• Title/Summary/Keyword: phase-contrast

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Microstructural Changes of $SiO_2-Si$ During Liquid-Phase Sintering (액상소결단계에서 $SiO_2-Si$의 미세조직 변화)

  • 강대갑;정충환
    • Journal of the Korean Ceramic Society
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    • v.31 no.4
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    • pp.443-447
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    • 1994
  • Compacts of mixed SiO2-Si powder were liquid phase sintered at 145$0^{\circ}C$ for up to 60 min in a hydrogen atmosphere. In contrast to the conventional microstructures of liquid phase sintered materials, the specimens showed that the solid phase of SiO2 formed a matrix while the liquid phase of Si was the dispersed in the solid matrix. The dispersion of liquid Si pockets was attributed to the high wetting angle of liquid Si on solid SiO2. Because of relatively high solubility of SiO2 in liquid Si at 145$0^{\circ}C$, SiO2 particles accommodated their shape via a solution-reprecipitation process. The liquid Si pockets grew by coalescing with their neighbour pockets. In the latter stage of the sintering, plate-shape grains appeared in the liquid Si pockets. The grains were SiO2 phase precipitated from the liquid Si which was oversaturated with oxygen during cooling to room temperature. By the formation and subsequent removal of the gaseous SiO phase due to the reaction between SiO2 and Si, the specimens became porous.

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Effect of Saline Flush on the Enhancement of Vascular and Liver via Saphenous Vein for Abdominal CT in Dogs

  • Kim, Song Yeon;Hwang, Tae Sung;An, Soyon;Hwang, Gunha;Go, Woohyun;Lee, Jong Bong;Lee, Hee Chun
    • Journal of Veterinary Clinics
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    • v.38 no.3
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    • pp.135-142
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    • 2021
  • The aim of this study was to evaluate the contrast effect if a saline flush following low-volume contrast medium bolus improves vascular and parenchymal enhancement using a saphenous vein in abdominal CT for small animals. Six clinically healthy beagle dogs underwent abdominal contrast-enhanced CT. They were divided into nine groups (each group, n = 6), according to the volume of contrast medium 1, 2, and 3 mL/kg, and volume of the saline solution 0, 5, and 10 mL. Dynamic CT scanning was performed at the hepatic hilum level. The maximum contrast enhancement, time to maximum enhancement, and time to equilibrium phase were calculated from the time attenuation curves. Mean attenuation values for all groups were measured in the aorta, portal vein, and liver. After contrast enhancement, grading of image quality regarding surrounding artifacts and evaluation of the hepatic hilum structures was performed. For comparison of the effect of the contrast material and saline solution doses, differences in mean attenuation values between the contrast medium 2 mL/kg without saline flush group and the remaining groups, and between contrast medium 3 mL/kg without saline flush group and the remaining groups, were analyzed for statistical significance. There were no significant differences between with and without saline flushing at the same contrast medium dose groups. There were no significant differences in peak values between the 3 mL/kg dose of contrast medium alone and the 2 mL/kg dose of contrast medium with saline solution flush. However, there was a significant difference in peak values between the 3 mL/kg dose of the contrast medium without the saline flush group and the 2 mL/kg dose of the contrast medium alone group. Grades of the artifacts were not significantly different in the saline flush regardless of the dose of the contrast medium. Using 2 mL/kg of contrast medium with saline solution flush resulted in similar liver parenchyma attenuation, compared with using 3 mL/kg of contrast medium without saline solution flush. In CT evaluation of hepatic parenchymal diseases, using 2 mL/kg of contrast medium with saline solution flush may yield decreased risk of contrast nephropathy and cost-saving.

System Design and Evaluation of a Compact and High Energy X-ray Talbot-Lau Grating Interferometer for Industrial Applications

  • Lee, Seho;Oh, Ohsung;Kim, Youngju;Lee, Seung Wook;Kim, Insoo;Kim, Jinkyu
    • Journal of the Korean Physical Society
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    • v.73 no.12
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    • pp.1827-1833
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    • 2018
  • X-ray grating interferometry has been an active area of research in recent years. In particular, various studies have been carried out for the practical use of the x-ray grating interferometer in medical and industrial fields. For the commercialization of the system, it needs to be optimized for its application. In this study, we have developed a prototype of the compact high energy x-ray grating interferometer of which the high effective energy and compactness is of our primary feature of design. We have designed the Talbot-Lau x-ray interferometer in a symmetrical geometry with an effective energy of 54.3 keV. The system has a source-to-analyzer grating distance of 788.4 mm, which is compact enough for a commercial product. In a normal operation, it took less than ten seconds to acquire a set of phase stepping images. The acquired images had a maximum visibility of about 15%, which is relatively high compared with the visibilities of the other high-energy grating interferometric systems reported so far.

Synchrotron Radiation Imaging of Tissues Using Phase Contrast Technique (방사광 위상차 현미경을 이용한 생체조직의 미세구조 영상)

  • Kang, Bo-Sun;Lee, Dong-Yeol;Kim, Ki-Hong
    • Journal of the Korean Society of Radiology
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    • v.2 no.2
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    • pp.23-30
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    • 2008
  • X-ray microscopy with synchrotron radiation(SR) might be a useful tool for novel x-ray imaging in the clinical and laboratory settings. Microscopically, it enables us to observe detailed structure of animal organs samples with a great magnification power and an excellent resolution. The phase contrast mechanisms in image by X-ray are described. The phase-contrast X-ray imaging with SR from in-vivo and in-vitro mouse tail, rat nerve and rat lung were obtained with an 8 KeV monochromatic beam. The visual image was magnified using 10x microscope objective lens and captured using an digital CCD camera. The results showed more structural details and high resolution images with SR imaging system than conventional X-ray radiography system. The SR imaging system may have a potential for imaging in biological researches, material applications and clinical radiography.

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Establishment of Injection Protocol of Test Bolus for Precise Scan Timing in Canine Abdominal Multi-Phase Computed Tomography

  • Choi, Sooyoung;Lee, In;Choi, Hojung;Lee, Kija;Park, Inchul;Lee, Youngwon
    • Journal of Veterinary Clinics
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    • v.35 no.3
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    • pp.93-96
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    • 2018
  • This study aimed to establish an injection protocol to determine the precise CT scan timing in canine abdominal multi-phase CT using the test bolus method. Three dynamic scans with different contrast injection parameters were performed using a crossover design in eight normal beagle dogs. A contrast material was administered at a fixed dose of 200 mg iodine/kg as a test bolus for dynamic scans 1 and 2, and 600 mg iodine/kg as a main bolus for dynamic scan 3. The contrast materials were administered with 1 ml/s in dynamic scan 1, and 3 ml/s in dynamic scan 2 and 3. The mean arrival time to the appearance of aortic enhancement in dynamic scan 3 was similar to that in dynamic scan 2, and different significantly to that in dynamic scan 1. The mean arrival time to the peak aortic and pancreatic parenchymal enhancement in dynamic scan 3 was similar to that in dynamic scan 1, and different significantly to that in dynamic scan 2. In multi-phase CT scan, a test bolus should be injected with the same injection duration of a main bolus, to obtain the precise arrival times to peak of arterial or pancreatic parenchymal enhancement.

Analytical Variability of Airborne Man-made Mineral Fibers by Phase Contrast Microscopy (위상차 현미경법에 의한 인조광물섬유 분석 변이)

  • Shin, Yong Chul;Yi, Gwang Yong;Kim, Boowook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.22 no.2
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    • pp.134-139
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    • 2012
  • Objectives: This study was conducted to study the analytical variability of A & B counting rules in counting using a phase contrast microscope airborne fibers collected on filters in man-made mineral or vitreous fibers (MMMFs) industries. Methods: Fibers in filters were counted using A & B rules of NIOSH Method 7400. Intra-counter and inter-counter variations by fiber type and density were obtained. The types of MMMFs analyzed were glass wool fiber, rock wool fiber, slag wool fiber, and refractory ceramic fibers. The densities of fibers classified were <20 $fibers/mm^2,$ 20 - <50 $fibers/mm^2$, 50 - <100 $fibers/mm^2,$ and ${\geq}100$ $fibers/mm^2,$ respectively. Results: Intra-counter relative standard deviations by rule A were 0.084, 0.102, 0.071 for glass wool fibers, rock wool fibers and refractory ceramic fibers, and those by rule B were 0.139, 0.120 and 0.142, respectively. Inter-counter relative standard deviations by rule A were 0.281, 0.296, 0.180 for glass wool fibers, rock wool fibers and refractory ceramic fibers, and those by rule B were 0.396, 0.337 and 0.238, respectively. Conclusions: Intra-counter variation was not different significantly among fiber types (p>0.05), but B rule variation for ceramic fibers approximately 2 times greater than corresponding A rule estimates, and intra-counter and inter-counter variations were higher in the low fiber density.

Synthesis and Characterization of a Receptor-Targeting Contrast Agent

  • Yang, Taegyun;Park, Ji-Hyung;Lee, Seung-Cheol;Kim, Cheol-Su;Cho, Jee-Hyun;Lee, Chul-Hyun;Cheong, Chae-Joon
    • Journal of the Korean Magnetic Resonance Society
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    • v.7 no.1
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    • pp.46-54
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    • 2003
  • We synthesized a contrast agent for MRI that is capable of binding to the ABP-1 receptor and enhancing the contrast of the targeted cells. We used a lysine dendrimer (G=3)DTPA[Gd] as the contrast agent and synthesized a biotinylated polyclonal antibody for ABP-1 as the first antibody. Lysine dendrimers were prepared using the solid phase peptide synthesis method.$^3$ Amino-terminated lysine dendrimers were then coupled to DTPA using the anhydride method. Gd was complexed with the DTPA-lysine dendrimer in an acidic solution of 3 eq GdCl$_3$ to one of DTPA. The lysine dendrimer-DTPA[Gd] and avidin were conjugated in MES solution, pH 6.0, using EDC as the coupling reagent. The biotin-avidin system was used to link the polyclonal antibody and contrast agent. K562 cells were used for imaging.

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Hepatic Cavernous Hemangioma in Cirrhotic Liver: Imaging Findings

  • Jeong-Sik Yu;Ki Whang Kim;Mi-Suk Park;Sang-Wook Yoon
    • Korean Journal of Radiology
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    • v.1 no.4
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    • pp.185-190
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    • 2000
  • Objective: To document the imaging findings of hepatic cavernous hemangioma detected in cirrhotic liver. Materials and Methods: The imaging findings of 14 hepatic cavernous hemangiomas in ten patients with liver cirrhosis were retrospectively analyzed. A diagnosis of hepatic cavernous hemangioma was based on the findings of two or more of the following imaging studies: MR, including contrast-enhanced dynamic imaging (n = 10), dynamic CT (n = 4), hepatic arteriography (n = 9), and US (n = 10). Results: The mean size of the 14 hepatic hemangiomas was 0.9 (range, 0.5-1.5) cm in the longest dimension. In 11 of these (79%), contrast-enhanced dynamic CT and MR imaging showed rapid contrast enhancement of the entire lesion during the early phase, and hepatic arteriography revealed globular enhancement and rapid filling-in. On contrast-enhanced MR images, three lesions (21%) showed partial enhancement until the 5-min delayed phases. US indicated that while three slowly enhancing lesions were homogeneously hyperechoic, 9 (82%) of 11 showing rapid enhancement were not delineated. Conclusion: The majority of hepatic cavernous hemangiomas detected in cirrhotic liver are small in size, and in many, hepatic arteriography and/or contrast-enhanced dynamic CT and MR imaging demonstrates rapid enhancement. US, however, fails to distinguish a lesion of this kind from its cirrhotic background.

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Influence of Phase Angle Characteristics to Energy Input of Earthquake Ground Motions (지진동의 입력에너지에 대한 위상각 차이의 영향)

  • Woo, Woon-Taek;Park, Tae-Won;Jung, Ran
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2003.04a
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    • pp.243-249
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    • 2003
  • The characteristics of harmonic phase angles and phase angle differences contained in earthquake ground motions such as El Centre 1530 NS, Taftl 1952 NS, Hachinohe 1968 NS and Mexico 1985 are figured, which have been mostly overlooked in contrast with the importance placed on harmonic amplitudes. And, energy input spectrum of structures excited by such an earthquake motion is expressed with smoothed Fourier amplitude spectrum. In dynamic response analysis, there must be earthquake ground accelerations which contain the phase angle, the phase angle difference and energy input spectrum characteristics of the zone considered to be constructed building structures. To make clear the importance of phase angle differences, 4-earthquake ground motions are normalized by 200 gal and energy input spectrum characteristics of normalized 4-earthquake ground motions are compared.

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Nonlinear Response and Phase Angle Characteristics of Earthquake Ground Motions (지진동의 위상 특성과 비선형 응답)

  • Woo, Woon-Taek;Park, Tae-Won;Jung, Ran
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2002.10a
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    • pp.497-504
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    • 2002
  • The characteristics of harmonic phase angles and phase angle differences contained in earthquake ground motions such as El Centre 1940 NS, Taft1 1952 NS, Hachinohe 1968 NS and Mexico 1985 are figured, which have been mostly overlooked in contrast with the importance placed on harmonic amplitudes. Recently, performance based design method is used for seismic design and seismic retrofitting, which needs nonlinear response analysis, there must be earthquake ground accelerations which contain the phase angle and the phase angle difference characteristics of the zone considered to be constructed building structures. To make clear the importance of phase angle differences, 4-earthquake ground motions are normalized by 200 gal and nonlinear response characteristics of normalized 4-earthquake ground motions are compared.

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