회:학술대회논문집
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    • 2002.10a
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    • pp.119.3-119
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    • 2002
  • $\textbullet$ A bone-mountable surgical robot system for hip surgery $\textbullet$ A simple gauge-based registration method $\textbullet$ A proposed surgical procedure $\textbullet$ Evaluation method for position/orientation accuracy $\textbullet$ Evaluation method for surface conformity $\textbullet$ The performance evaluation of ARTHROBOT $\textbullet$ Summary

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Identification of genes related to intramuscular fat content of pigs using genome-wide association study

  • Won, Sohyoung;Jung, Jaehoon;Park, Eungwoo;Kim, Heebal
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.2
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    • pp.157-162
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    • 2018
  • Objective: The aim of this study is to identify single nucleotide polymorphisms (SNPs) and genes related to pig IMF and estimate the heritability of intramuscular fat content (IMF). Methods: Genome-wide association study (GWAS) on 704 inbred Berkshires was performed for IMF. To consider the inbreeding among samples, associations of the SNPs with IMF were tested as random effects in a mixed linear model using the genetic relationship matrix by GEMMA. Significant genes were compared with reported pig IMF quantitative trait loci (QTL) regions and functional classification of the identified genes were also performed. Heritability of IMF was estimated by GCTA tool. Results: Total 365 SNPs were found to be significant from a cutoff of p-value <0.01 and the 365 significant SNPs were annotated across 120 genes. Twenty five genes were on pig IMF QTL regions. Bone morphogenetic protein-binding endothelial cell precursor-derived regulator, forkhead box protein O1, ectodysplasin A receptor, ring finger protein 149, cluster of differentiation, tyrosine-protein phosphatase non-receptor type 1, SRY (sex determining region Y)-box 9 (SOX9), MYC proto-oncogene, and macrophage migration inhibitory factor were related to mitogen-activated protein kinase pathway, which regulates the differentiation to adipocytes. These genes and the genes mapped on QTLs could be the candidate genes affecting IMF. Heritability of IMF was estimated as 0.52, which was relatively high, suggesting that a considerable portion of the total variance of IMF is explained by the SNP information. Conclusion: Our results can contribute to breeding pigs with better IMF and therefore, producing pork with better sensory qualities.

Effect of Metals used in Orthopedic on Magnetic Resonance Imaging II (정형 보철용 금속이 자기공명영상에 미치는 영향 II)

  • Kim, Hyeong-Gyun;Choi, Seong-Dae
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.11 no.5
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    • pp.115-120
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    • 2012
  • Metals used orthopedic in human magnetic resonance imaging scan of the metal to be inserted, The information to users about the image distortion is to propose a basis for judgment. Metals used orthopedic on Stainless, Titanium and Clip using ferromagnetic artifacts and distortion of the image were measured. Using Phantom "Effect of Metals used in Orthopedic on Magnetic Resonance ImagingI" pig in a paper subsequently was carried out using the same bone. Experimental results using a pure Titanium is a relatively high diagnostic value was found that.

Treatment of Palatogingival Groove using Glass-Ionomer cement and Emdogain$^{(R)}$ (Original Article 2 - 글라스-아이오노머 시멘트와 Emdogain$^{(R)}$을 이용한 구개치은발육구의 치료)

  • Jin, Myoung-Uk
    • The Journal of the Korean dental association
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    • v.48 no.1
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    • pp.56-62
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    • 2010
  • In recent years, a number of special treatment procedures have been introduced to reestablish new tooth supporting tissues with varying degrees of success including guided tissue regeneration(GTR), bone grafting(BG) and the use of enamel matrix derivative(EMD). EMD is an extract of enamel matrix and contains amelogenins of various molecular weights. Emdogain(EMD) might have some advantages over other methods of regenerating the tissue supporting teeth lost by gum disease, such as less postoperative complications. Emdogain contains proteins(derived from developing pig teeth) believed to regenerate tooth attachment. The decrease in probing depth after EMD treatment is achieved primarily by clinical attachment gain and bone regeneration and only to a minor extent by gingival recession. In conclsion, EMD seems to be safe, was able to regenerate lost periodontal tissues in previously diseased sites based on clinical parameters.

The Use of Special Washers in Bone Plates for Improved Impact-Absorbing Characteristics (충격흡수 특성의 향상을 위하 내고정용 특수 와셔에 관한 연구)

  • 김윤영;김장수
    • Journal of Biomedical Engineering Research
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    • v.16 no.4
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    • pp.457-462
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    • 1995
  • Unlike the usual bone plate and screw fracture fixation, an improved plate fixation method, which can transfer gradually physiological load to bones, is described. The key feature of the present method is to use washers between the plate and the screw. Bio-absorbable materials or non-ferrous materials with good damping characteristics are used to manufacture the washers. The purpose of this paper is to discuss potential advantages of the proposed method, and to show experimentally its improved impact-absorbing characteristics. Vibration experiments are carried out for pig femurs and cow tibias with and without the proposed washers. This experiments show that the washers can drop the first peak value suite substantially in the FRF plots. Although in-vivo experiments have not been conducted, the present fixation method appears to be a simple and effective alternative to the presently used method.

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Effects of Benzoic Acid and Dietary Calcium:Phosphorus Ratio on Performance and Mineral Metabolism of Weanling Pigs

  • Gutzwiller, A.;Schlegel, P.;Guggisberg, D.;Stoll, P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.4
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    • pp.530-536
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    • 2014
  • In a $2{\times}2$ factorial experiment the hypotheses tested were that the metabolic acid load caused by benzoic acid (BA) added to the feed affects bone mineralization of weanling pigs, and that a wide dietary calcium (Ca) to phosphorus (P) ratio in phytase-supplemented feeds with a marginal P concentration has a positive effect on bone mineralization. The four experimental diets, which contained 0.4% P and were supplemented with 1,000 FTU phytase/kg, contained either 5 g BA/kg or no BA and either 0.77% Ca or 0.57% Ca. The 68 four-week-old Large White pigs were fed the experimental diets ad libitum for six weeks and were then slaughtered. Benzoic acid increased feed intake (p = 0.009) and growth rate (p = 0.051), but did not influence the feed conversion ratio (p>0.10). Benzoic acid decreased the pH of the urine (p = 0.031), but did not affect breaking strength and mineralization of the tibia (p>0.10). The wide Ca:P ratio decreased feed intake (p = 0.034) and growth rate (p = 0.007) and impaired feed the conversion ratio (p = 0.027), but increased the mineral concentration in the fat-free DM of the tibia (p = 0.013) without influencing its breaking strength (p>0.10). The observed positive effect of the wide Ca:P ratio on bone mineralization may be attributed, at least in part, to the impaired feed conversion ratio, i.e. to the higher feed intake and consequently to the higher mineral intake per kg BW gain. The negative impact on animal performance of the wide dietary Ca:P ratio outweighs its potentially positive effect on bone mineralization, precluding its implementation under practical feeding conditions.

Effects of Graded Levels of Montmorillonite on Performance, Hematological Parameters and Bone Mineralization in Weaned Pigs

  • Duan, Q.W.;Li, J.T.;Gong, L.M.;Wu, H.;Zhang, L.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.11
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    • pp.1614-1621
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    • 2013
  • The aim of this study was to investigate the effects of graded levels of montmorillonite, a constituent of clay, on performance, hematological parameters and bone mineralization in weaned pigs. One hundred and twenty, 35-d-old crossbred pigs (Duroc${\times}$Large White${\times}$Landrace, $10.50{\pm}1.20$ kg) were used in a 28-d experiment and fed either an unsupplemented corn-soybean meal basal diet or similar diets supplemented with 0.5, 1.0, 2.5 or 5.0% montmorillonite added at the expense of wheat bran. Each treatment was replicated six times with four pigs (two barrows and two gilts) per replicate. Feed intake declined (linear and quadratic effect, p<0.01) with increasing level of montmorillonite while feed conversion was improved (linear and quadratic effect, p<0.01). Daily gain was unaffected by dietary treatment. Plasma myeloperoxidase declined linearly (p = 0.03) with increasing dietary level of montmorillonite. Plasma malondialdehyde and nitric oxide levels were quadratically affected (p<0.01) by montmorillonite with increases observed for pigs fed the 0.5 and 1.0% levels which then declined for pigs fed the 2.5 and 5.0% treatments. In bone, the content of potassium, sodium, copper, iron, manganese and magnesium were decreased (linear and quadratic effect, p<0.01) in response to an increase of dietary montmorillonite. These results suggest that dietary inclusion of montmorillonite at levels as high as 5.0% does not result in overt toxicity but could induce potential oxidative damage and reduce bone mineralization in pigs.

Comparison of Primary Stability of Different Femoral Fixation Techniques in Anterior Cruciate Ligament Reconstruction (전 십자 인대 재건술에서 대퇴골측 고정 방법의 초기 안정성의 비교)

  • Song, Eun-Kyoo;Lee, Keun-Bae;Lee, Moon
    • Journal of the Korean Arthroscopy Society
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    • v.2 no.1
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    • pp.85-92
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    • 1998
  • Various methods for fixation of graft have been widely used for reconstruction of anterior cruciate ligament. However, the biomechanical strength of each fixation techniques are not fully understood. The purpose of this study is to compare the pull out strength of different fixation techniques which is probably the most important factor for the success at the initial stage of healing. Biomechanical test was carried out to measure and compare the pull out tensile strength of five different fixation techniques in 35 pig(Yorkshire) knees. ANOVA and Duncan multiple comparison test was applied for statistical analysis. In the two fixation techniques with bone patellar tendon bone graft, the mean maximum tensile strength was $1333.4{\pm}148.5N$ with titanium interference screw, while it was $1310.1{\pm}168.9N$ with biodegradable interference screw. The failure mode were pulled out of bone plugs from the femoral tunnel in majority cases. In the fixations with hamstring tendon, the mean maximum tensile strength were $1405.9{\pm}135.1N$ with SemiFix screw, $820.3{\pm}104.5N$ with biodegradable interference screw, and $682.1{\pm}54.2N$ with Endobutton. The mode of failure was variable in each technique. The tendon was pulled out from the tunnel in biodegradable interference screw fixation, the screw was bent in the SemiFix system, and the polyester tape were ruptured or the buttons were pulled into tunnel in Endobutton fixation. The mean maximum tensile strength of two interference screws with bone patellar tendon bone was statistically comparable to that of SemiFix with hamstring tendon. However biodegradable interference screw and Endobutton with hamstring tendon showed weaker maximum tensile strength than above three fixation techniques (P<0.05).

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A comparison of bone bed preparation with laser and conventional drill on the relationship between implant stability quotient (ISQ) values and implant insertion variables

  • Lee, Su-Young;Piao, Chunmei;Heo, Seong-Joo;Koak, Jai-Young;Lee, Joo-Hee;Kim, Tae-Hyung;Kim, Myung-Joo;Kwon, Ho-Beom;Kim, Seong-Kyun
    • The Journal of Advanced Prosthodontics
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    • v.2 no.4
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    • pp.148-153
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    • 2010
  • PURPOSE. The aim of this study was to investigate a comparison of implant bone bed preparation with Er,Cr:YSGG laser and conventional drills on the relationship between implant stability quotient (ISQ) values and implant insertion variables. MATERIALS AND METHODS. Forty implants were inserted into two different types of pig rib bone. One group was prepared with conventional drills and a total of 20 implants were inserted into type I and type II bone. The other group was prepared with a Er,Cr:YSGG laser and a total of 20 implants were inserted into type I and type II bone. ISQ, maximum insertion torque, angular momentum, and insertion torque energy values were measured. RESULTS. The mean values for variables were significantly higher in type I bone than in type II bone (P < .01). In type I bone, the ISQ values in the drill group were significantly higher than in the laser group (P < .05). In type II bone, the ISQ values in the laser group were significantly higher than in the drill group (P < .01). In both type I and type II bone, the maximum insertion torque, total energy, and total angular momentum values between the drill and laser groups did not differ significantly (P ${\geq}$ .05). The ISQ values were correlated with maximum insertion torque (P < .01, r = .731), total energy (P < .01, r = .696), and angular momentum (P < .01, r = .696). CONCLUSION. Within the limitations of this study, the effects of bone bed preparation with Er,Cr:YSGG laser on the relationship between implant stability quotient (ISQ) values and implant insertion variables were comparable to those of drilling.

EFFECTS OF THE ER,CR:YSGG LASER ON BONE BED PREPARATION WITH VARIOUS LASER TIPS

  • Kim, Seong-Kyun;Heo, Seong-Joo;Koak, Jai-Young;Hong, Seong-Doo;Lee, Shin-Jae;Lee, Joo-Hee
    • The Journal of Korean Academy of Prosthodontics
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    • v.46 no.3
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    • pp.255-260
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    • 2008
  • STATEMENT OF PROBLEM: Preparation of implant beds with lasers is considered a safe and reliable method, but the accuracy of this technique has not been examined. PURPOSE: The purpose of this study was to evaluate the accuracy and effectiveness of implant bed preparation using an Er,Cr:YSGG laser. MATERIAL AND METHODS: An Er,Cr:YSGG laser was applied to pig rib bone. The laser was employed at a 5.75 W power setting, 30 Hz/sec pulse repetition, and 70 ${\mu}s$ pulse duration with 50 % water and 60% air spray. According to laser tips the groups were divided as follows; Group 1: paralleled - shaped sapphire tip (0.6 mm${\Phi}$), Group 2: paralleled - shaped zirconia tip (0.6 mm${\Phi}$), Group 3: tapered sapphire tip (0.4 mm${\Phi}$). The Er,Cr:YSGG laser tip was separated by 1 mm from the bone and applied for 15 seconds in a non-contact mode. After the application, the bone was sectioned for specimens. Histologic measurements were determined by computerized morphometry. The length of the prepared bone surface was measured and the width of the entrance was measured. The results were analyzed with one-way ANOVA (P<0.05). RESULTS: The prepared length of group 3 was longer than that of group 2. The prepared bone width was larger than the width of the laser tip in every group. Additional bone removal was observed adjacent to the prepared area and displayed an irregular surface. CONCLUSION & DISCUSSION: Different cutting effects were observed according to the laser tip, emphasizing the importance of proper tip selection in the clinical setting. This preliminary study supported the existence of hydrokinetic effects.