• Korean Journal of Psychosomatic Medicine
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• v.3 no.1
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• pp.91-97
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• 1995

Pain is a complex symptom consisting of a sensation underlying potenial disease and associated emotional state. Acute pain is a reflex biological response to injury, in contrast, chronic pain consists of pain of a mininum of 6 months duration and associates with physical, emotional past experience, economic resources of the patient, family and society. Moreover, chronic pain is characterized by physiological affective and behavioral responses that are quite different than those of acute pain. The different type of stimuli exciting pain receptor are mechanical, thermal and chemical stimli and chronic pain are concerned with three of all stimli. The major three components of pain central(Analgesia) system in the brain and spinal cord are 'periaqueductal gray area of the mesencephalon', 'the raphe magnus nucleus' and 'pain inhibitory complex located in the dorsal horns of the spinal cord'. But unfortunately, the central biochemical mechanisms of chronic pain are not clearly defined. To proper management of chronic pain, comprehensive urderstanding as a psychosomatic aspect and multidisciplinary therapeuti-team approach must be emphasized.

• Anxiety and mood
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• v.3 no.1
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• pp.8-14
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• 2007

Although treatments of anxiety symptom have been available for decades, the biological basis for anxiety disorders in humans is just beginning to emerge. Recently, there is a growing body of literature suggesting that group II metabotrpic glutamate (mGlu) receptors and group I mGlu receptors are important in the physiological and behavioral sequelae associated with stressful stimuli. Moreover, compounds selective for mGlu receptors, particularly mGlu2/3 and/or mGlu5, have proven as effective as classical anxiolytics in various animal models of anxiety without producing many of the unwanted side effects that are typical of current therapies. This article will focus on the emerging preclinical and clinical data that implicate modulation of the mGlu receptors as a potential anxiolytic strategy.

• Journal of Korean Medical classics
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• v.26 no.2
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• pp.1-7
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• 2013

Objective & Method : By investigating physiological function of tri-energizer, symptoms, and organ coordination, we obtained following conclusion. Tri-energizer is the membrane structure that surrounds the five visceral organs and six hollow organs, and filled with fluid. Tri-energizer acts as the passage for the flow of qi energy. Result & Conclusion : Therefore, dysfunction of the tri-energizer is caused by abnormal evaporation and metabolism. Upper-energizer regulates cardiopulmonary function, middle-energizer regulates spleen and stomach functions, and lower-energizer regulates liver, kidneys, small and large intestines, and bladder functions. Such a functional specialization is possible by receiving the source of qi through the wall wrapping around the internal organs. Tri-energizer represents the exterior and interior relationship by acting as the membrane structure supporting the five visceral organs and six hollow organs and at the same time, as the pericardium surrounding the heart.

• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.397-411
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• 1994

In the Oriental Medicine, the element of coldness is regarded as one of the important causes which induce female's diseases. Nowadays the number of the female patients is ascending that serously appeal the coldness-sense and pain-sense at the particular part of the body, for example, hand, foot, abdomen, waist, external genital portion and so on. These are caused by female's physiological characteristics of the menstration and delivery, and the influence of the life circumstances, for example, the clothes briefness, the overdiet, oversetting of the airconditioner. The Female's Part-Coldness Syndrome is a disease which the oriental people better than the western people suffer from and if it would be sick for a long time, it could brings into the other diseases. The Oriental Medicine have better effects by the diagnosis and treatment according per symptom in the contrast with the Western Medicine having difficulties in the point of accurate diagnosis and treatment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.4
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• pp.835-839
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• 2005

I studied on the correlativity with an individual constitution and etiological factor, the results are as follows. As the external wickedness invade into human body, the condition of an individual constitution determine whether being attacked with a disease or not. Moreover the contracting and the tendency of a disease are determined from the peculiarity of an individual constitution. And whether being attacked with a disease or not, the contracting and the tendency are possible explained of DONG-GI-SANG-GU(the indentical vigour looking for mutually). The division on the malice for cause of a disease and the symptom of a disease are more and more necessary.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.6
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• pp.1715-1719
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• 2005

Delirium is a set of symptoms that includes Disturbance of consciousness, attention, cognition, sleep-wake cycle. It usually appears as a disease progresses. Also it can be considered as one of byun-jo(煩躁)'s symptoms because it shows similar symptom and progress to byun-jo(煩躁). One patient was admitted who was suffering delirium, restlessness, chest discomfort, disorientation. The patient was diagnosed as delirium and byun-jo that was caused by heat in the heart and stomach, and was treated with Chungul-san(淸鬱散). In the course of treatment, symptoms improved gradually. Resu suggest that Chungul-san(淸鬱散) is effective on delirium, byun-jo caused by heat in stomach.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.2
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• pp.197-205
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• 2010

The association between five limpness(五軟), five stiffness(五硬), five retardation and disease have been repeatedly shown in patient. However, comparative study has been rare. This study arrange disease, which answer to five limpness, five stiffness, five retardation and classify by epiologic diagnosis. We search for scientific journals, medical college texts, theses of a degree and collect case reports. In this study we found that the five retardation(N=56) is showing numerous more than the others. The five stiffness(N=14) is showing rare than the five limpness(N=29). The five limpness is overlapping more than 90% with five retardation. and the five stiffness is overlapping 80% with five retardation. Symptom of five limpness, five stiffness, five retardation is coming out independent and overlapping each others. And generally it accompanies with abnormality in central nervous system.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.1105-1110
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• 2010

The purpose of this case study is to report the effect of oriental medical treatment on chronic tension-type headache. Despite the patient was treated by cervical nerve block for headache, headache was not improved. We diagnosed chronic tension-type headache according to ICHD-II(The International Classification of Headache Disorders) and Qi deficiency, dampness and phlegm by oriental differential diagnosis of symptom and signs. We applied herbal medicine, acupuncture, moxibustion and cupping therapy for hospitalization(7 days). Oriental medical treatment may have effective results in treating chronic tension-type headache that was not improved by cervical nerve block treatment. But this is a single case study, so further case-series research should be compiled.

• Molecules and Cells
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• v.39 no.9
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• pp.645-653
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• 2016

Morphine is the most potent analgesic for chronic pain, but its clinical use has been limited by the opiate's innate tendency to produce tolerance, severe withdrawal symptoms and rewarding properties with a high risk of relapse. To understand the addictive properties of morphine, past studies have focused on relevant molecular and cellular changes in the brain, highlighting the functional roles of reward-related brain regions. Given the accumulated findings, a recent, emerging trend in morphine research is that of examining the dynamics of neuronal interactions in brain reward circuits under the influence of morphine action. In this review, we highlight recent findings on the roles of several reward circuits involved in morphine addiction based on pharmacological, molecular and physiological evidences.

• Journal of the Korean Home Economics Association
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• v.41 no.6
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• pp.167-183
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• 2003

This study reviewed the literature pertaining to the cause and effects of job stress. Many definitions of stress have been offered and the diversity of these definitions has been generated by medical scientists, psychologists, and behavioral scientists. Most approaches dealing with job stress have involved listing of various sources of job stress, moderators, and outcomes. This study is concerned with the selection of variables, the relationships between job stressors and outcomes, and the effects of moderators on these relationships investigated in job stress research. A review of job stress literature presents that various job stressors (e. g., task characteristics, role characteristics, organizational characteristics, career development, and relationships), moderators (e. g., locus of control, type A and B personality, social support, and demographics), and outcomes (e. g., perceived stress, job satisfaction, job commitment, organizational commitment, performance, turnover, and physiological symptoms) were used for a greater understanding of job stress.