• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.103-103
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• 2002

목적：자화율 대조법을 사용한 관류 영상에서 동시획득 $T_{1}T_{2}^{*}$ 강조 경사 자장 펄스열을 사용하여 Gd-DTPA에 의한 $T_{1}T_{2}^{*}$ 감소 효과를 동시에 획득하여 종양의 치료 효과, 판정에 중요한 기준을 제시할 수 있는 정확한 관류 정보를 얻고자 한다. 대상 및 방법： Gd-DTPA에 의한 $T_{1}T_{2}^{*}$ 감소 효과를 동시에 획득하기 위하여 기존의 이중 경사자장 펄스열을 수정, 동시획득 $T_{1}T_{2}^{*}$ 강조 경사자장 펄스열을 개발하였고, 시간 해상도를 높이기 위하여 key-hole 방법을 사용하였다. 고정 phantom으로 Sephadex를 다양한 농도의 Gd-DTPA 용액에 swelling하여 사용하였고, 관류 phantom으로는 Sephadex와 Dialyzer를 사용하였다. Sephadex는 swelling 하였을 때 $T_1$, $T_2$값이 생체 조직의 값과 비슷하고, 물을 관류시킬 수 있어 생체 모형에 적합한 phantom이다 .관류 phantom은 정량 펌프에 연결하여 사용하였다. Sephadex 관류 phantom에서는 분당 약 4$m\ell$ 속도로 관류시키면서 25 mM Gd-DTPA을 0.1$m\ell$ 일시 주입하여 관류 방향에 수직인 coronal 영상을 약 15분 동안 얻었다. 투과도를 구하기 위한 phantom으로는 hollow fiber type Dialyzer를 사용하였고, in vivo에서 1차 관류 이후에 현관 밖에서의 Gd농도가 높고 혈관 내부의 농도가 낮은 상태를 만들기 위하여 fiber 바깥쪽으로 500 mM Gd-DTPA 2 ml를 미리 넣어두고 fiber 내부로 이보다 낮은 농도의 Gd 용액을 관류시키면서 약 1시간동안 영상을 얻었다. 관류 영상에서 $T_1$/$T_{2}^{*}$ 감소 효과를 구분하여 구한 $\DeltaR_1$, $\DeltaR_2$ 곡선의 적분값으로부터 관류량을 구하고, 2 구획 모델을 적용하여 투과도를 구했다.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.127-127
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• 2002

목적： 자화율 대조법을 사용한 관류 영상에서 동시획득 $T_{1}{/}T_{2}^{*}$ 강조 경사 자장 펄스열을 사용하여 Gd-DTPA에 의한 $T_{1}{/}T_{2}^{*}$ 감소 효과를 동시에 획득하여 종양의 치료 효과, 판정에 중요한 기준을 제시할 수 있는 정확한 관류 정보를 얻고자 한다. 대상 및 방법： Gd-DTPA에 의한 $T_{1}{/}T_{2}^{*}$ 감소 효과를 동시에 획득하기 위하여 기존의 이중 경사자장 펄스열을 수정, 동시획득 $T_{1}{/}T_{2}^{*}$ 강조 경사자장 펄스열을 개발하였고, 시간 해상도를 높이기 위하여 key-hole 방법을 사용하였다. 고정 phantom으로 Sephadex를 다양한 농도의 Gd-DTPA 용액에 swelling하여 사용하였고, 관류 phantom으로는 Sephadex와 Dialyzer를 사용하였다. Sephadex는 swelling 하였을 때 $T_1$, $T_2$값이 생체 조직의 값과 비슷하고, 물을 관류시킬 수 있어 생체 모형에 적합한 phantom이다. 관류 phantom은 정량 펌프에 연결하여 사용하였다. Sephadex 관류 phantom에서는 분당 약 4$m\ell$ 속도로 관류시키면서 25 mM Gd-DTPA을 0.1$m\ell$ 일시 주입하여 관류 방향에 수직인 coronal 영상을 약 15분 동안 얻었다. 투과도를 구하기 위한 phantom으로는 hollow fiber type Dialyzer를 사용하였고, in vivo에서 1차 관류 이후에 혈관 밖에서의 Gd 농도가 높고 혈관 내부의 농도가 낮은 상태를 만들기 위하여 fiber 바깥쪽으로 500mM Gd-DTPA 2$m\ell$를 미리 넣어두고 fiber 내부로 이보다 낮은 농도의 Gd 용액을 관류시키면서 약 1시간동안 영상을 얻었다. 관류 영상에서 $T_{1}{/}T_{2}^{*}$ 감소 효과를 구분하여 구한 $\Delta{R}_{1}$, $\Delta{R}_{2}^{*}$ 곡선의 적분값으로부터 관류량을 구하고, 2 구획 모델을 적용하여 투과도를 구했다.

• Journal of Biomedical Engineering Research
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• v.43 no.4
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• pp.271-279
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• 2022

Functional cosmetics containing various ingredients that improve skin health are currently being developed. In addition, technologies that help increase the absorption rate of such cosmetics have recently gained significant attention. Sonophoresis is a method to increase the transdermal absorption of cosmetics using ultrasound. A skin-mimicking phantom was fabricated using polydimethylsiloxane, Strat-M^TM membrane, and thermochromic pigments. Gel-type cosmetics used in skin mask packs and epidermal-growth-factor-based nano-cosmetics were tested for their absorption rates at ultrasound frequencies of 1, 3, and 10 MHz in the single frequency mode, and 1/3 and 3/10 MHz in the dual frequency mode. The gel-type cosmetics and epidermal-grow-factor-based nano-cosmetics showed the highest absorption rate at 3/10MHz dual frequency. The size of the cosmetic particles decreased by 5-9 %. Furthermore, the temperature rise caused by ultrasound could be visually recognized by the thermochromic pigment in the phantom turning white. We presented a skin-mimicking phantom. The device can be customized according to the size of the ultrasound probe and has the advantage of quantitatively evaluating the transdermal permeability of cosmetics at a low cost. The development of the skin-mimicking phantom will be useful for determining the suitable conditions required to increase the absorption rate of cosmetics using ultrasound.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.472-472
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• 2010

The tomography has played a key role in tokamak plasma diagnostics for image reconstruction. The Phillips-Tikhonov (P-T) regularization method was attempted in this work to reconstruct cross-sectional phantom images of the plasma by minimizing the gradient between adjacent pixel data. Recent studies about the comparison of the several tomographic reconstruction methods showed that the P-T method produced more accurate results. We have studied existing Laplacian matrix used in Phillips-Tikhonov regularization method and developed modified Laplacian matrix (Modified L). The comparison of the reconstruction result by the modified L and existing L showed that modified L produced more accurate result. The difference was significantly pronounced when a portion of plasma was reconstructed. These results can be utilized in the Edge Plasma diagnostics; especially in divertor diagnostics on tokamak a large impact is expected. In addition, accurate reconstruction results from received data in only one direction were confirmed through phantom test by using P-T method with modified L. These results can be applied to the tangentially viewing pin-hole camera diagnostics on tokamak.

• The Journal of the Korea institute of electronic communication sciences
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• v.7 no.5
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• pp.1095-1101
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• 2012

As the amount of data increases explosively, a large scale database system is emerged to store, retrieve and manipulate it. There are several issues in this environments such as, consistency, availability and fault tolerance. In this paper, we address a efficient range-query method where data management services are separated from transaction management services in large-scale database systems. A study had been proposed using partitions to protect independence of two modules and to resolve the phantom problem, but this method was efficient only when range-query is specified by a key. So, we present a new method that can improve the efficiency when range-query is specified by a key attribute as well as other attributes. The presented method can guarantee the independence of separated modules and alleviate overheads for range-query using partial index.

• Journal of Biomedical Engineering Research
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• v.16 no.4
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• pp.395-402
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• 1995

The intravoxel spin phases in magnetic resonance imaging (MRI) usually vary due to susceptibility differences of materials to be imaged. The phase variation in the voxel results in a reduction of the signal intensity. This signal intensity reduction is known as the susceptibility effect in MRI and has been studied extensively. In this paper, a new spectral decomposition technique Is proposed and the signal change due to the susceptibility effect can be analyzed. A pulse sequence for the spectral decomposition of the susceptibility was developed and applied to susceptibility imaging of venous blood possessing paramagnetic properties. The computer simulations and their corresponding experimental results obtained using both a phantom and human volunteers are reported. Key words : susceptibility effect in MRI : spectral decomposition of susceptibility effect.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.7
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• pp.56-63
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• 2016

This paper presents a novel method for detecting a ghost key at the membrane type keyboard, which has additional resistive coating to the membrane film. Also, the optimal ratio of resistances for detecting a ghost key was designed based on the characteristics of the membrane film. The optimal ratio of resistances was considered to be able to detect the worst case (i.e., difference voltage between normal key and ghost key is minimum). The ability of the proposed methods are evaluated by simulation studies in this paper. In order to verify the proposed method, the experiment was carried out with a designed circuit and A/D (analog to digital) in MCU (micro controller unit). The proposed method is implemented into the membrane type keyboard and is verified by experimental results.

• Proceedings of the IEEK Conference
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• 2004.06b
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• pp.529-532
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• 2004

The ECC(Elliptic Curve Cryptogrphics), one of the representative Public Key encryption algorithms, is used in Digital Signature, Encryption, Decryption and Key exchange etc. The key operation of an Elliptic curve cryptosystem is a scalar multiplication, hence the design of a scalar multiplier is the core of this paper. Although an Integer operation is computed in infinite field, the scalar multiplication is computed in finite field through adding points on Elliptic curve. In this paper, we implemented scalar multiplier in Elliptic curve based on the finite field GF($2^{163}$). And we verified it on the Embedded digital system using Xilinx FPGA connected to an EISC MCU. If my design is made as a chip, the performance of scalar multiplier applied to Samsung $0.35 {\mu}m$ Phantom Cell Library is expected to process at the rate of 8kbps and satisfy to make up an encryption processor for the Embedded digital doorphone.

• Proceedings of the Korea Information Processing Society Conference
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• 2005.05a
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• pp.1071-1074
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• 2005

The ECC(Elliptic Curve Cryptogrphics), one of the representative Public Key encryption algorithms, is used in Digital Signature, Encryption, Decryption and Key exchange etc. The key operation of an Elliptic curve cryptosystem is a scalar multiplication, hence the design of a scalar multiplier is the core of this paper. Although an Integer operation is computed in infinite field, the scalar multiplication is computed in finite field through adding points on Elliptic curve. In this paper, we implemented scalar multiplier in Elliptic curve based on the finite field $GF(2^{163})$. And we verified it on the Embedded digital system using Xilinx FPGA connected to an EISC MCU(Agent 2000). If my design is made as a chip, the performance of scalar multiplier applied to Samsung $0.35\;{\mu}m$ Phantom Cell Library is expected to process at the rate of 8kbps and satisfy to make up an encryption processor for the Embedded digital information home system.

• Journal of the Korean Society of Radiology
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• v.15 no.4
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• pp.401-408
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• 2021

Proton therapy using the Bragg peak is one of the radiation therapies and can deliver its maximum energy to the tumor with giving least energy for normal tissue. A cross-sectional image of the human body taken with the computed tomography (CT) has been used for radiation therapy planning. The HU values change according to the tube voltage, which lead to the change in the boundary and thickness of the anatomical structure on the CT image. This study examined the changes in the Bragg peak of the brain region according to the thickness variation in the head phantom composed of several materials using the Geant4. In the phantom composed of a single material, the Bragg peak according to the type of media and the incident energy of the proton beams were calculated, and the reliability of Geant4 code was verified by the Bragg peak. The variation of the peak in the brain region was examined when each thickness of the head phantom was changed. When the thickness of the soft tissue was changed, there was no change in the peak position, and for the skin the change in the peak was small. The change of the peak position was mainly changed when the bone thickness. In particular, when the bone was changed only or the bone was changed together with other tissues, the amount of change in the peak position was the same. It is considered that measurement of the accurate bone thickness in CT images is one of the key factors in depth-dose distribution of the radiation therapy planning.