• 한국산학기술학회논문지
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• 제17권8호
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• pp.605-614
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• 2016

본 연구는 지역사회에 거주하는 경도인지장애로 진단받은 노인들을 대상으로 작업회상치료(ORT)를 적용한 후 인지기능, 신체적 건강상태, 의사소통과 상호작용 기술 및 우울감에 미치는 효과를 알아보고자 실시하였다. 연구 대상자는 경도인지장애 진단받은 만 65세 이상의 노인으로 YW 보건소에 등록되어 정기적으로 내원하는 자로 실험군과 대조군으로 임의로 할당하였고 실험군에게 1주일에 1회, 1시간씩 총 8회기 작업회상치료를 실시하였다. 작업회상치료 프로그램은 대상자들의 개별 인터뷰를 통해 공통으로 경험한 사건 및 활동을 확인하고, 선행 연구에서 사용된 프로그램들에 대한 문헌을 고찰하여 종합한 후 내용타당도 검증을 실시하였다. 작업회상치료가 미치는 효과에 대한 전 후간 차이 검증은 paired t-test, 중재 후 실험군과 대조군 간의 변화량 차이 검증은 Mann-Whitney U 검정을 실시하였다. 그 결과 실험군(n=9)이 대조군(n=9)에 비해 인지기능, 신체적 건강상태, 의사소통과 상호작용 기술 및 우울감에서 유의미한 향상을 보였다. 이로써, 작업회상치료(ORT)는 경도인지장애 노인의 치매를 예방하고 건강 유지 및 증진에 효과적인 비약물적 치료 방법의 하나로 적극 활용될 수 있기를 기대한다.

• The Korean Journal of Pain
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• 제34권4호
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• pp.427-436
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• 2021

Background: Pharmacological and non-pharmacological therapies have been used to treat patients with chemotherapy-induced peripheral neuropathy (CIPN). However, the effect of therapies in cancer patients has yet to be investigated comprehensively. We hypothesized that cyclic thermal therapy would improve blood flow and microcirculation and improve the symptoms driven by CIPN. Methods: The criteria of assessment were blood volume in region of interest (ROI) in the images, and European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 questionnaire scores. The blood volume was quantified by using red blood cell (RBC) scintigraphy. All patients were treated 10 times during 10 days. The thermal stimulations, between 15° and 41°, were repeatedly delivered to the patient's hands. Results: The total score of the questionnaires, the score of questions related to the upper limbs, the score of questions closely related to the upper limbs, and the score excluding the upper limbs questions was decreased. The blood volume was decreased, and the variance of blood volume was decreased. During cooling stimulation, the blood volume was decreased, and its variance was decreased. During warming stimulation, the blood volume was decreased, and its variance was decreased. Conclusions: We suggest that cyclic thermal therapy is useful to alleviate CIPN symptoms by blood circulation improvement. RBC scintigraphy can provide the quantitative information on blood volume under certain conditions such as stress, as well as rest, in peripheral tissue.

• The Korean Journal of Pain
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• 제33권2호
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• pp.121-130
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• 2020

Background: Transcutaneous electrical nerve stimulation (TENS), manual acupuncture (MA), and spinal cord stimulation (SCS) are used to treat a variety of pain conditions. These non-pharmacological treatments are often thought to work through similar mechanisms, and thus should have similar effects for different types of pain. However, it is unclear if each of these treatments work equally well on each type of pain condition. The purpose of this study was to compared the effects of TENS, MA, and SCS on neuropathic, inflammatory, and non-inflammatory pain models. Methods: TENS 60 Hz, 200 ㎲, 90% motor threshold (MT), SCS was applied at 60 Hz, an intensity of 90% MT, and a 0.25 ms pulse width. MA was performed by inserting a stainless-steel needle to a depth of about 4-5 mm at the Sanyinjiao (SP6) and Zusanli (ST36) acupoints on a spared nerve injury (SNI), knee joint inflammation (3% carrageenan), and non-inflammatory muscle pain (intramuscular pH 4.0 injections) in rats. Mechanical withdrawal thresholds of the paw, muscle, and/or joint were assessed before and after induction of the pain model, and daily before and after treatment. Results: The reduced withdrawal thresholds were significantly reversed by application of either TENS or SCS (P < 0.05). MA, on the other hand, increased the withdrawal threshold in animals with SNI and joint inflammation, but not chronic muscle pain. Conclusions: TENS and SCS produce similar effects in neuropathic, inflammatory and non-inflammatory muscle pain models while MA is only effective in inflammatory and neuropathic pain models.

• 대한통합의학회지
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• 제9권2호
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• pp.35-41
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• 2021

Purpose : It is necessary to demonstrate the effect of non-invasive and non-pharmacological interventions such as manual therapy and therapeutic exercise for the management of nonspecific neck pain. In the present study, we aimed to investigate the efficacy of myofascial release therapy plus therapeutic exercise for disability owing to neck pain and quality of life in individuals with nonspecific neck pain. Methods : Eighteen participants with nonspecific neck pain were randomly allocated to intervention (n=9) and control groups (n=9). The intervention group received a myofascial release therapy for 20 min and performed neck stabilization exercises for 30 min twice a week for 4 weeks. The control group performed neck stabilization exercises for 30 min twice a week for 4 weeks at the same time points as the intervention group. Disability owing to neck pain and quality of life were quantified using the neck disability index (NDI) and the Korean version of the World Health Organization Quality of Life Brief Version (WHOQOL-BREF), respectively. NDI and WHOQOL-BREF were assessed before and after intervention. Results : The disability owing to neck pain significantly changed between the groups over time (total score of NDI, p=.049). There were significant time and group interactions in pain (pain intensity of NDI, p=.035) and concentration (concentration of NDI, p=.049). Personal care, lifting, reading, headaches, work, driving, sleeping, and recreation did not show significant improvement between the groups over time. Total score, overall quality of life and general health, physical health domain, psychological domain, social relationships domain, and environmental domain quantified by WHOQOL-BREF did not show significant improvements between the groups over time. Conclusion : These results suggest the clinical use of myofascial release therapy in addition to therapeutic exercise for the management of nonspecific neck pain. Further studies are needed to generalize the findings of this study.

• 한국산학기술학회논문지
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• 제17권3호
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• pp.638-651
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• 2016

본 연구는 중년여성을 대상으로 한 비약물적 우울중재연구를 고찰하고 그 효과를 탐색하기 위해 수행되었다. 체계적 문헌고찰은 국내 데이터베이스인 RISS, KISS, DBPia의 온라인 검색을 통해 2006년부터 2015년 9월까지 국내 학술지에 게재된 연구 논문을 대상으로 하였으며. 자료 검색어는 중년여성과 우울, 폐경기와 우울, 갱년기와 우울로 하였다. 그 결과, 280편이 검색되었고, PICOTS-SD에 따라 최종 12편이 분석에 이용되었다. 그 중 4편은 간호학 분야 연구였고, 6편은 무작위 배정이 이루어진 무작위 대조군 실험연구였다. 비약물적 우울중재는 에어로빅 등 신체적 활동을 포함하는 형태가 4편으로 가장 많았고, 웃음요법과 단전 등 명상 각각 3편, 아로마 마사지와 상담 각각 2편, 미술요법이 1편으로 나타났고, 복합중재가 적용된 논문은 3편이었다. 중재 프로그램의 1회 적용 시간은 20분에서 120분, 중재 적용 기간은 2주에서 24주, 총 중재 회기는 8회에서 72회로 나타났고, 이들 프로그램은 우울뿐만 아니라 비만과 관련된 신체적 측면과 불안, 삶의 질, 삶의 만족도 등 사회 심리적 변수에 유의한 영향을 주는 것으로 나타났다.

• 동의신경정신과학회지
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• 제27권4호
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• pp.261-274
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• 2016

Objectives: To determine the general characteristics of clinical studies about Hwabyung and assess their limitations and alternatives. Methods: Clinical studies that examined the effects of traditional Korean medicine intervention on Hwabyung were included in this study. A systematic search of English, Chinese, Japanese, and Korean databases was performed. The characteristics of included articles were described and those articles were assessed by Risk of Bias (RoB) tool or Risk of Bias for Nonrandomized Studies (RoBANS) tool. Results: Sixteen articles were selected from 1,826 articles. Most clinical studies about Hwabyung were published in Korea. The number of conducted trials was insufficient. The prevailing study design was randomized controlled trial. Traditional Korean medicine intervention used in the trials were acupuncture, herbal medicine, counselling, meditation, emotional freedom technique (EFT), music therapy, art therapy, and multi intervention program. Herbal medicine study used placebo as control while non-pharmacological intervention study mostly used no treatment as control. Most of the trials were supported by the government. Therefore, financial conflict of interest might not exist for results. We judged that some studies had a high risk of bias. In general, most of the studies with a high risk of bias were non-pharmacological intervention studies, and the risk of bias was mainly due to lack of blinding. Conclusions: More clinical studies of Hwabyung are needed. There are some issues about a suitable comparison and effective blinding strategy for non-pharmacological study. Improving methodological quality is required.

• The Journal of Advanced Prosthodontics
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• 제9권3호
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• pp.224-231
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• 2017

PURPOSE. This study was designed to evaluate the teeth and dental implants during dental maintenance therapy over 3 years in different conditions after periodontal and dental prosthetic treatment. MATERIALS AND METHODS. 166 patients received maintenance therapy. 59 patients were treated with 2% minocycline-HCl ointment as local drug delivery (LDD) (L group) and 107 patients were treated without LDD (NL group). Clinical data was collected in maintenance period for evaluation. Patients were classified into groups depending on the application of LDD with maintenance therapy, the type of dental treatment before maintenance period (Pre-Tx), the frequency (F-MT), and regularity (R-MT) of maintenance therapy. RESULTS. The numbers of lost teeth (N-teeth, P=.003) and newly placed dental implants (N-implants, P=.022) are significantly different according to Pre-Tx. F-MT among patients who received surgical dental treatment before maintenance period showed statistical differences in N-teeth (P=.041), but not in N-implants (P=.564). All of the patients in L group showed high F-MT (F-MT1). In NL group, there were no statistical differences in N-teeth or N-implants according to F-MT or R-MT. In F-MT1 group, application of LDD made N-teeth significantly different from both Pre-Tx groups while no significant difference could be found in N-implant. Independent t-test and one-way ANOVA were selected for statistical analysis. CONCLUSION. The regular maintenance therapy and LDD can be effective for teeth during maintenance period. It is not only pharmacological efficacy in decreasing bacterial species that makes LDD a useful adjunct. Application of LDD also motivates patients to take adequate check-ups in the aspects of both frequency and regularity.

• Journal of Oral Medicine and Pain
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• 제31권2호
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• pp.177-183
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• 2006

관절강세정술은 통상의 보존적 치료법에 실패한 측두하악관절장애 환자에서 합병증의 위험성이 높은 침습적인 외과적 수술법에 대신하여 첫 번째로 고려될 수 있는 치료법이다. 본 증례의 환자들은 측두하악관절의 비정복성 관절원판변위로 진단되어 지속적인 교합안정장치치료, 행동요법치료, 물리치료, 약물치료 등의 보존적 치료에도 불구하고 심한 관절동통과 하악운동범위의 제한을 호소하였다. 따라서 보존적 치료법에 잘 반응하지 않는다고 판단하여 반복적인 관절강세정술을 시행하였고, 시술직후 유의한 동통감소, 하악운동범위의 개선과 함께 양호한 치료경과를 나타냈다. 관절강세정술은 최소의 침습성을 지니는 가장 보존적인 외과적 술식으로서 통법의 보존적 치료에 반응하지 않는 비정복성 관절원판변위 환자를 상기 증례와 같이 적절히 선택한다면 측두하악관절장애의 동통과 기능제한에 효과적인 보조적 치료법이라고 생각된다.

• 동의생리병리학회지
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• 제29권3호
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• pp.203-217
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• 2015

Scolpendra subspinipes (centipede) is pungent in flavor, activates the channels to stop pain, and, removes toxins and resolves masses. So it has been used as a folk remedy. We researched folk remedies which used centipede as a single medicine and results of its prior clinical and experimental study, and figured out that centipedes are effective on ulcerative disease, herpes zoster, clavus, insect bite, inflammatory disease, furunculus, pain disease by external therapy, and oral administration is effective on anti-cancer such as hepatoma and uterine cancer, cerebrovascular disease, inhibition of atherosclerosis, sedation of central nervous system, antipyretic action, and anti-inflammation, and centipede Herb-Acupuncture is effective on inflammatory disease and pain disease. Centipede preparation materials for external therapy were sesame oil, perilla oil, vinegar, salt, and, burnt alum. Fumigation of centipede treated paronychia, pertussis, and hemorrhoids. For the external therapy, the way of centipede powder mixing with other materials has been used. It is needed that we use dusted powder to make skin absorb its ingredients more easily, and we study intensely minor ingredients to make centipede components absorbed more effectively and do pharmacological action. Also, fumigation, a kind of another external therapy, is considered to be effective treatment of upper respiratory infection like pertussis, so it needs an in-depth study on centipede fumigation.

• Physical Therapy Rehabilitation Science
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• 제7권2호
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• pp.88-93
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• 2018

Objective: Elevated cholesterol levels contribute to changes of the arterial endothelial permeability. Hyperlipidemia promotes atherosclerosis and is associated with an increased risk of stroke incidence. The purpose of this study was to investigate the effects of having a history of hyperlipidemia prior to a stroke incidence on postural balance, anticipatory dynamic postural control, gait endurance and gait performance in individuals with hemiparetic stroke. Design: Cross-sectional study. Methods: Fifty-two adults who were diagnosed with stroke 6 months ago or more were enrolled in this study. They were divided into two different groups according to hyperlipidemia history before stroke. All participants were assessed with the Activities-specific into Balance Confidence (ABC) scale, Berg Balance scale (BBS), Dynamic Gait Index (DGI), Timed Up and Go test (TUG), and the 6-minute walk test (6MWT). An independent t-test was used to analyze the difference between the hyperlipidemia group and non-hyperlipidemia group. Results: After analysis, the BBS, TUG, and 6MWT scores were significantly different between the hyperlipidemia and non-hyperlipidemia group, but not the ABC and DGI scores. Conclusions: The results of this study show that having a history of hyperlipidemia before stroke affects static and dynamic postural balance performance, anticipatory dynamic postural balance, and gait endurance in individuals with chronic hemiparetic stroke. Based on the results of this study, we also suggest treatment for hyperlipidemia should be implemented throughout the therapeutic interventions, such as pharmacological or exercise programs, in order to restore the physical function of stroke survivors.