• Title/Summary/Keyword: physical evidence

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Palliative Surgery in Two Dogs with Non-Curative Palatal Tumors (두 마리 개에서 완치가 어려운 구개 종양의 완화 수술 적용 증례)

  • Yoon, Hun-Young;Lee, Jung-Ha;Shin, Dong-Wook;Park, Hee-Myung;Jeong, Soon-Wuk
    • Journal of Veterinary Clinics
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    • v.31 no.5
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    • pp.425-429
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    • 2014
  • Two dogs were presented with a history of anorexia, respiratory distress, or epistaxis. On physical examination, the dogs showed difficulty breathing and open-mouth breathing and large masses were found on the hard palate and soft palate. Cardiac arrest happened in case 2 and the dog was stabilized with cardiopulmonary resuscitation and oxygen therapy. Computed tomography demonstrated that the mass occupied the oropharynx, intrapharyngeal ostium, and laryngopharynx including the hard palate and soft palate in case 1. Palliative surgery was decided to improve swallowing and breathing with owner's consent in two dogs. Buccal mucosal flaps were performed for reconstruction of defects using rotational and single-pedicle advancement flaps and bilateral 90 degree transposition flaps in cases 1 and 2, respectively. Histopathology results described the oral masses as amelanotic melanoma in two dogs. The owners reported that there was normal swallowing and breathing at 7 days postoperatively in two dogs. In case 1, recurrent tumor was identified caudal to the hard palate 4 weeks after surgery. The owner did not allow further treatment and the dog became lost to follow-up at 2 months postoperatively. In case 2, there was no clinical or radiographic evidence of a local recurrence or distant metastasis at 3 weeks after surgery. The owner informed that the dog died suddenly with no signs of anything particularly wrong at 7 weeks after surgery.

Black Hair Follicular Dysplasia in a Shih Tzu (Shih Tzu 견에서 발생한 Black Hair follicular Dysplasia 일례)

  • Kim Sung-ryong;Kim Young-in;Seo Jeong-a;Park Ji-won;Jeong A-young;Lee Keun-woo;Oh Tae-ho
    • Journal of Veterinary Clinics
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    • v.22 no.2
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    • pp.157-159
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    • 2005
  • Two-month old male Shih Tzu weighing 2.1 kg was presented with alopecia in black-haired areas of the skin. The hair loss had been present since five weeks of age. There was no history of pruritus on any part of the body. No other symptoms had been recognized. Physical examination found no abnormalities other than hair loss. Skin examination showed marked alopecia of black-haired area of the body. The white areas appeared to have hair growth of normal density and texture. Affected pigmented areas showed no evidence of skin lesions. Skin scraping and fungal culture were negative. Microscopic examination of plucked black hairs showed marked pigment clumping in the remnants of the follicles and were mainly in telogen phase. But white hairs were normal in various stages of hair growth. The diagnosis of black hair follicular dysplasia was made based on the history, alopecia of the pigmented areas, the confinement of abnormalities to dark areas, and the normal unpigmented areas.

The Effect of Stress During Pregnancy on the Skin Barrier of Mice Four Weeks After Birth (임신 중 만성스트레스가 생후 4주 유서(幼鼠)의 피부장벽에 미치는 영향)

  • Cha, Jae-Hoon;Kim, Yoon-Bum
    • The Journal of Korean Medicine
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    • v.30 no.1
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    • pp.83-94
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    • 2009
  • Background and Objectives: The skin barrier protects skin against a harmful environment. Its function includes an antimicrobial barrier as well as a physical barrier. Stress is harmful to the skin barrier and there are many studies on this, but there are few about the effect of stress during pregnancy on the skin barrier of offspring. The aim of this study was to investigate the effect of stress during pregnancy on the skin barrier of offspring by examination with the naked eye, cortisol, weight, TEWL and histologic tests. Materials and Methods: Male hairless mice ten weeks old were coupled with females for three days. After twelve days the females were divided into two groups. We stressed one group and not the other group. The offspring from the non-stressed (N group) and stressed (S group) grew up until four weeks. The S group was exposed to chronic mild stress using the chronic stress model protocol modified method of Wilner and Towell for a week. We made examinations with the naked eye, assessment of cortisol, weight, TEWL, and histologic test to contrast the S group with the N group. Statistical analysis was performed by using Mann-Whitney and Friedman test. Statistical significance was achieved if the probability was less than 5% (p<0.05). Results: 1. By making an examination with the naked eye, S group showed papules, creases and dryness on their skin, but N showed no change compared with normal skin. 2. There was no statistically significant difference between S group and N group in cortisol (p>0.05). 3. There was no statistically significant difference between S group and N group in weight. N group had less weight than S group (p<0.05). 4. There was no statistically significant difference between S group and N group in TEWL (p>0.05). 5. There was no statistically significant difference between S group and N group in TEWL recovery (p>0.05). 6. In TEWL and TEWL recovery, there was statistically significant difference by time between S group and N group (p<0.005). Histologically, S group showed a thicker epidermis and epidermal crest than N group. Conclusions: We found that stress during pregnancy has negative effects on the skin barrier of offspring. Though there were no statistically significant differences between S group and N group in TEWL recovery, we found evidence that the recovery of skin barrier function is interrupted by stress during pregnancy by examination with both the naked eye and histology.

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Experience with the Application of Magnetic Resonance Diagnostic $Analyser^{(R)}$ -A case of reflex sympathetic dystrophy- (자기공명분석기에 의한 반사성 교감신경성 위축증의 치험)

  • Kim, Jin-Soo;Kwak, Su-Dal;Kim, Jun-Soon;Ok, Sy-Young;Cha, Young-Deog;Park, Wook
    • The Korean Journal of Pain
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    • v.6 no.2
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    • pp.275-279
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    • 1993
  • Reflex sympathetic dystrophy is a syndrome characterized by persistent, burning pain, hyperpathia, allodynia & hyperaesthesia in an extremity, with concurrent evidence of autonomic nervous system dysfunction. It generally develops after nerve injury, trauma, surgery, et al. The most successful therapies are directed towards blocking the sympathetic intervention to the affected extremity by regional sympathetic ganglion block or Bier block with sympathetic blocker; other traditional treatments include transcutaneous electrical stimulation, immobilization with cast & splint, physical therapy, psychotherapy, administration of sympathetic blocker, calcitonin, corticosteroid and analgesic agents. The purpose of this report is to evaluate and describe the effects of magnetic resonance following unsatisfactory results with traditional treatments of RSD. A 17 year old female patient, 1 year earlier, had received excision and drainage of pus at the right femoral triangle due to an injury caused by a stone. Afterwards, she experienced burning pain, knee joint stiffness, and muscle dystrophy of the right thigh, especially when standing and walking. Despite a year of number of traditional treatments such as: lumbar sympathetic block, continuous epidural analgesia, transcutaneous electrical stimulation, & administration of predisolone, her pain did not improve. Surprisingly, the patients was able to walk free from pain and difficulty after just one application of magnetic resonance. The patient has been successfully treated with further treatment of two to three times a week for approximately ten weeks. More recently, magnetic resonance has been demonstrated to produce effective results for the relief of pain in a variety of diseases. From our experiences we recognize magnetic resonance as a therapeutic modality which can provide excellent results for the treatment of RSD. It has been suggested that polysynaptic reflex which are disturbed in RSD may be modulated normally on the spinal cord level through the application of magnetic resonance.

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Cause of Pes Anserinus Tenderness (거위발 건 압통의 원인)

  • Kim, Jung-Man;Lee, Dong-Yeob;Koh, In-Jun;Kim, Sang-Il
    • The Journal of Korean Orthopaedic Ultrasound Society
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    • v.2 no.1
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    • pp.13-17
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    • 2009
  • Purpose: The purpose of this study was to know the cause of the tenderness at pes anserinus. Materials and Methods: Out of 24 patients with tenderness at pes anserinus, 23 patients were female and 1 patient was male, and their average age was 65.9 years old. We checked the tenderness at pes anserinus by history taking & physical examniation and then, checked the pes anserinus for the presence of bursitis by US in outpatient clinic. With no evidence of bursitis by US, we injected steroid-lidocaine mixture intraarticularly and checked whether the tenderness disappeared after 2~3 minutes. Results: There was no case with bursitis at pes anserinus by US. The tenderness at pes anserinus diminished in 2-3 minutes after the intraarticular injection of the steroid-lidocaine mixture. After 6 weeks follow up, 16 patients(66.7%) had little or no tenderness at pes anserinus. 8 cases had the recurrence of tenderness recurred, 4 cases underwent arthroscopic operation on the meniscal tear, and 1 case underwent total knee arthroplasty. All cases underwent any operations had the tenderness at pes anserinus disappeared. The others 3 cases did not undergo total knee arthroplasty despite of radiologic obliteration of knee joint adequate for Kellgren-Lawrence grade IV. Conclusion: Without the bursitis at Pes Anserinus, patients the osteoarthritis may have the tenderness due to the referred pain.

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The Changes and Determinants of Cash Holdings of Korean Manufacturing Firms (한국제조기업의 현금보유의 변화와 결정요인에 관한 연구)

  • Shin, Dong-Ryung
    • The Korean Journal of Financial Management
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    • v.25 no.3
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    • pp.1-32
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    • 2008
  • This study examines the changes and determinants of cash to assets ratios(cash ratios) by analyzing 14,016 Korean manufacturing firms sample for the period of $1999{\sim}2004$. The major findings can be summarized as follows. First, the average cash ratios for Korean manufacturing firms have increased from 4.7 percent of 1999 to 5.2 percent of 2004. In addition, the average cash holdings per firm also have increased from 4.3 billion Won to 8.0 billion Won during the same period. However, the capital expenditures relative to cash ratios or operating cash flow have decreased significantly, confirming the notion that physical investment of Korean manufacturing sector has been shrinking recently. Second, in regression tests with panel data, the coefficients of target adjustment variables show the expected negative signs, but coefficients of the deficit of fund variables show the unexpected positive signs. Thus, the evidence seems to be supportive of static tradeoff model of cash holdings. Third, in regression tests to find the determinants of cash ratios, most of the variables show similar results as the previous studies. However, in terms of adjusted coefficient of determination and F-statistic, the firm-characteristic variables suggested by static trade-off theory have more explanatory power than the variables suggested by pecking order theory.

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Current Status of the KMTNet Active Nuclei Variability Survey (KANVaS)

  • Kim, Joonho;Karouzos, Marios;Im, Myungshin
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.1
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    • pp.54.1-54.1
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    • 2016
  • Multi-wavelength variability is a staple of active galactic nuclei (AGN). Optical variability probes the nature of the central engine of AGN at smaller linear scales than conventional imaging and spectroscopic techniques. Previous studies have shown that optical variability is more prevalent at longer timescales and at shorter wavelengths. Intra-night variability can be explained through the damped random walk model but small samples and inhomogeneous data have made constraining this model hard. To understand the properties and physical mechanism of intra-night optical variability, we are performing the KMTNet Active Nuclei Variability Survey (KANVaS). Using KMTNet, we aim to study the intra-night variability of ~1000 AGN at a magnitude depth of ~19mag in R band over a total area of ${\sim}24deg^2$ on the sky. Test data in the COSMOS, XMM-LSS, and S82-2 fields was obtained over 4, 6, and 8 nights respectively during 2015, in B, V, R, and I bands. Each night was composed of 5-13 epoch with ~30 min cadence and 80-120 sec exposure times. As a pilot study, we analyzed data in the COSMOS field where we reach a magnitude depth of ~19.5 in R band (at S/N~100) with seeing varying between 1.5-2.0 arcsec. We used the Chandra-COSMOS catalog to identify 166 AGNs among 549 AGNs at B<23. We performed differential photometry between the selected AGN and nearby stars, achieving photometric uncertainty ~0.01mag. We employ various standard time-series analysis tools to identify variable AGN, including the chi-square test. Preliminarily results indicate that intra-night variability is found for ~17%, 17%, 8% and 7% of all X-ray selected AGN in the B, V, R, and I band, respectively. The majority of the identified variable AGN are classified as Type 1 AGN, with only a handful of Type 2 AGN showing evidence for variability. The work done so far confirms there are more variable AGN at shorter wavelengths and that intra-night variability most likely originates in the accretion disk of these objects. We will briefly discuss the quality of the data, challenges we encountered, solutions we employed for this work, and our updated future plans.

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Phenotypic Variation and Genetic Correlation of Elytra Colored Patterns of Multicolored Asian Lady Beetles, Harmon axyridis (Coleoptera: Coccinellidae) in Korea (우리나라에서 무당벌레 (Harmonia axyridis: Coccinellidae) 의 초시무늬의 표현형 변이와 유전적 상관)

  • Seo, Mi-Ja;Kang, Eun-Jin;Kang, Myong-Ki;Lee, Hee-Jin;Seok, Hee-Bong;Lee, Dae-Hong;Park, Sun-Nam;Yu, Yong-Man;Youn, Young-Nam
    • Korean journal of applied entomology
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    • v.46 no.2
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    • pp.235-249
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    • 2007
  • The multicolored Asian lady beetles (Harmonia axyridis) has characteristic color patterns, which show great variability within species. Up to now, it has been well known that main factors affected on individual color pattern variations in the population of H axyridis are external, physical, and environmental characteristics. Indeed, there is as yet no evidence to indicate whether the variation is genetic or environmental factors. Also the factors which produce this variation are unknown in this species, although it is suspected that much of the variation is under genetic control. However, the genetic relationships among many of color types were investigated by observing the progeny of each particular pairs. It is worth mentioning a few particular breeding cases to illustrate certain facets of variability, and to indicate examples suitable for genetic analysis of the color pattern variation.

Evaluation of Visual Perception in Smoking Cessation Websites and Construction of Antismoking Website

  • Lee, Yoon-Hyeon;Shin, Soon-Ho
    • Korean Journal of Health Education and Promotion
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    • v.20 no.4
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    • pp.95-109
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    • 2003
  • Tobacco use is the most readily preventable cause of premature death; it is a worldwide problem, with a significant impact on heath and well-being. In order to design an effective tobacco education program, it is important to understand smoking patterns and the underlying factors associated with smoking in different generations such as adults or young people. Despite a general decline in the prevalence of regular smoking among adults, recent surveys commissioned by the Ministry Heath & Welfare for the Republic of Korea have shown no evidence of any decline in smoking rates among young women and adolescents. The Republic of Korea has the highest adult male smoking percentage (65.1%) in the world and smoking in adolescents is still an increasing trend. Smoking in adolescents and young women is especially more dangerous, thus health education of anti-smoking directed at these groups is an important area that will benefit from using internet content that they can easily access. The purpose of this study is the evaluation of visual perception and effectiveness analysis in smoking cessation websites in promoting smoking cessation in adolescents and young women through Internet content. As a result of this project, at first we evaluated the Internet content of cyber smoking cessation programs by the evaluation criteria of web design interface. The Internet site of http://nosmokeguide.or.kr received the most superior evaluation in the domestic Internet content for smoking cessation and the Internet site of the National Center for Tobacco-Free Kids received the most superior evaluation in the foreign Internet content for smoking cessation. This evaluation was surveyed by an expert in Internet content and user. Secondly, we developed the Internet content for cyber smoking cessation program, namely, "Dr. Smoking" that contained several menus and a database regarding anti-smoking designed in accordance with the results of this evaluation. The domain address of Dr. Smoking is http://www.dmosmoking.com and our webpage has assorted kinds of news, information, self-diagnosis, prescription, consulting, a no-smoking mall etc. In conclusion, this project is designed to develop Internet content for the most effective smoking cessation program and to contribute to eliminating smoking from our society. We also will try to develop and upgrade this web-site in order to help a smoker who want to quit smoking and diminish the physical and socioeconomic harm from smoking.m smoking.

Qualitative Analysis of Medical Usage Patterns of Medical Aid Patients (의료급여환자의 의료이용행태에 관한 질적 분석)

  • Park, Young-Hee;Lee, Yong-Jae
    • The Journal of the Korea Contents Association
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    • v.17 no.9
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    • pp.39-49
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    • 2017
  • This was a qualitative study on medical aid patients to understand the cause and process of statistical difference of health service utilization between medical aid and health insurance patients. The main results were the following; 1) There was few overuse of health service in medical aid patients. The reason of heavy utilization was mainly due to the complicated disease. Some of them were considered to overuse physical therapy and oriental acupuncture. 2) In case of medical aid patients, medical cost was paid by their welfare benefit of government or by the support of family or neighbors. They usually could not adequately use the services of uninsured benefit or large hospitals due to the cost. Some patients just endured the pain. There was still discrimination for medical aid patients in some medical institutions. 3) The health officials and institutions did not provide sufficient information to medical aid patients about the policy of medical cost support. 4) Health policies, such as selective clinic system, medial aid case management, approval of extended care, were considered to contribute in preventing unnecessary use of health service. However, this might limit adequate use of medical aid service. In conclusion, there is little evidence of overuse of health service for medical aid patients, which is different from the previous studies. A new plan is necessary, because medical aid patients thought that the necessary health service was not accessible to them.