• Journal of Pharmaceutical Investigation
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• v.16 no.1
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• pp.36-41
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• 1986

The ground mixtures of ketoprofen with chitin or chitosan were prepared by grinding in a ball mill to increase the dissolution rate. The ground mixture showed a faster and more enhanced dissolution rate than the physical mixture or intact ketoprofen. The X-ray diffraction peaks indicated the production of the amorphous form of ketoprofen in the ground mixture. An interaction, in the ground mixture, such as association between the functional groups of ketoprofen and chitin or chitosan might occur in the molecular level. The endothermic peak due to the fusion of ketoprofen disappeared in the ground mixture indicating the different thermal property. The co-grinding technique with chitin or chitosan provided a promising way enhancing the dissolution rate of practically insoluble drug.

• Journal of Pharmaceutical Investigation
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• v.20 no.4
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• pp.193-198
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• 1990

To increase the dissolution rate of furosemide, cogrinding or coprecipitating of furosemide with povidone was carried out. The ground mixture of furosemide with povidone was prepared by cogrinding in a ceramic ball mill and the coprecipitate was prepared by solvent method using methanol. The povidone ground mixture and the coprecipitate showed a faster and more enhanced dissolution rate than the physical mixture or intact furosemide. The IR, DTA and TGA studies showed the physicochemical modifications of furosemide from the ground mixture and the coprecipitate. An interaction, in the ground mixture and in the coprecipitate, such as association between the functional groups of furosemide and povidone might occur in the molecular level. The coprecipitating and cogrinding techniques with povidone provided a promising way to increase the dissolution rate of poorly soluble drugs.

• Journal of the Korean Society of Clothing and Textiles
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• v.22 no.4
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• pp.525-534
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• 1998

Cotton fabrics were finished with mixture of BTCA(1,2,3,4,-butanetetracarboxylic acid) and polyalkyleneoxide-modified amino-functional silicone by pad-dry-cure process to achieve better DP performance with a higher retention of physical properties as compared to those of finished with BTCA alone. The results indicated that BTCA improved the wrinkle recovery but reduced significantly the tensile and tear strength of the treated fabrics. Whereas silicone imparted a lower wrinkle recovery, a lower loss of tensile strength than BTCA, in addition improved considerably the tear strength owing to reduction in inter-fiber and/or inter-yarn frictional forces. The concentration and curing temperature needed to enhance physical properties were as follows; for BTCA treatments 6%, at 18$0^{\circ}C$, for silicone treatments 1% at 14$0^{\circ}C$. This optimum concentration of silicone was observed by using the mixture of BTCA and silicone. The wrinkle recovery and DP rating of cotton fabrics treated with mixture of 4% BTCA and 1% silicone at a curing temperature of 17$0^{\circ}C$ was similar to those of treated with 6% BTCA at a curing temperature of 18$0^{\circ}C$, and other performance properties observed were; an increase in tensile strength, extension, toughness, abrasion resistance and moisture regain due to the reduction of BTCA concentration and curing temperature, futhermore an improvement in bending and surface properties due to the lubricating effect of silicone. On the other hand 1% aqueous silicone solution showed the lowest surface tension. Such nonionic surface activity resulted in a more uniform and rapid deposition of BTCA on the fiber or fabric.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1000-1007
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• 2011

This study was conducted to determine the analgesic effect of onion and acanthopanax senticosus mixture extract using the rheumatoid arthritis rat model. Rheumatoid arthritis model was made by the intradermal injection of type II collagen emulsified. Rats were divided into four groups: (1) Sham group(n=5), (2) Control group(administered DW 3 $m{\ell}$/1 day after RA induced, n=7), (3) Experimental group I(administered Onion extractor 600 mg/3 $m{\ell}$/1 day after RA induced, n=7). (4) Experimental group III(administered Onion and Acanthopanax senticosus mixture extractor 600 mg/3 $m{\ell}$/1 day after RA induced, n=7). After that, we examined the arthritic index, paw edema, pain threshold at 1st, 14th, 28th days. And also we examined histopathologic study(safranin-O green), immunohistochamical stain(COX-2) of knee joint at 28th days. Arthritic index, paw edema and pain threshold test were decrease in experimental group I, II than control group. Especially group II was most significantly inhibit effect than the other groups at 28th days. On the histopathologic view, all experimental groups were relieved and reproduced the erosion of arthritic site compared with control group. All experimental groups were COX-2 positive cells in the immunohistological stain of the knee joint were significantly decreased compared with control group. Especially group II was most significantly decreased than the other groups at 28th days. Onion and Acanthopanax senticosus mixture extractor can be used for curing rheumatoid arthritis. Anti-inflammatory effects may be somewhat better in combination of Onion and Acanthopanax senticosus.

• Asian Journal of Turfgrass Science
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• v.23 no.2
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• pp.271-278
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• 2009

This study was conducted to investigate the effect of the mixture ratio of the inorganic soil amendments on the soil physicochemical properties. In this experiment, three kinds of soil amendments which had similar pH, EC and particle size, the A, B and C, were tested. The mixture ratio of soil amendment were 0%, 3%, 5%, 7% and 10% (V/V) incorporated with sand which met to the USGA(United State of Golf Association) particle standard. To analyze the effects of amendment on chemical soil properties, pH, EC(electrical conductivity) and CEC(cation exchangeable capacity) were measured. The porosity, bulk density and hydraulic conductivity also measured to analyze the changes of physical properties. In the chemical properties, pH was significantly related to the mixture ratios of amendments, A and C(P<0.05), CEC and EC also related to the ratios of C(P<0.01). When the results were applied to the USGA standard of the soil physical properties, the optimum mixture ratios of each amendment were 3% in A and B, and 7~10% in C. To analyze the corelation of mixture ratio versus to physical character, volume of porosity was significantly related to the ratio of B (P<0.05), and showed similar corelation in porosity and hydraulic conductivity with ratio of C(P<0.05). These results indicate that types and mixture ratio of inorganic soil amendments should affect on soil physio-chemical properties of root zone on USGA sand green.

• Journal of the Korean Geotechnical Society
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• v.29 no.2
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• pp.57-64
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• 2013

In this paper, in order to solve high water content of water sludge and promote its recycle, sludge mixtures with various mixing ratios were produced. Sludge mixture consisted of water sludge and weathered granite soil. Their physical properties and unsaturated characteristics (soil-water characteristic curve, and unsaturated permeability function) were investigated by laboratory tests. Experimental test results indicated that at a given matric suction volumetric water content of sludge mixture increased as water sludge content increased. Air entry values of sludge mixture increased from 0.9 kPa to 2.4 kPa with an increase in water sludge content or fine content. In addition, unsaturated permeability function, which is an important factor for performing infiltration analysis, was predicted using saturated permeability and soil-water characteristic curve of sludge mixture.

• Journal of the Korean institute of surface engineering
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• v.29 no.6
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• pp.834-838
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• 1996

The diagnosis of the plasma in the facing targets sputtering system was performed in mixture gas of Ar 0.18-0.0 Pa, Xe 0.0-0.18 Pa and $O_2$ 0.02 Pa by using Langmiur's probe and the effect of plasma-damage to surface smoothness and magnetic characteristics of Ba ferrite films was clarified. The electron density $N_e$ and the electron temperature $T_e$ were evaluated at the center of the plasma and at the neighborhood of the anode ring. $T_e$ decreased and $N_e$ increased with increase of $P_{Xe}$ at the center of plasma. For the measurement at the neighborhood of the anode ring, $T_e$ was almost constant and $N_e$ took the minimum value at $P_{Xe}$ of 0.1 Pa, where Ba ferrite films with excellent c-axis orientation and magnetic characteristics were obtained. It was suggested that the restriction of the bombardment of recoiled particles as well as the suppress of plasma-damage were effective for obtaining good surface smoothness and excellent magnetic characteristics and it was useful for decreasing the crystallization temperature of Ba ferrite films.

• Journal of the Korea Organic Resources Recycling Association
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• v.2 no.2
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• pp.77-88
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• 1994

This experiment was carried out to investigate the effect of sewage sludge compost amended soils on the growth and accumulation patterns of heavy metals in plant parts of Orchardgrass seedlings, changes in physical properties and chemical composition, and heavy metal residue in soils. Mixture ratios of sewage sludge compost and soil(loam) were 100:0, 80:20, 60:40, 40:60, 20:80 and 0:100(control), respectively. The results obtained were as follows; 1. The physical properties and chemical compostion of soils were improved by increase in mixture ratios of sewage sludge compost. 2. The biological yield of Orchardgrass seedlings was increased with mixture ratios of sewage sludge compost. 3. The dry weight of shoot(SH) was increased with both of yield components(NT and WT) and biological yield of Orchardgrass seedlings. 4. The total nitrogen concentrations(TN) of plants was increased with quadratically up to the biological yield of 100% mixture ratio of sewage sludge compost. 5. Lead(Pb) concentration of soil in over the 60% mixture ratios of sewage sludge compost were in excess of limiting level(50ppm) of organic fertilizers.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.03a
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• pp.489-494
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• 2010

A geo-composite soil (GCS) is a stabilized mixture of bottom ash, cement and dredged soil. Various samples with different mass ratios of mixtures were tested under curing time of 7 and 28 days to investigate physical properties and compressive strength. This paper focused on the effect of bottom ash on the strength characteristics of Busan marine dredged soil. Cement has been added as an additive constituent to enhance self-hardening of the blended mixture. The unconfined compressive strength of GCS increases with an increase in curing time due to pozzolanic reaction of the bottom ash. The strength after 28 days of curing is found to be approximately 1.3 to 2.0 times the strength after 7 days of curing, regardless of mixture conditions. The secant modulus of GCS is in the range of 55 to 134 times the unconfined compressive strength. The correlation of unconfined compressive strength with bottom ash content and initial void ratio are suggested.

• International Journal of Highway Engineering
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• v.18 no.6
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• pp.97-104
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• 2016

OBJECTIVES : The objective of this research is to develop additives for the modification of Solvent DeAsphalting Residue (SDAR) to be used as pavement materials, and evaluate the performance of asphalt mixture manufactured using the SDAR modified by developed additives. METHODS : The SDAR generally consists of more asphaltenes and less oil components compared to the conventional asphalt binder, and hence, the chemical/physical properties of SDAR are different from that of conventional asphalt binder. In this research, the additives are developed using the low molecular oil-based plasticizer to improve the properties of SDAR. First, the chemical property of two SDARs is analyzed using SARA (saturate, aromatic, resin, and asphaltene) method. The physical/rheological properties of SDARs and SDARs containing additives are also evaluated based on PG-grade method and dynamic shear-modulus master curve. Second, various laboratory tests are conducted for the asphalt mixture manufactured using the SDAR modified with additives. The laboratory tests conducted in this study include the mix design, compactibility analysis, indirect tensile test for moisture susceptibility, dynamic modulus test for rheological property, wheel-tracking test for rutting performance, and direct tension fatigue test for cracking performance. RESULTS : The PG-grade of SDARs is higher than PG 76 in high temperature grades and immeasurable in low temperature grades. The dynamic shear modulus of SDARs is much higher than that of conventional asphalt, but the modified SDARs with additives show similar modulus compared to that of conventional asphalt. The moisture susceptibility of asphalt mixture with modified SDARs is good if, the anti-stripping agent is included. The performance (dynamic modulus, rutting resistance, and fatigue resistance) of asphalt mixture with modified SDARs is comparable to that of conventional asphalt mixture when appropriate amount of additives is added. CONCLUSIONS : The saturate component of SDARs is much less than that of conventional asphalt, and hence, it is too hard and brittle to be used as pavement materials. However, the modified SDARs with developed additives show comparable or better rheological/physical properties compared to that of conventional asphalt depending on the type of SDAR and the amount of additives used.