• IEIE Transactions on Smart Processing and Computing
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• v.5 no.2
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• pp.123-128
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• 2016

In this paper, an inversely tapered coupler with Bragg reflectors is reported for the first time. With appropriately positioned reflecting structures, our fiber-to-chip coupler can more efficiently transmit the light from fiber to a waveguide in a photonic integrated circuit (PIC). A numerical simulation evaluated the coupler's efficiency with the reflector. Optimized parameters that maximize the efficiency of the coupler are also investigated. Simulation results show that the reflector with appropriate parameters enhances efficiency by up to 7 dB. Likewise, Bragg metal reflectors implemented by the conventional metallization process can also improve efficiency. It is also shown that the proposed reflector enhances the coupling efficiency in a double-tip taper coupler.

• Bulletin of the Korean Mathematical Society
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• v.54 no.5
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• pp.1779-1801
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• 2017

Let X be a minimal del Pezzo surface of degree 2 over a finite field ${\mathbb{F}}_q$. The image ${\Gamma}$ of the Galois group Gal(${\bar{\mathbb{F}}}_q/{\mathbb{F}}_q$) in the group Aut($Pic({\bar{X}})$) is a cyclic subgroup of the Weyl group W($E_7$). There are 60 conjugacy classes of cyclic subgroups in W($E_7$) and 18 of them correspond to minimal del Pezzo surfaces. In this paper we study which possibilities of these subgroups for minimal del Pezzo surfaces of degree 2 can be achieved for given q.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.52 no.11
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• pp.657-661
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• 2003

In this paper, we designed a portable digital pressure algometer which not only can measure the pain level objectively and quantitatively, but also is able to do RF communication. This system consists of pressure sensor for pain measurement, analog signal analysis, digital hardware based on PIC16C73B, RF communication and display. To evaluate the performance of the developed system, we measured pressure threshold using commercial analog PA(Pressure Algometer) and the proposed system, and then evaluated the correlation and confidence. Using linear regression analysis, standard deviation of 0.1731 and R-square value of 99.3% were obtained. In conclusion, the above results showed good performance and its usability in measuring the pain clinically.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.553-556
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• 2008

A Magneto Plasma Sail(MPS) produces propulsive force by the interaction between the solar wind and an artificial magnetic field inflated by injecting plasma. Using a 2D hybrid PIC code, we evaluate the inflation of magnetic field when Argon(Ar) plasma with different ${\beta}_{in}$ including the value less than one is injected into the dipolar magnetic field generated by a superconducting coil. It is found that the magnetic field can be inflated by injecting plasma within an angle of $30^{\circ}$ in the polar direction and the magnetic field decays in the polar direction according to $B{\propto}r^{-2.4}$ after the plasma(${\beta}_{in}$=0.1) is injected.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.55 no.4
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• pp.231-237
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• 2006

This paper proposes an effective drive of high intensity discharge (HID) lamp ballast for cars. All control functions of the proposed ballast are implemented using a low-cost single chip microcontroller, PIC16C73 to optimize the total system size and to minimize cost through minimization of total component number. The proposed ballast generates high open-circuit voltage to ignite the lamp and is controlled to supply effectively the power required to shorten warm-up period after the breakdown. The DC-DC converter of the DC-AC converter part of the ballast utilizes the flyback converter topology that can minimize component number. Also, because to more minimize the ballast size, the transformer size must be minimized, for this, PWM (Pulse Width Modulation) pulses are generated with high frequency using the PWM module of the microcontroller. An analysis for this is explained, briefly. As if the operation of the lamp and ballast arrives at steady-state, then the ballast must AC-control the lamp, for this, the microcontroller utilizes the other PWM module. And the part related to the igniter is explained, briefly. It is shown through experimental results that the controller of the proposed ballast has good performance for the HID lamp for cars.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.51 no.10
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• pp.587-594
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• 2002

A low frequency square wave electronic ballast for the high intensity discharge(HID) lamps using fuzzy logic controller is developed. This electronic ballast consists a buck converter, a low frequency square wave full bridge inverter, a high voltage pulse generator for the HID lamp ignition, an over current protection circuit and an 8-bit microcontroller. The ballast system is operated on the constant current mode during the HID lamp start-up process and the system is operated on the constant power mode during steady state. Experimental results show that the fuzzy logic control operation is carried out successfully by the 8-bit microcontroller PIC16F877 In this electronic ballast system, in spite of the limited control bandwidth caused by low operating speed of the microcontroller, the good performance in the constant lamp current characteristic is obtained. Acoustic resonance of the HID lamps can be effectively avoided because the instantaneous In lamp power is fully constant due to the low frequency square wave drive.

• Journal of Microbiology and Biotechnology
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• v.24 no.2
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• pp.152-159
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• 2014

The regulation of protein tyrosine phosphorylation is mediated by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs) and is essential for cellular homeostasis. Co-expression of PTKs with PTPs in Pichia pastoris was used to facilitate the expression of active PTKs by neutralizing their apparent toxicity to cells. In this study, the gene encoding phosphatase PTP1B with or without a blue fluorescent protein or peroxisomal targeting signal 1 was cloned into the expression vector pAG32 to produce four vectors. These vectors were subsequently transformed into P. pastoris GS115. The tyrosine kinases EGFR-2 and $PDGFR{\beta}$ were expressed from vector pPIC3.5K and were fused with a His-tag and green fluorescent protein at the N-terminus. The two plasmids were transformed into P. pastoris with or without PTP1B, resulting in 10 strains. The EGFR-2 and $PDGFR{\beta}$ fusion proteins were purified by $Ni^{2+}$ affinity chromatography. In the recombinant P. pastoris, the PTKs co-expressed with PTP1B exhibited higher kinase catalytic activity than did those expressing the PTKs alone. The highest activities were achieved by targeting the PTKs and PTP1B into peroxisomes. Therefore, the EGFR-2 and $PDGFR{\beta}$ fusion proteins expressed in P. pastoris may be attractive drug screening targets for anticancer therapeutics.

• Journal of Microbiology and Biotechnology
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• v.24 no.4
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• pp.483-488
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• 2014

In order to improve the expression of heat-resistant xylanase XYNB from Aspergillus niger SCTCC 400264, XynB has been cloned into Pichia pastoris secretary vector pPIC9K. The XynB production of recombinant P. pastoris was four times that of E. coli, and the $V_{max}$ and specific activity of XynB reached $2,547.7{\mu}mol/mg$ and 4,757 U/mg, respectively. XynB still had 74% residual enzyme activity after 30 min of heat treatment at $80^{\circ}C$. From the van der Waals force analysis of XYNB (ACN89393 and AAS67299), there is one more oxygen radical in AAS67299 in their catalytic site, indicating that the local cavity is much more free, and it is more optimal for substrate binding, affinity reaction, and proton transfer, etc, and eventually increasing enzyme activity. The H-bonds analysis of XYNB indicated that there are two more H-bonds in the 33rd Ser of XYNB (AAS67299) than in the 33rd Ala(ACN89393 ), and two H-bonds between Ser70 and Asp67.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.444-448
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• 2005

This paper presents a developing procedure of the CAN-based real-time simulator for car body control, aiming at replacing the actual W/H (Wiring Harness) and J/B(Junction Box) couple eventually. The CAN protocol, as one kind of field-bus communication, defines the lowest 2 layers of the ISO/OSI standard, namely, the physical layer(PL) and the data link layer(DLL), for which the CSMA/NBA protocol is generally adopted. For CPU, two PIC18Fxx8x's are used because of their built-in integration of CAN controller, large internal FLASH memory (48K or 64K), and their costs. To control J/B's and actuators, 2 controller boards are separately implemented, between which CAN lines communicate through CAN transceivers MCP255. A power motor for washing windshield, 1 door lock motor, and 6 blink lamps are chosen for actuators of the simulator for the first stage. For the software architecture, a polling method is used for the fast global response time despite its slow individual response time. To improve the individual response time and to escape from some eventual trapped-function loops, High/Low ports of the CPU are simply used, which increases the stability of the actuator modules. The experimental test shows generally satisfactory results in normal transmitting / receiving function and message trace function. This simulator based on CAN shows a promising usefulness of lighter, more reliable and intelligent distributed body control approach than the conventional W/H and J/B couple. Another advantage of this approach lies in the distributed control itself, which gives better performance in hard real-time computing than centralized one, and in the ability of integrating different modules through CAN.

• Journal of Microbiology and Biotechnology
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• v.18 no.12
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• pp.1938-1944
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• 2008

The procpb gene encoding human procarboxypeptidase B (proCPB, GeneBank access code AJ224866) was cloned and its Pichia expression plasmid, $pPIC9{\alpha}$/hproCPB (9.2 kb), was constructed, in which procpb was under the control of the AOXl promoter and connected to the downstream of the mating factor ${\alpha}$-1 ($MF{\alpha}1$) signal sequence. The plasmid was linearized by digestion with Sacl, and integrated into the genome of P. pastoris strain GS115. By culturing of Pichia transformant on methanol medium, the human proCPB was successfully expressed and secreted into the culture supernatant. Moreover, Western blot analysis of the extracellular proteins showed proCPB bands clearly at a molecular mass of 45 kDa, confirming the expression of proCPB with its right size. The CPB activity reached about 3.5 U/ml and 12.7 U/ml in the flask and fermentor batch cultures of Pichia transformant, respectively. No CPB enzyme activity was found in the intracellular fraction. When the fed-batch cultivation was performed with methanol and glycerol mixture as a feeding medium, the extracellular CPB activity was increased to 42.0 U/ml, which corresponds to a 3.3-fold higher level of CPB activity than that of batch culture. The $K_m$ and $k_{cat}$ values of recombinant human CPB enzyme for hippuryl-$_L$-Arg as a substrate were estimated to be 0.16 mM and $11.93\;sec^{-1}$, respectively.