• 혜화의학회지
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• 제10권1호
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• pp.489-494
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• 2001

To determine the preventive effect of Samulanshintang (SA) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a day for 3 days. During application of stress, body weight of rats was measured. After sacrifice, 4 organs were taken for measurement of organ weight. Brain was homogenated and its catecholamine and serotonin contents were measured with HPLC. In our study, stress mainly induced increase of concentration of neurotransmitters in brain without other significant physical change of rats. SA inhibited stress induced changes of neurotransmitter content in brain.

• Journal of Plant Biology
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• 제1권2호
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• pp.1-4
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• 1958

1. A vernalized Korean rye was exposed to Co60 in dose of 150r (dose rate was 7r per minute) and pollen mother cells were examined for cytological study. 2. According to the observation, it is quite clear that scraping of chromosomes soon after irradiation and surface stickiness at the period of 6 hours after irradiation were followed by structural changes at the period of 12 hours after irradiation.

• 한국섬유공학회:학술대회논문집
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• 한국섬유공학회 1997년도 추계총회 및 학술발표회 논문집
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• pp.364-368
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• 1997

The purpose of this Study was to determine thermal sensation and physiological responses for men in summer indoor environment, under various air temperature and relative humidity, with male university students. Subjective Evaluation, Heart Rate Variability(HRV), Electroencephalogram(EEG) were examined. We found that comfort of people was achieved at 50% R.H., 24C, and the difference of skin temperature was found at the calf area as air temperature changes. At low air temperature and low humidity, heart rate was decreased, but there was no change at brain wave, keeping a-wave.

• Journal of Pharmaceutical Investigation
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• 제13권2호
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• pp.51-58
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• 1983

In order to elucidate the effects of Panax Ginseng on the pharmacokinetic parameters of nalidixic acid in a patho-physiological changes, the kinetics of the disappearance of the drug from the blood, appearance in the bile and urinary excretion were studied in $CCl_4-toxicated$ rabbits. The pharmacokinetics of the drug nalidixic acid in rabbits were modeled by a two compartment. Total saponin, water extract from Panax Ginseng, significantly decreased biliary and urinary excretion of nalidixic acid.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2019년도 추계학술대회
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• pp.20-20
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• 2019

• 한국작물학회:학술대회논문집
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• 한국작물학회 2021년도 춘계학술대회
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• pp.82-82
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• 2021

• 대한치과교정학회지
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• 제50권5호
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• pp.324-335
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• 2020

Objective: To compare postoperative positional changes in the mandibular proximal segment between the conventional orthognathic surgery (CS) and the surgery-first approach (SF) using intraoral vertical ramus osteotomy (IVRO) in patients with Class III malocclusion. Methods: Thirty-eight patients with skeletal Class III malocclusion who underwent bimaxillary surgery were divided into two groups according to the use of preoperative orthodontic treatment: CS group (n = 18) and SF group (n = 20). Skeletal changes in both groups were measured using computed tomography before (T0), 2 days after (T1), and 1 year after (T2) the surgery. Three-dimensional (3D) angular changes in the mandibular proximal segment, condylar position, and maxillomandibular landmarks were assessed. Results: The mean amounts of mandibular setback and maxillary posterior impaction were similar in both groups. At T2, the posterior portion of the mandible moved upward in both groups. In the SF group, the anterior portion of the mandible moved upward by a mean distance of 0.9 ± 1.0 mm, which was statistically significant (p < 0.001). There were significant between-group differences in occlusal changes (p < 0.001) as well as in overjet and overbite. However, there were no significant between-group differences in proximal segment variables. Conclusions: Despite postoperative occlusal changes, positional changes in the mandibular proximal segment and the position of the condyles were similar between CS and SF, which suggested that SF using IVRO achieved satisfactory postoperative stability. If active physiotherapy is conducted, the proximal segment can be adapted in the physiological position regardless of the occlusal changes.

• 디지털융복합연구
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• 제12권1호
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• pp.467-473
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• 2014

본 연구의 목적은 점진적 이완기법을 대학 양궁선수들에게 적용한 후 뇌파측정과 혈압, 심박수 등의 생리적인 변인의 측정을 통하여, 호흡을 통한 점진적 이완의 효과성을 검증하고 궁극적으로 양궁의 경기수행력을 향상시키는데 목적이 있다. 본 연구의 대상자들은 여자 양궁선수 13명을 대상자로 선정하였고, 12주간 Jacobson의 점진적 이완기법을 적용하여 1주일에 3일, 1회 약 15~20분 동안 훈련 후, 동일 대상자 13명의 뇌파와 혈압, 심박수를 측정하였다. 본 연구의 자료처리는 SPSS18.0프로그램을 이용하여 실험 대상자의 일반적인 특정을 알아보기 위하여 기술분석을 실시하였고 단일 집단의 뇌파, 혈압, 심박수의 사전 사후의 변화를 알아보기 위하여 대응 t-test(paired t-test)를 실시하였다. 모든 통계적 유의 수준은 ${\alpha}=0.5$로 하였고, 다음과 같은 결과를 얻었다. 첫째, 12주간 처치 후 상대 ${\alpha}$파, 상대 ${\beta}$ 중에서 상대${\alpha}$파가 통계적으로 유의한 수준으로 증가하였고, 상대 ${\beta}$파의 변화는 나타내지 않았다. 둘째, 12주간 처치 후 혈압의 변화로는 수축기압의 변화는 나타내지 않았고, 이완기 혈압의 변화가 통계적으로 유의한 수준으로 나타났다. 셋째, 심박수의 변화는 통계적으로 유의하게 나타나지 않았다. 이상의 결과를 종합하여 볼 때 호흡을 통한 점진적 이완기법은 대학 양궁선수들에게 긍정적인 영향을 미치는 것으로 나타났다.

• The Korean Journal of Physiology
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• 제30권2호
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• pp.289-297
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• 1996

Excitatory amino acids (EAA) are thought to play an important role in producing cell death associated with ischemic and traumatic spinal cord injury. The present study was carried out to determine if the response characteristics of spinal sensory neurons in segments adjacent to degeneration sites induced by EAA are altered following these morphological changes. Intraspinal injections of quisqualic acid (QA) produced neuronal degeneration and spinal cavitation of gray matter. The severity of lesions was significantly attenuated by pretreatment with a non-NMDA antagonist NBQX. In extracellular single unit recordings, dorsal horn neurons in QA injected animal showed the increased mechanosensitivity, which included a shift to the left in the stimulus-response relationship, an increased background activity and an increase in the duration of after-discharge responses. Neuronal responses, especially the C-fiber response, to suprathreshold electrical stimulation of sciatic nerve also increased in most cases. These results suggest that altered functional states of neurons may be responsible for sensory abnormalities, e.g. allodynia and hyperalgesia, associated with syringomyolia and spinal cord injury.

• BMB Reports
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• 제50권11호
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• pp.537-538
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• 2017

Hypoxia affects various physiological and pathophyological processes. Hypoxia changes the expression of hypoxia-responsive genes through two main pathways. First, hypoxia activates transcription factors (TF) such as Hypoxia-inducible Factor (HIF). Second, hypoxia decreases the activity of Jumonji C domain-containing histone demethylases (JMJDs) that require $O_2$ and ${\alpha}$-Ketoglutarate (${\alpha}$-KG) as substrates. The JMJDs affect gene expression through their regulation of active or repressive histone methylations. Profiling of H3K4me3, H3K9me3, and H3K27me3 under both normoxia and hypoxia identified 75 TFs whose binding motifs were significantly enriched in the methylated regions of the genes. TFs showing similar binding strengths to their target genes might be under the 'metabolic control' which changes histone methylation and gene expression by instant changing catalytic activities of resident histone demethylases.