• Title/Summary/Keyword: physical evidence

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Molecular gas properties under ICM pressure: A Case study of NGC4402

  • Hahn, You-Jin;Chung, Ae-Ree
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.1
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    • pp.41.1-41.1
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    • 2012
  • Interactions between the galactic interstellar medium (ISM) and the intra cluster medium (ICM) are believed to be one of the main processes affecting galaxy evolution in cluster environments. The aim of our research is to study the molecular gas properties of a galaxy under the ICM pressure in the cluster environment. It has been well known that cluster galaxies are deficient in atomic hydrogen gas (HI gas) compared to their field counterparts and now there is much evidence that low density ISM is being removed by ram pressure due to ICM wind. Meanwhile, no significant molecular gas deficiency of the cluster galaxy population has been found yet they show overall lower star formation rate than galaxies in the field, and it is still puzzling how the star formation could decrease without stripping of dense molecular gas. To address this issue, we probe the detailed molecular gas properties of NGC 4402, located near the cluster center, as part of a study of four spiral galaxies in the Virgo Cluster. NGC 4402 is well known undergoing ram pressure stripping with a truncated HI disk($D_{HI}/D_{opt}$ - 0.75 and only 36% of HI gas compare to field galaxies of a similar size) and a disturbed gas morphology. Comparing the high resolution 12CO and 13CO data of NGC 4402 from the Sub Millimeter Array (SMA) with existing other wavelength data, we probe the spatial distribution and a physical condition of molecular gas under strong ICM pressure. We discuss the star formation activity might have been altered and hence how the global color of NGC4402 would change in the future.

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Satellites of Isolated Early-type Galaxies and the Missing Satellite Galaxy Problem

  • Park, Changbom;Hwang, Ho Seong;Park, Hyunbae;Lee, Jong Chul
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.39.1-39.1
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    • 2017
  • The standard hierarchical galaxy formation scenario in the popular LCDM cosmogony has been very successful in explaining the large-scale distribution of galaxies. However, one of the failures of the theory is that it predicts too many satellite galaxies associated with massive galaxies compared to observations, which is called the missing satellite galaxy problem. Isolated groups of galaxies hosted by passively evolving massive early-type galaxies are ideal laboratories for finding the missing physics in the current theory. We discover through a deep spectroscopic survey of galactic satellite systems that bright isolated early-type galaxies have almost no satellite galaxies fainter than the r-band absolute magnitude of about Mr=-14. The cutoff is at somewhat brighter magnitude of about Mr=-15 when only early-type satellites are used. Such a cutoff is not observed in the luminosity function of galaxies in the field. Physical properties of the observed satellites depend sensitively on the host-centric distance. All these are strong evidence that galactic satellites can become invisible due to astrophysics of satellite-host galaxy interaction. A recent state-of-the-art hydrodynamic simulation of galaxy formation does not reproduce such a cutoff in the satellite galaxy luminosity function. But the past history of the simulated satellites shows that many satellite galaxies near or somewhat fainter than the cutoff magnitude have recently become extinct through fatal encounters with the host or other satellite galaxies. Our observation indicates that the missing satellite galaxy problem could be mitigated if the astrophysics of galaxy interaction is more elaborated in the theory.

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Firefighters and Posttraumatic Stress Disorder (소방공무원과 외상 후 스트레스 장애)

  • Ryu, Jia;Ha, Eunhee;Jeong-Choi, Kyunghee;Kim, Jieun E.;Park, Shinwon;Kim, Hyunjoo
    • Korean Journal of Biological Psychiatry
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    • v.24 no.1
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    • pp.10-18
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    • 2017
  • Occupational hazards of firefighting and rescue works include frequent exposure to emergencies and life-threatening situations. These stressful work conditions of being constantly under pressure and exposed to potentially traumatic events put them at higher risk of developing posttraumatic stress disorder (PTSD), compared to the general population. PTSD is a potentially debilitating mental disorder, due to persistent intrusive thoughts, negative alterations of mood and cognition, hypervigilance, avoidance of similar situations and reminders, and re-experiences of the traumatic event. Previous studies have shown a relatively high prevalence of PTSD among firefighters, indicating the need for a systematic approach of early detection and prevention. Therefore, a critical review of the current literature on PTSD in firefighters would provide valuable insights into developing effective prevention and intervention programs. Literature indicated that there are risk factors of PTSD in firefighters, such as pre-existing depression, anxiety, sleep disorders, occupational stress, physical symptoms, and binge drinking, whereas social support and adequate rewards are protective factors. Although there are differences in the prevalence of PTSD across studies, partly due to various assessment tools utilized, different sample sizes, and sample characteristics, over one tenth of the firefighters were estimated to have PTSD. The current review warrants further investigations to precisely assess PTSD and co-morbid mental disorders, functional outcomes, and associated factors, and to develop evidence-based preventive and interventional programs to help firefighters with PTSD.

Inhibitory effect of mushrooms extract on TNF-α/INF-γ induced-cytokine in human keratinocytes, HaCaT (버섯류 추출물의 피부각질세포(HaCaTcell) 내 염증성 사이토카인 억제효과)

  • Choi, Eun-Ju;Kim, Eun-Kyung;Ji, Yong-Seok;Lee, Chang-Jin
    • Journal of Mushroom
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    • v.13 no.3
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    • pp.170-174
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    • 2015
  • Mushroom is known for anti-inflammatory and anti-oxidative potential. This study provides evidence that the inhibitory effect of mushroom on the expression of pro-inflammatory cytokines in human keratinocytes, HaCaT cells. To define the underlying mechanisms of action, tumor necrosis factor${\alpha}$/$IFN{\gamma}$-activated human keratinocytes model was used. Mushroom significantly inhibited the expression of cytokines in HaCaT cells. Taken together, the results demonstrate that mushroom inhibited inflammtion, suggesting that mushroom (DW extract: Grifola frondosa Cordyceps militaris), (Ethanol extract: Ganoderma lucidum, Lentinus edodes, Cordyceps militaris, Flammulina velutipes) might be a candidate for the treatment of skin inflammation.

One Case of Stroke in Childhood (소아중풍(小兒中風) 환자(患者)에 대한 치험(治驗) 1례(例))

  • Park, Eun-Jung;Lee, Hai-Ja;Na, Won-Kyeung;Jang, Sung-Jin;Ahn, Jai-Sun;Han, Kyeung-Hoon
    • The Journal of Pediatrics of Korean Medicine
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    • v.18 no.2
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    • pp.21-30
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    • 2004
  • Objectives : The purpose of this study is case report of stroke in childhood. The childhood cerebrovascular diseases are interesting than those seen in adulthood, because the etiology and prognosis of the disease in children are quite different from those of adults. Cerebrovascular diseases in children is more common than once recognized. However, relatively little attention has been paid to the epidemiology of childhood stroke. Methods : We experienced one case of ischemic stroke in childhood whose symptoms are similar to that of adults. There is no evidence of cerebrovascular malformation at MRI, MRA film. The cause of stroke is undetermined and just we can see the little infarction lesion on Lt. pons. We treated the patient with herb medicine, acupuncture-Tx, negative-Tx, moxa-Tx and physical treatment. Results : After the treatment of oriental medicine, the patient recovered from the stroke symptoms. Conclusion : we thought that the more follow-up is needed. So we repoert one case of cerebral infarction in children that recovered from stroke symptoms after the treatment of oriental medicine.

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Medical Treatment of Laryngopharyngeal Reflux (인후두역류의 약물치료)

  • Chu, Hyung-Ro
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.18 no.2
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    • pp.108-112
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    • 2007
  • Otolaryngological manifestations of acid reflux include a wide range of pharyngeal and laryngeal symptoms ; and the constellation of symptoms has been called laryngopharyngeal reflux (LPR). In the absence of definite diagnostic criteria, LPR disease remains a subjective entity. A diagnosis of LPR is usually based on response of symptoms to empirical treatment. Investigative modalities such as pH monitoring and, more recently, impedance studies are generally reserved for treatment failures. LPR usually requires more aggressive and prolonged treatment to achieve regression of both symptoms and laryngeal findings. The suppression of gastric acid and secretion with anti-secretary agents has been the mainstay of medical treatment for patients with acid-related disorders. The suppression of gastric acid secretion achieved with Hz-receptor antagonist $(H_2RA)$ has proved suboptimal for relief of reflux symptoms. The rapid development of tolerance and rebound acid hypersecretion after the with-drawal of $H_2RA$ limit their clinical use. Proton pump inhibitors (PPI) have been proved to be very effective for suppressing intragastric acidity, but the optimal dose and duration is unknown. Current evidence indicates that pharmacologic intervention should include, at a minimum, a 3 month trial of twice daily PPI. Symptoms of LPR improve over 2 months of therapy. The physical findings of LPR resolve more slowly than the symptoms and this continues through out at least 6 months of treatment. For most patients with LPR, twice daily dosing with a PPI is usually recommended for an initial treatment for a period of no less than 6 months treatment, and lifetime treatment may be required.

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Use of Complementary and Alternative Medicine in Patients with Gynecologic Cancer: a Systematic Review

  • Akpunar, Dercan;Bebis, Hatice;Yavan, Tulay
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7847-7852
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    • 2015
  • Purpose: Research carried out with gynecologic cancer patients using CAM was reviewed to provide a source for discussing which CAM method is used for which purpose, patients' perceptions on the effects/side effects occurred during/after using CAM and their sources of information regarding CAM. Materials and Methods: This literature review was carried out for the period between January 2000 and March 2015 using Scopus, Dynamed, Med-Line, Science Dırect, Ulakbim, Research Starters, Ebscohost, Cinahl Complete, Academic Onefile, Directory of Open Access Journals, BMJ Online Journals (2007-2009), Ovid, Oxford Journal, Proquest Hospital Collection, Springer-Kluwer Link, Taylor & Francis, Up To Date, Web Of Science (Citation Index), Wiley Cochrane-Evidence Base, Wiley Online Library, and Pub-Med search databases with "complementary and alternative medicine, gynecologic cancer" as keywords. After searching through these results, a total of 12 full length papers in English were included. Results: CAM use in gynecologic cancer patients was discussed in 8 studies and CAM use in breast and gynecologic cancer patients in 4. It was determined that the frequency of CAM use varies between 40.3% and 94.7%. As the CAM method, herbal medicines, vitamins/minerals were used most frequently in 8 of the studies. When the reasons why gynecologic cancer patients use CAM are examined, it is determined that they generally use to strengthen the immune system, reduce the side effects of cancer treatment and for physical and psychological relaxation. In this review, most of the gynecologic cancer patients perceived use of CAM as beneficial. Conclusions: In order that the patients obtain adequate reliable information about CAM and avoid practices which may harm the efficiency of medical treatment, it is recommended that "Healthcare Professionals" develop a common language.

Quality of Life of Multiethnic Adolescents Living with a Parent with Cancer

  • Ainuddin, Husna A.;Loh, Siew Yim;Low, Wah Yun;Sapihis, Musaropah;Roslani, April Camilla
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6289-6294
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    • 2012
  • Background: Research evidence suggests a debilitating impact of the diagnosis of cancer on the quality of life of the afflicted individuals, their spouses and their families. However, relatively few studies have been carried out on the impact on the QOL of adolescents living with parents diagnosed with cancer. This paper presents a sub-analysis on the impact of parental cancer (colorectal, breast and lung) on adolescents. Materials and Methods: This is a cross-sectional study on adolescents aged 13-18 years old. Upon ethical clearance obtained from UMMC Medical Ethics Committee, patients with colorectal, breast or lung cancer and their adolescent children were recruited from the Clinical Oncology Unit of University of Malaya Medical Centre. Respondents who gave consent completed a demographic questionnaire and the Pediatric Quality of Life Inventory, via the post, email, home visit or meetings at the clinics. Results: 95 adolescents from 50 families responded, giving a response rate of 88 percent. The adolescent's mean age was 16 years (ranging between 13-18 years). Adolescents with parental cancer had the lowest mean score in emotional functioning (p<0.05). Male adolescents had significantly higher quality of life overall and in physical functioning compared to female adolescents. Adolescents with a father with cancer had better school functioning compared to adolescents whose mothers had cancer. Families with household income of RM 5000 and above have significantly better quality of life compared to families with lower household income. Conclusions: Adolescent sons and daughters of parents with a cancer diagnosis show lowered QOL, particularly with reference to emotional functioning and school performance. Addressing the needs of this young group has been slow and warrants special attention. Revisiting the risk and resilience factors of adolescents might also inform tailored programs to address the needs of this neglected adolescent population.

Potential Risk Factors for Breast Cancer in Pakistani Women

  • Bano, Raisa;Ismail, Muhammad;Nadeem, Aamer;Khan, Mohammad Haroon;Rashid, Hamid
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.9
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    • pp.4307-4312
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    • 2016
  • Background: Breast cancer is the most common female malignancy worldwide and its incidence is on the rise in Pakistan. The aim of this case-control study was to quantify the association of various risk factors with breast cancer risk among Pakistani women. Materials and Methods: A total of 2,246 women were studied, including 1,238 women with histologically confirmed breast cancer patients and age matched control subjects (N=1008) without breast cancer and other chronic diseases. Subjects were interviewed using a specifically designed questionnaire. Unconditional logistic regression was applied. Subsequent disease-specific mortality was also measured. Results: In this study, majority of the breast cancer patients (69.59%) were in age ranges of 40s and 50s. BMI greater than 25kg/m2 (OR=1.57; 95%CI, 1.26-1.90 and OR=1.60; 95%CI, 1.26-2.03), marital status of unmarried (OR=2.03; 95%CI, 1.69-2.44), lack of breast feeding, smoking (current or ever), lack of physical activity and post-menopausal status were found to have significant positive associations with breast cancer. It was also observed that increased parity reduced the disease risk. A larger number of cases (58.1%) had their right breast affected while 22.8% had other complications as well. Conclusions: This exploratory analysis indicated a number of risk factors to be associated with increased risk of breast cancer. It was also observed that mean age at diagnosis is a decade earlier than in western countries. It is hoped that our findings will facilitate establishment of adequate evidence-based awareness and preventive measures for Pakistani women.

Study on Adopting EDR Report for Traffic Accident Analysis (교통사고분석에서 EDR 기록정보의 채택에 관한 고찰)

  • Park, Jongjin;Park, Jeongman;Lee, Yeonsub
    • Journal of Auto-vehicle Safety Association
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    • v.12 no.3
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    • pp.52-60
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    • 2020
  • Usage of EDR(Event Data Recorder) report for traffic accident analysis is currently increasing due to government regulation of EDR data release. Nevertheless, a lot of investigators simply adopt by comparing the number of ignition cycles(crash) at event to the number of ignition cycles(download) without an exact judgment whether event data occurred by this accident or not. In the EDR report, besides ignition cycles, there are many factors such as event record type, algorithm active(rear/rollover/side/frontal), time between events, event severity status(rollover/rear/right side/reft side/frontal), belt switch circuit status, driver/passenger pretensioner/air-bag deployment, PDOF(Principal Direction of Force) by ΔV to be able to decide whether or not to adopt. also the event data is considered enough to vehicle damaged state, accident situation at the scene of the accident. and there is described in "all data should be examined in conjunction with other available physical evidence from the vehicle and scene" in the CDR(Crash Data Retrieval) report. Therefore many investigators have to decide whether or not to adopt after they consider sufficiently to above factors when they are the traffic accident analysis and investigate the causes of a accident on the adopted event data. In this paper, we report to traffic accident investigators notable points and analysis methods on the basis of thousands of cases and the results of one's own experiment in NFS(National Forensic Service).